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Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound

Schlemmer, Richard and Spruß, Thilo and Bernhardt, Günther and Schönenberger, Helmut (2001) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound. Archiv der Pharmazie 334 (10), pp. 309-317.

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Abstract

In female B6D2F1 mice bearing an MXT-M-3,2 breast cancer graft the level of the phagocytic cells (e.g. of granulocytes and macrophages in the spleen and of granulocytes and monocytes in the blood) is significantly elevated. The positive correlation between the number of the phagocytic cells and the weight of the tumor indicates that the MXT-M-3,2 breast cancer promotes myelopoiesis, presumably by ...

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Item Type:Article
Date:2001
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:SFB 234
Identification Number:
ValueType
11759169PubMed ID
10.1002/1521-4184(200110)334:10<309::AID-ARDP309>3.0.CO;2-8DOI
Classification:
NotationType
Adjuvants, Immunologic/pharmacologyMESH
AnimalsMESH
Antineoplastic Agents/pharmacologyMESH
Breast Neoplasms/pathologyMESH
Cell Division/drug effectsMESH
Cell LineMESH
FemaleMESH
HumansMESH
MiceMESH
Mice, Inbred StrainsMESH
Organoplatinum Compounds/pharmacologyMESH
Phagocytes/drug effectsMESH
Spleen/cytologyMESH
Tumor Cells, CulturedMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:14 Jan 2009 14:56
Last Modified:19 Aug 2010 11:22
Item ID:4842
Owner Only: item control page
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