Dove, Stefan (2004) Picolinic Acids as Inhibitors of Dopamine b-Monooxygenase: QSAR and Putative Binding Site. Archiv der Pharmazie 337 (12), pp. 645-653.
Full text not available from this repository.
Dopamine b-monooxygenase (DBM, EC 184.108.40.206) catalyzes the oxidn. of dopamine into (R)-noradrenaline. DBM inhibitors may act as antihypertensive drugs. A series of 22 picolinic acids substituted in 4- and 5-position was previously synthesized and tested for inhibition of DBM from bovine adrenal medulla. The QSAR of these compds. were investigated by Hansch anal. and comparative mol. field ...
Export bibliographical data
|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)|
|Subjects:||500 Science > 570 Life sciences|
500 Science > 540 Chemistry & allied sciences
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Owner:||Prof. Dr. Stefan Dove|
|Deposited On:||21 Jan 2009 17:45|
|Last Modified:||05 Aug 2009 13:50|