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NAA of platinated DNA after treatment of cancer cells with new platinum complexes

Hollstein, Michael and Lux, Franz and Reile, Herta and Bernhardt, Günther and Schönenberger, Helmut (1993) NAA of platinated DNA after treatment of cancer cells with new platinum complexes. .

Full text not available from this repository.

Abstract

In MCF-7 cells treated with Pt complexes, which differed from cis-(NH3)2PtCl3 by substitution of the NH3-groups with bidentate ligands, the correlation between the degree of DNA platination and the antitumor effect of complexes was examd.

Item Type:

Other

Additional information (public):

CAN 122:305974 1-6 Pharmacology 15663-27-1; 111112-54-0; 163168-43-2; 163253-99-4 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), THU (Therapeutic use), BIOL (Biological study), USES (Uses) (platinated DNA after treatment of cancer cells with new platinum complexes)

Institutions:

Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)

Identification Number:

Value	Type
1995:453678	Other

Keywords:

Neoplasm inhibitors (platinated DNA after treatment of cancer cells with new platinum complexes); Deoxyribonucleic acids Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (platinated DNA after treatment of cancer cells with new platinum complexes); platinum complex antitumor platinated DNA

Subjects:

500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences

Status:

Published

Refereed:

Yes, this version has been refereed

Created at the University of Regensburg:

Partially

Owner:

Guenther Bernhardt

Deposited On:

15 Jan 2009 16:28