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Article

Baumeister, Paul and Erdmann, Daniela and Biselli, Sabrina and Kagermeier, Nicole and Elz, Sigurd and Bernhardt, Günther and Buschauer, Armin (2014) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem. (In Press)

Pollinger, Klaus and Hennig, Robert and Bauer, Stefanie and Breunig, Miriam and Tessmar, Joerg and Buschauer, Armin and Witzgall, Ralph and Göpferich, Achim (2014) Biodistribution of quantum dots in the kidney after intravenous injection. Journal of Nanoscience and Nanotechnology 14 (5), pp. 3313-3319.

Cuboni, Serena and Devigny, Christian and Hoogeland, Bastiaan and Strasser, Andrea and Pomplun, Sebastian and Hauger, Barbara and Höfner, Georg and Wanner, Klaus and Eder, Matthias and Buschauer, Armin and Holsboer, Florian and Hausch, Felix (2014) Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2. Journal of Medicinal Chemistry. (In Press)

Wifling, David and Löffel, Karolin and Nordemann, Uwe and Strasser, Andrea and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Buschauer, Armin (2014) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology. (In Press)

Werner, Kristin and Neumann, Detlef and Buschauer, Armin and Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics. (In Press)

Geyer, Roland and Kaske, Melanie and Baumeister, Paul and Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), pp. 77-88.

Geyer, Roland and Igel, Patrick and Kaske, Melanie and Elz, Sigurd and Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), pp. 72-81.

Sadek, Bassem and Alisch, Rudi and Buschauer, Armin and Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), pp. 14186-14202.

Dove, Stefan and Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), pp. 3-9.

Keller, Max and Kaske, Melanie and Holzammer, Tobias and Bernhardt, Günther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), pp. 6303-6322.

Berlicki, Lukasz and Kaske, Melanie and Gutierrez-Abad, Raquel and Bernhardt, Günther and Illa, Ona and Ortuño, Rosa and Cabrele, Chiara and Buschauer, Armin and Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), pp. 8422-8431.

Nordemann, Uwe and Wifling, David and Schnell, David and Bernhardt, Günther and Stark, Holger and Seifert, Roland and Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie and Ochoa Puentes, Cristian and Sun, Qiu and Bause, Manuel and Bernhardt, Günther and König, Burkhard and Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), pp. 1773-1778.

Brunskole Hummel, Irena and Kälble, Solveig and Burhenne, Heike and Reinartz, Michael T. and Schwede, Frank and Buschauer, Armin and Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Ochoa-Puentes, Cristian and Bauer, Stefanie and Kühnle, Matthias and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), pp. 393-396.

Pluym, Nikola and Baumeister, Paul and Keller, Max and Bernhardt, Günther and Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), pp. 587-593.

Seifert, Roland and Strasser, Andrea and Schneider, Erich H. and Neumann, Detlef and Dove, Stefan and Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), pp. 33-58.

Strasser, Andrea and Wittmann, Hans-Joachim and Buschauer, Armin and Schneider, Erich H. and Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), pp. 13-32.

Bodensteiner, Julian and Baumeister, Paul and Geyer, Roland and Buschauer, Armin and Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), pp. 4040-55.

Memminger, Martin and Keller, Max and Lopuch, Miroslaw and Pop, Nathalie and Bernhardt, Günther and von Angerer, Erwin and Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Löber, Stefan and Hübner, Harald and Buschauer, Armin and Sanna, Fabrizio and Argiolas, Antonio and Melis, Maria Rosaria and Gmeiner, Peter (2012) Novel azulene derivatives for the treatment of erectile dysfunction. Bioorganic & medicinal chemistry letters 22 (23), pp. 7151-7154.

Rothenhöfer, Martin and Scherübl, Rosmarie and Bernhardt, Günther and Heilmann, Jörg and Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, pp. 169-77.

Reher, Till M. and Neumann, Detlef and Buschauer, Armin and Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), pp. 192-203.

Birnkammer, Tobias and Spickenreither, Anja and Brunskole, Irena and Lopuch, Miroslaw and Kagermeier, Nicole and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), pp. 1147-1160.

Grundmann, Marco and Rothenhöfer, M. and Bernhardt, Günther and Buschauer, Armin and Matysik, Frank-Michael (2012) Fast counter-electroosmotic capillary electrophoresis-time-of-flight mass spectrometry of hyaluronan oligosaccharides. Analytical and Bioanalytical Chemistry : Anal. Bioanal. Chem. 402, pp. 2617-2623.

Bernat, Viachaslau and Heinrich, Markus and Baumeister, Paul and Buschauer, Armin and Tschammer, Nuska (2012) Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. ChemMedChem 7 (8), pp. 1481-1489.

Brunskole, Irena and Strasser, Andrea and Seifert, Roland and Buschauer, Armin (2011) Role of the second and third extracellular loops of the histamine H4 receptor in receptor activation. Naunyn-Schmiedeberg's Archives of Pharmacology 384 (3), pp. 301-317.

Braun, Stephan and Botzki, Alexander and Salmen, Sunnhild and Textor, Christian and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (2011) Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase. European Journal of Medicinal Chemistry 46 (9), pp. 4419-4429.

Pluym, Nikola and Brennauer, Albert and Keller, Max and Ziemek, Ralf and Pop, Nathalie and Bernhardt, Günther and Buschauer, Armin (2011) Application of the guanidine – acylguanidine bioisosteric approach to argininamide-type NPY Y2 receptor antagonists. ChemMedChem 6 (9), pp. 1727-1738.

Geyer, Roland and Buschauer, Armin (2011) Synthesis and histamine H3 and H4 receptor activity of conformationally restricted cyanoguanidines related to UR-PI376. Archiv der Pharmazie 344 (12), pp. 775-785.

Keller, Max and Bernhardt, Günther and Buschauer, Armin (2011) [3H]UR-MK136 - a highly potent and selective radioligand for neuropeptide Y Y1 receptors. ChemMedChem 6 (9), pp. 1566-1571.

Pop, Nathalie and Igel, Patrick and Brennauer, Albert and Cabrele, Chiara and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2011) Functional reconstitution of human neuropeptide Y (NPY) Y2 and Y4 receptors in Sf9 insect cells. Journal of Receptors and Signal Transduction 31 (4), pp. 271-285.

Keller, Max and Erdmann, Daniela and Teng, Shangjun and Pop, Nathalie and Pluym, Nikola and Bernhardt, Günther and Buschauer, Armin (2011) Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools. Bioorganic & Medicinal Chemistry 19 (9), pp. 2859-2878.

Schnell, David and Brunskole, Irena and Ladova, Katerina and Schneider, Erich H. and Igel, Patrick and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2011) Expression and functional properties of canine, rat and murine histamine H4-receptors in Sf9 insect cells. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (5), pp. 457-470.

Seifert, Roland and Schneider, Erich H. and Dove, Stefan and Brunskole, Irena and Neumann, Detlef and Strasser, Andrea and Buschauer, Armin (2011) Paradoxical stimulatory effects of the “standard” histamine H4-receptor antagonist JNJ7777120: The H4-receptor joins the club of 7TM receptors exhibiting functional selectivity. Molecular Pharmacology 79 (4), pp. 631-638.

Ochoa Puentes, Cristian and Höcherl, Peter and Kühnle, Matthias and Bauer, Stefanie and Kürger, Kira and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2011) Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). Bioorganic & Medicinal Chemistry Letters 21 (12), pp. 3654-3657.

Weiss, Stefan and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2011) Synthesis and characterization of DMAP-Modified NPY Y1 receptor antagonists as acyl-transfer catalysts. Collection of Czechoslovak chemical communications 76 (6), 763 -780.

Igel, Patrick and Dove, Stefan and Buschauer, Armin (2010) Histamine H4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199.

Hild, Wolfgang and Pollinger, Klaus and Caporale, Andrea and Cabrele, Chiara and Keller, Max and Pluym, Nicola and Buschauer, Armin and Rachel, Reinhard and Tessmar, Joerg and Breunig, Miriam and Goepferich, Achim (2010) G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake. Proceedings of the National Academy of Sciences USA: PNAS 107 (23), pp. 10667-10672.

Ghorai, Prasanta and Kraus, Anja and Birnkammer, Tobias and Geyer, Roland and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2010) Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity. Bioorganic & Medicinal Chemistry Letters 20 (10), pp. 3173-3176.

Kleinmaier, R. and Igel, P. and Keller, M. and Buschauer, Armin and Gschwind, R. M. (2010) Conformations, Conformational Preferences, and Conformational Exchange of N'-Substituted N-Acylguanidines: Intermolecular Interactions Hold the Key. J. Am. Chem. Soc. 132 (32), pp. 11223-11233.

Weiss, Stefan and Keller, Max and Bernhardt, G. and Buschauer, Armin and König, Burkhard (2010) N(G)-Acyl-argininamides as NPY Y (1) receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity. Bioorganic & Medicinal Chemistry (18), pp. 6292-6304.

Igel, Patrick and Geyer, Roland and Straßer, Andrea and Dove, Stefan and Seifert, Roland and Buschauer, Armin (2009) Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H(4) receptor agonists. Journal of Medicinal Chemistry 52 (20), pp. 6297-6313.

Keller, Max and Teng, Shangjun and Bernhardt, Günther and Buschauer, Armin (2009) Bivalent argininamide-type neuropeptide Y Y1 antagonists do not support the hypothesis of receptor dimerisation. ChemMedChem 4 (10), pp. 1733-1745.

Igel, Patrick and Schneider, Erich and Schnell, David and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2009) N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. Journal of Medicinal Chemistry 52 (8), pp. 2623-2627.

Kraus, Anja and Ghorai, Prasanta and Birnkammer, Tobias and Schnell, David and Elz, Sigurd and Seifert, Roland and Dove, Stefan and Bernhardt, Günther and Buschauer, Armin (2009) N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists. ChemMedChem 4 (2), pp. 232-240.

Igel, Patrick and Schnell, David and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2009) Tritium-labeled N1-[3-(1H-imidazol-4-yl)propyl]-N2-propionylguanidine ([3H]UR-PI294), a high affinity histamine H3 and H4 receptor radioligand. ChemMedChem 4 (2), pp. 225-231.

Kühnle, Matthias and Egger, Michael and Müller, Christine and Mahringer, Anne and Bernhardt, Günther and Fricker, Gert and König, Burkhard and Buschauer, Armin (2009) Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. Journal of Medicinal Chemistry 52 (4), pp. 1190-1197.

Keller, Max and Pop, Nathalie and Hutzler, Christoph and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2008) Guanidine - acylguanidine bioisosteric approach in the design of radioligands: Synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist. Journal of Medicinal Chemistry 51 (24), pp. 8168-8172.

Ghorai, Prasanta and Kraus, Anja and Keller, Max and Götte, Carsten and Igel, Patrick and Schneider, Erich and Schnell, David and Bernhardt, Günther and Dove, Stefan and Zabel, Manfred and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2008) Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists. Journal of Medicinal Chemistry 51 (22), pp. 7193-7204.

Weiss, Stefan and Keller, Max and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2008) Modular synthesis of non-peptidic bivalent NPY Y(1) receptor antagonists. Bioorganic & Medicinal Chemistry 16 (22), pp. 9858-9866.

Hubensack, Martina and Müller, Christine and Höcherl, Höcherl and Fellner, Stephan and Spruss, Thilo and Bernhardt, Günther and Buschauer, Armin (2008) Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice. Journal of Cancer Research and Clinical Oncology 134 (5), pp. 597-607.

Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2008) Frontiers in medicinal chemistry in Regensburg. ChemMedChem 3 (8), pp. 1181-1184.

Hofinger, Edith S. A. and Hoechstetter, Julia and Oettl, Martin and Bernhardt, Günther and Buschauer, Armin (2008) Isoenzyme-specific differences in the degradation of hyaluronic acid by mammalian-type hyaluronidases. Glycoconjugate Journal 25 (2), pp. 101-109.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Constitutive Activity and Ligand Selectivity of Human,
Guinea Pig, Rat, and Canine Histamine H₂ Receptors.
Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 983-995.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Mutations of Cys-17 and Ala-271 in the Human Histamine H₂
Receptor Determine the Species Selectivity of Guanidine-Type Agonists and Increase Constitutive Activity.
Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 975-982.

Brennauer, Albert and Keller, Max and Freund, Matthias and Bernhardt, Günther and Buschauer, Armin (2007) Decomposition of 1-(w-aminoalkanoyl)guanidines under alkaline conditions. Tetrahedron Letters 48 (39), pp. 6996-6999.

Ziemek, Ralf and Schneider, Erich and Kraus, Anja and Cabrele, Chiara and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2007) Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence. Journal of Receptors and Signal Transduction 27 (4), pp. 217-233.

Xie, Sheng-Xue and Schalkhausser, Fabian and Ye, Qi-Zhuang and Seifert, Roland and Buschauer, Armin (2007) Effects of Impromidine- and Arpromidine-Derived Guanidines on Recombinant Human and Guinea Pig Histamine H₁ and H₂ Receptors. Archiv der Pharmazie 340 (1), pp. 9-16.

Müller, Christine and Gross, Dietmar and Sarli, Vasiliki and Gartner, Michael and Giannis, Athanassios and Bernhardt, Günther and Buschauer, Armin (2007) Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemotherapy and Pharmacology 59 (2), pp. 157-164.

Hofinger, Edith S. A. and Bernhardt, Günther and Buschauer, Armin (2007) Kinetics of Hyal1 and PH-20 hyaluronidases: comparison of minimal substrates and analysis of the transglycosylation reaction. Glycobiology 17 (9), pp. 963-971.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), pp. 253-264.

Hofinger, Edith S. A. and Spickenreither, Martin and Oschmann, Jan and Bernhardt, Günther and Rudolph, Rainer and Buschauer, Armin (2007) Recombinant human hyaluronidase Hyal-1: insect cells versus E. coli as expression system and identification of low molecular weight inhibitors. Glycobiology 17 (4), pp. 444-453.

Schneider, Erich and Keller, Max and Brennauer, Albert and Hoefelschweiger, Bianca K. and Gross, Dietmar and Wolfbeis, Otto S. and Bernhardt, Günther and Buschauer, Armin (2007) Synthesis and Characterization of the First Fluorescent Nonpeptide NPY Y1 Receptor Antagonist. ChemBioChem 8 (16), pp. 1981-1988.

Egger, Michael and Li, Xuqin and Müller, Christine and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2007) Tariquidar analogues: synthesis by Cu(I)-catalysed N/O–aryl coupling and inhibitory activity against the ABCB1 transporter. European Journal of Organic Chemistry 2007 (16), pp. 2643-2649.

Xie, Sheng-Xue and Kraus, Anja and Ghorai, Prasanta and Ye, Qi-Zhuang and Elz, Sigurd and Buschauer, Armin and Seifert, Roland (2006) N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors.
Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268.

Wabnitz, Tobias C. and Rizzo, Simona and Götte, Carsten and Buschauer, Armin and Benincori, Tiziana and Reiser, Oliver (2006) Enantioselective hydrogenation of diaryl-substituted a,b-unsaturated nitriles. Tetrahedron Letters 47 (22), pp. 3733-3736.

Xie, Sheng-Xue and Ghorai, Prasanta and Ye, Qi-Zhuang and Buschauer, Armin and Seifert, Roland (2006) Probing Ligand-Specific Histamine H1- and H2-Receptor
Conformations with NG-Acylated Imidazolylpropylguanidines.
The Journal of Pharmacology and Experimental Therapeutics 317 (1), pp. 139-146.

Schneider, Erich and Mayer, Matthias and Ziemek, Ralf and Li, Liantao and Hutzler, Christoph and Bernhardt, Günther and Buschauer, Armin (2006) A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G-Protein-coupled Receptor Subtypes. ChemBioChem 7 (9), pp. 1400-1409.

Rigden, Daniel J. and Botzki, Alexander and Nukui, Masatoshi and Mewbourne, R. Brandon and Lamani, Ejvis and Braun, Stephan and von Angerer, Erwin and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin and Jedrzejas, Mark J. (2006) Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology 16 (8), pp. 757-765.

Ziemek, Ralf and Brennauer, Albert and Schneider, Erich and Cabrele, Chiara and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2006) Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y(2) receptor ligands. European Journal of Pharmacology 551 (1-3), pp. 10-8.

Spickenreither, Martin and Braun, Stephan and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (2006) Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases. Bioorganic & Medicinal Chemistry Letters 16 (20), pp. 5313-5316.

Gross, Dietmar and Bernhardt, Günther and Buschauer, Armin (2006) Platelet-derived growth factor receptor independent proliferation of human glioblastoma cells: selective tyrosine kinase inhibitors lack antiproliferative activity. Journal of Cancer Research and Clinical Oncology 132 (9), pp. 589-599.

Xie, Sheng-Xue and Petrache, Georgiana and Schneider, Erich and Ye, Qi-Zhuang and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2006) Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine. Bioorganic & Medicinal Chemistry Letters 16 (15), pp. 3886-3890.

Botzki, Alexander and Salmen, Sunnhild and Bernhardt, Günther and Buschauer, Armin and Dove, Stefan (2005) Structure-Based Design Of Bacterial Hyaluronan Lyase Inhibitors,. QSAR & Combinatorial Science 24 (4), pp. 458-469.

Salmen, Sunnhild and Hoechstetter, Julia and Käsbauer, Christian and Paper, Dieter H. and Bernhardt, Günther and Buschauer, Armin (2005) Sulphated Oligosaccharides as Inhibitors of Hyaluronidases from Bovine Testis, Bee Venom and Streptococcus agalactiae. Planta Med. 71, pp. 727-732.

Kießling, Stephan and Müller-Newen, Gerhard and Leeb, Sandra N. and Hausmann, Martin and Rath, Heiko C. and Strater, Jörn and Spottl, Tanja and Schlottmann, Klaus and Grossmann, Johannes and Montero-Julian, F. A. and Schölmerich, Jürgen and Andus, Tilo and Buschauer, Armin and Heinrich, Peter C. and Rogler, Gerhard (2004) Functional Expression of the Interleukin-11 Receptor α-Chain and Evidence of Antiapoptotic Effects in Human Colonic Epithelial Cells. The Journal of Biological Chemistry 279 (11), pp. 10304-10315.

Gürtler, Ulrich and Fuchs, Peter and Stangelmayer, Achim and Bernhardt, Günther and Buschauer, Armin and Spruss, Thilo (2004) Construction and validation of a microprocessor controlled extracorporal circuit in rats for the optimization of isolated limb perfusion. Archiv der Pharmazie 33 (12), pp. 672-681.

Botzki, Alexander and Rigden, Daniel J. and Braun, Stephan and Nukui, Masatoshi and Salmen, Sunnhild and Hoechstetter, Julia and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin and Jedrzejas, Mark J. (2004) L-ascorbic acid-6-hexadecanoate, a potent hyaluronidase inhibitor: X-ray structure and molecular modeling of enzyme-inhibitor complexes. The Journal of Biological Chemistry 279 (44), pp. 45990-45997.

Dove, Stefan and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2004) Structure-Activity Relationships of Histamine H_2 Receptor Ligands,. Mini-Rev. Med. Chem. 4 (9), pp. 941-954.

Parker, Steven L. and Parker, Michael S. and Buschauer, Armin and Balasubramaniam, Ambikaipakan (2003) Ligand internalization by cloned neuropeptide Y Y5 receptors excludes Y2 and Y4 receptor-selective peptides. European Journal of Pharmacology 474 (1), pp. 31-42.

Li, Liantao and Mayer, Matthias and Schneider, Erich and Schreiber, Elvira and Bernhardt, Günther and Peng, Shiqi and Buschauer, Armin (2003) Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A. Arch Pharm (Weinheim) 336 (12), pp. 585-590.

Li, Liantao and Kracht, Julia and Peng, Shiqi and Bernhardt, Günther and Elz, Sigurd and Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H2 receptor antagonists related to potentidine,. Bioorganic & Medicinal Chemistry Letters 13 (10), 0960-894.

Oettl, Martin and Hoechstetter, Julia and Asen, Iris and Bernhardt, Günther and Buschauer, Armin (2003) Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations. European Journal of Pharmaceutical Sciences 18 (3-4), pp. 267-277.

Seifert, Roland and Wenzel-Seifert, Katharina and Bürckstümmer, Tilmann and Pertz, Heinz H. and Schunack, Walter and Dove, Stefan and Buschauer, Armin and Elz, Sigurd (2003) Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor,. Journal of Pharmacology and Experimental Therapeutics 305, pp. 1104-1115.

Li, Liantao and Kracht, Julia and Peng, Shiqi and Bernhardt, Günther and Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine,. Bioorganic & Medicinal Chemistry Letters 13 (7), pp. 1245-1248.

Parker, S.L. and Parker, M. S. and Lundell, I. and Balasubramaniam, A. and Buschauer, Armin and Kane, J. K. and Yalcin, A. and Berglund, M. M. (2002) Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling. Regulatory Peptides 107 (1-3), pp. 49-62.

Vogelhuber, Werner and Spruß, Thilo and Bernhardt, Günther and Buschauer, Armin and Göpferich, Achim (2002) Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts,. International Journal of Pharmaceutics 238 (1-2), pp. 111-121.

Weiss, Thomas S. and Bernhardt, Günther and Buschauer, Armin and Thasler, Wolfgang E. and Dolgner, Doris and Zirngibl, Hubert and Jauch, Karl-Walter (2002) Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,. International Journal of Colorectal Disease 17 (6), pp. 381-387.

Fellner, Stephan and Bauer, Björn and Miller, David S. and Schaffrick, Martina and Fankhänel, Martina and Spruß, Thilo and Bernhardt, Günther and Graeff, Claudia and Färber, Lothar and Gschaidmeier, Harald and Buschauer, Armin and Fricker, Gert (2002) Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. The Journal of Clinical Investigation 110 (9), pp. 1309-1318.

Schuster, Andreas and Götte, Carsten and Bernhardt, Günther and Buschauer, Armin (2001) Chiral separation of pheniramine-like 3-phenyl-3-heteroarylpropylamines by CE and HPLC methods,. Chirality 13 (6), pp. 285-293.

Kelley, Melissa T. and Bürckstümmer, Tilmann and Wenzel-Seifert, Katharina and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2001) Distinct interaction of human and guinea pig histamine H_2-Receptor with guanidine-type agonists,. Molecular Pharmacology 60 (6), pp. 1210-1225.

Bischoff, Andrea and Püttmann, Kristina and Kötting, Annette and Moser, Christiane and Buschauer, Armin and Michel, Martin C. (2001) Limited signal transduction repertoire of human Y_5 neuropeptide Y receptors expressed in HEC-B cells. Peptides 22 (3), pp. 387-394.

Vogelhuber, W. and Rutunno, P. and Magni, E. and Gazzaniga, A. and Spruss, Thilo and Bernhardt, Günther and Buschauer, Armin and Goepferich, Achim (2001) Programmable biodegradable implants. Journal of Controlled Release 73 (1), pp. 75-88.

Wenzel-Seifert, Katharina and Kelley, Melissa T. and Buschauer, Armin and Seifert, Roland (2001) Similar apparent constitutive activity of human histamine H_2-receptor fused to long and short splice variants of Gsa,. Journal of Pharmacology and Experimental Therapeutics 299 (3), pp. 1013-1020.

Zabel, Manfred and Breu, Josef and Rau, Franz and Range, Klaus-Jürgen and Krey, Volker and Uffrecht, Anka and Buschauer, Armin (2000) Absolute configuration of (-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid: essential information to determine crucial steric feature of arpromidine-type histamine H_2 receptor agonists. Acta Crystallographica Section C 56, pp. 250-251.

Moser, Christiane and Bernhardt, Günther and Michel, J. and Schwarz, H. and Buschauer, Armin (2000) Cloning and functional expression of the hNPY Y_5 receptor in human endometrial cancer (HEC-1B) cells. Can J. Physiol. Pharmacol 78, pp. 134-142.

Buschauer, Armin and Bernhardt, Günther and Dove, Stefan (2000) NPY-Rezeptoren als Zielstrukturen für neue Arzneistoffe. Pharmazeutische Zeitung 24, pp. 11-18.

Dove, Stefan and Michel, Martin C. and Knieps, Sebastian and Buschauer, Armin (2000) Pharmacology and quantitative structure-activity relationships of imidazolylpropylguanidines with mepyramine-like substructures as non-peptide neuropeptide Y Y_1 receptor antagonists,. Can. J. Physiol. Pharmacol 78, pp. 108-115.

Aiglstorfer, Iris and Hendrich, Ingo and Moser, Christiane and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (2000) Structure-Activity Relationships of Neuropeptide Y Y_1 Receptor Antagonists Related to BIBP 3226,. Bioorganic & Medicinal Chemistry Letters 10 (14), pp. 1597-1600.

Meister, A. and Bernhardt, Günther and Christoffel, V. and Buschauer, Armin (1999) Antispasmodic Activity of Thymus vulgaris, Extract on the Isolated Guinea-Pig Trachea: Discrimination Between Drug and Ethanol Effects. Planta Med 1999, pp. 512-516.

Moser, Christiane and Bernhardt, Günther and Buschauer, Armin (1999) Efficient Transfection of Human Endometrial Cancer (HEC-1B) Cells with FuGENE^TM 6 Transfection Reagent. biochemica 1/1999, pp. 26-27.

Dove, Stefan and Buschauer, Armin (1999) Improved Alignment by Weighted Field Fit in CoMFA of Histamine H_2 Receptor Agonistic Imidazolylpropylguanidines. Quant. Struct.-Act. Relat. 18 (4), pp. 329-341.

Schuster, Andreas and Bernhardt, Günther and Eibler, Ernst and Buschauer, Armin and Hesselink, Willy (1998) Chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, and analogous guanidines and guanidine-N-carboxylic acid esters with HPLC and CZE. Journal of Chromatography A 793 (1), pp. 77-90.

Schulze, Frank R. and Buschauer, Armin and Schunack, Walter (1998) Combined histamine H_1/H_2 receptor antagonists: Part I. Pharmacological hybrids with pheniramine- and roxatidine-like substructures ,. European Journal of Pharmaceutical Sciences 6, pp. 177-186.

Wolf, Cornelia and Schulze, Frank R. and Buschauer, Armin and Schunack, Walter (1998) Combined histamine H_1/H_2 receptor antagonists: Part II. Pharmacological hybrids with pheniramine- and tiotidine-like substructures,. European Journal of Pharmaceutical Sciences 6 (3), pp. 187-196.

Dove, Stefan and Buschauer, Armin (1998) Imidazolylpropylguanidines as histamine H_2 receptor agonists: 3D-QSAR of a large series. Pharm. Acta Helv. 73 (3), pp. 145-155.

Aiglstorfer, Iris and Uffrecht, Anka and Geßele, K. and Moser, Christiane and Schuster, Andreas and Merz, S. and Malawska, B. and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (1998) NPY Y_1 antagonists: structure-activity relationships of arginine derivatives and hybrid compounds with arpromidine-like partial structures. Regul. Pept. 75, pp. 75-76.

Muckenschnabel, I. and Bernhardt, Günther and Spruß, Thilo and Buschauer, Armin (1998) Pharmacokinetics and tissue distribution of bovine testicular hyaluronidase and vinblastine in mice: an attempt to optimize the mode of adjuvant hyaluronidase administration in cancer chemotherapy. Cancer Letters 131 (1), pp. 71-84.

Muckenschnabel, Ingo and Bernhardt, Günther and Spruß, Thilo and Dietl, Barbara and Buschauer, Armin (1998) Quantitation of hyaluronidases by the Morgan-Elson reaction: comparison of the enzyme activities in the plasma of tumor patients and healthy volunteers. Cancer Letters 131, pp. 13-20.

Schuster, Andreas and Bollwein, Susanne and Uffrecht, Anka and Krey, Volker and Götte, Carsten and Bernhardt, Günther and Buschauer, Armin (1998) Stereochemical Investigations on Intermediates for the Synthesis of Histamine H_2 Receptor Agonists and Neuropeptide Y Y_1 Antagonists: Chiral Separation of Phenyl(pyridyl)alkanoic Acids by HPLC and CE. Sci. Pharm 66, pp. 263-278.

Muckenschnabel, I. and Bernhardt, Günther and Spruß, Thilo and Buschauer, Armin (1997) A versatile HPLC method for the measurement of melphalan tailored to the optimization of hyperthermic isolated limb perfusion,. Eur. J. Pharm. Sci. 5, pp. 129-137.

Schuster, Andreas and Bernhardt, Günther and Buschauer, Armin (1997) Determination of the arpromidine-type histamine H2-receptor agonist N1-[3-(3,4-difluoro­phe­nyl)-3-(2-pyridyl)propyl]-N2-[3-(1H-imidazol-4-yl)propyl]guanidine and corresponding N3-alkoxycarbonylguanidines by HPLC and CE. Eur. J. Pharm. Sci. 5, pp. 79-88.

Weiss, Thomas and Bernhardt, Günther and Buschauer, Armin and Jauch, Karl-Walter and Zirngibl, Hubert (1997) High-resolution RP HPLC analysis of polyamines and their monoacetyl conjugates by fluorescence detection after derivatization with N-hydroxy-succinimidyl 6-quinolinyl carbamate. Anal. Biochem 247, pp. 294-304.

Buschauer, Armin (1997) Pharmakotherapie der Tuberkulose: Wirkmechanismen und Resistenzen,. Pharm. Ztg. 142, pp. 209-223.

Dove, Stefan and Buschauer, Armin (1997) Stepwise leave-one-isomer-out Free-Wilson approaches as preprocessing tools in QSAR analysis of racemates. Quant. Struct.-Act. Relat. 16, pp. 11-19.

Müller, Manfred and Knieps, Sebastian and Geßele, Karin and Dove, Stefan and Bernhardt, Günther and Buschauer, Armin (1997) Synthesis and neuropeptide Y Y1 receptor antagonistic activity of N,N-disubstituted w -guanidino- and w -aminoalkanoic acid amides. Arch. Pharm. - Pharm. Med. Chem. (Weinheim) 330, pp. 333-342.

Muckenschnabel, Ingo and Bernhardt, Günther and Spruß, Thilo and Buschauer, Armin (1996) Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice. Cancer Chemother. Pharmacol 38, pp. 88-94.

Knieps, Sebastian and Dove, Stefan and Michel, Martin C. and Rottmeier, Karin and Wernet, W. and Bernhardt, Günther and Buschauer, Armin (1996) w -Phenyl-w -(2-pyridyl)alkyl-substituted bisguanidines are moderate neuropeptide Y antagonists. Pharm. Pharmacol. Lett. 6, pp. 27-30.

Glaß, D. and Buschauer, Armin and Tenor, H. and Bartel, S. and Will-Shahab, L. and Krause, E.-G. (1995) 4-(4-Guanidinobenzoyl)-2-imidazolones and related compounds: Phosphodiesterase inhibitors and novel cardiotonics with combined histamine H2 receptor agonist and PDE III inhibitor activity. Arch. Pharm. (Weinheim) 328, pp. 709-719.

Hagelüken, Astrid and Burde, Rahel and Nürnberg, Bern and Harhammer, R. and Buschauer, Armin and Seifert, Roland (1995) Cationic-amphiphilic arpromidine-derived guanidines and a histamine trifluoromethyl-toluidide derivative may activate pertussis toxin-sensitive G-proteins by a receptor-independent mechanism. Naunyn Schmiedeberg's Arch. Pharmacol. 351, pp. 305-308.

Coruzzi, Gabriela and Adami, Maristella and Pozzoli, Cristina and Buschauer, Armin and Bertaccini, Giulio (1995) Different activities of impromidine and related phenyl-(pyridylalkyl)guanidines at cardiac and gastric H_2 receptors. Inflamm. Res. 44 (Supl. 1), pp. 108-109.

Felix, Stefan B. and Buschauer, Armin and Baumann, Gert (1995) Haemodynamic profile of new H_2-receptor agonists in congestive heart failure. European Journal Of Clinical Investigation 25 (Suppl. 1), pp. 42-46.

Knieps, Sebastian and Michel, Martin C. and Dove, Stefan and Buschauer, Armin (1995) Non-peptide neuropeptide Y antagonists derived from the histamine H_2 agonist arpromidine: Role of the guanidine group. Bioorg. Med. Chem. Lett. 5, pp. 2065-2070.

Buschauer, Armin and Mohr, Rainer and Schunack, Walter (1995) Synthesis and histamine H_2-receptor antagonist activity of 4-(1-pyrazolyl)butanamides, guanidinopyrazoles, and related compounds. Arch. Pharm. (Weinheim) 328, pp. 349-358.

Rixen, D. and Neugebauer, E. and Lechleuthner, A. and Buschauer, Armin and Nagelschmidt, M. and Thoma, S. and Rink, A. (1994) Beneficial effect of H_2-agonism and H_1-antagonism in rat endotoxic shock ? Shock 2, pp. 47-52.

Kleine-Tebbe, Jörg and Josties, C. and Frank, G. and Stalleicken, D. and Buschauer, Armin and Schunack, Walter (1994) Inhibition of IgE- and non-IgE-mediated histamine release from human basophil leukocytes in vitro by a histamine H_1-antagonist, desethoxycarbonyl-loratadine. J. Allergy Clin. Immunol. 93, pp. 494-500.

Schulze, Frank R. and Alisch, Rudi A. and Buschauer, Armin and Schunack, Walter (1994) Synthese und kombinierte H_1-/H_2-antagonistische Aktivität von Mepyramin- Pheniramin- und Cyclizin-Derivaten mit Cyanoguanidin-, Harnstoff- und Nitroethendiamin-Partialstrukturen. Arch. Pharm. (Weinheim) 327, pp. 455-462.

Buschauer, Armin (1993) Diuretika - eine chemisch-pharmakologische Betrachtung. Pharm. Ztg. 138, pp. 177-188.

Stinner, B. and Hasse, C. and Lorenz, Wilfried and Alisch, Rudi and Schulze, Frank and Sitter, H. and Lüdke, U. and Buschauer, Armin and Schunack, Walter (1993) Effects of drugs combining H_1 and H_2 receptor antagonist activity on histamine release and life threatening anaphylactoid reactions in pigs. Agents Actions 38, Special Conference Issue, C286-C288.

Baumann, Gert and Buschauer, Armin and Felix, Stefan B. (1992) Hemodynamic profile of arpromidine and its F_2-substituted derivatives in comparison to impromidine in congestive heart failure. Agents Actions Special Conference Issue,, C329-C332.

Bungardt, Edwin and Buschauer, Armin and Moser, Ulrich and Schunack, Walter and Lambrecht, Günter and Mutschler, Ernst (1992) Histamine H_1-receptors mediate vasodilation in guinea-pig ileum resistance vessels: Characterization by the use of computer-assisted videomicroscopy and new selective agonists. Eur. J. Pharmacol. 221, pp. 91-98.

Sellier, Christian and Elz, Sigurd and Buschauer, Armin and Schunack, Walter (1992) Histamine analogues: imidazolylalkylguanidines, synthesis and in vitro pharmacology. European Journal of Medicinal Chemistry 27, pp. 27-32.

Seifert, Roland and Höer, Ariane and Offermann, Stefan and Buschauer, Armin and Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, pp. 227-234.

Seifert, Roland and Höer, Ariane and Schwaner, Ingo and Buschauer, Armin (1992) Histamine increases cytosolic Ca^2+ in HL-60 promyelocytes predominantly via H_2-receptors with an unique agonist/antagonist profile and induces functional differentiation. Molecular Pharmacology 42, pp. 235-241.

Hirschfeld, Jürgen and Buschauer, Armin and Elz, Sigurd and Schunack, Walter and Ruat, Martial and Traiffort, Elisabeth and Schwartz, Jean-Charles (1992) Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H_2-receptor. Journal of Medicinal Chemistry 35, pp. 2231-2238.

Klein-Tebbe, Jörg and Buschauer, Armin and Friese, Andrea and Schunack, Walter and Kunkel, G. (1992) Modulation of IgE-mediated histamine release from human leukocytes by a new class of histamine H_2-agonists. Agents Actions 35, pp. 185-191.

Michel, Martin C. and Buschauer, Armin (1992) Neuropeptide Y and its antagonists. Drugs Fut. 17, pp. 39-45.

Franke, Rainer and Buschauer, Armin (1992) Quantitative structure-activity relationships in histamine H_2-agonists related to impromidine and arpromidine. European Journal of Medicinal Chemistry 27, pp. 443-448.

Buschauer, Armin and Friese-Kimmel, Andrea and Baumann, Gert and Schunack, Walter (1992) Synthesis and histamine H_2 agonistic activity of arpromidine analogues: replacement of the pheniramine-like moiety by non-heterocyclic groups. European Journal of Medicinal Chemistry 27, pp. 321-330.

Buschauer, Armin and Lachenmayr, Friedhelm and Schunack, Walter (1992) Synthesis and histamine H_2-receptor activity of heterocyclic impromidine analogues. Pharmazie 47, pp. 86-91.

Sellier, Christian and Elz, Sigurd and Buschauer, Armin and Schunack, Walter (1992) The effect of lipophilic substituents on the H_2-histaminergic activity of some close analogues of impromidine. Arch. Pharm. (Weinheim) 325, pp. 471-476.

Sellier, Christian and Elz, Sigurd and Buschauer, Armin and Schunack, Walter (1992) Zur Synthese von (Z)- und (E)-3-(1H-imidazol-4-yl)-2-propenamin und einigen 3-(1H-Imidazol-4-yl)propanaminen. Liebigs Ann. Chem. 1992, pp. 317-322.

Ruat, Martial and Traiffort, E. and Bouthenet, M. L. and Pollard, H. and Moreau, J. and Schwartz, Jean-Charles and Martinez-Mir, I. and Palacios, J. M. and Hirschfeld, Jürgen and Buschauer, Armin and Schunack, Walter and Tertiuk, W. and Ganellin, C. Robin (1991) Reversible and irreversible labelling of H_1- and H_2-receptors using novel [^125I]probes. Agents Actions Suppl. 33, pp. 123-144.

Buschauer, Armin and Baumann, Gert (1991) Structure-activity relationships of histamine H_2-agonists, a new class of positive inotropic drugs. Agents Actions Suppl. 33, pp. 231-256.

Büyüktimkin, Servet and Buschauer, Armin and Schunack, Walter (1991) Synthese und H_1/H_2-antihistaminische Wirkung w-[2-Aryl-2,3-dihydro-4(1H)-chinazolinon-1-yl]alkyl-substituierter Harnstoffe und Cyanoguanidine. Arch. Pharm. (Weinheim) 324, pp. 291-295.

Buschauer, Armin and Lachenmayr, Friedhelm and Schunack, Walter (1991) Synthesis and histamine H_2-agonistic activity of ring-substituted phenyl analogues of impromidine. Pharmazie 46, pp. 841-845.

Felix, Stefan B. and Buschauer, Armin and Baumann, Gert (1991) Therapeutic value of H_2-receptor stimulation in congestive heart failure. Hemodynamic effects of BU-E-76, BU-E-75 and arpromidine (BU-E-50) in comparison to impromidine. Agents Actions Suppl. 33, pp. 257-269.

Mörsdorf, Peter and Engler, Heidrun and Schickaneder, Helmut and Buschauer, Armin and Schunack, Walter and Baumann, Gert (1990) Cardiohistaminergics - new developments in histamine H_2-agonists. Drugs of the Future 15, pp. 919-933.

Burde, Rahel and Buschauer, Armin and Seifert, Roland (1990) Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? Naunyn-Schmiedeberg's Archives of Pharmacology 341, pp. 455-461.

Meindl, Wolfgang and Friese-Kimmel, Andrea and Lachenmayr, Friedhelm and Buschauer, Armin and Schunack, Walter (1990) Der Einfluß von Agonisten und Antagonisten des Histamin-H_1- und H_2-Rezeptors auf das Wachstum von Mycobacterium tuberculosis H 37 Ra. Arch. Pharm. (Weinheim) 323, pp. 267-272.

Ruat, Martial and Traiffort, Elisabeth and Bouthenet, M. L. and Schwartz, Jean-Charles and Hirschfeld, Jürgen and Buschauer, Armin and Schunack, Walter (1990) Reversible and irreversible labeling and autoradiographic localization of the cerebral histamine H_2-receptor. Proc. Natl. Acad. Sci. USA 87, pp. 1658-1662.

Buschauer, Armin (1989) Entwicklung neuer positiv inotroper Arzneistoffe: Suche nach einem Digitalisersatz. Pharm. Ztg. Wiss. 2/134, pp. 3-16.

Burde, Rahel and Seifert, Roland and Buschauer, Armin and Schultz, Günther (1989) Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors. Naunyn-Schmiedeberg's archives of pharmacology 340, pp. 671-678.

Büyüktimkin, Servet and Buschauer, Armin and Schunack, Walter (1989) Synthese und pharmakologische Aktivität von 2-Aryl-1-((3-(imidazol-4-yl)propyl)guanidinoalkyl)-2,3-dihydro-4(1H)-chinazolinonen. Arch. Pharm. 322, pp. 115-118.

Buschauer, Armin (1989) Synthesis and in vitro pharmacology of arpromidine and related Phenylpyridyl­alkyl­guanidines, a potential new class of positive inotropic drugs. J. Med. Chem. 32, pp. 1963-1970.

Pawlowski, Maciej and Buschauer, Armin and Schunack, Walter (1989) Synthesis of Some 9-(Aminoalkyl)-6,7-dihydropyrimido[2,1-f]purine-2,4,8-(1H,3H,9H)-triones. Arch. Pharm. (Weinheim) 322, pp. 447-449.

Buschauer, Armin (1989) Zur Synthese primärer w-Phenyl-w-pyridylalkylamine. Arch. Pharm. (Weinheim) 322, pp. 165-171.

Mohr, R. and Buschauer, Armin and Schunack, Walter (1988) Basisch substituierte Aryloxyalkylguanidine und Analoge mit H_2-antagonistischer Wirkung. Arch. Pharm. (Weinheim) 321, pp. 221-227.

Elz, Sigurd and Kimmel, Ursula and Buschauer, Armin and Schunack, Walter (1988) Halogenderivate von N-[3-(Imidazol-4-yl)propyl]-N'-(2-phenylthioalkyl)guanidinen. Sci. Pharm. 56, pp. 229-234.

Buschauer, Armin (1988) Imidazolylalkylguanidine mit Diaryl-Partialstrukturen. Sci. Pharm. 56, pp. 81-88.

Baumann, Gert and Buschauer, Armin and Permanetter, Bernhard and Schunack, Walter (1988) Neue Aspekte zur Therapie der Myokardinsuffizienz. Inn. Med. 15 (Sonderausg.), pp. 30-38.

Buschauer, Armin (1988) Phenoxy- and Phenylthioalkylguanidines - Synthesis and in vitro Pharmacology. Eur. J. Med. Chem. 23, pp. 1-6.

Büyüktimkim, Nadir and Buschauer, Armin (1988) Separation and Determination of some Amino Acid Ester Enantiomers on TLC after Derivatization with Activated (S)-(+)-Naproxen. J. Chromatogr. 450, pp. 281-283.

Buschauer, Armin (1988) Synthese positiv inotroper Substanzen: Aryloxyalkylguanidine. Arch. Pharm. (Weinheim) 321, pp. 281-285.

Buschauer, Armin (1988) Synthese positiv inotroper Substanzen: Imidazolylpropylguanidine mit Pyridin-Partialstruktur,. Arch. Pharm. (Weinheim) 321, pp. 415-418.

Büyüktimkin, Servet and Buschauer, Armin and Schunack, Walter (1988) Synthese von 1-(Aminoalkyl)-2-aryl-2,3-dihydro-4(1H)-chinazolinonen. Arch. Pharm. (Weinheim) 321, pp. 833-834.

Keller, Frank and Buschauer, Armin and Schunack, Walter (1988) Synthese, Racemattrennung und pharmakologische Wirkung chiraler H_2-Antagonisten vom Aminomethylphenoxypropylamin-Typ. Pharm. Ztg. Wiss. 1/113, pp. 48-55.

Buschauer, Armin (1987) Arylmethylthioalkylguanidin-Derivate, Synthese und pharmakologische Wirkung. Arzneim.-Forsch. 37, pp. 1008-1012.

Buschauer, Armin (1987) Synthese und pharmakologische Wirkung substituierter Imidazolylalkyl- und Thiazolylalkylguanidine. Arzneim.-Forsch. 37, pp. 1003-1007.

Buschauer, Armin (1987) Synthese von N-Benzoyl- und N-Methansulfonyl-diphenylimidocarbonat. Arch. Pharm. (Weinheim) 320, pp. 377-378.

Mohr, Rainer and Buschauer, Armin and Schunack, Walter (1986) 1,3,5-Triazin-2,4-diamine und -2,4,6-triamine mit H2-antagonistischer Wirkung. Arch. Pharm. (Weinheim) 319, pp. 878-885.

Buschauer, Armin and Krämer, Irene and Schunack, Walter (1986) Synthese und H_2-antagonistische Wirkung 3-(3-piperidinomethyl-phenoxy)propyl-substituierter Kohlensäurederivate und Analoge. Arch. Pharm. (Weinheim) 319, pp. 434-443.

Buschauer, Armin (1985) 4-Aminopyrimidine mit H2-antihistaminischer Aktivität. Pharm. Ztg. Sci. Ed. 130, pp. 2067-2070.

Buschauer, Armin and Schunack, Walter (1985) Isocimetidin und Analoge. Arzneim.-Forsch. 35, pp. 1223-1224.

Buschauer, Armin and Postius, S. and Szelenyi, Istvan and Schunack, Walter (1985) Isohistamine und Homologe als Bausteine von H_2-Antagonisten. Arzneim.-Forsch. 35, pp. 1025-1029.

Buschauer, Armin and Schunack, Walter (1984) (8,9-Dihydro-7H-imidazo[1,2-c][1,3]diazepin-H)-one, -5(6H)-thione und -5(6H)-yliden­cyanamide. J. Heterocycl. Chem. 21, pp. 753-757.

Buschauer, Armin and Sattler, Hans-Joachim and Schunack, Walter (1984) 7,8-Dihydroimidazo[1,2-c]pyrimidin-5(6H)-one, -5(6H)-thione und -5(6H)-yliden­cyanamide. Chem. Ber. 117, pp. 2597-2614.

Buschauer, Armin and Wegner, Kurt and Schunack, Walter (1984) Isohistamine. Arch. Pharm. (Weinheim) 317, pp. 9-14.

Buschauer, Armin and Wegner, Kurt and Schunack, Walter (1983) 1,n-Bis(2-imidazolyl)alkane. Arch. Pharm. (Weinheim) 316, pp. 515-520.

Elz, Sigurd and Buschauer, Armin and Dräger, M. and Schunack, Walter (1983) Darstellung, Eigenschaften und Kristallstruktur der N-[2-(4,5,6,7-Tetrahydro-2-benzimidazolyl)ethyl]phthalamidsäure. Z. Naturforsch. 38b, pp. 1203-1207.

Buschauer, Armin and Schunack, Walter (1983) Die Struktur des N(pi)-Methylisohistamins - Eine Richtigstellung. Arch. Pharm. (Weinheim) 316, pp. 891-894.

Buschauer, Armin and Wegner, Kurt and Schunack, Walter (1982) Basisch substituierte Cimetidin-Analoge. Eur. J. Med. Chem. - Chim. Ther. 17, pp. 505-508.

Buschauer, Armin and Sattler, Hans-Joachim and Schunack, Walter (1982) Synthese von 2-(2-Aminoethyl)-4-hydroxymethyl-imidazol. Arch. Pharm. (Weinheim) 315, pp. 563-566.

Book Section

Schreeb, Annemarie and Łażewska, Dorota and Dove, Stefan and Buschauer, Armin and Kieć-Kononiwcz, Katarzyna and Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, pp. 21-62. ISBN 9788376560564.

Brennauer, Albert and Dove, Stefan and Buschauer, Armin (2004) 18. Structure-Activity Relationships of Nonpeptide Neuropeptide Y Receptor Antagonists. In: Michel, M. C., (ed.) Neuropeptide Y and Related Peptides. Handbook of Experimental Pharmacology, 162 (18). Springer, Heidelberg, pp. 505-546. ISBN 978-3-540-40581-8.

Baumann, Gert and Buschauer, Armin and Felix, Stefan B. (1994) Mögliche therapeutische Bedeutung sarkolemmaler Histamin-H_2-Rezeptoren bei Herzinsuffizienz: Hämodynamische Effekte neuer H_2-Agonisten. In: Greiling, H., (ed.) Pathobiochemie, Molekularbiologie und moderne Diagnostik kardiovaskulärer Erkrankungen. Springer, Berlin Heidelberg, pp. 104-115.

Franke, Rainer and Buschauer, Armin (1993) Interaction terms in Free-Wilson analysis: A QSAR of histamine H_2-agonists. In: Wermuth, C. G., (ed.) Trends in QSAR and Molecular Modelling 92. Escom, Leiden, pp. 160-162.

Buschauer, Armin and Baumann, Gert (1992) H_2-Agonisten des Arpromidin-Typs: Neue potentielle Arzneistoffe zur Behandlung der Herzinsuffizienz. In: Hirschelmann, R., (ed.) Entzündung und verwandte Reaktionen - Neue Erkenntnisse, neue Wirkstoffe. Jenapharm, Jena, pp. 192-203.

Klein-Tebbe, Jörg and Schramm, J. and Bolz, M. and Gagné, H. and Josties, C. and Lipp, Ralph and Friese, Andrea and Stark, Holger and Zingel, Volkmar and Buschauer, Armin and Fricker, Gert (1991) Influence of histamine H_1, H_2, and H_3 agonists and antagonists on IgE mediated histamine release from human basophils. In: Ring, J. and Przbilla, B., (eds.) New Trends in Allergy III. Springer, Berlin Heidelberg, pp. 152-157.

Buschauer, Armin and Schunack, Walter and Arrang, Jean-Michel and Garbarg, Monique (1989) Histamine Receptors. In: Williams, M. and Glennon, R. A. and Timmermans, P. B. M. W. M., (eds.) Receptor Pharmacology and Function. Series Clinical Pharmacology (series Ed. M. Weiner), 13. Marcel Dekker Inc., New York, pp. 293-347.

Baumann, Gert and Buschauer, Armin and Permanetter, Bernhard and Schunack, Walter (1989) Wiederherstellung der b_1-adrenergen Ansprechbarkeit bei Patienten mit Myokardinsuffizienz. In: Löllgen, H. and Just, H. and Meinertz, T., (eds.) Katecholamine in der Notfall- und Intensivmedizin. Perimed Verlag, Erlangen, pp. 28-42.

Baumann, Gert and Permanetter, Bernhard and Buschauer, Armin and Wirtzfeld, Alexander and Schunack, Walter (1987) Mögliche Bedeutung einer kardialen H_2-Rezeptor Stimulation bei Katecholamin-refraktärem Myokardversagen unterschiedlicher Ätiologie. In: Brisse, B. and Bender, F., (eds.) Autonome Innervation des Herzens - Myokardiale Hypoxie. Steinkopff-Verlag, Darmstadt, pp. 183-194.

Schunack, Walter and Buschauer, Armin and Büyüktimkim, Servet and Dziuron, Peter and Elz, Sigurd and Gerhardt, Günter and Lebenstedt, Ernst and Lennartz, Hans-Gerd and Schwarz, Siegfried and Spitzhoff, Margrit and Steffens, Robert (1985) 2. Histamine agonists - chemistry and structure-activity relationships. In: Dahlbom, R. and Nilsson, J. L. G., (eds.) VIIIth International Symposium on Medicinal Chemistry. Swedish Pharmaceutical Press, Stockholm, pp. 169-182.

Patent

Schickaneder, Helmut and Buschauer, Armin and Bernhardt, Günther and Schickaneder, Christian and Limmert, Michael and Huber, Stefan and Lubbe, Mathias and Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof.

Ertel, Miriam and Bernhardt, Günther and Nink, Jörg and Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems.

Alisch, Rudi and Schulze, Frank and Buschauer, Armin and Schunack, Walter (1991) Arylalkylaminderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Schweizer Patentanmeldung 02193/91-6 (22.07.1991).

Neugebauer, Edmund and Buschauer, Armin (1991) Verwendung von Guanidinderivaten zur Herstellung eines Arzneimittels zur Behandlung des Sepsis-Syndroms, des Sepsis-like Syndroms und des septischen Schocks. Deutsche Patentanmeldung P 41 19 696.1 (14.6.1991); Offen­legungsschrift DE 41 19 696 A 1 (17.12.1992); PCT Internat. Veröffentlichung WO 92/22295 (23.12.1992).

Mörsdorf, Peter and Schickaneder, Helmut and Pfahlert, Volker and Engler, Heidrun and Buschauer, Armin and Schunack, Walter (1987) Guanidin-Carbonsäureester, Verfahren zu ihrer Herstellung und diese Verbin­dun­gen enthaltende Arzneimittel. Patentanmeldung 37 26 381.1 (7.8.1987). , Deutsche Offenlegungsschrift DE 37 26 381 (8.2.1989); EP 0 302 164 (8.2.1989).

Buschauer, Armin and Schickaneder, Helmut and Elz, Sigurd and Schunack, Walter and Szelenyi, Istvan and Baumann, Gert and Ahrens, K.-H. (1986) Guanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthal­tende Arzneimittel. Patentanmeldung P 35 12 084.3 (2.4.1985), Offenlegungsschrift DE 35 12 084 A.

Schickaneder, Helmut and Mörsdorf, Peter and Buschauer, Armin and Schunack, Walter and Engler, Heidrun and Vergin, Hartmut and Ahrens, K.-H. (1986) 1,4-Dihydropyridinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthal­tende Arzneimittel. Patentanmeldung P 36 21 104.4 (24.6.1986), Offenlegungsschrift DE 36 21 104 A 1 (7.1.1988)..

Buschauer, Armin and Schunack, Walter and Baumann, Gert and Ahrens, K.-H. (1986) Neue Imidazolylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbin­dungen enthaltende Arzneimittel. Patentanmeldung P 36 31 334.3 (15.9.1986), Offenlegungsschrift DE 36 31 334 A1 (17.3.1988)..

Buschauer, Armin and Schickaneder, Helmut and Schunack, Walter and Szelenyi, Istvan and Ahrens, K.-H. (1985) Arylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung P 35 28 214.2 (6.8.1985), Offenlegungsschrift DE 35 28 214 (12.2.1987).

Buschauer, Armin and Schickaneder, Helmut and Schunack, Walter and Szelenyi, Istvan and Ahrens, Kurt-Henning (1985) Heteroarylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbin­dungen enthaltende Arzneimittel. Patentanmeldung P 35 28 215.0 (6.8.1985), Offenlegungsschrift DE 35 28 215 (12.2.1987).

Buschauer, Armin and Schickaneder, Helmut and Schunack, Walter and Elz, Sigurd and Szelenyi, Istvan and Baumann, Gert and Ahrens, K.-H. (1985) Imidazolylalkylguanidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung 85 114 205.9 (12.11.1985), Eur. Pat. Appl. EP 0 199 845 (5.11.1986).

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