Deutsch
Dirscherl, G. and Knape, R. and Hanson, P. and König, B. (2007) Solid Phase Synthesis of Metal-Complex containing Peptides. Tetrahedron 63, 4918 – 4928.
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Abstract
We report the synthesis of Fmoc protected single amino acid chelates (SAAC) and their metal complexes. The modified amino acids are suitable for solid-phase peptide synthesis. The use of 4-hydroxymethylbenzoic acid AM (HMBA-AM) resin allows the nucleophilic cleavage of the peptide–metal complexes from the resin without decomplexation.
| Item Type: | Article | ||||
|---|---|---|---|---|---|
| Institutions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König | ||||
| Projects: | GRK 760, Graduiertenkolleg Medizinische Chemie | ||||
| Identification Number: |
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| Keywords: | Solid-phase peptide synthesis; Metal complex; Single amino acid chelate | ||||
| Subjects: | 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Owner: | Regina Hoheisel | ||||
| Deposited On: | 05 Mar 2009 11:55 | ||||
| Last Modified: | 08 Nov 2010 16:06 | ||||
| Item ID: | 6279 |
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