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Use of donor serum to prevent passive transfer of hyperacute rejection

Wang, Jue and Geissler, Edward K. and Fechner, John H. and Burlingham, William J. and Knechtle, Stuart J. (1994) Use of donor serum to prevent passive transfer of hyperacute rejection. Journal of surgical research 57 (1), pp. 150-155.

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Abstract

Organ transplantation in presensitized recipients continues to be contraindicated for heart and kidney recipients due to the risk of hyperacute rejection, which has no known treatment at this time. We tested whether donor serum, which contains soluble MHC class I antigen, is able to neutralize the effect of anti-donor antibody in the recipient and prevent hyperacute or accelerated rejection. A ...

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Item Type:Article
Date:1994
Institutions:Medicine > Lehrstuhl für Chirurgie
Identification Number:
ValueType
8041130PubMed ID
10.1006/jsre.1994.1123DOI
Classification:
NotationType
AnimalsMESH
Graft Rejection/prevention & controlMESH
Graft SurvivalMESH
Heart TransplantationMESH
Histocompatibility Antigens Class I/immunologyMESH
Immunization, PassiveMESH
MaleMESH
Myocardium/pathologyMESH
RatsMESH
Rats, Inbred ACI/immunologyMESH
Rats, Inbred LewMESH
Time FactorsMESH
Tissue DonorsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Universitätsbibliothek Regensburg
Deposited On:22 Sep 2009 12:16
Last Modified:13 Mar 2014 11:02
Item ID:9552
Owner Only: item control page

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