Deutsch
Bonauer, C. and Zabel, M. and König, B. (2004) Synthesis and peptide binding properties of methoxypyrrole amino acids (MOPAS). Org. Lett. 6, 1349 - 1352.
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Abstract
Methoxypyrrole amino acids (MOPAS) have been prepared and were introduced into small peptides with hairpin structures. The intra- and intermolecular binding properties of this heterocyclic amino acid mimicking a dipeptido beta-strand was investigated by NMR titration and X-ray crystal structure analysis. The data reveal a hydrogen bonding pattern that is complementary to a peptide beta-sheet.
| Item Type: | Article | ||||||
|---|---|---|---|---|---|---|---|
| Institutions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König Chemistry and Pharmacy > Institut für Anorganische Chemie > Arbeitskreis Prof. Dr. Nikolas Korber | ||||||
| Projects: | GRK 760, Graduiertenkolleg Medizinische Chemie | ||||||
| Identification Number: |
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| Subjects: | 500 Science > 540 Chemistry & allied sciences | ||||||
| Status: | Published | ||||||
| Refereed: | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg: | Yes | ||||||
| Owner: | Regina Hoheisel | ||||||
| Deposited On: | 05 Mar 2009 11:54 | ||||||
| Last Modified: | 09 Nov 2010 15:51 | ||||||
| Item ID: | 6242 |
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