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Adaptive immune responses against parvovirus B19 in patients with myocardial disease.

Lindner, Juha and Noutsias, Michel and Lassner, Dirk and Wenzel, Jürgen and Schultheiss, Heinz-Peter and Kuehl, Uwe and Modrow, Susanne (2009) Adaptive immune responses against parvovirus B19 in patients with myocardial disease. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 44 (1), pp. 27-32.

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Abstract

BACKGROUND: Parvovirus B19 (B19V)-DNA is frequently detected in endomyocardial biopsies (EMBs) from patients with acute myocarditis (AMC) and dilated cardiomyopathy (DCM), but also in various healthy tissues. The clinical relevance of this DNA-persistence is unclear. OBJECTIVES: To investigate potential pathogenic influences of B19V-DNA in EMBs, we analyzed B19V-specific adaptive immune responses ...

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Item Type:Article
Date:January 2009
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
18980860PubMed ID
10.1016/j.jcv.2008.09.007DOI
Classification:
NotationType
AdultMESH
AgedMESH
Antibodies, Viral/bloodMESH
Blotting, WesternMESH
Cardiomyopathies/virologyMESH
DNA, Viral/bloodMESH
Enzyme-Linked Immunosorbent AssayMESH
FemaleMESH
HumansMESH
Immunoglobulin G/bloodMESH
Immunoglobulin M/bloodMESH
MaleMESH
Middle AgedMESH
Parvoviridae Infections/immunologyMESH
Parvovirus B19, Human/immunologyMESH
Polymerase Chain ReactionMESH
T-Lymphocytes/immunologyMESH
Viral LoadMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Dr. Jürgen Wenzel
Deposited On:28 Oct 2009 08:31
Last Modified:13 Mar 2014 11:11
Item ID:9992
Owner Only: item control page

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