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Synthesis of new Ca-tetrasubstituted a-amino acids

Grauer, Andreas and König, Burkhard (2009) Synthesis of new Ca-tetrasubstituted a-amino acids. Beilstein Journal of Organic Chemistry 5 (5).

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Abstract

Cα-Tetrasubstituted α-amino acids are important building blocks for the synthesis of peptidemimetics with stabilized secondary structure, because of their ability to rigidify the peptide backbone. Recently our group reported a new class of cyclic Cα-tetrasubstituted tetrahydrofuran α-amino acids prepared from methionine and aromatic aldehydes. We now report the extension of this methodology to ...

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Item Type:Article
Date:2009
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.3762/bjoc.5.5DOI
19259341 PubMed ID
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Regina Hoheisel
Deposited On:05 Jun 2009 14:24
Last Modified:08 Nov 2010 10:18
Item ID:7278
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