Startseite UB

2,5-Diphenylfuran-based pure antiestrogens with selectivity for the estrogen receptor alpha

Zimmermann, Jochen and Liebl, Renate and Angerer, Erwin von (2005) 2,5-Diphenylfuran-based pure antiestrogens with selectivity for the estrogen receptor alpha. The Journal of Steroid Biochemistry and Molecular Biology 94 (1-3), pp. 57-66.

Full text not available from this repository.

at PubMed

at publisher (via DOI)


Abstract

The estrogen receptor alpha (ERalpha) is understood to play an important role in the progression of breast cancer. Therefore, pure antiestrogens with a preference for this receptor form are of interest as new agents for the treatment of this malignancy. Several chemical structures with selective binding affinity for ERalpha have been identified and might be useful for the synthesis of ...

plus


Export bibliographical data



Item Type:Article
Date:2005
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
15862950PubMed ID
10.1016/j.jsbmb.2004.12.018DOI
Classification:
NotationType
AnimalsMESH
Breast NeoplasmsMESH
Cell Division/drug effectsMESH
Cell Line, TumorMESH
Estrogen Receptor Modulators/pharmacologyMESH
Estrogen Receptor alpha/antagonists & inhibitorsMESH
FemaleMESH
Furans/chemical synthesisMESH
HumansMESH
MiceMESH
Mice, Inbred StrainsMESH
Organ Size/drug effectsMESH
Structure-Activity RelationshipMESH
Uterus/anatomy & histologyMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:03 Dec 2008 15:26
Last Modified:05 Aug 2009 13:48
Item ID:4783
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact