Deutsch
Mengel, A. and Reiser, O. and Aube, J. (2008) Synthesis and structural study of cyclic 5-aminovaleric acid-linked beta-Ala-beta-Ala dipeptides. Bioorganic & Medicinal Chemistry Letters 18 (22), pp. 5975-5977.
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Abstract
5-Aminovaleric acid and ornithine were evaluated as linkers for the cyclization of beta-dipeptides. Two linked examples of beta-Ala-beta-Ala were prepared by standard coupling methods and their conformations probed by NMR, CD, and computational means. The data suggest that these non- or monosubstituted versions of the target compounds are flexible in solution.
| Item Type: | Article | ||||||
|---|---|---|---|---|---|---|---|
| Additional information (public): | Mengel, Anne; Reiser, Oliver; Aube, Jeffrey | ||||||
| Institutions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser | ||||||
| Identification Number: |
| ||||||
| Subjects: | 500 Science > 540 Chemistry & allied sciences | ||||||
| Status: | Published | ||||||
| Refereed: | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg: | Partially | ||||||
| Owner: | Oliver Reiser | ||||||
| Deposited On: | 09 Feb 2009 11:37 | ||||||
| Last Modified: | 16 Nov 2009 15:38 | ||||||
| Item ID: | 5714 |
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