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Hydrophobicity and Hydrophobic Interactions I. On the Physical Nature of Aromatic Hydrophobic Substituent Constants

Franke, R. and Dove, Stefan and Kühne, R. (1979) Hydrophobicity and Hydrophobic Interactions I. On the Physical Nature of Aromatic Hydrophobic Substituent Constants. European journal of medicinal chemistry 14 (4), pp. 363-372.

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Abstract

Arom. p-values for 14 meta and para-substituents measured in 8 arom. std. series are analyzed by principal component anal. To reproduce the data within exptl. error, the meta substituents require 2 components, the 1st component reflecting the intrinsic arom. hydrophobicity and the 2nd reflecting electronic correction of the functional groups. Para substituents require 3 components. For both ...

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Item Type:Article
Date:1979
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
1980:57996Other
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Prof. Dr. Stefan Dove
Deposited On:20 Jan 2009 18:16
Last Modified:05 Aug 2009 13:50
Item ID:5432
Owner Only: item control page
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