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NAA of platinated DNA after treatment of cancer cells with new platinum complexes

Hollstein, Michael and Lux, Franz and Reile, Herta and Bernhardt, Günther and Schönenberger, Helmut (1993) NAA of platinated DNA after treatment of cancer cells with new platinum complexes. .

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Abstract

In MCF-7 cells treated with Pt complexes, which differed from cis-(NH3)2PtCl3 by substitution of the NH3-groups with bidentate ligands, the correlation between the degree of DNA platination and the antitumor effect of complexes was ...

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Item Type:Other
Date:1993
Additional information (public):CAN 122:305974 1-6 Pharmacology 15663-27-1; 111112-54-0; 163168-43-2; 163253-99-4 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), THU (Therapeutic use), BIOL (Biological study), USES (Uses) (platinated DNA after treatment of cancer cells with new platinum complexes)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
1995:453678Other
Keywords:Neoplasm inhibitors (platinated DNA after treatment of cancer cells with new platinum complexes); Deoxyribonucleic acids Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (platinated DNA after treatment of cancer cells with new platinum complexes); platinum complex antitumor platinated DNA
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Guenther Bernhardt
Deposited On:15 Jan 2009 15:28
Last Modified:01 Feb 2012 10:23
Item ID:5479
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