Startseite UB

Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3

Bernhardt, Günther and Müller, Richard and Gust, Ronald and Reile, Herta and Keller, Christoph and Spruss, Thilo and Schönenberger, Helmut (1992) Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3. Archiv der Pharmazie 325 (2), pp. 93-99.

[img]
Preview
PDF
Download (565kB)

at PubMed


Abstract

The diastereoisomeric dichloro-[1-(2-, 3- and 4-hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes were tested on two human ovarian cancer cell lines NIH: OVCAR-3 and SK-OV-3, both resistant against cisplatin. Dichloro-[threo-1-(3-hydroxyphenyl)-2-phenylethylenediamine]platinum(II) (threo-5-PtCl2) proved to be the most active representative of the new series, producing cytocidal ...

plus


Export bibliographical data

Item Type:Article
Date:1992
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:SFB 234
Identification Number:
ValueType
1605722PubMed ID
Classification:
NotationType
Adenocarcinoma/drug therapyMESH
Antineoplastic Agents/chemical synthesisMESH
FemaleMESH
HumansMESH
Organoplatinum Compounds/chemical synthesisMESH
Ovarian Neoplasms/drug therapyMESH
Tumor Cells, Cultured/drug effectsMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:12 Dec 2008 17:29
Last Modified:13 Mar 2014 18:32
Item ID:4818
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact