Hollstein, Michael and Lux, Franz and Reile, Herta and Bernhardt, Günther and Schönenberger, Helmut (1993) NAA of platinated DNA after treatment of cancer cells with new platinum complexes. .
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In MCF-7 cells treated with Pt complexes, which differed from cis-(NH3)2PtCl3 by substitution of the NH3-groups with bidentate ligands, the correlation between the degree of DNA platination and the antitumor effect of complexes was examd.
|Additional information (public):||CAN 122:305974 1-6 Pharmacology 15663-27-1; 111112-54-0; 163168-43-2; 163253-99-4 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), THU (Therapeutic use), BIOL (Biological study), USES (Uses) (platinated DNA after treatment of cancer cells with new platinum complexes)|
|Institutions:|| Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger|
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
|Keywords:||Neoplasm inhibitors (platinated DNA after treatment of cancer cells with new platinum complexes); Deoxyribonucleic acids Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (platinated DNA after treatment of cancer cells with new platinum complexes); platinum complex antitumor platinated DNA|
|Subjects:||500 Science > 570 Life sciences|
500 Science > 540 Chemistry & allied sciences
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Partially|
|Deposited On:||15 Jan 2009 16:28|
|Last Modified:||01 Feb 2012 11:23|
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