Anzahl der Einträge: 145.
2024
Rupp, Kevin,
Schill, Rudolf ,
Süskind, Jonas,
Georg, Peter,
Klever, Maren,
Lösch, Andreas,
Grasedyck, Lars,
Wettig, Tilo und
Spang, Rainer
(2024)
Differentiated uniformization: a new method for inferring Markov chains on combinatorial state spaces including stochastic epidemic models.
Computational Statistics.
Schill, Rudolf ,
Klever, Maren,
Rupp, Kevin,
Hu, Y. Linda,
Lösch, Andreas,
Georg, Peter,
Pfahler, Simon,
Vocht, Stefan,
Hansch, Stefan,
Wettig, Tilo ,
Grasedyck, Lars und
Spang, Rainer
(2024)
Reconstructing Disease Histories in Huge Discrete State Spaces.
KI - Künstliche Intelligenz.
2023
Schill, Rudolf,
Klever, Maren,
Lösch, Andreas,
Hu, Y. Linda ,
Vocht, Stefan,
Rupp, Kevin,
Grasedyck, Lars,
Spang, Rainer und
Beerenwinkel, Niko
(2023)
Overcoming Observation Bias for Cancer Progression Modeling.
bioRxiv.
(Eingereicht)
Leich, E.,
Brodtkorb, Marianne,
Schmidt, T.,
Altenbuchinger, Michael,
Lingjærde, Ole Christian,
Lockmer, S.,
Holte, H.,
Nedeva, T.,
Grieb, T.,
Sander, B.,
Sundström, C.,
Spang, Rainer,
Kimby, E. und
Rosenwald, A.
(2023)
Gene expression and copy number profiling of follicular lymphoma biopsies from patients treated with first-line rituximab without chemotherapy.
Leukemia & lymphoma, S. 1-11.
Volltext nicht vorhanden.
Buck, Lena,
Schmidt, Tobias,
Feist, Maren,
Schwarzfischer, Philipp,
Kube, Dieter,
Oefner, Peter J. ,
Zacharias, Helena U.,
Altenbuchinger, Michael ,
Dettmer, Katja ,
Gronwald, Wolfram und
Spang, Rainer
(2023)
Anomaly detection in mixed high dimensional molecular data.
Bioinformatics 39 (8), btad501.
Rösler, Wiebke,
Altenbuchinger, Michael,
Baeßler, Bettina,
Beissbarth, Tim,
Beutel, Gernot,
Bock, Robert,
von Bubnoff, Nikolas,
Eckardt, Jan-Niklas,
Foersch, Sebastian,
Loeffler, Chiara M L,
Middeke, Jan Moritz,
Mueller, Martha-Lena,
Oellerich, Thomas,
Risse, Benjamin,
Scherag, André,
Schliemann, Christoph,
Scholz, Markus,
Spang, Rainer ,
Thielscher, Christian,
Tsoukakis, Ioannis und
Kather, Jakob Nikolas
(2023)
An overview and a roadmap for artificial intelligence in hematology and oncology.
Journal of cancer research and clinical oncology.
2022
Georg, Peter,
Grasedyck, Lars,
Klever, Maren,
Schill, Rudolf ,
Spang, Rainer und
Wettig, Tilo
(2022)
Low-rank tensor methods for Markov chains with applications to tumor progression models.
Journal of Mathematical Biology 86 (7).
Sorrentino, Antonio,
Menevse, Ayse Nur ,
Michels, Tillmann,
Volpin, Valentina,
Durst, Franziska Christine,
Sax, Julian,
Xydia, Maria,
Hussein, Abir,
Stamova, Slava,
Spoerl, Steffen,
Heuschneider, Nicole,
Muehlbauer, Jasmin,
Jeltsch, Katharina Marlene,
Rathinasamy, Anchana,
Werner-Klein, Melanie,
Breinig, Marco,
Mikietyn, Damian,
Kohler, Christian,
Poschke, Isabel,
Purr, Sabrina,
Reidell, Olivia,
Martins Freire, Catarina,
Offringa, Rienk,
Gebhard, Claudia,
Spang, Rainer,
Rehli, Michael,
Boutros, Michael ,
Schmidl, Christian ,
Khandelwal, Nisit und
Beckhove, Philipp
(2022)
Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.
Journal for immunotherapy of cancer 10 (5), e004258.
Hassel, Jessica C.,
Schank, Timo E.,
Smetak, Heiko,
Mühlbauer, Jasmin,
Salzmann, Martin,
Machiraju, Devayani,
Menzer, Christian,
Lang, Kristin,
König, Laila,
Haefner, Matthias F.,
Hülsmeyer, Ingrid,
Kohler, Christian ,
Spang, Rainer ,
Enk, Alexander,
Debus, Jürgen und
Beckhove, Philipp
(2022)
Evaluation of radio-immunotherapy sequence on immunological responses and clinical outcomes in patients with melanoma brain metastases (ELEKTRA).
Oncoimmunology 11 (1), S. 2066609.
Schrod, Stefan,
Schäfer, Andreas,
Solbrig, Stefan,
Lohmayer, Robert,
Gronwald, Wolfram ,
Oefner, Peter J. ,
Beißbarth, Tim,
Spang, Rainer ,
Zacharias, Helena U. und
Altenbuchinger, Michael
(2022)
BITES: Balanced Individual Treatment Effect for Survival data.
arXiv.
(Eingereicht)
2021
Siska, Peter J.,
Decking, Sonja-Maria,
Babl, Nathalie,
Matos, Carina,
Bruss, Christina,
Singer, Katrin,
Klitzke, Jana,
Schön, Marian,
Simeth, Jakob ,
Köstler, Josef,
Siegmund, Heiko,
Ugele, Ines,
Paulus, Michael,
Dietl, Alexander,
Kolodova, Kristina,
Steines, Louisa ,
Freitag, Katharina,
Peuker, Alice,
Schönhammer, Gabriele,
Raithel, Johanna,
Graf, Bernhard,
Geismann, Florian,
Lubnow, Matthias,
Mack, Matthias,
Hau, Peter,
Bohr, Christopher,
Burkhardt, Ralph ,
Gessner, Andre,
Salzberger, Bernd,
Wagner, Ralf,
Hanses, Frank,
Hitzenbichler, Florian,
Heudobler, Daniel,
Lüke, Florian,
Pukrop, Tobias,
Herr, Wolfgang,
Wolff, Daniel,
Spang, Rainer,
Poeck, Hendrik,
Hoffmann, Petra,
Jantsch, Jonathan,
Brochhausen, Christoph,
Lunz, Dirk,
Rehli, Michael,
Kreutz, Marina und
Renner, Kathrin
(2021)
Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone.
Journal of Clinical Investigation 131 (22), e148225.
Zugang zum Volltext eingeschränkt.
Richter, Julia ,
John, Katharina,
Staiger, Annette M.,
Rosenwald, Andreas,
Kurz, Katrin,
Michgehl, Ulf,
Ott, German,
Franzenburg, Sören,
Kohler, Christian ,
Finger, Jasmin,
Oschlies, Ilske,
Paul, Ulrike,
Siebert, Reiner,
Spang, Rainer ,
Burkhardt, Birgit und
Klapper, Wolfram
(2021)
Epstein-Barr virus status of sporadic Burkitt lymphoma is associated with patient age and mutational features.
British journal of haematology 196 (3), S. 681-689.
Croci, G. A.,
Au-Yeung, R. K. H.,
Reinke, S.,
Staiger, A. M.,
Koch, K.,
Oschlies, I.,
Richter, J.,
Poeschel, V.,
Held, G.,
Loeffler, M.,
Trümper, L.,
Rosenwald, A.,
Ott, G.,
Spang, Rainer,
Altmann, B.,
Ziepert, M. und
Klapper, W.
(2021)
SPARC-positive macrophages are the superior prognostic factor in the microenvironment of diffuse large B-cell lymphoma and independent of MYC rearrangement and double-/triple-hit status.
Annals of Oncology.
Volltext nicht vorhanden.
Jachimowicz, Ron D.,
Klapper, Wolfram,
Glehr, Gunther ,
Müller, Horst,
Haverkamp, Heinz,
Thorns, Christoph,
Hansmann, Martin Leo,
Möller, Peter,
Stein, Harald,
Rehberg, Thorsten,
von Tresckow, Bastian,
Reinhardt, H. C.,
Borchmann, Peter,
Chan, Fong Chun,
Spang, Rainer,
Scott, David W.,
Engert, Andreas,
Steidl, Christian,
Altenbuchinger, Michael und
Rosenwald, Andreas
(2021)
Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP.
Leukemia.
Linck-Paulus, Lisa ,
Lämmerhirt, Lisa,
Völler, Daniel,
Meyer, Katharina,
Engelmann, Julia C. ,
Spang, Rainer,
Eichner, Norbert,
Meister, Gunter,
Kuphal, Silke und
Bosserhoff, Anja Katrin
(2021)
Learning from Embryogenesis—A Comparative Expression Analysis in Melanoblast Differentiation and Tumorigenesis Reveals miRNAs Driving Melanoma Development.
Journal of Clinical Medicine 10 (11), S. 2259.
Nordmo, Carmen,
Glehr, Gunther,
Altenbuchinger, Michael,
Spang, Rainer,
Ziepert, Marita,
Horn, Heike,
Staiger, Annette M.,
Ott, German,
Schmitz, Norbert,
Held, Gerhard,
Einsele, Hermann,
Topp, Max,
Rosenwald, Andreas und
Rauert-Wunderlich, Hilka
(2021)
Identification of a miRNA based model to detect prognostic subgroups in patients with aggressive B-cell lymphoma.
Leukemia & Lymphoma 62 (5), S. 1107-1115.
Volltext nicht vorhanden.
Hutchinson, James A. ,
Kronenberg, Katharina,
Riquelme, Paloma,
Wenzel, Jürgen J. ,
Glehr, Gunther ,
Schilling, Hannah-Lou ,
Zeman, Florian,
Evert, Katja,
Schmiedel, Martin,
Mickler, Marion,
Drexler, Konstantin,
Bitterer, Florian,
Cordero, Laura,
Beyer, Lukas Philipp,
Bach, Christian,
Koestler, Josef,
Burkhardt, Ralph ,
Schlitt, Hans J.,
Hellwig, Dirk,
Werner, Jens M.,
Spang, Rainer,
Schmidt, Barbara,
Geissler, Edward K. und
Haferkamp, Sebastian
(2021)
Virus-specific memory T cell responses unmasked by immune checkpoint blockade cause hepatitis.
Nature Communications 12, S. 1439.
2020
Reinders, Jörg,
Altenbuchinger, Michael,
Limm, Katharina ,
Schwarzfischer, Philipp,
Scheidt, Tamara,
Strasser, Lisa,
Richter, Julia,
Szczepanowski, Monika,
Huber, Christian G. ,
Klapper, Wolfram,
Spang, Rainer und
Oefner, Peter J.
(2020)
Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue.
Scientific Reports 10 (7876), S. 1-11.
Schoen, Marian,
Simeth, Jakob ,
Heinrich, Paul,
Goertler, F.,
Solbrig, Stefan,
Wettig, Tilo,
Oefner, Peter J.,
Altenbuchinger, Michael und
Spang, Rainer
(2020)
DTD: An R Package for Digital Tissue Deconvolution.
J. Comput. Biol..
Volltext nicht vorhanden.
Goertler, Franziska,
Schoen, Marian,
Simeth, Jakob ,
Solbrig, Stefan,
Wettig, Tilo,
Oefner, Peter J.,
Spang, Rainer und
Altenbuchinger, Michael
(2020)
Loss-Function Learning for Digital Tissue Deconvolution.
J. Comput. Biol..
Volltext nicht vorhanden.
Minderjahn, Julia,
Schmidt, Andreas,
Fuchs, Andreas ,
Schill, Rudolf,
Raithel, Johanna,
Babina, Magda ,
Schmidl, C. ,
Gebhard, Claudia,
Schmidhofer, Sandra,
Mendes, Karina ,
Ratermann, Anna,
Glatz, Dagmar,
Nützel, Margit,
Edinger, Matthias,
Hoffmann, Petra,
Spang, Rainer ,
Längst, Gernot,
Imhof, A. und
Rehli, Michael
(2020)
Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1.
Nat Commun 11, S. 402.
2019
Arlt, A.,
von Bonin, F.,
Rehberg, Thorsten,
Perez-Rubio, Paula,
Engelmann, Julia C. ,
Limm, Katharina ,
Reinke, S.,
Dullin, C.,
Sun, Xueni,
Specht, R.,
Maulhardt, M.,
Linke, F. ,
Bunt, G.,
Klapper, W.,
Vockerodt, M.,
Wilting, J.,
Pukrop, T.,
Dettmer, Katja,
Gronwald, Wolfram,
Oefner, Peter J.,
Spang, Rainer und
Kube, D.
(2019)
High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination.
Mol Oncol.
Volltext nicht vorhanden.
Altenbuchinger, Michael,
Zacharias, Helena,
Solbrig, S.,
Schaefer, Andreas,
Buyukozkan, M.,
Schultheiss, U. T. ,
Kotsis, F.,
Köttgen, Anna,
Spang, Rainer,
Oefner, Peter J.,
Krumsiek, J. und
Gronwald, Wolfram
(2019)
A multi-source data integration approach reveals novel associations between metabolites and renal outcomes in the German Chronic Kidney Disease study.
Scientific Reports 9 (1), S. 13954.
Staiger, A. M.,
Altenbuchinger, Michael,
Ziepert, M.,
Kohler, Christian,
Horn, H.,
Huttner, Michael ,
Huttl, K. S.,
Glehr, Gunther ,
Klapper, W.,
Szczepanowski, M.,
Richter, J.,
Stein, H.,
Feller, A. C.,
Moller, P.,
Hansmann, M. L.,
Poeschel, V.,
Held, G.,
Loeffler, M.,
Schmitz, N.,
Trumper, L.,
Pukrop, T.,
Rosenwald, A.,
Ott, G.,
Spang, Rainer ,
Emed Demonstrator Project, und
German High Grade Non-Hodgkin’s Lymphoma Study Group (DSHNHL),
(2019)
A novel lymphoma-associated macrophage interaction signature (LAMIS) provides robust risk prognostication in diffuse large B-cell lymphoma clinical trial cohorts of the DSHNHL.
Leukemia.
Volltext nicht vorhanden.
Wagner, M.,
Hansel, R.,
Reinke, S.,
Richter, J.,
Altenbuchinger, Michael,
Braumann, U. D.,
Spang, Rainer,
Loffler, M. und
Klapper, W.
(2019)
Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach.
Biol Proced Online 21, S. 13.
Itzel, T.,
Spang, Rainer,
Maass, T.,
Munker, S.,
Roessler, S. ,
Ebert, M. P.,
Schlitt, Hans J.,
Herr, Wolfgang,
Evert, Matthias und
Teufel, A.
(2019)
Random gene sets in predicting survival of patients with hepatocellular carcinoma.
J. Mol. Med..
Volltext nicht vorhanden.
Kleo, K.,
Dimitrova, L.,
Oker, E.,
Tomaszewski, N.,
Berg, E.,
Taruttis, Franziska,
Engelmann, Julia C. ,
Schwarzfischer, Philipp,
Reinders, Jörg ,
Spang, Rainer,
Gronwald, Wolfram ,
Oefner, Peter J. und
Hummel, Michael
(2019)
Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma.
BMC Cancer 19 (1), S. 322.
Zacharias, Helena,
Altenbuchinger, Michael,
Schultheiss, U. T.,
Samol, Claudia,
Kotsis, F.,
Poguntke, I.,
Sekula, P. ,
Krumsiek, J.,
Köttgen, Anna,
Spang, Rainer,
Oefner, Peter J. und
Gronwald, Wolfram
(2019)
A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease.
Journal of Proteome Research.
Volltext nicht vorhanden.
Schnitter, A.,
Kohler, Christian ,
Reddemann, K.,
Reinke, S.,
Thorns, C.,
Fend, F.,
Federmann, B.,
Moeller, P.,
Szczepanowski, Monika,
Spang, Rainer und
Klapper, Wolfram
(2019)
Therapeutic targets and microenvironment in sequential biopsies of classical Hodgkin lymphoma at diagnosis and relapse.
Journal of Hematopathology 12 (1), S. 11-17.
Ziegler, Christian,
Graf, Johannes,
Faderl, Stefan,
Schedlbauer, Jessica,
Strieder, Nicholas,
Förstl, Bianca,
Spang, Rainer,
Bruckmann, Astrid,
Merkl, Rainer ,
Hombach, Sonja und
Kretz, Markus
(2019)
The long non-coding RNA LINC00941 and SPRR5 are novel regulators of human epidermal homeostasis.
EMBO Rep., e46612.
Volltext nicht vorhanden.
2018
Heinrich, Paul,
Kohler, Christian ,
Ellmann, Lisa,
Kuerner, Paul,
Spang, Rainer,
Oefner, Peter J. und
Dettmer, Katja
(2018)
Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR.
Scientific Reports 8 (17910), S. 1-10.
Fröhlich, Holger,
Balling, R. ,
Beerenwinkel, N.,
Kohlbacher, O.,
Kumar, S.,
Lengauer, T.,
Maathuis, M. H.,
Moreau, Y.,
Murphy, S. A.,
Przytycka, T. M. ,
Rebhan, M.,
Rost, H. ,
Schuppert, A. ,
Schwab, M.,
Spang, Rainer,
Stekhoven, D.,
Sun, J.,
Weber, A.,
Ziemek, D. und
Zupan, B.
(2018)
From hype to reality: data science enabling personalized medicine.
BMC Med 16 (1), S. 150.
Cho, H.,
Berger, B.,
Peng, J.,
Galitzine, C.,
Vitek, O.,
Beltran, P. M. J.,
Cristea, I. M.,
Görtler, Franziska,
Solbrig, Stefan,
Wettig, Tilo,
Oefner, Peter J. ,
Spang, Rainer,
Altenbuchinger, Michael,
Basso, R. S.,
Hochbaum, D.,
Vandin, F.,
Silverbush, D.,
Cristea, S.,
Yanovich, G.,
Geiger, T.,
Beerenwinkel, N.,
Sharan, R.,
Zhou, Z.,
Luhmann, N.,
Alikhan, N. F. und
Achtman, M.
(2018)
Principles of Systems Biology, No. 31.
Cell Syst 7 (2), S. 133-135.
Volltext nicht vorhanden.
Reinke, Sarah ,
Richter, Julia,
Fend, Falko,
Feller, Alfred,
Hansmann, Martin-Leo,
Hüttl, Katrin,
Oschlies, Ilske,
Ott, German,
Möller, Peter,
Rosenwald, Andreas,
Stein, Harald,
Altenbuchinger, Michael,
Spang, Rainer und
Klapper, Wolfram
(2018)
Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma—a feasibility study using full slide staining.
Virchows Archiv.
Volltext nicht vorhanden.
Görtler, Franziska,
Solbrig, Stefan,
Wettig, Tilo,
Oefner, Peter J. ,
Spang, Rainer und
Altenbuchinger, Michael
(2018)
Loss-function learning for digital tissue deconvolution.
In:
Raphael, Benjamin J., (ed.)
Research in Computational Molecular Biology : 22nd Annual International Conference, RECOMB 2018, Paris, France, April 21-24, 2018, Proceedings.
Lecture Notes in Computer Science, 10812.
Springer International Publishing, Cham, S. 75-89.
ISBN 978-3-319-89929-9 ; 978-3-319-89928-2.
Volltext nicht vorhanden.
Feist, M.,
Schwarzfischer, Philipp,
Heinrich, Paul,
Sun, Xueni,
Kemper, J.,
von Bonin, F.,
Perez-Rubio, Paula,
Taruttis, Franziska,
Rehberg, Thorsten,
Dettmer, Katja,
Gronwald, Wolfram,
Reinders, Jörg,
Engelmann, Julia C. ,
Dudek, J.,
Klapper, W.,
Trumper, L.,
Spang, Rainer,
Oefner, Peter J. und
Kube, D.
(2018)
Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression.
Nat Commun 9 (1), S. 1514.
Horn, H.,
Kohler, Christian,
Witzig, R.,
Kreuz, M. ,
Leich, E.,
Klapper, W.,
Hummel, M.,
Loeffler, M.,
Trumper, L.,
Spang, Rainer,
Rosenwald, A. und
Ott, G.
(2018)
Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2.
Haematologica.
Volltext nicht vorhanden.
Riquelme, Paloma ,
Haarer, Jan,
Kammler, Anja,
Walter, Lisa ,
Tomiuk, Stefan,
Ahrens, Norbert ,
Wege, Anja K. ,
Goecze, Ivan,
Zecher, Daniel,
Banas, Bernhard ,
Spang, Rainer ,
Fändrich, Fred,
Lutz, Manfred B.,
Sawitzki, Birgit,
Schlitt, Hans J. ,
Ochando, Jordi ,
Geissler, Edward K. und
Hutchinson, James A.
(2018)
TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity.
Nature Communications 9 (2858), S. 1-18.
2017
Paul, U.,
Richter, J.,
Stuhlmann-Laiesz, C.,
Kreuz, M. ,
Nagel, I.,
Horn, H.,
Staiger, A. M.,
Aukema, S. M.,
Hummel, M.,
Ott, G.,
Spang, Rainer,
Rosenwald, A.,
Feller, A. C.,
Cogliatti, S.,
Stein, H.,
Hansmann, M. L.,
Moller, P.,
Szczepanowski, M.,
Burkhardt, B.,
Pfreundschuh, M.,
Schmitz, N.,
Loeffler, M.,
Trumper, L.,
Siebert, R. und
Klapper, W.
(2017)
Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC.
Leuk. Lymphoma, S. 1-9.
Volltext nicht vorhanden.
Zacharias, Helena,
Rehberg, Thorsten,
Mehrl, S.,
Richtmann, D.,
Wettig, Tilo,
Oefner, Peter J.,
Spang, Rainer,
Gronwald, Wolfram und
Altenbuchinger, Michael
(2017)
Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints.
J. Proteome Res..
Volltext nicht vorhanden.
Altenbuchinger, Michael,
Schwarzfischer, Philipp,
Rehberg, Thorsten,
Reinders, Jörg ,
Kohler, Christian ,
Gronwald, Wolfram ,
Richter, J.,
Szczepanowski, M.,
Masqué-Soler, N.,
Klapper, W.,
Oefner, Peter J. und
Spang, Rainer
(2017)
Molecular signatures that can be transferred across different omics platforms.
Bioinformatics 33 (14), i333-i340.
Volltext nicht vorhanden.
Oschlies, I.,
Kohler, Christian,
Szczepanowski, Monika,
Koch, K.,
Gontarewicz, A.,
Metze, D.,
Hillen, U.,
Richter, J.,
Spang, Rainer und
Klapper, W.
(2017)
Spindle-cell variant of primary cutaneous follicle center B-cell lymphomas are germinal center B-cell lymphomas by gene expression profiling using formalin-fixed paraffin embedded specimen.
J Invest Dermatol.
Volltext nicht vorhanden.
Szczepanowski, M.,
Lange, J.,
Kohler, Christian,
Masque-Soler, N.,
Zimmermann, M.,
Aukema, S. M.,
Altenbuchinger, Michael,
Rehberg, Thorsten,
Mahn, F.,
Siebert, R.,
Spang, Rainer,
Burkhardt, B. und
Klapper, W.
(2017)
Cell-of-origin classification by gene expression and MYC-rearrangements in diffuse large B-cell lymphoma of children and adolescents.
Br. J. Haematol..
Volltext nicht vorhanden.
Rohde, M.,
Bonn, B. R.,
Zimmermann, M.,
Lange, J.,
Moricke, A.,
Klapper, W.,
Oschlies, I.,
Szczepanowski, M.,
Nagel, I.,
Schrappe, M.,
Loeffler, M.,
Siebert, R.,
Reiter, A.,
Burkhardt, B.,
Altenbuchinger, Michael,
Dettmer-Wilde, Katja,
Engelmann, Julia C. ,
Gronwald, Wolfram ,
Oefner, Peter J. ,
Schwarzfischer, Philipp,
Taruttis, Franziska und
Spang, Rainer
(2017)
Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt-Münster protocols.
Haematologica 102 (6), S. 1091-1098.
Volltext nicht vorhanden.
Feist, M.,
Kemper, J.,
Taruttis, Franziska,
Rehberg, Thorsten,
Engelmann, Julia C. ,
Gronwald, Wolfram,
Hummel, Michael,
Spang, Rainer und
Kube, Dieter
(2017)
Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis.
International Journal of Cancer: Int. J. Cancer.
Volltext nicht vorhanden.
Schwarzfischer, Philipp,
Reinders, Jörg,
Dettmer, Katja ,
Kleo, K.,
Dimitrova, L.,
Hummel, M.,
Feist, M.,
Kube, D.,
Szczepanowski, M.,
Klapper, W.,
Taruttis, Franziska,
Engelmann, Julia C. ,
Spang, Rainer,
Gronwald, Wolfram und
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Hansmann, Martin-Leo,
Hummel, Michael,
Kestler, Hans A.,
Klapper, Wolfram,
Kreuz, Markus,
Lenze, Dido,
Loeffler, Markus,
Möller, Peter,
Müller-Hermelink, Hans-Konrad,
Ott, German,
Rosolowski, Maciej,
Rosenwald, Andreas,
Ruf, Sandra,
Siebert, Reiner,
Spang, Rainer,
Stein, Harald,
Truemper, Lorenz,
Lichter, Peter,
Bentz, Martin und
Wessendorf, Swen
(2009)
Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status.
Genes, Chromosomes and Cancer 48 (1), S. 39-54.
Volltext nicht vorhanden.
2008
Fröhlich, H.,
Beissbarth, T.,
Tresch, A.,
Kostka, D.,
Jacob, Juby,
Spang, Rainer und
Markowetz, F.
(2008)
Analyzing gene perturbation screens with nested effects models in R and bioconductor.
Bioinformatics 24 (21), S. 2549-2550.
Volltext nicht vorhanden.
Bentink, Stefan,
Wessendorf, S.,
Schwaenen, C.,
Rosolowski, M.,
Klapper, W.,
Rosenwald, A.,
Ott, G.,
Banham, A. H.,
Berger, H.,
Feller, A. C.,
Hansmann, M. L.,
Hasenclever, D.,
Hummel, M.,
Lenze, D.,
Möller, P.,
Stuerzenhofecker, B.,
Loeffler, M.,
Truemper, L.,
Stein, H.,
Siebert, R. und
Spang, Rainer
(2008)
Pathway activation patterns in diffuse large B-cell lymphomas.
Leukemia 22 (9), S. 1746-1754.
Volltext nicht vorhanden.
Klapper, W.,
Szczepanowski, M.,
Burkhardt, B.,
Berger, H.,
Rosolowski, M.,
Bentink, Stefan,
Schwaenen, C.,
Wessendorf, S.,
Spang, Rainer,
Moller, P.,
Hansmann, M. L.,
Bernd, H. W.,
Ott, G.,
Hummel, M.,
Stein, H.,
Loeffler, M.,
Trumper, L.,
Zimmermann, M.,
Reiter, A. und
Siebert, R.
(2008)
Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials.
Blood 112 (4), S. 1374-1381.
Volltext nicht vorhanden.
Dierlamm, J.,
Murga Penas, E. M.,
Bentink, Stefan,
Wessendorf, S.,
Berger, H.,
Hummel, M.,
Klapper, W.,
Lenze, D.,
Rosenwald, A.,
Haralambieva, E.,
Ott, G.,
Cogliatti, S. B.,
Möller, Peter,
Schwaenen, C.,
Stein, H.,
Löffler, M.,
Spang, Rainer,
Trumper, L. und
Siebert, Reiner
(2008)
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.
Haematologica 93 (5), S. 688-696.
Lottaz, Claudio,
Kostka, Dennis und
Spang, Rainer
(2008)
26. Classification of Patients.
In:
Lengauer, Thomas, (ed.)
Bioinformatics-From Genomes to Therapies.
Wiley-VCH, Weinheim, S. 957-991.
ISBN 9783527619368 (online).
Volltext nicht vorhanden.
Hirsch, Burkhard,
Hummel, M.,
Bentink, Stefan,
Fouladi, F.,
Spang, Rainer,
Zollinger, R.,
Stein, H. und
Durkop, H.
(2008)
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells.
The American Journal of Pathology 172 (2), S. 510-520.
Volltext nicht vorhanden.
Montesinos-Rongen, M.,
Brunn, A.,
Bentink, Stefan,
Basso, K.,
Lim, W. K.,
Klapper, Wolfram,
Schaller, C.,
Reifenberger, G.,
Rubenstein, J.,
Wiestler, O. D.,
Spang, Rainer,
Dalla-Favera, R.,
Siebert, Reiner und
Deckert, M.
(2008)
Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell.
Leukemia 22 (2), S. 400-405.
Volltext nicht vorhanden.
Lottaz, Claudio,
Kostka, Dennis,
Markowetz, Florian und
Spang, Rainer
(2008)
15. Computational diagnostics with gene expression profiles.
In:
Bioinformatics.
Methods in Molecular Biology, 453 (15).
Humana Press, Totowa, NJ, S. 281-296.
ISBN 978-1-60327-428-9.
Volltext nicht vorhanden.
2007
Roesch, Alexander,
Becker, Bernd,
Bentink, Stefan,
Spang, Rainer,
Vogl, Annegret,
Hagen, Ilja,
Landthaler, Michael und
Vogt, Thomas
(2007)
Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Prevention 16 (11), S. 2486-2490.
Volltext nicht vorhanden.
Rhein, P.,
Scheid, S.,
Ratei, R.,
Hagemeier, C.,
Seeger, K.,
Kirschner-Schwabe, R.,
Moericke, A.,
Schrappe, M.,
Spang, Rainer,
Ludwig, W.-D. und
Karawajew, L.
(2007)
Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.
Leukemia 21 (5), S. 897-905.
Volltext nicht vorhanden.
Jaeger, Jochen,
Koczan, Dirk,
Thiesen, Hans-Juergen,
Ibrahim, Saleh M.,
Gross, Gerd,
Spang, Rainer und
Kunz, Manfred
(2007)
Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues.
Clinical cancer research 13 (3), S. 806-815.
Volltext nicht vorhanden.
2006
Kirschner-Schwabe, R.,
Lottaz, Claudio,
Todling, J.,
Rhein, P.,
Karawajew, L.,
Eckert, C.,
von Stackelberg, A.,
Ungethum, U.,
Kostka, Dennis,
Kulozik, A. E.,
Ludwig, W. D.,
Henze, G.,
Spang, Rainer,
Hagemeier, C. und
Seeger, K.
(2006)
Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia.
Clinical Cancer Research 12 (15), S. 4553-4561.
Volltext nicht vorhanden.
Hummel, M.,
Bentink, S.,
Berger, H.,
Klapper, W.,
Wessendorf, S.,
Barth, T. F.,
Bernd, H. W.,
Cogliatti, S. B.,
Dierlamm, J.,
Feller, A. C. und
Spang, Rainer
(2006)
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.
New England Journal of Medicine 354 (23), S. 2419-2430.
Volltext nicht vorhanden.
Yang, X.,
Bentink, S.,
Scheid, S. und
Spang, Rainer
(2006)
Similarities of ordered gene lists.
Journal of Bioinformatics and Computational BiologyJ Bioinform Comput Biol 4 (3), S. 693-708.
Volltext nicht vorhanden.
2005
2004
2003
Grzeskowiak, R.,
Witt, Henning,
Drungowski, M.,
Thermann, R.,
Hennig, S.,
Perrot, A.,
Osterziel, K.,
Klingbiel, D.,
Scheid, Stefanie und
Spang, Rainer
(2003)
Expression profiling of human idiopathic dilated cardiomyopathy.
Cardiovascular Research 59, S. 400-411.
Volltext nicht vorhanden.
2002
Spang, Rainer,
Zuzan, H.,
West, M.,
Nevins, J.,
Blanchette, C. und
Marks, J. R.
(2002)
Prediction and uncertainty in the analysis of gene expression profiles.
In Silico Biology 2 (3), S. 369-381.
Volltext nicht vorhanden.
2001
West, M.,
Blanchette, C.,
Dressman, H.,
Huang, E.,
Ishida, S.,
Spang, Rainer,
Zuzan, H.,
Olson, J. A.,
Marks, J. R. und
Nevins, J. R.
(2001)
Predicting the clinical status of human breast cancer by using gene expression profiles.
Proc. Natl. Acad. Sci. U.S.A. 98 (20), S. 11462-11467.
Volltext nicht vorhanden.
Ishida, S.,
Huang, E.,
Zuzan, H.,
Spang, Rainer,
Leone, G.,
West, M. und
Nevins, J. R.
(2001)
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis.
Mol. Cell. Biol. 21 (14), S. 4684-4699.
Volltext nicht vorhanden.
2000
1998
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