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Publikationen von Bernhardt, Günther

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Anzahl der Einträge: 151.

Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki und Buschauer, Armin (2016) Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor. Pharmacological Research 114, S. 13-26. Volltext nicht vorhanden.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter, Elz, Sigurd und Strasser, Andrea (2016) Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. Pharmacological Research 113, S. 610-625. (Im Druck) Volltext nicht vorhanden.

Kuhn, Kilian K., Ertl, Thomas, Dukorn, Stefanie, Keller, Max, Bernhardt, Günther, Reiser, Oliver und Buschauer, Armin (2016) High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling. Journal of Medicinal Chemistry 59 (13), S. 6045-6058. Volltext nicht vorhanden.

Edalat, Lena, Stegen, Benjamin, Klumpp, Lukas, Haehl, Erik, Schilbach, Karin, Lukowski, Robert, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin, Zips, Daniel, Ruth, Peter und Huber, Stephan M. (2016) BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget 7 (12), S. 14259-14278. Volltext nicht vorhanden.

Obreque-Balboa, José-Esteban, Sun, Qiu, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2016) Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization. European Journal of Medicinal Chemistry 109, S. 124-133. Volltext nicht vorhanden.

Lieb, Sebastian, Michaelis, Stefanie, Plank, Nicole, Bernhardt, Günther, Buschauer, Armin und Wegener, Joachim (2016) Label-free analysis of GPCR-stimulation: The critical impact of cell adhesion. Pharmacological Research 108 (June), S. 65-74. Volltext nicht vorhanden.

Keller, Max, Kuhn, Kilian K., Einsiedel, Jürgen, Hübner, Harald, Biselli, Sabrina, Mollereau, Catherine, Wifling, David, Svobodova, Jaroslava, Bernhardt, Günther, Cabrele, Chiara, Vanderheyden, Patrick, Gmeiner, Peter und Buschauer, Armin (2016) Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples. Journal of Medicinal Chemistry 59 (5), S. 1925-1945. Volltext nicht vorhanden.

Keller, Max, Schindler, Lisa, Bernhardt, Günther und Buschauer, Armin (2015) Towards labeled argininamide-type NPY Y1 receptor antagonists: Identification of a favorable propionylation site in BIBO3304. Archiv der Pharmazie 348 (6), S. 390-398. Volltext nicht vorhanden.

Rothenhöfer, Martin, Grundmann, Marco, Bernhardt, Günther, Matysik, Frank-Michael und Buschauer, Armin (2015) High performance anion exchange chromatography with pulsed amperometric detection (HPAEC–PAD) for the sensitive determination of hyaluronan oligosaccharides. Journal of Chromatography B 988 (C), S. 106-115. Volltext nicht vorhanden.

Wifling, David, Bernhardt, Günther, Dove, Stefan und Buschauer, Armin (2015) The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. PLoS One 10 (1), S. 1-14.

Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther und Buschauer, Armin (2015) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem 10 (1), S. 83-93. Volltext nicht vorhanden.

Kagermeier, Nicole, Werner, Kristin, Keller, Max, Baumeister, Paul, Bernhardt, Günther, Seifert, Roland und Buschauer, Armin (2015) Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists. Bioorganic & Medicinal Chemistry 23 (14), S. 3957-3969. Volltext nicht vorhanden.

Huber, Stefan, Huettner, Johannes Philip, Kristina, Hacker, Bernhardt, Günther, König, Jörg und Buschauer, Armin (2015) Esters of bendamustine are by far more potent cytotoxic agents than the parent compound against human sarcoma and carcinoma cells. PLoS One 10 (7), PLoSe0133743.

Keller, Max, Tränkle, Christian, She, Xueke, Pegoli, Andrea, Bernhardt, Günther, Buschauer, Armin und Read, Roger W. (2015) M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. Bioorganic & Medicinal Chemistry 23 (14), S. 3970-3990. Volltext nicht vorhanden.

Wifling, David, Löffel, Karolin, Nordemann, Uwe, Strasser, Andrea, Bernhardt, Günther, Dove, Stefan, Seifert, Roland und Buschauer, Armin (2015) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology 172, S. 785-798. Volltext nicht vorhanden.

Keller, Max, Weiss, Stefan, Hutzler, Christoph, Kuhn, Kilian K., Mollereau, Catherine, Dukorn, Stefanie, Schindler, Lisa, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2015) N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time. Journal of Medicinal Chemistry 58 (22), S. 8834-8849. Volltext nicht vorhanden.

Huber, Stefan, Antoni, Frauke, Schickaneder, Christian, Schickaneder, Helmut, Bernhardt, Günther und Buschauer, Armin (2015) Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC. Journal of Pharmaceutical and Biomedical Analysis 104, S. 137-143. Volltext nicht vorhanden.

Huber, Stefan, Wege, Anja K., Bernhardt, Günther, Buschauer, Armin und Brockhoff, Gero (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A 87 (8), S. 707-716. Volltext nicht vorhanden.

Schickaneder, Helmut, Buschauer, Armin, Bernhardt, Günther, Schickaneder, Christian, Limmert, Michael, Huber, Stefan, Lubbe, Mathias und Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof. Volltext nicht vorhanden.

Keller, Max, Kaske, Melanie, Holzammer, Tobias, Bernhardt, Günther und Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), S. 6303-6322. Volltext nicht vorhanden.

Berlicki, Lukasz, Kaske, Melanie, Gutierrez-Abad, Raquel , Bernhardt, Günther , Illa, Ona , Ortuño, Rosa , Cabrele, Chiara , Buschauer, Armin und Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), S. 8422-8431. Volltext nicht vorhanden.

Nordemann, Uwe, Wifling, David, Schnell, David, Bernhardt, Günther, Stark, Holger, Seifert, Roland und Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie, Ochoa Puentes, Cristian, Sun, Qiu, Bause, Manuel, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), S. 1773-1778. Volltext nicht vorhanden.

Ochoa-Puentes, Cristian, Bauer, Stefanie, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin und König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), S. 393-396. Volltext nicht vorhanden.

Pluym, Nikola, Baumeister, Paul, Keller, Max, Bernhardt, Günther und Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), S. 587-593. Volltext nicht vorhanden.

Ertel, Miriam, Bernhardt, Günther, Nink, Jörg und Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems. Volltext nicht vorhanden.

Memminger, Martin, Keller, Max, Lopuch, Miroslaw, Pop, Nathalie, Bernhardt, Günther, von Angerer, Erwin und Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Rothenhöfer, Martin, Scherübl, Rosmarie, Bernhardt, Günther, Heilmann, Jörg und Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, S. 169-77. Volltext nicht vorhanden.

Birnkammer, Tobias, Spickenreither, Anja, Brunskole, Irena, Lopuch, Miroslaw, Kagermeier, Nicole, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd und Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), S. 1147-1160. Volltext nicht vorhanden.

Grundmann, Marco, Rothenhöfer, M., Bernhardt, Günther, Buschauer, Armin und Matysik, Frank-Michael (2012) Fast counter-electroosmotic capillary electrophoresis-time-of-flight mass spectrometry of hyaluronan oligosaccharides. Analytical and Bioanalytical Chemistry : Anal. Bioanal. Chem. 402, S. 2617-2623. Volltext nicht vorhanden.

Posavec, Damir, Zabel, Manfred, Bogner, Udo, Bernhardt, Günther und Knör, Günther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. Organic & biomolecular chemistry 10 (35), S. 7062-7069.

Braun, Stephan, Botzki, Alexander, Salmen, Sunnhild, Textor, Christian, Bernhardt, Günther, Dove, Stefan und Buschauer, Armin (2011) Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase. European Journal of Medicinal Chemistry 46 (9), S. 4419-4429. Volltext nicht vorhanden.

Pluym, Nikola, Brennauer, Albert, Keller, Max, Ziemek, Ralf, Pop, Nathalie, Bernhardt, Günther und Buschauer, Armin (2011) Application of the guanidine – acylguanidine bioisosteric approach to argininamide-type NPY Y2 receptor antagonists. ChemMedChem 6 (9), S. 1727-1738. Volltext nicht vorhanden.

Keller, Max, Bernhardt, Günther und Buschauer, Armin (2011) [3H]UR-MK136 - a highly potent and selective radioligand for neuropeptide Y Y1 receptors. ChemMedChem 6 (9), S. 1566-1571. Volltext nicht vorhanden.

Pop, Nathalie, Igel, Patrick, Brennauer, Albert, Cabrele, Chiara, Bernhardt, Günther, Seifert, Roland und Buschauer, Armin (2011) Functional reconstitution of human neuropeptide Y (NPY) Y2 and Y4 receptors in Sf9 insect cells. Journal of Receptors and Signal Transduction 31 (4), S. 271-285. Volltext nicht vorhanden.

Keller, Max, Erdmann, Daniela, Teng, Shangjun, Pop, Nathalie, Pluym, Nikola, Bernhardt, Günther und Buschauer, Armin (2011) Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools. Bioorganic & Medicinal Chemistry 19 (9), S. 2859-2878. Volltext nicht vorhanden.

Ochoa Puentes, Cristian, Höcherl, Peter, Kühnle, Matthias, Bauer, Stefanie, Kürger, Kira, Bernhardt, Günther, Buschauer, Armin und König, Burkhard (2011) Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). Bioorganic & Medicinal Chemistry Letters 21 (12), S. 3654-3657. Volltext nicht vorhanden.

Weiss, Stefan, Bernhardt, Günther, Buschauer, Armin und König, Burkhard (2011) Synthesis and characterization of DMAP-Modified NPY Y1 receptor antagonists as acyl-transfer catalysts. Collection of Czechoslovak chemical communications 76 (6), 763 -780. Volltext nicht vorhanden.

Ghorai, Prasanta, Kraus, Anja, Birnkammer, Tobias, Geyer, Roland, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd und Buschauer, Armin (2010) Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity. Bioorganic & Medicinal Chemistry Letters 20 (10), S. 3173-3176. Volltext nicht vorhanden.

Keller, Max, Teng, Shangjun, Bernhardt, Günther und Buschauer, Armin (2009) Bivalent argininamide-type neuropeptide Y Y1 antagonists do not support the hypothesis of receptor dimerisation. ChemMedChem 4 (10), S. 1733-1745. Volltext nicht vorhanden.

Kraus, Anja, Ghorai, Prasanta, Birnkammer, Tobias, Schnell, David, Elz, Sigurd, Seifert, Roland, Dove, Stefan, Bernhardt, Günther und Buschauer, Armin (2009) N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists. ChemMedChem 4 (2), S. 232-240. Volltext nicht vorhanden.

Igel, Patrick, Schnell, David, Bernhardt, Günther, Seifert, Roland und Buschauer, Armin (2009) Tritium-labeled N1-[3-(1H-imidazol-4-yl)propyl]-N2-propionylguanidine ([3H]UR-PI294), a high affinity histamine H3 and H4 receptor radioligand. ChemMedChem 4 (2), S. 225-231. Volltext nicht vorhanden.

Kühnle, Matthias, Egger, Michael, Müller, Christine, Mahringer, Anne, Bernhardt, Günther, Fricker, Gert, König, Burkhard und Buschauer, Armin (2009) Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. Journal of Medicinal Chemistry 52 (4), S. 1190-1197. Volltext nicht vorhanden.

Keller, Max, Pop, Nathalie, Hutzler, Christoph, Beck-Sickinger, Annette G., Bernhardt, Günther und Buschauer, Armin (2008) Guanidine - acylguanidine bioisosteric approach in the design of radioligands: Synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist. Journal of Medicinal Chemistry 51 (24), S. 8168-8172. Volltext nicht vorhanden.

Ghorai, Prasanta, Kraus, Anja, Keller, Max, Götte, Carsten, Igel, Patrick, Schneider, Erich, Schnell, David, Bernhardt, Günther, Dove, Stefan, Zabel, Manfred, Elz, Sigurd, Seifert, Roland und Buschauer, Armin (2008) Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists. Journal of Medicinal Chemistry 51 (22), S. 7193-7204. Volltext nicht vorhanden.

Weiss, Stefan, Keller, Max, Bernhardt, Günther, Buschauer, Armin und König, Burkhard (2008) Modular synthesis of non-peptidic bivalent NPY Y(1) receptor antagonists. Bioorganic & Medicinal Chemistry 16 (22), S. 9858-9866. Volltext nicht vorhanden.

Kutta, Roger J., Hofinger, Edith S. A., Preuss, Hendrik, Bernhardt, Günther und Dick, Bernhard (2008) Blue-light induced interaction of LOV domains from Chlamydomonas reinhardtii. Chembiochem : a European journal of chemical biology 9 (12), S. 1931-1938. Volltext nicht vorhanden.

Hubensack, Martina, Müller, Christine, Höcherl, Höcherl, Fellner, Stephan, Spruss, Thilo, Bernhardt, Günther und Buschauer, Armin (2008) Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice. Journal of Cancer Research and Clinical Oncology 134 (5), S. 597-607. Zugang zum Volltext eingeschränkt.

Hofinger, Edith S. A., Hoechstetter, Julia, Oettl, Martin, Bernhardt, Günther und Buschauer, Armin (2008) Isoenzyme-specific differences in the degradation of hyaluronic acid by mammalian-type hyaluronidases. Glycoconjugate Journal 25 (2), S. 101-109. Volltext nicht vorhanden.

Dai, Jisen, Jian, Jinlong, Bosland, Maarten, Frenkel, Krystyna, Bernhardt, Günther und Huang, Xi (2008) Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status. Breast (Edinburgh, Scotland) 17 (2), S. 172-179. Volltext nicht vorhanden.

Bernhardt, Günther, Biersack, Bernhard, Bollwein, Susanne, Schobert, Rainer und Zoldakova, Miroslava (2008) Terpene conjugates of diaminedichloridoplatinum(II) complexes: antiproliferative effects in HL-60 leukemia, 518A2 melanoma, and HT-29 colon cancer cells. Chemistry & biodiversity 5 (8), S. 1645-1659. Volltext nicht vorhanden.

Brennauer, Albert, Keller, Max, Freund, Matthias, Bernhardt, Günther und Buschauer, Armin (2007) Decomposition of 1-(w-aminoalkanoyl)guanidines under alkaline conditions. Tetrahedron Letters 48 (39), S. 6996-6999. Volltext nicht vorhanden.

Ziemek, Ralf, Schneider, Erich, Kraus, Anja, Cabrele, Chiara, Beck-Sickinger, Annette G., Bernhardt, Günther und Buschauer, Armin (2007) Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence. Journal of Receptors and Signal Transduction 27 (4), S. 217-233. Volltext nicht vorhanden.

Müller, Christine, Gross, Dietmar, Sarli, Vasiliki, Gartner, Michael, Giannis, Athanassios, Bernhardt, Günther und Buschauer, Armin (2007) Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemotherapy and Pharmacology 59 (2), S. 157-164. Volltext nicht vorhanden.

Hofinger, Edith S. A., Bernhardt, Günther und Buschauer, Armin (2007) Kinetics of Hyal1 and PH-20 hyaluronidases: comparison of minimal substrates and analysis of the transglycosylation reaction. Glycobiology 17 (9), S. 963-971. Volltext nicht vorhanden.

Hofinger, Edith S. A., Spickenreither, Martin, Oschmann, Jan, Bernhardt, Günther, Rudolph, Rainer und Buschauer, Armin (2007) Recombinant human hyaluronidase Hyal-1: insect cells versus E. coli as expression system and identification of low molecular weight inhibitors. Glycobiology 17 (4), S. 444-453. Volltext nicht vorhanden.

Schobert, Rainer, Bernhardt, Günther, Biersack, Bernhard, Bollwein, Susanne, Fallahi, Magid, Grotemeier, Antje und Hammond, Geoffrey L. (2007) Steroid conjugates of dichloro(6-aminomethylnicotinate)platinum(II): effects on DNA, sex hormone binding globulin, the estrogen receptor, and various breast cancer cell lines. ChemMedChem 2 (3), S. 333-342. Volltext nicht vorhanden.

Schneider, Erich, Keller, Max, Brennauer, Albert, Hoefelschweiger, Bianca K., Gross, Dietmar, Wolfbeis, Otto S., Bernhardt, Günther und Buschauer, Armin (2007) Synthesis and Characterization of the First Fluorescent Nonpeptide NPY Y1 Receptor Antagonist. ChemBioChem 8 (16), S. 1981-1988. Zugang zum Volltext eingeschränkt.

Egger, Michael, Li, Xuqin, Müller, Christine, Bernhardt, Günther, Buschauer, Armin und König, Burkhard (2007) Tariquidar analogues: synthesis by Cu(I)-catalysed N/O–aryl coupling and inhibitory activity against the ABCB1 transporter. European Journal of Organic Chemistry 2007 (16), S. 2643-2649. Volltext nicht vorhanden.

Schneider, Erich, Mayer, Matthias, Ziemek, Ralf, Li, Liantao, Hutzler, Christoph, Bernhardt, Günther und Buschauer, Armin (2006) A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G-Protein-coupled Receptor Subtypes. ChemBioChem 7 (9), S. 1400-1409. Volltext nicht vorhanden.

Rigden, Daniel J., Botzki, Alexander, Nukui, Masatoshi, Mewbourne, R. Brandon, Lamani, Ejvis, Braun, Stephan, von Angerer, Erwin, Bernhardt, Günther, Dove, Stefan, Buschauer, Armin und Jedrzejas, Mark J. (2006) Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology 16 (8), S. 757-765. Volltext nicht vorhanden.

Ziemek, Ralf, Brennauer, Albert, Schneider, Erich, Cabrele, Chiara, Beck-Sickinger, Annette G., Bernhardt, Günther und Buschauer, Armin (2006) Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y(2) receptor ligands. European Journal of Pharmacology 551 (1-3), S. 10-8. Volltext nicht vorhanden.

Spickenreither, Martin, Braun, Stephan, Bernhardt, Günther, Dove, Stefan und Buschauer, Armin (2006) Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases. Bioorganic & Medicinal Chemistry Letters 16 (20), S. 5313-5316. Volltext nicht vorhanden.

Gross, Dietmar, Bernhardt, Günther und Buschauer, Armin (2006) Platelet-derived growth factor receptor independent proliferation of human glioblastoma cells: selective tyrosine kinase inhibitors lack antiproliferative activity. Journal of Cancer Research and Clinical Oncology 132 (9), S. 589-599. Volltext nicht vorhanden.

Xie, Sheng-Xue, Petrache, Georgiana, Schneider, Erich, Ye, Qi-Zhuang, Bernhardt, Günther, Seifert, Roland und Buschauer, Armin (2006) Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine. Bioorganic & Medicinal Chemistry Letters 16 (15), S. 3886-3890. Volltext nicht vorhanden.

Botzki, Alexander, Salmen, Sunnhild, Bernhardt, Günther, Buschauer, Armin und Dove, Stefan (2005) Structure-Based Design Of Bacterial Hyaluronan Lyase Inhibitors,. QSAR & Combinatorial Science 24 (4), S. 458-469. Volltext nicht vorhanden.

Salmen, Sunnhild, Hoechstetter, Julia, Käsbauer, Christian, Paper, Dieter H., Bernhardt, Günther und Buschauer, Armin (2005) Sulphated Oligosaccharides as Inhibitors of Hyaluronidases from Bovine Testis, Bee Venom and Streptococcus agalactiae. Planta Med. 71, S. 727-732. Volltext nicht vorhanden.

Bernhardt, Günther, Brunner, Henri, Gruber, Nick, Lottner, Christian, Pushpan, Simi K., Tsuno, Takashi und Zabel, Manfred (2004) Carboplatin derivatives with superior antitumor activity compared to the parent compound. Inorganica Chimica Acta 357 (15), S. 4452-4466. Volltext nicht vorhanden.

Dittmar, Michael, Kiourkenidis, Georgios, Horn, Markus, Bollwein, Susanne und Bernhardt, Günther (2004) Cerebral ischemia, matrix metalloproteinases, and TNF-alpha: MMP inhibitors may act not exclusively by reducing MMP activity. Stroke 35 (7), e338-e340. Volltext nicht vorhanden.

Lottner, Christian, Knuechel, Ruth, Bernhardt, Günther und Brunner, Henri (2004) Combined chemotherapeutic and photodynamic treatment on human bladder cells by hematoporphyrin-platinum(II) conjugates. Cancer letters 203 (2), S. 171-180. Volltext nicht vorhanden.

Gürtler, Ulrich, Fuchs, Peter, Stangelmayer, Achim, Bernhardt, Günther, Buschauer, Armin und Spruss, Thilo (2004) Construction and validation of a microprocessor controlled extracorporal circuit in rats for the optimization of isolated limb perfusion. Archiv der Pharmazie 33 (12), S. 672-681. Volltext nicht vorhanden.

Lottner, Christian, Knuechel, Ruth, Bernhardt, Günther und Brunner, Henri (2004) Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells. Cancer letters 215 (2), S. 167-177. Volltext nicht vorhanden.

Botzki, Alexander, Rigden, Daniel J., Braun, Stephan, Nukui, Masatoshi, Salmen, Sunnhild, Hoechstetter, Julia, Bernhardt, Günther, Dove, Stefan, Buschauer, Armin und Jedrzejas, Mark J. (2004) L-ascorbic acid-6-hexadecanoate, a potent hyaluronidase inhibitor: X-ray structure and molecular modeling of enzyme-inhibitor complexes. The Journal of Biological Chemistry 279 (44), S. 45990-45997. Volltext nicht vorhanden.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruß, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald und Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level. Archiv der Pharmazie 337 (6), S. 335-348. Volltext nicht vorhanden.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruss, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald und Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity. Archiv der Pharmazie 337 (6), S. 349-359. Volltext nicht vorhanden.

Li, Liantao, Mayer, Matthias, Schneider, Erich, Schreiber, Elvira, Bernhardt, Günther, Peng, Shiqi und Buschauer, Armin (2003) Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A. Arch Pharm (Weinheim) 336 (12), S. 585-590. Volltext nicht vorhanden.

Li, Liantao, Kracht, Julia, Peng, Shiqi, Bernhardt, Günther, Elz, Sigurd und Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H2 receptor antagonists related to potentidine,. Bioorganic & Medicinal Chemistry Letters 13 (10), 0960-894. Volltext nicht vorhanden.

Oettl, Martin, Hoechstetter, Julia, Asen, Iris, Bernhardt, Günther und Buschauer, Armin (2003) Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations. European Journal of Pharmaceutical Sciences 18 (3-4), S. 267-277. Volltext nicht vorhanden.

Bart, Karl-Christian, Bernhardt, Günther, Brunner, Henri und Lottner, Christian (2003) Preparation of novel, water-soluble porphyrin platinum amine compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases. Volltext nicht vorhanden.

Li, Liantao, Kracht, Julia, Peng, Shiqi, Bernhardt, Günther und Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine,. Bioorganic & Medicinal Chemistry Letters 13 (7), S. 1245-1248. Volltext nicht vorhanden.

Klein, Michael, Zabel, Manfred, Bernhardt, Günther und König, Burkhard (2003) Tetrahydroxy 10-membered cyclic enediynes. The Journal of organic chemistry 68 (24), S. 9379-9383. Volltext nicht vorhanden.

Vogelhuber, Werner, Spruß, Thilo, Bernhardt, Günther, Buschauer, Armin und Göpferich, Achim (2002) Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts,. International Journal of Pharmaceutics 238 (1-2), S. 111-121. Volltext nicht vorhanden.

Bernhardt, Günther, Beckenlehner, Karin, Spruss, Thilo, Schlemmer, Richard, Reile, Herta und Schönenberger, Helmut (2002) Establishment and Characterization of New Murine Breast Cancer Cell Lines. Archiv der Pharmazie 335 (2), S. 55-68. Volltext nicht vorhanden.

Bernhardt, Günther, Beckenlehner, Karin, Spruss, Thilo, Schlemmer, Richard, Reile, Herta und Schönenberger, Helmut (2002) Establishment and characterization of new murine breast cancer cell lines. Archiv der Pharmazie 335 (2-3), S. 55-68. Volltext nicht vorhanden.

Lottner, Christian, Bart, Karl-Christian, Bernhardt, Günther und Brunner, Henri (2002) Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity. Journal of medicinal chemistry 45 (10), S. 2064-2078. Volltext nicht vorhanden.

Weiss, Thomas S., Bernhardt, Günther, Buschauer, Armin, Thasler, Wolfgang E., Dolgner, Doris, Zirngibl, Hubert und Jauch, Karl-Walter (2002) Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,. International Journal of Colorectal Disease 17 (6), S. 381-387. Volltext nicht vorhanden.

Lottner, Christian, Bart, Karl-Christian, Bernhardt, Günther und Brunner, Henri (2002) Soluble tetraarylporphyrin-platinum conjugates as cytotoxic and phototoxic antitumor agents. Journal of medicinal chemistry 45 (10), S. 2079-2089. Volltext nicht vorhanden.

Fellner, Stephan, Bauer, Björn, Miller, David S., Schaffrick, Martina, Fankhänel, Martina, Spruß, Thilo, Bernhardt, Günther, Graeff, Claudia, Färber, Lothar, Gschaidmeier, Harald, Buschauer, Armin und Fricker, Gert (2002) Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. The Journal of Clinical Investigation 110 (9), S. 1309-1318.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther, Gust, Ronald und Schönenberger, Helmut (2001) 1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes--new biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties. Archiv der Pharmazie 334 (4), S. 125-137. Volltext nicht vorhanden.

Schuster, Andreas, Götte, Carsten, Bernhardt, Günther und Buschauer, Armin (2001) Chiral separation of pheniramine-like 3-phenyl-3-heteroarylpropylamines by CE and HPLC methods,. Chirality 13 (6), S. 285-293. Volltext nicht vorhanden.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther und Schönenberger, Helmut (2001) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound. Archiv der Pharmazie 334 (10), S. 309-317. Volltext nicht vorhanden.

Vogelhuber, W., Rutunno, P., Magni, E., Gazzaniga, A., Spruss, Thilo, Bernhardt, Günther, Buschauer, Armin und Goepferich, Achim (2001) Programmable biodegradable implants. Journal of Controlled Release 73 (1), S. 75-88. Volltext nicht vorhanden.

Moser, Christiane, Bernhardt, Günther, Michel, J., Schwarz, H. und Buschauer, Armin (2000) Cloning and functional expression of the hNPY Y_5 receptor in human endometrial cancer (HEC-1B) cells. Can J. Physiol. Pharmacol 78, S. 134-142. Volltext nicht vorhanden.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther und Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloro-platinum(II) act as an immune response modifier? Part III: Progressively growing MXT-M-3,2 breast cancer stimulates the proliferation of phagocytes in B6D2F1 mice. Archiv der Pharmazie 333 (12), S. 404-414. Volltext nicht vorhanden.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther und Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplat inum (II) inhibits this process. Archiv der Pharmazie 333 (2-3), S. 69-71. Volltext nicht vorhanden.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther und Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part II. Studies on the influence of [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) on the specific immune defense in MXT-M-3,2 breast cancer bearing mice. Archiv der Pharmazie 333 (12), S. 397-403. Volltext nicht vorhanden.

Buschauer, Armin, Bernhardt, Günther und Dove, Stefan (2000) NPY-Rezeptoren als Zielstrukturen für neue Arzneistoffe. Pharmazeutische Zeitung 24, S. 11-18. Volltext nicht vorhanden.

Aiglstorfer, Iris, Hendrich, Ingo, Moser, Christiane, Bernhardt, Günther, Dove, Stefan und Buschauer, Armin (2000) Structure-Activity Relationships of Neuropeptide Y Y_1 Receptor Antagonists Related to BIBP 3226,. Bioorganic & Medicinal Chemistry Letters 10 (14), S. 1597-1600. Volltext nicht vorhanden.

Meister, A., Bernhardt, Günther, Christoffel, V. und Buschauer, Armin (1999) Antispasmodic Activity of Thymus vulgaris, Extract on the Isolated Guinea-Pig Trachea: Discrimination Between Drug and Ethanol Effects. Planta Med 1999, S. 512-516. Volltext nicht vorhanden.

Moser, Christiane, Bernhardt, Günther und Buschauer, Armin (1999) Efficient Transfection of Human Endometrial Cancer (HEC-1B) Cells with FuGENE^TM 6 Transfection Reagent. biochemica 1/1999, S. 26-27. Volltext nicht vorhanden.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther und Schönenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl) ethylenediamine]dichloroplatinum(II), a compound with a specific activity on hormone-sensitive breast cancers--evidence for a diethylstilbestrol-like mode of action. Archiv der Pharmazie 332 (2), S. 59-69. Volltext nicht vorhanden.

Bernhardt, Günther, Koch, Marion, Spruss, Thilo, Gust, Ronald, Krauser, Rudolf, Schlemmer, Richard, Hollstein, Michael, Lux, Franz und Schönenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] sulfatoplatinum(II)--pharmacokinetic studies. Archiv der Pharmazie 332 (6), S. 195-200. Volltext nicht vorhanden.

Schuster, Andreas, Bernhardt, Günther, Eibler, Ernst, Buschauer, Armin und Hesselink, Willy (1998) Chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, and analogous guanidines and guanidine-N-carboxylic acid esters with HPLC and CZE. Journal of Chromatography A 793 (1), S. 77-90. Volltext nicht vorhanden.

Pillwein, Konrad, Fuiko, R., Slavc, I., Czech, T., Hawliczek, G., Bernhardt, Günther, Nirnberger, Gunther und Koller, U. (1998) Hyaluronidase additional to standard chemotherapy improves outcome for children with malignant brain tumors. Cancer Letters (Shannon, Ireland) 131 (1), S. 101-108. Volltext nicht vorhanden.

Aiglstorfer, Iris, Uffrecht, Anka, Geßele, K., Moser, Christiane, Schuster, Andreas, Merz, S., Malawska, B., Bernhardt, Günther, Dove, Stefan und Buschauer, Armin (1998) NPY Y_1 antagonists: structure-activity relationships of arginine derivatives and hybrid compounds with arpromidine-like partial structures. Regul. Pept. 75, S. 75-76. Volltext nicht vorhanden.

Muckenschnabel, I., Bernhardt, Günther, Spruß, Thilo und Buschauer, Armin (1998) Pharmacokinetics and tissue distribution of bovine testicular hyaluronidase and vinblastine in mice: an attempt to optimize the mode of adjuvant hyaluronidase administration in cancer chemotherapy. Cancer Letters 131 (1), S. 71-84. Volltext nicht vorhanden.

Muckenschnabel, Ingo, Bernhardt, Günther, Spruß, Thilo, Dietl, Barbara und Buschauer, Armin (1998) Quantitation of hyaluronidases by the Morgan-Elson reaction: comparison of the enzyme activities in the plasma of tumor patients and healthy volunteers. Cancer Letters 131, S. 13-20. Volltext nicht vorhanden.

Gust, Ronald, Schnurr, Beate, Krauser, Rudolf, Bernhardt, Günther, Koch, Marion, Schmid, Beate, Hummel, Evelyn und Schönenberger, Helmut (1998) Stability and cellular studies of [rac-1,2-bis(4-fluorophenyl)ethylenediamine][cyclobutane-1,1-dicarboxylato]platinum(II), a novel, highly active carboplatin derivative. Journal of Cancer Research and Clinical Oncology 124 (11), S. 585-597. Volltext nicht vorhanden.

Schuster, Andreas, Bollwein, Susanne, Uffrecht, Anka, Krey, Volker, Götte, Carsten, Bernhardt, Günther und Buschauer, Armin (1998) Stereochemical Investigations on Intermediates for the Synthesis of Histamine H_2 Receptor Agonists and Neuropeptide Y Y_1 Antagonists: Chiral Separation of Phenyl(pyridyl)alkanoic Acids by HPLC and CE. Sci. Pharm 66, S. 263-278. Volltext nicht vorhanden.

Muckenschnabel, I., Bernhardt, Günther, Spruß, Thilo und Buschauer, Armin (1997) A versatile HPLC method for the measurement of melphalan tailored to the optimization of hyperthermic isolated limb perfusion,. Eur. J. Pharm. Sci. 5, S. 129-137. Volltext nicht vorhanden.

Schuster, Andreas, Bernhardt, Günther und Buschauer, Armin (1997) Determination of the arpromidine-type histamine H2-receptor agonist N1-[3-(3,4-difluoro­phe­nyl)-3-(2-pyridyl)propyl]-N2-[3-(1H-imidazol-4-yl)propyl]guanidine and corresponding N3-alkoxycarbonylguanidines by HPLC and CE. Eur. J. Pharm. Sci. 5, S. 79-88. Volltext nicht vorhanden.

Weiss, Thomas, Bernhardt, Günther, Buschauer, Armin, Jauch, Karl-Walter und Zirngibl, Hubert (1997) High-resolution RP HPLC analysis of polyamines and their monoacetyl conjugates by fluorescence detection after derivatization with N-hydroxy-succinimidyl 6-quinolinyl carbamate. Anal. Biochem 247, S. 294-304. Volltext nicht vorhanden.

Müller, Manfred, Knieps, Sebastian, Geßele, Karin, Dove, Stefan, Bernhardt, Günther und Buschauer, Armin (1997) Synthesis and neuropeptide Y Y1 receptor antagonistic activity of N,N-disubstituted w -guanidino- and w -aminoalkanoic acid amides. Arch. Pharm. - Pharm. Med. Chem. (Weinheim) 330, S. 333-342. Volltext nicht vorhanden.

Spruss, Thilo und Bernhardt, Günther (1996) Chemosensitivity of malignant melanoma models: long-term complete remission after regional hyaluronidase/vinblastine therapy. In: Arnold, Wolfgang, (ed.) Immunodeficient Animals: Models for Cancer Research. Contributions to Oncology, 51. , S. 145-150. Volltext nicht vorhanden.

Lux, Franz, Hollstein, Michael, Reile, Herta, Bernhardt, Günther und Schönenberger, Helmut (1996) Discrepancy between cytotoxicity, platinum accumulation, and DNA platination in MCF-7 breast cancer cells treated with diaqua(1,2-diphenylethylenediamine) platinum(II) sulfates and cisplatin. Biological Trace Element Research 53 (1-3), S. 113-128. Volltext nicht vorhanden.

Muckenschnabel, Ingo, Bernhardt, Günther, Spruß, Thilo und Buschauer, Armin (1996) Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice. Cancer Chemother. Pharmacol 38, S. 88-94. Volltext nicht vorhanden.

Knieps, Sebastian, Dove, Stefan, Michel, Martin C., Rottmeier, Karin, Wernet, W., Bernhardt, Günther und Buschauer, Armin (1996) w -Phenyl-w -(2-pyridyl)alkyl-substituted bisguanidines are moderate neuropeptide Y antagonists. Pharm. Pharmacol. Lett. 6, S. 27-30. Volltext nicht vorhanden.

Gust, Ronald, Bernhardt, Günther, Spruss, Thilo, Krauser, Rudolf, Koch, Marion, Schönenberger, Helmut, Bauer, Kurt H., Schertl, Sabine und Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the "third generation platinum complex" [(+/-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie 328 (9), S. 645-653. Volltext nicht vorhanden.

Gust, Ronald, Bernhardt, Günther, Spruss, Thilo, Krauser, Rudolf, Koch, Marion, Schönenberger, Helmut, Bauer, Kurt-Heinz, Schertl, Sabine und Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the \"third generation platinum complex\" [(+-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie (Weinheim, Germany) 328 (9), S. 645-653. Volltext nicht vorhanden.

Spruß, Thilo, Bernhardt, Günther, Schönenberger, Helmut und Schiess, Wilfried (1995) Hyaluronidase significantly enhances the efficacy of regional vinblastine chemotherapy of malignant melanoma. Journal of cancer research and clinical oncology 121 (4), S. 193-202. Volltext nicht vorhanden.

Beck, E., Hofmann, M., Bernhardt, Günther, Jäger, W., Wildt, L. und Lang, N. (1994) In vitro activity of immunoconjugates between cisplatin and an anti-CA125 monoclonal antibody on ovarian cancer cell lines. Cell biophysics 24-25, S. 163-173. Volltext nicht vorhanden.

Spruß, Thilo, Bernhardt, Günther, Schönenberger, Helmut und Engel, Jürgen (1993) Antitumour activity of miltefosine alone and after combination with platinum complexes on MXT mouse mammary carcinoma models. Journal of cancer research and clinical oncology 119 (3), S. 142-149.

Kritzenberger, J, Bernhardt, Günther, Gust, Ronald, Pistor, Petra, Schönenberger, Helmut und Yersin, Hartmut. (1993) Dichlorobis(cycloalkylamine)platinum(II) complexes. Structure activity relationship on the human MDA-MB-231 breast cancer cell line. Monatshefte fuer Chemie 124 (5), S. 587-604.

Bernhardt, Günther (1993) Entwicklung und Anwendung moderner Testverfahren zur Auffindung und Optimierung der Antitumorwirkung neuartiger Diphenylethylendiaminplatin(II)-Komplexe. Habilitation, Regensburg, Universität.

Hollstein, Michael, Lux, Franz, Reile, Herta, Bernhardt, Günther und Schönenberger, Helmut (1993) NAA of platinated DNA after treatment of cancer cells with new platinum complexes. Volltext nicht vorhanden.

Meyer, Thomas, Goehl, Jonas, Hohenberger, Werner, Christl, Claudia, Bernhardt, Günther, Spruss, Thilo und Schönenberger, Helmut (1993) The choice of cytostatic in hyperthermic isolated limb perfusion. Chemosensitivity testing on five human melanoma cell lines. Chirurgisches Forum fuer Experimentelle und Klinische Forschung, S. 89-94. Volltext nicht vorhanden.

Reile, Herta, Bernhardt, Günther, Koch, Marion, Schönenberger, Helmut, Hollstein, Michael und Lux, Franz (1992) Chemosensitivity of human MCF-7 breast cancer cells to diastereoisomeric diaqua(1,2-diphenylethylenediamine) platinum(II) sulfates and specific platinum accumulation. Cancer chemotherapy and pharmacology 30 (2), S. 113-122.

Bernhardt, Günther, Müller, Richard, Gust, Ronald, Reile, Herta, Keller, Christoph, Spruss, Thilo und Schönenberger, Helmut (1992) Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3. Archiv der Pharmazie 325 (2), S. 93-99.

Grimm, Daniela, Hofstädter, Ferdinand, Bauer, Johann, Spruss, Thilo, Steinbach, Pia, Bernhardt, Günther und Menze, Rita (1992) Establishment and characterization of a human papillary thyroid carcinoma cell line with oxyphilic differentiation (ONCO-DG 1). Virchows Archiv. B, Cell pathology including molecular pathology 62 (2), S. 97-104.

Beckenlehner, Karin, Bannke, Silke, Spruss, Thilo, Bernhardt, Günther, Schönenberger, Helmut und Schiess, Wilfried (1992) Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo. Journal of cancer research and clinical oncology 118 (8), S. 591-596.

Bernhardt, Günther, Reile, Herta, Birnböck, Herbert, Spruss, Thilo und Schönenberger, Helmut (1992) Standardized kinetic microassay to quantify differential chemosensitivity on the basis of proliferative activity. Journal of cancer research and clinical oncology 118 (1), S. 35-43.

Bernhardt, Günther, Gust, Ronald, Reile, Herta, vom Orde, Hans Dieter, Müller, Richard, Keller, Christoph, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas, Mannschreck, Albrecht, Range, Klaus-Jürgen und Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. II. Synthesis and preliminary testing of the enantiomeric complexes. Journal of cancer research and clinical oncology 118 (3), S. 201-208.

Bernhardt, Günther, Gust, Ronald, Reile, Herta, vom Orde, Hans Dieter, Müller, Richard, Keller, Christoph, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas, Mannschreck, Albrecht, Range, Klaus Jürgen und Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. III. Detailed evaluation of the antitumor activity of the enantiomeric complexes on the human NIH:OVCAR-3 ovarian cancer cell line. Journal of cancer research and clinical oncology 118 (3), S. 209-215.

Bernhardt, Günther, Reile, Herta, Spruss, Thilo, Koch, Marion, Gust, Ronald, Schönenberger, Helmut, Hollstein, Michael, Lux, Franz und Engel, Jürgen (1991) D-17446. Drugs of the Future 16 (10), S. 899-903.

Spruß, Thilo, Bernhardt, Günther, Schickaneder, Edith und Schönenberger, Helmut (1991) Different response of murine and human mammary tumour models to a series of diastereoisomeric [1,2-bis(difluorophenyl) ethylenediamine]dichloroplatinum(II) complexes. Journal of cancer research and clinical oncology 117 (5), S. 435-443. Volltext nicht vorhanden.

Bernhardt, Günther, Spruss, Thilo und Schönenberger, Helmut (1991) Einsatz menschlicher Tumorzellkulturen als Testmodelle bei der Entwicklung von Wirkstoffen für die Krebstherapie. Forum für interdisziplinäre Forschung : FIF 4, S. 24-28.

Altman, Janina, Castrillo, Thais, Beck, Wolfgang, Bernhardt, Günther und Schönenberger, Helmut (1991) Metal complexes with biologically important ligands. 62. Platinum(II) complexes of 3-(2-aminoethoxy)estrone and -estradiol. Inorganic Chemistry 30 (21), S. 4085-4088.

Reile, Herta, Spruß, Thilo, Bernhardt, Günther, Müller, Richard, Gust, Ronald und Schönenberger, Helmut (1991) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part IV: Biological evaluation--in vivo studies on the P 388 leukemia. Archiv der Pharmazie 324 (7), S. 405-409.

Reile, Herta, Birnböck, Herbert, Bernhardt, Günther, Spruß, Thilo und Schönenberger, Helmut (1990) Computerized determination of growth kinetic curves and doubling times from cells in microculture. Analytical biochemistry 187 (2), S. 262-267.

Reile, Herta, Spruß, Thilo, Müller, Richard, Gust, Ronald, Bernhardt, Günther, Schönenberger, Helmut und Engel, Jürgen (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes, III: Evaluation of the mammary tumor inhibiting properties. Archiv der Pharmazie 323 (5), S. 301-306.

Reile, Herta, Müller, Richard, Gust, Ronald, Laske, Reiner, Krischke, Walter, Bernhardt, Günther, Spruss, Thilo, Jennerwein, Margaretha, Engel, Jürgen und Seeber, Siegfried (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part II: Biological evaluation-in vitro studies on the P 388 D1 leukemia cell line. Archiv der Pharmazie 323 (3), S. 133-140.

vom Orde, Hans Dieter, Reile, Herta, Müller, Richard, Gust, Ronald, Bernhardt, Günther, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas und Mannschreck, Albrecht (1990) Tumor-inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. V. Synthesis and evaluation of enantiomeric [1,2-bis-(4-fluorophenyl)ethylenediamine]dichloroplatinum(II) complexes. Journal of cancer research and clinical oncology 116 (5), S. 434-438.

Müller, Richard, Gust, Ronald, Bernhardt, Günther, Keller, Christoph, Schönenberger, Helmut, Seeber, Siegfried, Osieka, Reinhardt, Eastman, Alan und Jennerwein, Margaretha (1990) [DL-1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. Journal of cancer research and clinical oncology 116 (3), S. 237-244.

Mueller, Richard, Gust, Ronald, Jennerwein, Margaretha, Reile, Herta, Laske, Reiner, Krischke, Walter, Bernhardt, Günther, Spruss, Thilo, Engel, Juergen und Schönenberger, Helmut (1989) Tumor inhibiting [1,2-bis(fluorophenylethylenediamine]platinum(II) complexes. Part I. Synthesis. European Journal of Medicinal Chemistry 24 (4), S. 341-348.

Bernhardt, Günther, Disteche, A., Jaenicke, Rainer, Koch, B., Luedemann, Hans-Dietrich und Stetter, Karl Otto (1988) EFFECT OF CARBON-DIOXIDE AND HYDROSTATIC-PRESSURE ON THE PH OF CULTURE MEDIA AND THE GROWTH OF METHANOGENS AT ELEVATED-TEMPERATURE. Applied Microbiology and Biotechnology 28 (2), S. 176-181.

Bernhardt, Günther, Jaenicke, Rainer, Lüdemann, Hans-Dietrich, König, Helmut und Stetter, Karl Otto (1988) High Pressure Enhances the Growth Rate of the Thermophilic Archaebacterium Methanococcus thermolithotrophicus without Extending Its Temperature Range. Applied and environmental microbiology 54 (5), S. 1258-1261.

Jaenicke, Rainer, Bernhardt, Günther, Lüdemann, Hans-Dietrich und Stetter, Karl Otto (1988) Pressure-Induced Alterations in the Protein Pattern of the Thermophilic Archaebacterium Methanococcus thermolithotrophicus. Applied and environmental microbiology 54 (10), S. 2375-2380.

Bernhardt, Günther, Jaenicke, Rainer und Lüdemann, Hans-Dietrich (1987) High-Pressure Equipment for Growing Methanogenic Microorganisms on Gaseous Substrates at High Temperature. Applied and environmental microbiology 53 (8), S. 1876-1879.

Bernhardt, Günther (1986) Hochdruckuntersuchungen an thermophilen Bakterien. Dissertation, Regensburg, Universität.

Luedemann, Hans-Dietrich, Bernhardt, Günther, Jaenicke, Rainer, Koenig, Helmut und Stetter, Karl Otto (1984) Biomolecules are unstable under "black smoker" conditions. Naturwissenschaften 71 (11), S. 583-586. Volltext nicht vorhanden.

Bernhardt, Günther, Rudolph, Rainer und Jaenicke, Rainer (1981) Reassociation of lactic dehydrogenase from pig heart studied by cross-linking with glutaraldehyde. Zeitschrift fuer Naturforschung, C Journal of Biosciences 36C (9-10), S. 772-777. Volltext nicht vorhanden.

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