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On the Rational Selection of Test Series. II. Two-Dimensional Mapping of Intraclass Correlation Matrices (TMIC Method)

Dove, Stefan and Streich, J. and Franke, R. (1980) On the Rational Selection of Test Series. II. Two-Dimensional Mapping of Intraclass Correlation Matrices (TMIC Method). Journal of Medicinal Chemistry 23 (12), pp. 1456-1459.

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Other URL: http://pubs.acs.org/doi/abs/10.1021/jm00186a033


Abstract

A 2-dimensional mapping of intraclass correlation matrixes (TMIC) as a tool in drug design is presented. The variance coeff. obtained with TMIC is somewhat smaller than the corresponding values from multidimensional mapping, however, the differences are marginal. TMIC is a simple and comprehensive method for the selection of optimal test series if the no. of compds. in the starting population ...

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Item Type:Article
Date:1980
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
1980:597545Other
Subjects:500 Science > 510 Mathematics
500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Prof. Dr. Stefan Dove
Deposited On:21 Jan 2009 16:21
Last Modified:05 Aug 2009 13:50
Item ID:5429
Owner Only: item control page
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