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Tenascin-C protein is induced by transforming growth factor-beta1 but does not correlate with time to tumor progression in high-grade gliomas

Hau, Peter and Kunz-Schughart, Leoni A. and Rümmele, Petra and Arslan, Füsun and Dörfelt, Anett and Koch, Horst and Lohmeier, Annette and Hirschmann, Birgit and Müller, Adolf and Bogdahn, Ulrich and Bosserhoff, Anja-Katrin (2006) Tenascin-C protein is induced by transforming growth factor-beta1 but does not correlate with time to tumor progression in high-grade gliomas. Journal of neuro-oncology 77 (1), pp. 1-7.

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Other URL: http://dx.doi.org/10.1007/s11060-005-9000-5


Abstract

BACKGROUND: Tenascin-C is an extracellular matrix protein known to correlate with prognosis in patients with glioblastoma, probably by stimulation of invasion and neoangiogenesis. Transforming Growth Factor-beta1 (TGF-beta1) plays an important role in the biology of high-grade gliomas, partly by regulating invasion of these tumors into parenchyma. This study was designed to evaluate if TGF-beta1 ...

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Item Type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Neurologie
Identification Number:
ValueType
10.1007/s11060-005-9000-5DOI
16292494PubMed ID
Keywords:anaplastic astrocytoma; glioblastoma; high-grade gliomas; induction; prognosis; Tenascin-C; TGF-ß1
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:07 Dec 2006
Last Modified:13 Mar 2014 09:42
Item ID:794
Owner Only: item control page

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