Beckenlehner, Karin and Bannke, Silke and Spruss, Thilo and Bernhardt, Günther and Schönenberger, Helmut and Schiess, Wilfried (1992) Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo. Journal of cancer research and clinical oncology 118 (8), pp. 591-596.
The effect of hyaluronidase and a combination of hyaluronidase with Adriamycin was investigated on several breast cancer models in vitro and in vivo. In vitro enzyme treatment (using concentrations up to 80,000 IU/1) of murine (MXT-, MXT +/-, and MXT+) and human (MCF-7, ZR-75-1 and T-47-D) breast cancer cell lines did not inhibit tumour cell proliferation (measured by a kinetic crystal violet ...
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|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger|
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
|Subjects:||500 Science > 570 Life sciences|
500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||12 Dec 2008 16:31|
|Last Modified:||13 Mar 2014 18:32|