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Model-based LFER parameters and QSAR of ligand-ß-adrenoceptor interactions. I. Equilibrium models and parameters of ß-adrenergic effectuation

Dove, Stefan and Franke, R. (1991) Model-based LFER parameters and QSAR of ligand-ß-adrenoceptor interactions. I. Equilibrium models and parameters of ß-adrenergic effectuation. Quantitative structure activity relationships 10 (1), pp. 16-22.

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Other URL: http://www3.interscience.wiley.com/journal/113323331/abstract


Abstract

A sep. consideration of ligand-b-adrenoceptor interactions responsible for affinity (recognition, binding) and agonistic activity, resp., is very important for the explanation of mol. events eliciting the activating conformational change of the receptor. Equil. models of b-adrenergic effectuation including receptor activation by agonists and partial agonists, receptor-effector (G-protein) ...

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Item Type:Article
Date:1991
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
1991:464031Other
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Prof. Dr. Stefan Dove
Deposited On:21 Jan 2009 17:43
Last Modified:05 Aug 2009 13:50
Item ID:5414
Owner Only: item control page
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