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Synthesis and peptide binding properties of methoxypyrrole amino acids (MOPAS).

Bonauer, C. and Zabel, M. and König, B. (2004) Synthesis and peptide binding properties of methoxypyrrole amino acids (MOPAS). Org. Lett. 6, 1349 - 1352.

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Abstract

Methoxypyrrole amino acids (MOPAS) have been prepared and were introduced into small peptides with hairpin structures. The intra- and intermolecular binding properties of this heterocyclic amino acid mimicking a dipeptido beta-strand was investigated by NMR titration and X-ray crystal structure analysis. The data reveal a hydrogen bonding pattern that is complementary to a peptide ...

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Item Type:Article
Date:2004
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Chemistry and Pharmacy > Institut für Anorganische Chemie > Arbeitskreis Prof. Dr. Nikolaus Korber
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.1021/ol049855xDOI
15101739PubMed ID
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:05 Mar 2009 10:54
Last Modified:09 Nov 2010 14:51
Item ID:6242
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