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Article

Ott, I. and Kowalski, K. and Gust, Ronald and Maurer, Jörg and Mücke, P. and Winter, Rainer F. (2010) Comparative biological evaluation of two ethylene linked mixed binuclear ferrocene/ruthenium organometallic species. Bioorg. Chem. Med. Lett 20, pp. 866-869.

Gust, Ronald and Beck, Wolfgang and Jaouen, Gerard and Schönenberger, Helmut (2009) Optimization of cisplatin for the treatment of hormone dependent tumoral diseases Part.1. Use of steroidal ligands. Coordination Chemistry Reviews 253 (21-22), pp. 2742-2759.

Gust, Ronald and Beck, Wolfgang and Jaouen, Gerard and Schönenberger, Helmut (2009) Optimization of cisplatin for the treatment of hormone-dependent tumoral diseases Part.2 Use of non-steroidal ligands. Coordination chemistry reviews 253 (21-22), pp. 2760-2779.

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Spruss, Thilo and Maucher, Anton and Angerer, Erwin von and Schiller, Claus D. and Schneider, Martin R. and Gust, Ronald and Schönenberger, Helmut (2007) Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies. Journal of Cancer Research and Clinical Oncology 133 (3), pp. 153-167.

Gust, Ronald and Niebler, Karlheinz and Schönenberger, Helmut (2005) [N-Ethyl- and [N,N'-Diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II): Structure and Cytotoxic/Estrogenic Activity in Breast Cancer Cells. Journal of Medicinal Chemistry 48 (23), pp. 7132-7144.

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Bernhardt, Günther and Spruß, Thilo and Beckenlehner, Karin and Koch, Marion and Krauser, Rudolf and Schlemmer, Richard and Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level. Archiv der Pharmazie 337 (6), pp. 335-348.

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Bernhardt, Günther and Spruss, Thilo and Beckenlehner, Karin and Koch, Marion and Krauser, Rudolf and Schlemmer, Richard and Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity. Archiv der Pharmazie 337 (6), pp. 349-359.

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Schlemmer, Richard and Spruß, Thilo and Bernhardt, Günther and Gust, Ronald and Schönenberger, Helmut (2001) 1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes--new biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties. Archiv der Pharmazie 334 (4), pp. 125-137.

Gust, Ronald and Faderl, Michael and Schönenberger, Helmut (2000) [Aqua-1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine] sulfatoplatinum(II) complexes with variable substituents in the 2-phenyl ring 3. Investigation of breast cancer inhibiting properties. Journal of cancer research and clinical oncology 126 (11), pp. 647-654.

Gust, Ronald and Heinrich, Heike and Krauser, Rudolf and Schönenberger, Helmut (1999) [Meso- and rac-1,2-bis(4-fluorophenyl)ethylenediamine]chloro[sulfinylbis(methane)-S]platinum(II) chloride new water soluble platinum complexes with high anti-breast cancer activities. Inorganica chimica acta 285 (2), pp. 184-189.

Bernhardt, Günther and Koch, Marion and Spruss, Thilo and Gust, Ronald and Krauser, Rudolf and Schlemmer, Richard and Hollstein, Michael and Lux, Franz and Schönenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] sulfatoplatinum(II)--pharmacokinetic studies. Archiv der Pharmazie 332 (6), pp. 195-200.

Gust, Ronald and Schnurr, Beate and Krauser, Rudolf and Bernhardt, Günther and Koch, Marion and Schmid, Beate and Hummel, Evelyn and Schönenberger, Helmut (1998) Stability and cellular studies of [rac-1,2-bis(4-fluorophenyl)ethylenediamine][cyclobutane-1,1-dicarboxylato]platinum(II), a novel, highly active carboplatin derivative. Journal of Cancer Research and Clinical Oncology 124 (11), pp. 585-597.

Gust, Ronald and Krauser, Rudolf and Schmid, Beate and Schönenberger, Helmut (1998) Synthesis and antitumor activity of [1,2-bis(4-fluorophenyl)ethylenediamine][dicarboxylato]platinum(II) complexes. Archiv der Pharmazie 331 (1), pp. 27-35.

Gust, Ronald and Gelbcke, Michael and Angermaier, Bernhard and Bachmann, Helmut and Krauser, Rudolf and Schönenberger, Helmut (1997) The stereoselectivity of antitumor active [1,2-diamino-1-phenylpropane]dichloroplatinum(II) complexes. Inorganica chimica acta 264 (1-2), pp. 145-160.

Gust, Ronald and Krauser, Rudolf and Schmid, Beate and Schönenberger, Helmut (1996) Breast cancer inhibiting diastereomeric diacetato[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) derivatives: synthesis and studies on the relationship between reactivity and antitumor activity. Inorganica chimica acta 250 (1-2), pp. 203-218.

Klement, Ulrich and Range, K. J. and Gust, Ronald and Schönenberger, Helmut (1996) Crystal structure of (Z)-[1-(2-chloro-5-methoxyphenyl)-2-(2,6-dichloro-4-methoxyphenyl)ethene], (CH3O)(C6H2Cl2)(CH)2(C6H3Cl)(OCH3). Zeitschrift für Kristallographie 211 (11), p. 850.

Gust, Ronald and Bernhardt, Günther and Spruss, Thilo and Krauser, Rudolf and Koch, Marion and Schönenberger, Helmut and Bauer, Kurt H. and Schertl, Sabine and Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the "third generation platinum complex" [(+/-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie 328 (9), pp. 645-653.

Gust, Ronald and Bernhardt, Günther and Spruss, Thilo and Krauser, Rudolf and Koch, Marion and Schönenberger, Helmut and Bauer, Kurt-Heinz and Schertl, Sabine and Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the \"third generation platinum complex\" [(+-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie (Weinheim, Germany) 328 (9), pp. 645-653.

Gust, Ronald and Niebler, Karlheinz and Schönenberger, Helmut (1995) Investigation of the Configurational and Conformational Influences on the Hormonal Activity of 1,2-Bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines and of their Platinum(II) Complexes. 1. Synthesis, Estradiol Receptor Affinity, and Estrogenic Activity of Diastereomeric [N-Alkyl- and N,N'-Dialkyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) Complexes. Journal of Medicinal Chemistry 38 (12), pp. 2070-2079.

Gust, Ronald and Karl, Johann and Faderl, Michael and Schönenberger, Helmut (1995) Reduction of the estrogenic side effects of the mammary tumor-inhibiting drug [1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) by variation of ring substituents. Archiv der Pharmazie 328 (5), pp. 457-463.

Gust, Ronald and Schönenberger, Helmut (1995) Third generation antitumor platinum(II) complexes of the [1-(fluoro/difluorophenyl)-2-phenylethylenediamine]platinum(II) type. Archiv der Pharmazie 328 (7-8), pp. 595-603.

Nikolov, G. S. and Trendavilova, N. and Schönenberger, Helmut and Gust, Ronald and Kritzenberger, J. and Yersin, Hartmut (1994) Molecular mechanical and quantum chemical study on the species involved in the hydrolysis of cis-diaminedichloro-platinum(II) and substituted bis(ethylenediamine)dichloro-platinum(II) complexes. Part I. Reactans and products. Inorganica Chimica Acta 217 (1-2), pp. 159-170.

Gust, Ronald and Schönenberger, Helmut (1994) Investigation of the Conformational influences on the estrogenic activity of 1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines and of their platinum(II) complexes, II. Synthesis and studies on the estrogenic activity of cis- and trans[bis(2,6-dichloro-4-hydroxybenzylamine)]dihaloplatinum(II) complexes. Archiv der Pharmazie 327 (12), pp. 763-769.

Nikolov, G. St and Trendafilova, N. and Schönenberger, Helmut and Gust, Ronald and Kritzenberger, J. and Yersin, Hartmut (1994) Molecular mechanical and quantum chemical study on the species involved in the hydrolysis of cis-diamminedichloroplatinum(II) and substituted bis(ethylenediamine)dichloroplatinum(II) complexes. Part I. Reactants and products. Inorganica chimica acta 217 (1-2), pp. 159-170.

Gust, Ronald and Schönenberger, Helmut and Klement, Ulrich and Range, Klaus Juergen (1993) Aqua[1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine]sulfatoplatinum(II) complexes with variable substituents in the 2-phenyl ring. II. Correlation of molecular structure and estrogenic activity of breast and prostate cancer inhibiting [erythro-1-(2,6-dichloro-4-hydroxyphenyl)-2-(2-halo-4-hydroxyphenyl)ethylenediamine]platinum(II) complexes. Archiv der Pharmazie 326 (12), pp. 967-976.

Gust, Ronald and Schönenberger, Helmut (1993) Breast cancer-inhibiting properties of leaving group derivatives of [1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]platinum(II). European Journal of Medicinal Chemistry 28 (2), pp. 117-127.

Gust, Ronald and Schönenberger, Helmut and Range, Klaus Juergen and Klement, Ulrich and Schneider, Martin (1993) Crystal structure and hormonal activity of 1,1-bis(4-hydroxyphenyl)-2-phenylethene. Monatshefte für Chemie 124 (11-12), pp. 1181-1193.

Gust, Ronald and Schönenberger, Helmut and Kritzenberger, Juergen and Range, Klaus Juergen and Klement, Ulrich and Burgemeister, Thomas (1993) Crystal structure, solution chemistry, and antitumor activity of diastereomeric [1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes. Inorganic chemistry 32 (26), pp. 5939-5950.

Kritzenberger, J and Bernhardt, Günther and Gust, Ronald and Pistor, Petra and Schönenberger, Helmut and Yersin, Hartmut. (1993) Dichlorobis(cycloalkylamine)platinum(II) complexes. Structure activity relationship on the human MDA-MB-231 breast cancer cell line. Monatshefte fuer Chemie 124 (5), pp. 587-604.

Gust, Ronald and Schönenberger, Helmut (1993) Mammary tumor inhibiting [1,2-bis(2,6-dihalo-3-hydroxyphenyl)ethylenediamine]platinum(II) complexes. III. Relationship between structure and estrogenic activity of the diamine ligands, their sulfatoplatinum(II) and diiodoplatinum(II) complexes. Archiv der Pharmazie 326 (7), pp. 405-413.

Gust, Ronald and Schönenberger, Helmut (1993) Synthesis and evaluation of the anti-mammary tumor activity and of the estrogenic side effects of [1,2-bis(2,6-dihalo-3-hydroxyphenyl)ethylenediamine]platinum(II) complexes. European journal of medicinal chemistry 28 (2), pp. 103-115.

Spruss, Thilo and Schertl, Sabine and Schneider, Martin R. and Gust, Ronald and Bauer, Kurt and Schönenberger, Helmut (1993) [Meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] -dichloroplatinum(II), a new drug not only parenterally but also orally active in the therapy of breast and prostate cancer. Journal of cancer research and clinical oncology 119 (12), pp. 707-716.

Bernhardt, Günther and Müller, Richard and Gust, Ronald and Reile, Herta and Keller, Christoph and Spruss, Thilo and Schönenberger, Helmut (1992) Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3. Archiv der Pharmazie 325 (2), pp. 93-99.

Schertl, Sabine and Gust, Ronald and Müller, Richard and Spruss, Thilo and Schönenberger, Helmut (1992) Stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]platinum(II) complexes. Part III. Evaluation of the mammary tumor inhibiting properties. Archiv der Pharmazie 325 (2), pp. 113-118.

Bernhardt, Günther and Gust, Ronald and Reile, Herta and vom Orde, Hans Dieter and Müller, Richard and Keller, Christoph and Spruß, Thilo and Schönenberger, Helmut and Burgemeister, Thomas and Mannschreck, Albrecht and Range, Klaus-Jürgen and Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. II. Synthesis and preliminary testing of the enantiomeric complexes. Journal of cancer research and clinical oncology 118 (3), pp. 201-208.

Bernhardt, Günther and Gust, Ronald and Reile, Herta and vom Orde, Hans Dieter and Müller, Richard and Keller, Christoph and Spruß, Thilo and Schönenberger, Helmut and Burgemeister, Thomas and Mannschreck, Albrecht and Range, Klaus Jürgen and Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. III. Detailed evaluation of the antitumor activity of the enantiomeric complexes on the human NIH:OVCAR-3 ovarian cancer cell line. Journal of cancer research and clinical oncology 118 (3), pp. 209-215.

Bernhardt, Günther and Reile, Herta and Spruss, Thilo and Koch, Marion and Gust, Ronald and Schönenberger, Helmut and Hollstein, Michael and Lux, Franz and Engel, Jürgen (1991) D-17446. Drugs of the Future 16 (10), pp. 899-903.

Müller, Richard and Gust, Ronald and Klement, Ulrich and Schönenberger, Helmut (1991) Stereoisomeric dichloro[1-(hydroxyphenyl)-2-phenyl-1,2-ethanediamine]platinum(II) complexes. I. Synthesis. Chemische Berichte 124 (11), pp. 2381-2389.

Reile, Herta and Spruß, Thilo and Bernhardt, Günther and Müller, Richard and Gust, Ronald and Schönenberger, Helmut (1991) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part IV: Biological evaluation--in vivo studies on the P 388 leukemia. Archiv der Pharmazie 324 (7), pp. 405-409.

Gust, Ronald and Burgemeister, Thomas and Mannschreck, Albrecht and Schönenberger, Helmut (1990) Aqua[1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine](sulfato)platinum(II) complexes with variable substituents in the 2-phenyl ring. 1. Synthesis and antitumor and estrogenic properties. Journal of medicinal chemistry 33 (9), pp. 2535-2544.

Spruss, Thilo and Gust, Ronald and Müller, Richard and Engel, Juergen and Schönenberger, Helmut (1990) Mammary-tumor-inhibiting properties of (S,S)-[1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II). Archiv der Pharmazie 323 (2), pp. 99-102.

Reile, Herta and Spruß, Thilo and Müller, Richard and Gust, Ronald and Bernhardt, Günther and Schönenberger, Helmut and Engel, Jürgen (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes, III: Evaluation of the mammary tumor inhibiting properties. Archiv der Pharmazie 323 (5), pp. 301-306.

Reile, Herta and Müller, Richard and Gust, Ronald and Laske, Reiner and Krischke, Walter and Bernhardt, Günther and Spruss, Thilo and Jennerwein, Margaretha and Engel, Jürgen and Seeber, Siegfried (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part II: Biological evaluation-in vitro studies on the P 388 D1 leukemia cell line. Archiv der Pharmazie 323 (3), pp. 133-140.

vom Orde, Hans Dieter and Reile, Herta and Müller, Richard and Gust, Ronald and Bernhardt, Günther and Spruß, Thilo and Schönenberger, Helmut and Burgemeister, Thomas and Mannschreck, Albrecht (1990) Tumor-inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. V. Synthesis and evaluation of enantiomeric [1,2-bis-(4-fluorophenyl)ethylenediamine]dichloroplatinum(II) complexes. Journal of cancer research and clinical oncology 116 (5), pp. 434-438.

Müller, Richard and Gust, Ronald and Bernhardt, Günther and Keller, Christoph and Schönenberger, Helmut and Seeber, Siegfried and Osieka, Reinhardt and Eastman, Alan and Jennerwein, Margaretha (1990) [DL-1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. Journal of cancer research and clinical oncology 116 (3), pp. 237-244.

Mueller, Richard and Gust, Ronald and Jennerwein, Margaretha and Reile, Herta and Laske, Reiner and Krischke, Walter and Bernhardt, Günther and Spruss, Thilo and Engel, Juergen and Schönenberger, Helmut (1989) Tumor inhibiting [1,2-bis(fluorophenylethylenediamine]platinum(II) complexes. Part I. Synthesis. European Journal of Medicinal Chemistry 24 (4), pp. 341-348.

Jennerwein, Margaretha and Gust, Ronald and Müller, Richard and Schönenberger, Helmut and Engel, Juergen and Berger, Martin R. and Schmaehl, Dietrich and Seeber, Siegfried and Osieka, Reinhardt (1989) Tumor inhibiting properties of stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes. Part I. Synthesis. Archiv der Pharmazie 322 (1), pp. 25-29.

Jennerwein, Margaretha and Gust, Ronald and Müller, Richard and Schönenberger, Helmut and Engel, Juergen and Berger, Martin R. and Schmaehl, Dietrich and Seeber, Siegfried and Osieka, Reinhardt (1989) Tumor inhibiting properties of stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II)-complexes. Part II. Biological properties. Archiv der Pharmazie 322 (2), pp. 67-73.

Jennerwein, M. and Wappes, B. and Gust, Ronald and Schönenberger, Helmut and Engel, J. and Seeber, S. and Osieka, R. (1988) Influence of ring substituents on the antitumor effect of dichloro(1,2-diphenylethylenediamine)platinum(II) complexes. Journal of cancer research and clinical oncology 114 (4), pp. 347-358.

Karl, Johann and Gust, Ronald and Spruss, Thilo and Schneider, Martin R. and Schönenberger, Helmut and Engel, Juergen and Wrobel, Karl Heinz and Lux, Franz and Trebert-Haeberlin, Susanne (1988) Ring-substituted [1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes: compounds with a selective effect on the hormone-dependent mammary carcinoma. Journal of medicinal chemistry 31 (1), pp. 72-83.

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