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Boosting GABA improves impaired auditory temporal resolution in the gerbil

Gleich, Otto and Hamann, Ingo and Klump, Georg M. and Kittel, Malte and Strutz, Jürgen (2003) Boosting GABA improves impaired auditory temporal resolution in the gerbil. Neuroreport 14 (14), pp. 1877-1880.

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Abstract

Elderly humans often not only experience peripheral hearing loss but also suffer from more central deficits in temporal auditory processing affecting speech perception. Impaired auditory temporal resolution has also been observed in old rodents. Other studies have demonstrated a reduction of GABAergic function in the auditory pathway of old animals. Here we test the hypothesis that deficits in ...

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Item Type:Article
Date:2003
Institutions:Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Identification Number:
ValueType
14534439PubMed ID
10.1097/01.wnr.0000089569.45990.74DOI
Classification:
NotationType
Acoustic StimulationMESH
AgingMESH
AnimalsMESH
Anticonvulsants/pharmacologyMESH
Auditory Pathways/drug effectsMESH
Auditory Perceptual Disorders/drug therapyMESH
Auditory Threshold/drug effectsMESH
Behavior, AnimalMESH
Disease Models, AnimalMESH
Dose-Response Relationship, DrugMESH
FemaleMESH
Gerbillinae/physiologyMESH
MaleMESH
Random AllocationMESH
Vigabatrin/pharmacologyMESH
gamma-Aminobutyric Acid/analogs & derivativesMESH
Subjects:500 Science > 570 Life sciences
500 Science > 590 Zoological sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Otto Gleich
Deposited On:18 Jun 2009 14:30
Last Modified:05 Aug 2009 13:57
Item ID:7557
Owner Only: item control page
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