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Artikel

Lamontain, Vanessa, Schmid, Tobias, Weber-Steffens, Dorothea, Zeller, David, Jenei-Lanzl, Zsuzsa, Wajant, Harald, Straub, Rainer H. und Männel, Daniela N. (2019) Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice. Cellular & Molecular Immunology 16 (1), S. 65-74. Volltext nicht vorhanden.

Schmid, Tobias, Falter, Lena, Weber, Sabine, Müller, Nils, Molitor, Konstantin, Zeller, David, Weber-Steffens, Dorothea, Hehlgans, Thomas, Wajant, Harald, Mostböck, Sven und Männel, Daniela N. (2017) Chronic Inflammation Increases the Sensitivity of Mouse Treg for TNFR2 Costimulation. Frontiers in Immunology 8. Volltext nicht vorhanden.

Männel, Daniela N., Schmidt, Dominic, Peterlik, Daniel, Reber, Stefan Oskar und Lechner, Anja (2016) Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice. PLoS ONE 11 (7), e0159059.

Chopra, Martin, Biehl, Marlene, Steinfatt, Tim, Brandl, Andreas, Kums, Juliane, Amich, Jorge , Vaeth, Martin , Kuen, Janina, Holtappels, Rafaela, Podlech, Jürgen, Mottok, Anja, Kraus, Sabrina, Jordán-Garrote, Ana-Laura, Bäuerlein, Carina A., Brede, Christian, Ribechini, Eliana, Fick, Andrea, Seher, Axel, Polz, Johannes, Ottmüller, Katja J., Baker, Jeanette, Nishikii, Hidekazu, Ritz, Miriam, Mattenheimer, Katharina, Schwinn, Stefanie, Winter, Thorsten, Schäfer, Viktoria, Krappmann, Sven , Einsele, Hermann, Müller, Thomas D., Reddehase, Matthias J., Lutz, Manfred B., Männel, Daniela N., Berberich-Siebelt, Friederike, Wajant, Harald und Beilhack, Andreas (2016) Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion. The Journal of Experimental Medicine 213 (9), S. 1881-1900. Volltext nicht vorhanden.

Werner-Klein, Melanie, Proske, Judith, Werno, Christian, Schneider, Katharina, Hofmann, Hans-Stefan, Rack, Brigitte, Buchholz, Stefan, Ganzer, Roman, Blana, Andreas, Seelbach-Göbel, Birgit, Nitsche, Ulrich, Männel, Daniela N. und Klein, Christoph A. (2014) Immune Humanization of Immunodeficient Mice Using Diagnostic Bone Marrow Aspirates from Carcinoma Patients. PLoS ONE 9 (5), e97860.

Wege, Anja K., Huber, Barbara, Wimmer, Nadin, Männel, Daniela N. und Hehlgans, Thomas (2013) LTβR expression on hematopoietic cells regulates acute inflammation and influences maturation of myeloid subpopulations. Innate Immunity 20, S. 461-470.

Martin, E. M., Remke, A., Pfeifer, E., Polz, Johannes, Pietryga-Krieger, A., Steffens-Weber, D., Freudenberg, M., Mostböck, Sven und Männel, Daniela N. (2013) TNFR2 maintains adequate IL-12 production by dendritic cells in inflammatory responses by regulating endogenous TNF levels. Innate Immunity 20, S. 712-720.

Barth, Thomas, Schmidt, Dominic, Botteron, Catherine, Nguyen, Trang T. T., Ritter, Uwe, Männel, Daniela N. und Lechner, Anja (2012) An Early Reduction in Treg Cells Correlates with Enhanced Local Inflammation in Cutaneous Leishmaniasis in CCR6-Deficient Mice. Plos One 7, e44499.

Echtenacher, Bernd, Männel, Daniela N. und Hültner, L. (1994) REDUCED EARLY TNF CORRELATES WITH INCREASED MORTALITY OF MAST CELL-DEFICIENT MICE AFTER EXPERIMENTAL PERITONITIS. Journal Of Investigative Dermatology 103 (4), S. 621. Volltext nicht vorhanden.

Grau, G. E. und Männel, Daniela N. (1994) Strategies for inhibition of tumor necrosis factor in vivo. Trends in microbiology 2 (9), S. 303-305.

Piguet, P. F., Remick, D., Mueller, C., Ruddle, N. H. und Männel, Daniela N. (1993) TNF IN PATHOLOGY: OLD FACTS AND NEW QUESTIONS. DISCUSSION. Research in immunology 144 (5), S. 385-387. Volltext nicht vorhanden.

Westenfelder, U., Schraven, B. und Männel, Daniela N. (1993) Characterization of monocyte-activating tumour cell membrane structures. Scandinavian journal of immunology 38 (4), S. 388-394.

Orosz, P., Echtenacher, Bernd, Falk, Werner, Rüschoff, J., Weber, D. und Männel, Daniela N. (1993) Enhancement of experimental metastasis by tumor necrosis factor. The Journal of experimental medicine 177 (5), S. 1391-1398.

Männel, Daniela N., Rüschoff, J. und Orosz, P. (1993) The role of TNF in tumour growth and metastasis. Research in immunology 144 (5), S. 364-369.

Stiemer, R. H., Westenfelder, U., Gausepohl, H., Mirshahi, M., Gundt, A., Frank, R. W. und Männel, Daniela N. (1992) A common epitope on human tumor necrosis factor alpha and the autoantigen 'S-antigen/arrestin' induces TNF-alpha production. Journal of autoimmunity 5 (1), S. 15-26.

Stiemer, R. H., Westenfelder, U., de Kozak, Y., Gausepohl, H., Mirshahi, M., Frank, R. W., Faure, J. P. und Männel, Daniela N. (1992) Cytokine induction by immunomodulatory epitopes in S-antigen and tumor necrosis factor alpha. Current eye research 11 Sup, S. 197-202.

Ganter, S., Northoff, H., Männel, Daniela N. und Gebicke-Härter, P. J. (1992) Growth control of cultured microglia. Journal of neuroscience research 33 (2), S. 218-230.

Müller-Quernheim, J., Pfeifer, S., Männel, Daniela N., Strausz, J. und Ferlinz, R. (1992) Lung-restricted activation of the alveolar macrophage/monocyte system in pulmonary sarcoidosis. The American review of respiratory diseases 145 (1), S. 187-192.

Schlehofer, J. R., Rentrop, M. und Männel, Daniela N. (1992) Parvoviruses are inefficient in inducing interferon-beta, tumor necrosis factor-alpha, or interleukin-6 in mammalian cells. Medical microbiology and immunology 181 (3), S. 153-164.

Männel, Daniela N., Becker, H., Gundt, A., Kist, A. und Franz, H. (1991) Induction of tumor necrosis factor expression by a lectin from Viscum album. Cancer immunology, immunotherapy : CII 33 (3), S. 177-182.

Urbaschek, R., Männel, Daniela N. und Urbanczik, R. (1991) Isoniazid protects mice against endotoxin lethality without influencing tumor necrosis factor synthesis and release. Antimicrobial agents and chemotherapy 35 (8), S. 1666-1668.

Hass, R., Lonnemann, G., Männel, Daniela N., Topley, N., Hartmann, A., Köhler, L., Resch, K. und Goppelt-Strübe, M. (1991) Regulation of TNF-alpha, IL-1 and IL-6 synthesis in differentiating human monoblastoid leukemic U937 cells. Leukemia research 15 (5), S. 327-339.

Strausz, J., Männel, Daniela N., Pfeifer, S., Borkowski, A., Ferlinz, R. und Müller-Quernheim, J. (1991) Spontaneous monokine release by alveolar macrophages in chronic sarcoidosis. International archives of allergy and applied immunology 96 (1), S. 68-75.

Jänicke, R. und Männel, Daniela N. (1990) Distinct tumor cell membrane constituents activate human monocytes for tumor necrosis factor synthesis. The Journal of Immunology 144 (3), S. 1144-1150.

Ho, A. D., Männel, Daniela N., Wulf, G., Kirchner, H., Gundt, A., Trede, I., Rensch, K. und Hunstein, W. (1990) Long-term effects of 2'-deoxycoformycin treatment on cytokine production in patients with hairy cell leukemia. Leukemia 4 (8), S. 584-589. Volltext nicht vorhanden.

Männel, Daniela N., Jänicke, R., Westenfelder, U., Echtenacher, Bernd und Falk, W. (1990) TUMOR-INDUCED TUMOR-NECROSIS-FACTOR PRODUCTION IN MACROPHAGES. Lymphokine research 9 (4), S. 562. Volltext nicht vorhanden.

Männel, Daniela N. und Jänicke, R. (1989) Induction of monokine production by tumor cells. Lymphokine research 8 (3), S. 257-261.

Flegel, W. A., Wölpl, A., Männel, Daniela N. und Northoff, H. (1989) Inhibition of endotoxin-induced activation of human monocytes by human lipoproteins. Infection and immunity 57 (7), S. 2237-2245.

Männel, Daniela N., Kist, A., Ho, A. D., Räth, U., Reichardt, P., Wiedenmann, B., Schlick, E. und Kirchner, H. (1989) Tumour necrosis factor production and natural killer cell activity in peripheral blood during treatment with recombinant tumour necrosis factor. British journal of cancer 60 (4), S. 585-588.

Jänicke, R. und Männel, Daniela N. (1988) INDUCTION OF TNF-MRNA EXPRESSION AND TNF PRODUCTION IN HUMAN-MONOCYTES BY TUMOR-CELLS. Immunobiology 178 (1-2), S. 21. Volltext nicht vorhanden.

Kojouharoff, G., Männel, Daniela N., Krammer, P. H. und Falk, W. (1988) PURIFICATION OF T-CELL-CYTOTOXICITY-INDUCING-FACTOR-1 (TCF-1), A LYMPHOKINE INVOLVED IN THE DIFFERENTIATION OF CYTO-TOXIC T-CELLS. Immunobiology 178 (1-2), S. 82. Volltext nicht vorhanden.

Kist, A., Ho, A. D., Räth, U., Wiedenmann, B., Bauer, A., Schlick, E., Kirchner, H. und Männel, Daniela N. (1988) Decrease of natural killer cell activity and monokine production in peripheral blood of patients treated with recombinant tumor necrosis factor. Blood 72 (1), S. 344-348.

Andus, T., Northoff, H., Bauer, J., Ganter, U., Männel, Daniela N., Tran-Thi, T. A., Decker, K. und Heinrich, P. C. (1988) Induction of the proteinase inhibitor alpha 2-macroglobulin in rat hepatocytes by a monocyte-derived factor. Advances in experimental medicine and biology 240, S. 191-198. Volltext nicht vorhanden.

Northoff, H., Andus, T., Geiger, T., Bauer, J., Männel, Daniela N., Hirano, T., Kishimoto, T. und Heinrich, P. C. (1987) INDUCTION IN RAT HEPATOCYTES HEPATOMA-CELLS OF THE ACUTE PHASE RESPONSE - EFFECTS OF DIFFERENT MEDIATORS. Journal of leukocyte biology 42 (5), S. 566-567. Volltext nicht vorhanden.

Kojouharoff, G., von Hoegen, I., Männel, Daniela N., Krammer, P. H. und Falk, Werner (1987) CHARACTERIZATION OF T-CELL-CYTOTOXICITY-INDUCING-FACTOR 1 (TCF-1), A T-CELL PRODUCT THAT INDUCES MURINE THYMOCYTE DIFFERENTIATION. Immunobiology 175 (4), S. 313-314. Volltext nicht vorhanden.

Falk, W., Kyewski, B., Männel, Daniela N. und Krammer, P. H. (1987) INTERLEUKIN-1 INDUCED GROWTH OF DOUBLE-NEGATIVE (L3T4- AND LYT2-) IMMATURE MOUSE THYMOCYTES IS INITIATED BY INDUCING THE SYNTHESIS OF INTERLEUKIN-2 RECEPTOR MESSENGER-RNA. Immunobiology 175 (4), S. 264. Volltext nicht vorhanden.

Northoff, H., Andus, T., Tranthi, T. A., Flegel, W. A., Bauer, J., Männel, Daniela N. und Heinrich, P. C. (1987) TUMOR-NECROSIS-FACTOR (TNF), INTERFERON-ALPHA, INTERFERON-GAMMA AND INTERFERON-BETA-1 DO NOT EXHIBIT HEPATOCYTE STIMULATING (HSF) ACTIVITY. Immunobiology 175 (4), S. 315-316. Volltext nicht vorhanden.

Urbaschek, R., Männel, Daniela N. und Urbaschek, B. (1987) MEDIATION OF BENEFICIAL-EFFECTS OF ENDOTOXIN BY TUMOR-NECROSIS-FACTOR. Immunobiology 175 (1-2), S. 39. Volltext nicht vorhanden.

Männel, Daniela N. und Urbaschek, R. (1987) BIOLOGICAL-ACTIVITY OF TUMOR-NECROSIS-FACTOR (TNF) IN MICE. European Journal of Pediatrics 146 (3), S. 340. Volltext nicht vorhanden.

Männel, Daniela N. und Urbaschek, R. (1987) TUMOR-NECROSIS-FACTOR - A MEDIATOR OF ENDOTOXIC-SHOCK. Journal of clinical chemistry and clinical biochemistry 25 (4), S. 228-229. Volltext nicht vorhanden.

Hensel, G., Männel, Daniela N., Pfizenmaier, K. und Krönke, M. (1987) Autocrine stimulation of TNF-alpha mRNA expression in HL-60 cells. Lymphokine research 6 (2), S. 119-125. Volltext nicht vorhanden.

Andus, T., Heinrich, P. C., Bauer, J., Tran-Thi, T. A., Decker, K., Männel, Daniela N. und Northoff, H. (1987) Discrimination of hepatocyte-stimulating activity from human recombinant tumor necrosis factor alpha. European journal of immunology 17 (8), S. 1193-1197.

Falk, W., Kyewski, B., Männel, Daniela N. und Krammer, P. H. (1987) GROWTH OF DOUBLE-NEGATIVE (L3T4 AND LYT2) MOUSE THYMOCYTES IS INITIATED BY THE COMBINED ACTION OF INTERLEUKIN-1 (IL-1) AND INTERLEUKIN-2 (IL-2). Lymphokine research 6 (1), U77. Volltext nicht vorhanden.

Esparza, I., Männel, Daniela N., Ruppel, A., Falk, W. und Krammer, P. H. (1987) INTERFERON-Y (IFN-Y) AND LYMPHOTOXIN (LT) OR TUMOR-NECROSIS-FACTOR (TNF) SYNERGIZE TO ACTIVATE MACROPHAGES FOR TUMORICIDAL AND SCHISTOSOMULICIDAL FUNCTIONS. Lymphokine research 6 (1), U129. Volltext nicht vorhanden.

Esparza, I., Männel, Daniela N., Ruppel, A., Falk, Werner und Krammer, P. H. (1987) Interferon gamma and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni. The Journal of experimental medicine 166 (2), S. 589-594.

Männel, Daniela N., Falk, W. und Northoff, H. (1987) THERMOREGULATORY ACTIVITY OF TUMOR-NECROSIS-FACTOR INDEPENDENT OF MACROPHAGE IL1 PRODUCTION. Lymphokine Research 6 (1), U99. Volltext nicht vorhanden.

Urbaschek, R., Männel, Daniela N. und Urbaschek, B. (1987) Tumor necrosis factor induced stimulation of granulopoiesis and radioprotection. Lymphokine research 6 (3), S. 179-186. Volltext nicht vorhanden.

Bauss, F., Dröge, W. und Männel, Daniela N. (1987) Tumor necrosis factor mediates endotoxic effects in mice. Infection and immunity 55 (7), S. 1622-1625.

Männel, Daniela N., Northoff, H., Bauss, F. und Falk, Werner (1987) Tumor necrosis factor: a cytokine involved in toxic effects of endotoxin. Reviews of infectious diseases 9 Suppl 5, S602-S606. Volltext nicht vorhanden.

Esparza, I., Männel, Daniela N., Ruppel, A., Falk, W. und Krammer, P. H. (1986) GAMMA-INTERFERON (IFN-GAMMA) AND LYMPHOTOXIN OR TUMOR-NECROSIS-FACTOR SYNERGIZE TO ACTIVATE MACROPHAGES FOR TUMORICIDAL AND SCHISTOSOMULICIDAL FUNCTIONS. Immunobiology 173 (2-5), S. 244. Volltext nicht vorhanden.

Hensel, G., Männel, Daniela N., Hofsommer, A., Pfizenmaier, K. und Kronke, M. (1986) RECOMBINANT TUMOR-NECROSIS-FACTOR (RTNF) INDUCES TNF MESSENGER-RNA ACCUMULATION IN HL60 CELLS. Immunobiology 173 (2-5), S. 120. Volltext nicht vorhanden.

Bauss, F. und Männel, Daniela N. (1986) TUMOR NECROSIS FACTOR-INDUCED HYPERREACTIVITY AND TOLERANCE TO HYPOTHERMIA IN MICE. Immunobiology 173 (2-5), S. 112. Volltext nicht vorhanden.

Männel, Daniela N. (1986) Biological aspects of tumor necrosis factor. Immunobiology 172 (3-5), S. 283-290.

Männel, Daniela N., Dröge, W. und Falk, Werner (1986) REGULATION OF T-CELL FUNCTION WITH MONOCLONAL ANTI-THY-1 ANTIBODIES. Journal of Cellular Biochemistry (Suppl.), S. 79. Volltext nicht vorhanden.

Männel, Daniela N., Droge, W. und Falk, W. (1985) BIOLOGICAL EFFECTS OF MONOCLONAL-ANTIBODIES DIRECTED AGAINST A MURINE T-CELL SURFACE PROTEIN. Immunobiology 170 (1-2), S. 57-58. Volltext nicht vorhanden.

Daum, L., Falk, W., Dröge, W. und Männel, Daniela N. (1984) DOES THE DIFFERENTIATION OF CYTO-TOXIC LYMPHOCYTES-T REQUIRE IFN-GAMMA? Immunobiology 168 (1-2), S. 30. Volltext nicht vorhanden.

Männel, Daniela N. und Falk, W. (1984) INDUCTION OF IL2 RESPONSIVENESS BY A T-CELL DERIVED LYMPHOKINE. Immunobiology 167 (1-3), S. 261. Volltext nicht vorhanden.

Männel, Daniela N., Falk, Werner, Herrmann, T., Osawa, H. und Diamantstein, T. (1984) INDUCTION OF T-CELL DIFFERENTIATION BY A SOLUBLE MEDIATOR. Immunobiology 168 (1-2), S. 7. Volltext nicht vorhanden.

Orbachyliruka, E., Männel, Daniela N., Dröge, W. und Falk, W. (1984) T-CELL CYTO-TOXICITY INDUCING FACTOR-I (TCF-1) IS A PRODUCT OF ACTIVATED T-CELLS. Immunobiology 168 (1-2), S. 35-36. Volltext nicht vorhanden.

Männel, Daniela N. und Falk, W. (1984) T-CELL CYTO-TOXICITY INDUCING FACTOR-I (TCF1) IS A T-CELL PRODUCT THAT INDUCES THYMOCYTE DIFFERENTIATION. Lymphokine research 3 (4), S. 257. Volltext nicht vorhanden.

Männel, Daniela N., Falk, W. und Dröge, W. (1983) EFFECTS OF LYMPHOKINES ON THE SPECIFICITY OF CYTO-TOXIC LYMPHOCYTE-T RESPONSES. Immunobiology 165 (3-4), S. 314. Volltext nicht vorhanden.

Männel, Daniela N. und Falk, Werner (1983) Interferon-gamma is required in activation of macrophages for tumor cytotoxicity. Cellular immunology 79 (2), S. 396-402.

Falk, W., Männel, Daniela N. und Dröge, W. (1982) A MINIMUM OF 3 DIFFERENT LYMPHOKINES IS REQUIRED FOR THE GENERATION OF CYTO-TOXIC T-CELL RESPONSES. Immunobiology 162 (4-5), S. 348. Volltext nicht vorhanden.

Männel, Daniela N., De Maeyer, E., Kemler, R., Cachard, A. und De Maeyer-Guignard, J. (1982) A rat monoclonal antibody against mouse alpha and beta interferon of all molecular weight species. Nature (London) 296 (5858), S. 664-665.

Männel, Daniela N., Falk, W. und Droege, W. (1982) GENERATION OF CYTO-TOXIC T-CELL RESPONSES REQUIRES AT LEAST 2 EARLY ACTING HELPER FACTORS AND ONE LATE ACTING HELPER FACTOR. Immunobiology 162 (4-5), S. 387. Volltext nicht vorhanden.

Männel, Daniela N. (1982) Possible role of endotoxin in mediating host resistance. Klinische Wochenschrift 60 (14), S. 752-753.

Männel, Daniela N. und Falk, Werner (1982) Requirement for γ-interferon in activation of macrophages for tumor cytotoxicity. Cellular Immunology 70 (2), S. 389. Volltext nicht vorhanden.

Männel, Daniela N., Meltzer, M. S. und Mergenhagen, S. E. (1980) Generation and characterization of a lipopolysaccharide-induced and serum-derived cytotoxic factor for tumor cells. Infection and immunity 28 (1), S. 204-211.

Männel, Daniela N. (1980) SOLUBLE CYTO-TOXIC FACTOR FROM MURINE MACROPHAGES. Federation Proceedings 39 (3), S. 451. Volltext nicht vorhanden.

Männel, Daniela N., Farrar, J. J. und Mergenhagen, S. E. (1980) Separation of a serum-derived tumoricidal factor from a helper factor for plaque-forming cells. Journal of immunology 124 (3), S. 1106-1110.

Männel, Daniela N., Farrar, J. J. und Mergenhagen, S. E. (1979) Characterization of a cytotoxic serum factor from mice - mode of production, specificity and physicochemical properties. Federation proceedings 38 (3), S. 1455. Volltext nicht vorhanden.

Männel, Daniela N., Mäkelä, P. H. und Mayer, H. (1978) Enterobacterial common antigen in mutant strains of Salmonella. Journal of bacteriology 135 (2), S. 348-353.

Männel, Daniela N. und Mayer, H. (1978) Isolation and chemical characterization of the enterobacterial common antigen. European journal of biochemistry: the FEBS Journal 86 (2), S. 361-370.

Männel, Daniela N. und Mayer, H. (1978) Serological and immunological properties of isolated enterobacterial common antigen. European journal of biochemistry: the FEBS Journal 86 (2), S. 371-379.

Schmidt, G., Männel, Daniela N., Mayer, H., Whang, H. Y. und Neter, E. (1976) Role of a lipopolysaccharide gene for immunogenicity of the enterobacterial common antigen. Journal of bacteriology 126 (2), S. 579-586.

Buchkapitel

Männel, Daniela N. und Falk, Werner (1983) Requirement of g-interferon in activation of macrophages for tumour cytotoxicity. In: Oppenheim, J. J. und Cohen, S., (eds.) Interleukins, Lymphokines and Cytokines: Proceedings of the Third International Lymphokine Workshop. Academic Press, New York, S. 287-290. ISBN 0125275404; 978-0125275408. Volltext nicht vorhanden.

Hochschulschrift

Männel, Daniela N. (1985) Untersuchungen über die Struktur-Wirkungsmechanismen bei der Endotoxin-verursachten Tumornekrose. Habilitation, Heidelberg, Univ.. Volltext nicht vorhanden.

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