Winner, Beate and Geyer, Martin and Couillard-Despres, Sebastien and Aigner, Robert and Bogdahn, Ulrich and Aigner, Ludwig and Kuhn, Georg and Winkler, Jürgen (2006) Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb. Experimental neurology 197 (1), pp. 113-121.
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Dopaminergic loss is known to be one of the major hallmarks of Parkinson disease (PD). In addition to its function as a neurotransmitter, dopamine plays significant roles in developmental and adult neurogenesis. Both dopaminergic deafferentation and stimulation modulate proliferation in the subventricular zone (SVZ)/olfactory bulb system as well as in the hippocampus. Here, we study the impact of ...
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|Institutions:||Medicine > Lehrstuhl für Neurologie|
|Keywords:||Parkinson disease; Lesion; Adult neurogenesis; Neural progenitor/stem cell; BrdU; TH; Pax-6; Cell fate; 6-OHDA|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||07 Dec 2006|
|Last Modified:||13 Mar 2014 09:42|