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Luminescent Crown Ether Amino Acids - Selective Binding to N-terminal Lysine in Peptides

Mandl, C. P. and König, B. (2005) Luminescent Crown Ether Amino Acids - Selective Binding to N-terminal Lysine in Peptides. J. Org. Chem. 70, 670 – 674.

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Abstract

Crown ether amino acids (CEAAs) with a luminescent phthalic ester or phthalimide moiety have been prepared. Simple peptide chemistry covalently tethers the macrocycles to give ditopic ammonium-ion binders. The binding events of both crown ether groups are monitored independently by changes of their specific emission properties. The affinity of the bis-CEAA to bis-ammonium ions is distance ...

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Item Type:Article
Date:2005
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.1021/jo048105yDOI
15651816 PubMed ID
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:05 Mar 2009 10:54
Last Modified:09 Nov 2010 13:03
Item ID:6250
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