Dove, Stefan and Franke, R. (1991) Model-based LFER parameters and QSAR of ligand-ß-adrenoceptor interactions. I. Equilibrium models and parameters of ß-adrenergic effectuation. Quantitative structure activity relationships 10 (1), pp. 16-22.
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A sep. consideration of ligand-b-adrenoceptor interactions responsible for affinity (recognition, binding) and agonistic activity, resp., is very important for the explanation of mol. events eliciting the activating conformational change of the receptor. Equil. models of b-adrenergic effectuation including receptor activation by agonists and partial agonists, receptor-effector (G-protein) ...
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|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)|
|Subjects:||500 Science > 570 Life sciences|
500 Science > 540 Chemistry & allied sciences
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||No|
|Deposited On:||21 Jan 2009 17:43|
|Last Modified:||05 Aug 2009 13:50|