Schulte-Mattler, W. J. and Martinez-Castrillo, J. C. (2006) Botulinum toxin therapy of migraine and tension-type headache: comparing different botulinum toxin preparations. European journal of neurology : the official journal of the European Federation of Neurological Societies 13 (Suppl ), pp. 51-54.
Download (84kB) - Repository staff only
Most of the initial reports on botulinum toxin in tension-type headache (TTH) and in migraine were positive. Unfortunately, these results were not reproduced in well-designed, randomized controlled trials. So far, doses from 20 U (Botox) to 500 U (Dysport) have been studied in patients with chronic TTH, and doses from 16 to 200 U (Botox) in patients with migraine. Overall, there is no evidence for a beneficial effect of botulinum toxin, although trends favoring botulinum toxin were reported. Experience with botulinum toxin type B (Myobloc/NeuroBloc) is limited and similar to the experience with the type A. Thus, a widespread use of botulinum toxin therapy in headache can currently not be recommended.
|Institutions:||Medicine > Lehrstuhl für Neurologie|
|Keywords:||botulinum toxin; headache; migraine; tensiontype headache; therapy|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||19 Jan 2007|
|Last Modified:||20 Jul 2011 20:50|