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Optimization of Interfaces for Genosensors Based on Thiol Layers on Gold Films

URN to cite this document: urn:nbn:de:bvb:355-opus-902

Wrobel, Nadia (2002) Optimization of Interfaces for Genosensors Based on Thiol Layers on Gold Films. PhD, Universität Regensburg

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Abstract (German)

Ziel der Arbeit war eine Optimierung der Oberflächenpräparation für DNA-Biosensoren. Diese Oberflächenpräparation umfasst mehrere Schritte: Selbstorganisation von Alkylthiolen auf einer Metallelektrode gefolgt von der Immobilisierung von Rezeptormolekülen (hier DNA-Oligomere) an die Thiolschicht mittels chemischer Reaktionen. In jedem der Schritte konnten Probleme identifiziert werden, die den ...

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Translation of the abstract (English)

The task of this thesis was the optimization of the preparation of interfaces for DNA biosensors. The interface preparation included several steps: Self assembly of a thiol layer on a metal electrode is followed by a tethering (immobilization) of receptor molecules (here DNA-oligomers) to the thiol molecules via a chemical reaction. During each step some limitations have been identified, which ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:9 July 2002
Referee:Otto S. Wolfbeis
Date of exam:23 July 2001
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Otto S. Wolfbeis)
Keywords:Sensor , DNS , Gold , Thiole , , sensor , DNA , gold , thiol
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:21 Oct 2009 13:41
Last Modified:13 Mar 2014 11:09
Item ID:9934
Owner Only: item control page
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