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Relationships between Structure and Cytotoxicity of Thiourea Derivatives

Franke, R. and Vasilev, G. N. and Dove, Stefan (1979) Relationships between Structure and Cytotoxicity of Thiourea Derivatives. Doklady Bolgarskoj Akademii Nauk (Sofia) 32 (3), pp. 369-375.

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Abstract

The relations between the chem structure of the title compds. (I; R1 = Cl, OH, Me, NHAc, OMe; R2 = H, Cl, Me, OMe, NO2; R3 = alkyl or Ph; n = 1 or 2) and their cytotoxicity were studied by the technique of discriminant anal. To est. the effects of substituents in the substituted Ph ring on cytotoxicity, the hydrophobic substituent const., the Hammett const., and Taft's steric const. were used. ...

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Item Type:Article
Date:1979
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
1980:51715Other
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Prof. Dr. Stefan Dove
Deposited On:20 Jan 2009 16:53
Last Modified:05 Aug 2009 13:50
Item ID:5437
Owner Only: item control page
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