Optimization of Interfaces for Genosensors Based on Thiol Layers on Gold Films

URN to cite this document: urn:nbn:de:bvb:355-opus-902

Wrobel, Nadia (2002) Optimization of Interfaces for Genosensors Based on Thiol Layers on Gold Films. PhD, Universität Regensburg

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Abstract (German)

Ziel der Arbeit war eine Optimierung der Oberflächenpräparation für DNA-Biosensoren. Diese Oberflächenpräparation umfasst mehrere Schritte: Selbstorganisation von Alkylthiolen auf einer Metallelektrode gefolgt von der Immobilisierung von Rezeptormolekülen (hier DNA-Oligomere) an die Thiolschicht mittels chemischer Reaktionen. In jedem der Schritte konnten Probleme identifiziert werden, die den ...


Translation of the abstract (English)

The task of this thesis was the optimization of the preparation of interfaces for DNA biosensors. The interface preparation included several steps: Self assembly of a thiol layer on a metal electrode is followed by a tethering (immobilization) of receptor molecules (here DNA-oligomers) to the thiol molecules via a chemical reaction. During each step some limitations have been identified, which ...


Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:9 July 2002
Referee:Otto S. Wolfbeis
Date of exam:23 July 2001
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Otto S. Wolfbeis)
Keywords:Sensor , DNS , Gold , Thiole , , sensor , DNA , gold , thiol
Subjects:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited On:21 Oct 2009 13:41
Last Modified:13 Mar 2014 11:09
Item ID:9934
Owner Only: item control page


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