Gallmeier, H.-C. and König, B. (2003) Heteroaromatic Oligoamides with dDNA Affinity (review). Eur. J. Org. Chem., 3473 - 3483.
Full text not available from this repository.
Heteroaromatic oligoamides are selective ligands for sequence-specific dDNA binding, many artificial oligoamides modeled on naturally occurring compounds and their dDNA binding motifs having been prepared over the last ten years. The large number of reported individual compounds does not allow each structure to be covered within the scope of this review, so we concentrate on examples of the most successful linear and tethered oligoamide structures, such as hairpin, H-pin, or cyclic structures, and the ensemble of heteroaromatic amino acids used as their building blocks. This provides an overview of which chemical structures are currently in use for sequence-specific dDNA recognition by artificial ligands and what they can achieve. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
|Institutions:||Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König|
|Projects:||GRK 760, Graduiertenkolleg Medizinische Chemie|
|Keywords:||DNA binding;Heterocycles;Molecular recognition;Oligoamides|
|Subjects:||500 Science > 540 Chemistry & allied sciences|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||05 Mar 2009 10:54|
|Last Modified:||09 Nov 2010 15:48|