|Up a level|
Chen, W. and Oberwinkler, H. and Werner, F. and Gaßner, B. and Nakagawa, H, and Feil, R. and Hofmann, F. and Schlossmann, Jens and Dietrich, A. and Gudermann, T. and Nishida, M. and Del Galdo, S. and Wieland, T. and Kuhn, M. (2013) ANP-mediated inhibition of microcirculatory endothelial Ca 2+ and permeability response to histamine involves cGMP-dependent protein kinase I and TRPC6 channels. Arteriosclerosis, Thrombosis, and Vascular Biology 33 (9), pp. 2121-2129. (In Press)
Schinner, E. and Schramm, A. and Kees, F. and Hofmann, F. and Schlossmann, Jens (2013) Suppression of kidney fibrosis by cGMP-dependent protein Kinase Ia. Kidney International. (In Press)
Luo, C. and Gangadharan, V. and Bali, K.K. and Xie, R.G. and Agarwal, N. and Kurejova, M. and Tappe-Theodor, A. and Tegeder, I. and Feil, S. and Lewin, G. and Polgar, E. and Todd, A.J. and Schlossmann, Jens and Hofmann, F. and Liu, D.L. and Hu, S.J. and Feil, R. and Kuner, T. and Kuner, R. (2012) Presynaptically localized cyclic GMP-dependent Protein Kinase I is a key determinant of spinal potentiation and pain hypersensitivity. PLoS Biology 10 (3), 1e1001283.
Ertl, C. and Lukowski, R. and Sigl, K and Schlossmann, Jens and Hofmann, F. and Wegener, Jörg W. (2011) Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle. Eur J Pharmacol 670 (1), pp. 266-271.
Werder, A. and Mayr, M. and Schneider, G. and Oesterle, D. and Fritsch, R. M. and Seidler, B. and Schlossmann, Jens and Hofmann, F. and Schemann, M. and Allescher, H. D. and Schmid, R.M. and Saur, D. (2011) Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction. American Journal of Physiology - Cell Physiology : Am J Physiol Cell Physiol 301 (6), C1445-1457.
Desch, Matthias and Schinner, Elisabeth and Kees, Frieder K. and Hofmann, F. and Seifert, Roland and Schlossmann, Jens (2010) Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I. FEBS Letters 584 (18), pp. 3979-3984.
Desch, M. and Sigl, K. and Hieke, B. and Salb, Katharina and Kees, Frieder and Bernhard, D. and Jochim , A. and Spiessberger, B. and Höcherl, K. and Feil, R. and Lukowski, R. and Wegener, Jörg W. and Hofmann, F. and Schlossmann, Jens (2010) IRAG determines NO- and ANP-mediated smooth muscle relaxation. Cardiovascular Research 86 (3), pp. 496-505.
Frei, E. and Huster, M. and Smital, P. and Schlossmann, Jens and Hofmann, F. and Wegener, Jörg W. (2009) Calcium-dependent and Calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle. American Journal of Physiology 297, G834-839.
Schlossmann, Jens and Hofmann, F. (2008) Receptor mediated mechanisms. In: Greim, H. and Snyder, R., (eds.) Toxicology and risk assessment : a comprehensive introduction. Wiley, Chicester. ISBN 978-0-470-86893-5.
Antl, M. and von Brühl, M. L. and Eigslperger, C. and Werner, M. and Konrad, I. and Köcher, T. and Wilm, M. and Hofmann, F. and Massberg, S. and Schlossmann, Jens (2007) IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation. Blood 109, pp. 552-559.
Sausbier, M. and Zhou, X.B. and Beier, C. and Sausbier, U. and Wolpers , D. and Maget, S. and Martin, C. and Dietrich, A. and Ressmeyer, A.R. and Schlossmann, Jens and Hofmann, F. and Neuhuber, W. and Gudermann, T. and Uhlig, S. and Korth, M. and Ruth, P. (2007) Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+channel. FASEB Journal 21, pp. 812-822.
Weber, S. and Bernhard, D. and Lukowski, R. and Weinmeister, P. and Wörner, R. and Wegener, J. W. and Valtcheva, N. and Feils, S. and Schlossmann, Jens and Hofmann, F. and Feil, R. (2007) Rescue of cGMP Kinase I knockout mice by smooth muscle specific expression of either isozyme. Circulation Research 101, pp. 1096-1103.
Hofmann, F. and Feil, R. and Kleppisch, T. and Schlossmann, Jens (2006) Function of cGMP-dependent Protein Kinase as revealed by gene deletion. Physiological Reviews 86, pp. 1-23.
Feil, S. and Zimmermann, P. and Knorn, A. and Brummer, S. and Schlossmann, Jens and Hofmann, F. and Feil, R. (2005) Distribution of cGMP-dependent protein kinase type 1 and its isoforms in the mouse brain and retina. Neuroscience 135, pp. 863-868.
Schlossmann, Jens and Feil, R. and Hofmann, F. (2005) Insights into cGMP signaling derived from cGMP Kinase knockout mice. Frontiers in Bioscience 10, pp. 1279-1289.
Werner, C.G. and Godrey, V. and Arnold, R.R. and Featherstone, G.L. and Bender, D. and Schlossmann, Jens and Schiemann, M. and Hofmann, F. and Pryzwansky, K.B. (2005) Neutrophil dysfunction in guanosine 3',5'-cyclic monophosphate-dependent protein kinase I-deficient mice. Journal of Immunology 175, pp. 1919-1929.
Schlossmann, Jens and Hofmann, F. (2005) cGMP-dependent protein kinases in drug discovery. Drug Discovery Today 10, pp. 627-634.
Geiselhöringer, A. and Gaisa, M. and Hofmann, F. and Schlossmann, Jens (2004) Distribution of IRAG and cGKI-isoforms in murine tissues. FEBS Letters 575, pp. 19-22.
Geiselhöringer, A. and Werner, M. and Sigl, K. and Smital, P. and Wörner, R. and Acheo, L. and Stieber, J. and Weinmeister, P. and Feil, R. and Feil, S. and Wegener, J. and Hofmann, F. and Schlossmann, Jens (2004) IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP Kinase. EMBO Journal 23, pp. 4222-4231.
Fritsch, R.M. and Saur, D. and Kurjak , M. and Oesterle, D. and Schlossmann, Jens and Geiselhöringer, A. and Hofmann, F. and Allescher, H.D. (2004) InsP3R-associated cGMP kinase substrate (IRAG) is essential for nitric oxide-induced inhibition of calcium signaling in human colonic smooth muscle. J. Biol. Chem. 279, pp. 12551-12559.
Koller, A. and Schlossmann, Jens and Ashman, K. and Uttenweiler-Joseph, S. and Ruth, P. l. and Hofmann, F. (2003) Association of phospholamban with a cGMP kinase signaling complex. Biochemical and Biophysical Research Communications : Biochem. Biophys. Res. Commun. 300, pp. 155-160.
Schlossmann, Jens and Feil, R. and Hofmann, F. (2003) Signaling through NO and cGMP-dependent protein kinases. Annals of Medicine 35, pp. 21-27.
Feil, R. and Gappa, N. and Rutz, M. and Schlossmann, Jens and Rose, C.R. and Konnerth, A. and Brummer, S. and Hofmann, F. (2002) Functional Reconstitution of vascular smooth muscle cells with cGMP-dependent protein kinase I isoforms. Circulation Research : Circ. Res. 90, pp. 1080-1086.
Ammendola, A. and Geiselhöringer, A. and Hofmann, F. and Schlossmann, Jens (2001) Molecular Determinants of the Interaction between the Inositol 1,4,5-Trisphosphate Receptor-associated cGMP Kinase Substrate (IRAG) and cGMP Kinase Iβ. J. Biol. Chem. 276, pp. 24153-24159.
Schlossmann, Jens and Ammendola, A. and Ashman, K. and Zong, X and Huber, A. and Neubauer, G. and Wang, G. X. and Allescher, H. D. and Korth, M. and Wilm, M. and Hofmann, F. and Ruth, P. (2000) Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta. Nature 404, pp. 197-201.
Hofmann, F. and Ammendola, A. and Schlossmann, Jens (2000) Rising behind NO: cGMP-dependent protein kinases. Journal of cell science : J. Cell Sci. 113, pp. 1671-1676.
Zhou, X.B. and Schlossmann, Jens and Hofmann, F. and Ruth, P. and Korth, M. (1998) Regulation of stably expressed and native BK channels from human myometrium by cGMP- and cAMP-dependent protein kinase. Pflügers Archiv : European journal of physiology 436, pp. 725-734.
Zhou , X. B. and Ruth, P. and Schlossmann, Jens and Hofmann, F. and Korth, M. (1996) Protein Phosphatase 2A Is Essential for the Activation of Ca2+-activated K+ Currents by cGMP-dependent Protein Kinase in Tracheal Smooth Muscle and Chinese Hamster Ovary Cells. Journal of Biological Chemistry : J. Biol Chem 271, pp. 19760-19767.
Hoffmann, H. and Hofmann, F. and Schoepe, Wilfried (1982) Magnetoresistance and non-Ohmic conductivity of thin platinum films at low temperatures. Physical Review B (PRB) 25 (8), pp. 5563-5565.