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Design, Synthesis, and Evaluation of a Biomimetic Artificial Photolyase Model

Wiest, O. and Harrison, C.B. and Saettel, N. J. and Cibulka, R. and Sax, M. and König, B. (2004) Design, Synthesis, and Evaluation of a Biomimetic Artificial Photolyase Model. J. Org. Chem. 69, 8183 – 8185.

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Abstract

Two new artificial photolyase models that recognize pyrimidine dimers in protic and aprotic organic solvents as well as in water through a combination of charge and hydrogen-bonding interactions and use a mimic of the flavine to achieve repair through reductive photoinduced electron transfer are presented. Fluorescence and NMR titration studies show that it forms a 1:1 complex with pyrimidine ...

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Item Type:Article
Date:2004
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.1021/jo0494329DOI
15549785 PubMed ID
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:05 Mar 2009 10:54
Last Modified:09 Nov 2010 13:20
Item ID:6247
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