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Pharmacogenomics of cholesterol-lowering therapy

Schmitz, Gerd and Langmann, Thomas (2006) Pharmacogenomics of cholesterol-lowering therapy. Vascular pharmacology 44 (2), pp. 75-89.

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Other URL: http://dx.doi.org/10.1016/j.vph.2005.07.012


Abstract

The prevention of cardiovascular disease is critically dependent on lipid-lowering therapy, including 3-hydroxymethyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins), cholesterol absorption inhibitors, bile acid resins, fibrates, and nicotinic acid. Although these drugs are generally well tolerated, severe adverse effects can occur in a minority of patients. Furthermore, a ...

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Item Type:Article
Date:February 2006
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Identification Number:
ValueType
16337220PubMed ID
10.1016/j.vph.2005.07.012DOI
Keywords:HMG-CoA reductase inhibitors; Pharmacogenomics; Pharmacogenetics; Polymorphisms
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Ute Lange
Deposited On:08 Dec 2006
Last Modified:05 Aug 2009 13:24
Item ID:800
Owner Only: item control page
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