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Anzahl der Einträge: 50.

2010

Ott, I., Kowalski, K., Gust, Ronald, Maurer, Jörg, Mücke, P. und Winter, Rainer F. (2010) Comparative biological evaluation of two ethylene linked mixed binuclear ferrocene/ruthenium organometallic species. Bioorg. Chem. Med. Lett 20, S. 866-869. Volltext nicht vorhanden.

2009

Gust, Ronald, Beck, Wolfgang, Jaouen, Gerard und Schönenberger, Helmut (2009) Optimization of cisplatin for the treatment of hormone dependent tumoral diseases Part.1. Use of steroidal ligands. Coordination Chemistry Reviews 253 (21-22), S. 2742-2759. Volltext nicht vorhanden.

Gust, Ronald, Beck, Wolfgang, Jaouen, Gerard und Schönenberger, Helmut (2009) Optimization of cisplatin for the treatment of hormone-dependent tumoral diseases Part.2 Use of non-steroidal ligands. Coordination chemistry reviews 253 (21-22), S. 2760-2779. Volltext nicht vorhanden.

2007

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Spruss, Thilo, Maucher, Anton, Angerer, Erwin von, Schiller, Claus D., Schneider, Martin R., Gust, Ronald und Schönenberger, Helmut (2007) Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies. Journal of Cancer Research and Clinical Oncology 133 (3), S. 153-167. Volltext nicht vorhanden.

2005

Gust, Ronald, Niebler, Karlheinz und Schönenberger, Helmut (2005) [N-Ethyl- and [N,N'-Diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II): Structure and Cytotoxic/Estrogenic Activity in Breast Cancer Cells. Journal of Medicinal Chemistry 48 (23), S. 7132-7144. Volltext nicht vorhanden.

2004

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruß, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald und Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level. Archiv der Pharmazie 337 (6), S. 335-348. Volltext nicht vorhanden.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruss, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald und Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity. Archiv der Pharmazie 337 (6), S. 349-359. Volltext nicht vorhanden.

2001

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther, Gust, Ronald und Schönenberger, Helmut (2001) 1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes--new biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties. Archiv der Pharmazie 334 (4), S. 125-137. Volltext nicht vorhanden.

2000

Gust, Ronald, Faderl, Michael und Schönenberger, Helmut (2000) [Aqua-1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine] sulfatoplatinum(II) complexes with variable substituents in the 2-phenyl ring 3. Investigation of breast cancer inhibiting properties. Journal of cancer research and clinical oncology 126 (11), S. 647-654. Volltext nicht vorhanden.

1999

Gust, Ronald, Heinrich, Heike, Krauser, Rudolf und Schönenberger, Helmut (1999) [Meso- and rac-1,2-bis(4-fluorophenyl)ethylenediamine]chloro[sulfinylbis(methane)-S]platinum(II) chloride new water soluble platinum complexes with high anti-breast cancer activities. Inorganica chimica acta 285 (2), S. 184-189. Volltext nicht vorhanden.

Bernhardt, Günther, Koch, Marion, Spruss, Thilo, Gust, Ronald, Krauser, Rudolf, Schlemmer, Richard, Hollstein, Michael, Lux, Franz und Schönenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] sulfatoplatinum(II)--pharmacokinetic studies. Archiv der Pharmazie 332 (6), S. 195-200. Volltext nicht vorhanden.

1998

Gust, Ronald, Schnurr, Beate, Krauser, Rudolf, Bernhardt, Günther, Koch, Marion, Schmid, Beate, Hummel, Evelyn und Schönenberger, Helmut (1998) Stability and cellular studies of [rac-1,2-bis(4-fluorophenyl)ethylenediamine][cyclobutane-1,1-dicarboxylato]platinum(II), a novel, highly active carboplatin derivative. Journal of Cancer Research and Clinical Oncology 124 (11), S. 585-597. Volltext nicht vorhanden.

Gust, Ronald, Krauser, Rudolf, Schmid, Beate und Schönenberger, Helmut (1998) Synthesis and antitumor activity of [1,2-bis(4-fluorophenyl)ethylenediamine][dicarboxylato]platinum(II) complexes. Archiv der Pharmazie 331 (1), S. 27-35. Volltext nicht vorhanden.

1997

Gust, Ronald, Gelbcke, Michael, Angermaier, Bernhard, Bachmann, Helmut, Krauser, Rudolf und Schönenberger, Helmut (1997) The stereoselectivity of antitumor active [1,2-diamino-1-phenylpropane]dichloroplatinum(II) complexes. Inorganica chimica acta 264 (1-2), S. 145-160. Volltext nicht vorhanden.

1996

Gust, Ronald, Krauser, Rudolf, Schmid, Beate und Schönenberger, Helmut (1996) Breast cancer inhibiting diastereomeric diacetato[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) derivatives: synthesis and studies on the relationship between reactivity and antitumor activity. Inorganica chimica acta 250 (1-2), S. 203-218. Volltext nicht vorhanden.

Klement, Ulrich, Range, K. J., Gust, Ronald und Schönenberger, Helmut (1996) Crystal structure of (Z)-[1-(2-chloro-5-methoxyphenyl)-2-(2,6-dichloro-4-methoxyphenyl)ethene], (CH3O)(C6H2Cl2)(CH)2(C6H3Cl)(OCH3). Zeitschrift für Kristallographie 211 (11), S. 850. Volltext nicht vorhanden.

1995

Gust, Ronald, Bernhardt, Günther, Spruss, Thilo, Krauser, Rudolf, Koch, Marion, Schönenberger, Helmut, Bauer, Kurt H., Schertl, Sabine und Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the "third generation platinum complex" [(+/-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie 328 (9), S. 645-653. Volltext nicht vorhanden.

Gust, Ronald, Bernhardt, Günther, Spruss, Thilo, Krauser, Rudolf, Koch, Marion, Schönenberger, Helmut, Bauer, Kurt-Heinz, Schertl, Sabine und Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the \"third generation platinum complex\" [(+-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie (Weinheim, Germany) 328 (9), S. 645-653. Volltext nicht vorhanden.

Gust, Ronald, Niebler, Karlheinz und Schönenberger, Helmut (1995) Investigation of the Configurational and Conformational Influences on the Hormonal Activity of 1,2-Bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines and of their Platinum(II) Complexes. 1. Synthesis, Estradiol Receptor Affinity, and Estrogenic Activity of Diastereomeric [N-Alkyl- and N,N'-Dialkyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) Complexes. Journal of Medicinal Chemistry 38 (12), S. 2070-2079. Volltext nicht vorhanden.

Gust, Ronald, Karl, Johann, Faderl, Michael und Schönenberger, Helmut (1995) Reduction of the estrogenic side effects of the mammary tumor-inhibiting drug [1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) by variation of ring substituents. Archiv der Pharmazie 328 (5), S. 457-463. Volltext nicht vorhanden.

Gust, Ronald und Schönenberger, Helmut (1995) Third generation antitumor platinum(II) complexes of the [1-(fluoro/difluorophenyl)-2-phenylethylenediamine]platinum(II) type. Archiv der Pharmazie 328 (7-8), S. 595-603. Volltext nicht vorhanden.

1994

Nikolov, G. S., Trendavilova, N., Schönenberger, Helmut, Gust, Ronald, Kritzenberger, J. und Yersin, Hartmut (1994) Molecular mechanical and quantum chemical study on the species involved in the hydrolysis of cis-diaminedichloro-platinum(II) and substituted bis(ethylenediamine)dichloro-platinum(II) complexes. Part I. Reactans and products. Inorganica Chimica Acta 217 (1-2), S. 159-170. Volltext nicht vorhanden.

Gust, Ronald und Schönenberger, Helmut (1994) Investigation of the Conformational influences on the estrogenic activity of 1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines and of their platinum(II) complexes, II. Synthesis and studies on the estrogenic activity of cis- and trans[bis(2,6-dichloro-4-hydroxybenzylamine)]dihaloplatinum(II) complexes. Archiv der Pharmazie 327 (12), S. 763-769. Volltext nicht vorhanden.

Nikolov, G. St, Trendafilova, N., Schönenberger, Helmut, Gust, Ronald, Kritzenberger, J. und Yersin, Hartmut (1994) Molecular mechanical and quantum chemical study on the species involved in the hydrolysis of cis-diamminedichloroplatinum(II) and substituted bis(ethylenediamine)dichloroplatinum(II) complexes. Part I. Reactants and products. Inorganica chimica acta 217 (1-2), S. 159-170. Volltext nicht vorhanden.

1993

Gust, Ronald, Schönenberger, Helmut, Klement, Ulrich und Range, Klaus Juergen (1993) Aqua[1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine]sulfatoplatinum(II) complexes with variable substituents in the 2-phenyl ring. II. Correlation of molecular structure and estrogenic activity of breast and prostate cancer inhibiting [erythro-1-(2,6-dichloro-4-hydroxyphenyl)-2-(2-halo-4-hydroxyphenyl)ethylenediamine]platinum(II) complexes. Archiv der Pharmazie 326 (12), S. 967-976. Volltext nicht vorhanden.

Gust, Ronald und Schönenberger, Helmut (1993) Breast cancer-inhibiting properties of leaving group derivatives of [1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]platinum(II). European Journal of Medicinal Chemistry 28 (2), S. 117-127. Volltext nicht vorhanden.

Gust, Ronald, Schönenberger, Helmut, Range, Klaus Juergen, Klement, Ulrich und Schneider, Martin (1993) Crystal structure and hormonal activity of 1,1-bis(4-hydroxyphenyl)-2-phenylethene. Monatshefte für Chemie 124 (11-12), S. 1181-1193. Volltext nicht vorhanden.

Gust, Ronald, Schönenberger, Helmut, Kritzenberger, Juergen, Range, Klaus Juergen, Klement, Ulrich und Burgemeister, Thomas (1993) Crystal structure, solution chemistry, and antitumor activity of diastereomeric [1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes. Inorganic chemistry 32 (26), S. 5939-5950. Volltext nicht vorhanden.

Kritzenberger, J, Bernhardt, Günther, Gust, Ronald, Pistor, Petra, Schönenberger, Helmut und Yersin, Hartmut. (1993) Dichlorobis(cycloalkylamine)platinum(II) complexes. Structure activity relationship on the human MDA-MB-231 breast cancer cell line. Monatshefte fuer Chemie 124 (5), S. 587-604.

Gust, Ronald und Schönenberger, Helmut (1993) Mammary tumor inhibiting [1,2-bis(2,6-dihalo-3-hydroxyphenyl)ethylenediamine]platinum(II) complexes. III. Relationship between structure and estrogenic activity of the diamine ligands, their sulfatoplatinum(II) and diiodoplatinum(II) complexes. Archiv der Pharmazie 326 (7), S. 405-413. Volltext nicht vorhanden.

Gust, Ronald und Schönenberger, Helmut (1993) Synthesis and evaluation of the anti-mammary tumor activity and of the estrogenic side effects of [1,2-bis(2,6-dihalo-3-hydroxyphenyl)ethylenediamine]platinum(II) complexes. European journal of medicinal chemistry 28 (2), S. 103-115. Volltext nicht vorhanden.

Spruss, Thilo, Schertl, Sabine, Schneider, Martin R., Gust, Ronald, Bauer, Kurt und Schönenberger, Helmut (1993) [Meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] -dichloroplatinum(II), a new drug not only parenterally but also orally active in the therapy of breast and prostate cancer. Journal of cancer research and clinical oncology 119 (12), S. 707-716. Volltext nicht vorhanden.

1992

Bernhardt, Günther, Müller, Richard, Gust, Ronald, Reile, Herta, Keller, Christoph, Spruss, Thilo und Schönenberger, Helmut (1992) Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3. Archiv der Pharmazie 325 (2), S. 93-99.

Schertl, Sabine, Gust, Ronald, Müller, Richard, Spruss, Thilo und Schönenberger, Helmut (1992) Stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]platinum(II) complexes. Part III. Evaluation of the mammary tumor inhibiting properties. Archiv der Pharmazie 325 (2), S. 113-118. Volltext nicht vorhanden.

Bernhardt, Günther, Gust, Ronald, Reile, Herta, vom Orde, Hans Dieter, Müller, Richard, Keller, Christoph, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas, Mannschreck, Albrecht, Range, Klaus-Jürgen und Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. II. Synthesis and preliminary testing of the enantiomeric complexes. Journal of cancer research and clinical oncology 118 (3), S. 201-208.

Bernhardt, Günther, Gust, Ronald, Reile, Herta, vom Orde, Hans Dieter, Müller, Richard, Keller, Christoph, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas, Mannschreck, Albrecht, Range, Klaus Jürgen und Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. III. Detailed evaluation of the antitumor activity of the enantiomeric complexes on the human NIH:OVCAR-3 ovarian cancer cell line. Journal of cancer research and clinical oncology 118 (3), S. 209-215.

1991

Bernhardt, Günther, Reile, Herta, Spruss, Thilo, Koch, Marion, Gust, Ronald, Schönenberger, Helmut, Hollstein, Michael, Lux, Franz und Engel, Jürgen (1991) D-17446. Drugs of the Future 16 (10), S. 899-903.

Müller, Richard, Gust, Ronald, Klement, Ulrich und Schönenberger, Helmut (1991) Stereoisomeric dichloro[1-(hydroxyphenyl)-2-phenyl-1,2-ethanediamine]platinum(II) complexes. I. Synthesis. Chemische Berichte 124 (11), S. 2381-2389. Volltext nicht vorhanden.

Reile, Herta, Spruß, Thilo, Bernhardt, Günther, Müller, Richard, Gust, Ronald und Schönenberger, Helmut (1991) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part IV: Biological evaluation--in vivo studies on the P 388 leukemia. Archiv der Pharmazie 324 (7), S. 405-409.

1990

Gust, Ronald, Burgemeister, Thomas, Mannschreck, Albrecht und Schönenberger, Helmut (1990) Aqua[1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine](sulfato)platinum(II) complexes with variable substituents in the 2-phenyl ring. 1. Synthesis and antitumor and estrogenic properties. Journal of medicinal chemistry 33 (9), S. 2535-2544. Volltext nicht vorhanden.

Spruss, Thilo, Gust, Ronald, Müller, Richard, Engel, Juergen und Schönenberger, Helmut (1990) Mammary-tumor-inhibiting properties of (S,S)-[1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II). Archiv der Pharmazie 323 (2), S. 99-102. Volltext nicht vorhanden.

Reile, Herta, Spruß, Thilo, Müller, Richard, Gust, Ronald, Bernhardt, Günther, Schönenberger, Helmut und Engel, Jürgen (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes, III: Evaluation of the mammary tumor inhibiting properties. Archiv der Pharmazie 323 (5), S. 301-306.

Reile, Herta, Müller, Richard, Gust, Ronald, Laske, Reiner, Krischke, Walter, Bernhardt, Günther, Spruss, Thilo, Jennerwein, Margaretha, Engel, Jürgen und Seeber, Siegfried (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part II: Biological evaluation-in vitro studies on the P 388 D1 leukemia cell line. Archiv der Pharmazie 323 (3), S. 133-140.

vom Orde, Hans Dieter, Reile, Herta, Müller, Richard, Gust, Ronald, Bernhardt, Günther, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas und Mannschreck, Albrecht (1990) Tumor-inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. V. Synthesis and evaluation of enantiomeric [1,2-bis-(4-fluorophenyl)ethylenediamine]dichloroplatinum(II) complexes. Journal of cancer research and clinical oncology 116 (5), S. 434-438.

Müller, Richard, Gust, Ronald, Bernhardt, Günther, Keller, Christoph, Schönenberger, Helmut, Seeber, Siegfried, Osieka, Reinhardt, Eastman, Alan und Jennerwein, Margaretha (1990) [DL-1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. Journal of cancer research and clinical oncology 116 (3), S. 237-244.

1989

Mueller, Richard, Gust, Ronald, Jennerwein, Margaretha, Reile, Herta, Laske, Reiner, Krischke, Walter, Bernhardt, Günther, Spruss, Thilo, Engel, Juergen und Schönenberger, Helmut (1989) Tumor inhibiting [1,2-bis(fluorophenylethylenediamine]platinum(II) complexes. Part I. Synthesis. European Journal of Medicinal Chemistry 24 (4), S. 341-348.

Jennerwein, Margaretha, Gust, Ronald, Müller, Richard, Schönenberger, Helmut, Engel, Juergen, Berger, Martin R., Schmaehl, Dietrich, Seeber, Siegfried und Osieka, Reinhardt (1989) Tumor inhibiting properties of stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes. Part I. Synthesis. Archiv der Pharmazie 322 (1), S. 25-29. Volltext nicht vorhanden.

Jennerwein, Margaretha, Gust, Ronald, Müller, Richard, Schönenberger, Helmut, Engel, Juergen, Berger, Martin R., Schmaehl, Dietrich, Seeber, Siegfried und Osieka, Reinhardt (1989) Tumor inhibiting properties of stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II)-complexes. Part II. Biological properties. Archiv der Pharmazie 322 (2), S. 67-73. Volltext nicht vorhanden.

1988

Jennerwein, M., Wappes, B., Gust, Ronald, Schönenberger, Helmut, Engel, J., Seeber, S. und Osieka, R. (1988) Influence of ring substituents on the antitumor effect of dichloro(1,2-diphenylethylenediamine)platinum(II) complexes. Journal of cancer research and clinical oncology 114 (4), S. 347-358. Volltext nicht vorhanden.

Karl, Johann, Gust, Ronald, Spruss, Thilo, Schneider, Martin R., Schönenberger, Helmut, Engel, Juergen, Wrobel, Karl Heinz, Lux, Franz und Trebert-Haeberlin, Susanne (1988) Ring-substituted [1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes: compounds with a selective effect on the hormone-dependent mammary carcinoma. Journal of medicinal chemistry 31 (1), S. 72-83. Volltext nicht vorhanden.

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