Hellerbrand, Claus and Mühlbauer, Marcus and Wallner, Susanne and Schuierer, Marion and Behrmann, Iris and Bataille, Frauke and Weiss, Thomas and Schölmerich, Jürgen and Bosserhoff, Anja-Katrin (2006) Promoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma. Carcinogenesis 27 (1), pp. 64-72.
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Other URL: http://dx.doi.org/10.1093/carcin/bgi201
The methylthioadenosine phosphorylase (MTAP) gene is localized in the chromosomal region 9p21. Here, frequently homozygous deletions occur in several kinds of cancer associated with the loss of tumour suppressor genes as p16 and p15. The aim of this study was to analyse MTAP expression in hepatocellular carcinoma (HCC) and to get an insight into the regulation and functional role of MTAP in ...
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|Institutions:||Medicine > Lehrstuhl für Innere Medizin I|
Medicine > Lehrstuhl für Chirurgie
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||07 Dec 2006|
|Last Modified:||13 Mar 2014 09:42|