Synthesis and Structure of a Stabilized 10-Membered Cyclic Enediyne

Pitsch, W. and Klein, M. and Zabel, M. and König, B. (2002) Synthesis and Structure of a Stabilized 10-Membered Cyclic Enediyne. J. Org. Chem. 67, 6805 - 6807.

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Abstract

The synthesis and structure of an acetal protected 10-membered cyclic enediyne-1,2-diol rac-10 is reported. The conformational constrain of the unsaturated macrocycle by the acetal protection group prevents the thermal cyclization reaction of the endiyne during synthesis and purification.

Item Type:Article
Institutions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Chemistry and Pharmacy > Institut für Anorganische Chemie > Arbeitskreis Prof. Dr. Nikolas Korber
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.1021/jo025998qDOI
12227813 PubMed ID
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner:Regina Hoheisel
Deposited On:05 Mar 2009 11:54
Last Modified:09 Nov 2010 16:57
Item ID:6224
Owner Only: item control page