Prediger, I. and Weiss, T. and Reiser, O. (2008) Facile access to 2-arylindolines and 2-arylindoles by microwave-assisted tandem radical cyclization. Synthesis (14), pp. 2191-2198.
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A new route providing access to 2-arylindoles has been developed. The synthesis consists of a tin-mediated tandem radical cyclization of appropriate precursors to form 2,3-disubstituted dihydroindoles, which in turn are oxidized to yield the corresponding 2-arylindoles. The reactions proceed smoothly under microwave irradiation, furnishing the desired products in good yields.
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|Additional Information (public):||Prediger, Inga; Weiss, Torsten; Reiser, Oliver|
|Institutions:||Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser|
|Dewey Decimal Classification:||500 Science > 540 Chemistry & allied sciences|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||09 Feb 2009 09:59|
|Last Modified:||16 Nov 2009 14:37|