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Enhanced Y1-receptor-mediated vasoconstrictive action of neuropeptide Y (NPY) in superior mesenteric arteries in portal hypertension

Wiest, Reiner and Jurzik, Lars and Moleda, Lukas and Froh, Matthias and Schnabl, Bernd and Hörsten, Stephan von and Schölmerich, Juergen and Straub, Rainer H. (2006) Enhanced Y1-receptor-mediated vasoconstrictive action of neuropeptide Y (NPY) in superior mesenteric arteries in portal hypertension. Journal of hepatology 44 (3), pp. 512-519.

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Other URL: http://dx.doi.org/10.1016/j.jhep.2005.08.023


Abstract

BACKGROUND/AIMS: Vascular hyporeactivity to catecholamines contributes to arterial vasodilation and hemodynamic dysregulation in portal hypertension. Neuropeptide Y (NPY) is a sympathetic neurotransmitter facilitating adrenergic vasoconstriction via Y1-receptors on the vascular smooth muscle. Therefore, we investigated its role for vascular reactivity in the superior mesenteric artery (SMA) of ...

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Item Type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1016/j.jhep.2005.08.023DOI
16324766PubMed ID
Keywords:Portal hypertension; Splanchnic circulation; Neuropeptide Y; Vasodilation
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:08 Dec 2006
Last Modified:13 Mar 2014 09:43
Item ID:798
Owner Only: item control page

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