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Article

Holler, Ernst and Butzhammer, Peter and Schmid, Karin and Hundsrucker, Christian and Koestler, Josef and Peter, Katrin and Zhu, Wentao and Sporrer, Daniela and Hehlgans, Thomas and Kreutz, Marina and Holler, Barbara and Wolff, Daniel and Edinger, Matthias and Andreesen, Reinhard and Levine, John E. and Ferrara, James L and Gessner, Andre and Spang, Rainer and Oefner, Peter J. (2014) Metagenomic analysis of the stool microbiome in patients receiving allogeneic SCT: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal GvHD. Biology of Blood and Marrow Transplantation 20 (5), pp. 640-645.

Dettmer, Katja and Vogl, Franziska C. and Ritter, Axel P. and Zhu, Wentao and Nürnberger, Nadine and Kreutz, Marina and Oefner, Peter J. and Gronwald, Wolfram and Gottfried, Eva (2013) Distinct metabolic differences between various human cancer and primary cells. ELECTROPHORESIS 34 (19), pp. 2836-2847.

Kreutz, Marina and Gottfried, Eva and Lang, Sven A. and Renner, Kathrin and Bosserhoff, Anja-Katrin and Gronwald, Wolfram and Rehli, Michael and Einhell, Sabine and Gedig, Isabell and Singer, Katrin and Seilbeck, Anton and Mackensen, Andreas and Grauer, Oliver and Hau, Peter and Dettmer, Katja and Andreesen, Reinhard and Oefner, Peter (2013) New aspects of an old drug: Diclofenac targets MYC and glucose metabolism in tumor cells. PLoS ONE 8 (7), e66987.

Chirasani, Sridhar Reddy and Leukel, Petra and Gottfried, Eva and Hochrein, Jochen and Stadler, Katrin and Neumann, Bernhard and Oefner, Peter J. and Gronwald, Wolfram and Bogdahn, Ulrich and Hau, Peter and Kreutz, Marina and Grauer, Oliver M. (2013) Diclofenac inhibits lactate formation and efficiently counteracts local immune suppression in a murine glioma model. International journal of cancer. Journal international du cancer 132 (4), pp. 843-53.

Chirasani, Sridhar R. and Leukel, Petra and Gottfried, Eva and Hochrein, Jochen and Stadler, Katrin and Neumann, Bernhard and Oefner, Peter J. and Gronwald, Wolfram and Bogdahn, Ulrich and Hau, Peter and Kreutz, Marina and Grauer, Oliver M. (2013) Diclofenac inhibits lactate formation and efficiently counteracts local immune suppression in a murine glioma model. International journal of cancer 132 (4), pp. 843-853.

Seliger, Corinna and Leukel, Petra and Moeckel, Sylvia and Jachnik, Birgit and Lottaz, Claudio and Kreutz, Marina and Brawanski, Alexander and Proescholdt, Martin and Bogdahn, Ulrich and Bosserhoff, Anja-Katrin and Vollmann-Zwerenz, Arabel and Hau, Peter (2013) Lactate-Modulated Induction of THBS-1 Activates Transforming Growth Factor (TGF)-beta2 and Migration of Glioma Cells In Vitro. PloS one 8 (11), e78935.

Zhu, Wentao and Stevens, Axel Peter and Dettmer, Katja and Gottfried, Eva and Hoves, Sabine and Kreutz, Marina and Holler, Ernst and Canelas, André B. and Kema, Ido and Oefner, Peter J. (2011) Quantitative profiling of tryptophan metabolites in serum, urine, and cell culture supernatants by liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry 401 (10), pp. 3249-3261.

Landfried, Karin and Zhu, Wentao and Waldhier, Magdalena Ch. and Schulz, Ute and Ammer, Julia and Holler, Barbara and Wolff, Daniel and Edinger, Matthias and Peter, Katrin and Kreutz, Marina and Andreesen, Reinhard and Oefner, Peter J. and Holler, Ernst (2011) Tryptophan catabolism is associated with acute GVHD after human allogeneic stem cell transplantation and indicates activation of indoleamine 2,3-dioxygenase. Blood 118 (26), pp. 6971-6974.

Dietl, Katrin and Renner, Kathrin and Dettmer, Katja and Timischl, Birgit and Eberhart, Karin and Dorn, Christoph and Hellerbrand, Claus and Kastenberger, Michael and Kunz-Schughart, Leoni A. and Oefner, Peter J. and Andreesen, Reinhard and Gottfried, Eva and Kreutz, Marina (2010) Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes. Journal of immunology 184 (3), pp. 1200-1209.

Amann, Thomas and Maegdefrau, Ulrike and Hartmann, Arndt and Agaimy, Abbas and Marienhagen, Jörg and Weiss, Thomas S. and Stoeltzing, Oliver and Warnecke, Christina and Schölmerich, Jürgen and Oefner, Peter J. and Kreutz, Marina and Bosserhoff, Anja-Katrin and Hellerbrand, Claus (2009) GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis. The American journal of pathology 174 (4), pp. 1544-1552.

Stevens, Axel Peter and Spangler, Barbara and Wallner, Susanne and Kreutz, Marina and Dettmer, Katja and Oefner, Peter J. and Bosserhoff, Anja-Katrin (2009) Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma. Journal of cellular biochemistry 106 (2), pp. 210-219.

Baumann, Fusun and Leukel, Petra and Doerfelt, Anett and Beier, Christoph P. and Dettmer, Katja and Oefner, Peter J. and Kastenberger, Michael and Kreutz, Marina and Nickl-Jockschat, Thomas and Bogdahn, Ulrich and Bosserhoff, Anja-Katrin and Hau, Peter (2009) Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro-oncology 11 (4), pp. 368-380.

Fischer, Karin and Hoffmann, Petra and Voelkl, Simon and Meidenbauer, Norbert and Ammer, Julia and Edinger, Matthias and Gottfried, Eva and Schwarz, Sabine and Rothe, Gregor and Hoves, Sabine and Renner, Kathrin and Timischl, Birgit and Mackensen, Andreas and Kunz-Schughart, Leoni and Andreesen, Reinhard and Krause, Stefan W. and Kreutz, Marina (2007) Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood 109 (9), pp. 3812-9.

Gottfried, Eva and Kunz-Schughart, Leoni A. and Andreesen, Reinhard and Kreutz, Marina (2006) Brave little world: spheroids as an in vitro model to study tumor-immune-cell interactions. Cell cycle (Georgetown, Tex.) 5 (7), pp. 691-695.

Gottfried, Eva and Kunz-Schughart, Leoni A. and Ebner, Stephanie and Mueller-Klieser, Wolfgang and Hoves, Sabine and Andreesen, Reinhard and Mackensen, Andreas and Kreutz, Marina (2006) Tumor-derived lactic acid modulates dendritic cell activation and antigen expression. Blood 107 (5), pp. 2013-2021.

Gottfried, Eva and Rehli, Michael and Hahn, Joachim and Holler, Ernst and Andreesen, Reinhard and Kreutz, Marina (2006) Monocyte-derived cells express CYP27A1 and convert vitamin D3 into its active metabolite. Biochemical and biophysical research communications 349 (1), pp. 209-13.

Gottfried, Eva and Faust, Stefan and Fritsche, Jana and Kunz-Schughart, Leoni A. and Andreesen, Reinhard and Miyake, Kensuke and Kreutz, Marina (2003) Identification of genes expressed in tumor-associated macrophages. Immunobiology 207 (5), pp. 351-9.

Fritsche, Jana and Müller, Alexandra and Hausmann, Martin and Rogler, Gerhard and Andreesen, Reinhard and Kreutz, Marina (2003) Inverse regulation of the ADAM-family members, decysin and MADDAM/ADAM19 during monocyte differentiation. Immunology 110 (4), pp. 450-7.

Fritsche, Jana and Mondal, Krishna and Ehrnsperger, Achim and Andreesen, Reinhard and Kreutz, Marina (2003) Regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase and production of 1 alpha,25-dihydroxyvitamin D3 by human dendritic cells. Blood 102 (9), pp. 3314-6.

Uphoff, C. C. and Hu, Z. B. and Gignac, S. M. and Ma, W. and Rainey, F. A. and Kreutz, Marina and Ludwig, W. D. and Drexler, H. G. (1994) Characterization of the monocyte-specific esterase (MSE) gene. Leukemia 8 (9), pp. 1510-1526.

Schlesier, M. and Krause, S. and Dräger, R. and Wolff-Vorbeck, G. and Kreutz, Marina and Andreesen, Reinhard and Peter, H. H. (1994) Monocyte differentiation and accessory function: different effects on the proliferative responses of an autoreactive T cell clone as compared to alloreactive or antigen-specific T cell lines and primary mixed lymphocyte cultures. Immunobiology 190 (1-2), pp. 164-174.

Kreutz, Marina and Andreesen, Reinhard and Krause, S. W. and Szabo, A. and Ritz, E. and Reichel, H. (1993) 1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages. Blood 82 (4), pp. 1300-1307.

Krause, S. W. and Kreutz, Marina and Zenke, G. and Andreesen, Reinhard (1992) Developmental regulation of granulocyte-macrophage colony-stimulating factor production during human monocyte-to-macrophage maturation. Annals of hematology 64 (4), pp. 190-195.

Kreutz, Marina and Krause, S. W. and Hennemann, B. and Rehm, A. and Andreesen, Reinhard (1992) Macrophage heterogeneity and differentiation: defined serum-free culture conditions induce different types of macrophages in vitro. Research in immunology 143 (1), pp. 107-115.

Brugger, W. and Kreutz, Marina and Andreesen, Reinhard (1991) Macrophage colony-stimulating factor is required for human monocyte survival and acts as a cofactor for their terminal differentiation to macrophages in vitro. Journal of leukocyte biology 49 (5), pp. 483-488.

Kreutz, Marina and Andreesen, Reinhard (1990) Induction of human monocyte to macrophage maturation in vitro by 1,25-dihydroxyvitamin D3. Blood 76 (12), pp. 2457-2461.

Andreesen, Reinhard and Scheibenbogen, C. and Kreutz, Marina and Krause, S. and Rehm, A. (1990) Regulation of neopterin secretion during human monocyte to macrophage differentiation in vitro. Pteridines 2 (1), pp. 59-61.

Andreesen, Reinhard and Brugger, W. and Scheibenbogen, C. and Kreutz, Marina and Leser, H. G. and Rehm, A. and Löhr, G. W. (1990) Surface phenotype analysis of human monocyte to macrophage maturation. Journal of leukocyte biology 47 (6), pp. 490-497.

Book Section

Andreesen, Reinhard and Kreutz, Marina (1994) Differentiation of human monocytes in vitro. A model of macrophage ontogeny. In: Fusenig, N.E. and Graf, H., (eds.) Cell Culture in Pharmaceutical Research. Springer, Berlin, pp. 9-27. ISBN 3540581413; 978-3540581413.

Thesis

Kreutz, Marina (1992) Induktion der Differenzierung humaner Monozyten in vitro durch Vitamin D3-Metabolite und definierte Serumproteine. PhD, Univ. Freiburg.

Other

Kreutz, Marina and Andreesen, Reinhard and Briesen, H. v. and Rübsamen-Waigmann, H. and Ackermann, U. and Seack, K.H. and Sander, U. (1994) Makrophagen-Differenzierung humaner Monozyten zu Makrophagen in vitro. Institut für den wissenschaftlichen Film, Göttingen.

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