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Number of items: 159.

Wifling, David and Löffel, Karolin and Nordemann, Uwe and Strasser, Andrea and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Buschauer, Armin (2014) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology. (In Press)

Geyer, Roland and Kaske, Melanie and Baumeister, Paul and Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), pp. 77-88.

Geyer, Roland and Igel, Patrick and Kaske, Melanie and Elz, Sigurd and Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), pp. 72-81.

Dove, Stefan and Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), pp. 3-9.

Schreeb, Annemarie and Łażewska, Dorota and Dove, Stefan and Buschauer, Armin and Kieć-Kononiwcz, Katarzyna and Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, pp. 21-62. ISBN 9788376560564.

Keller, Max and Kaske, Melanie and Holzammer, Tobias and Bernhardt, Günther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), pp. 6303-6322.

Nordemann, Uwe and Wifling, David and Schnell, David and Bernhardt, Günther and Stark, Holger and Seifert, Roland and Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Brunskole Hummel, Irena and Kälble, Solveig and Burhenne, Heike and Reinartz, Michael T. and Schwede, Frank and Buschauer, Armin and Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Pluym, Nikola and Baumeister, Paul and Keller, Max and Bernhardt, Günther and Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), pp. 587-593.

Seifert, Roland and Strasser, Andrea and Schneider, Erich H. and Neumann, Detlef and Dove, Stefan and Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), pp. 33-58.

Strasser, Andrea and Wittmann, Hans-Joachim and Buschauer, Armin and Schneider, Erich H. and Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), pp. 13-32.

Bodensteiner, Julian and Baumeister, Paul and Geyer, Roland and Buschauer, Armin and Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), pp. 4040-55.

Memminger, Martin and Keller, Max and Lopuch, Miroslaw and Pop, Nathalie and Bernhardt, Günther and von Angerer, Erwin and Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Reher, Till M. and Neumann, Detlef and Buschauer, Armin and Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), pp. 192-203.

Birnkammer, Tobias and Spickenreither, Anja and Brunskole, Irena and Lopuch, Miroslaw and Kagermeier, Nicole and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), pp. 1147-1160.

Appl, Heidrun and Holzammer, Tobias and Dove, Stefan and Haen, Ekkehard and Strasser, Andrea and Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170.

Brunskole, Irena and Strasser, Andrea and Seifert, Roland and Buschauer, Armin (2011) Role of the second and third extracellular loops of the histamine H4 receptor in receptor activation. Naunyn-Schmiedeberg's Archives of Pharmacology 384 (3), pp. 301-317.

Braun, Stephan and Botzki, Alexander and Salmen, Sunnhild and Textor, Christian and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (2011) Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase. European Journal of Medicinal Chemistry 46 (9), pp. 4419-4429.

Hübner, Melanie and Dixit, A. and Mou, T.-C. and Lushington, Gerald H. and Pinto, Cibele S. and Gille, A. and Geduhn, Jens and König, Burkhard and Sprang, S. R. and Seifert, Roland (2011) Structural Basis for the High-Affinity Inhibition of Mammalian Membranous Adenylyl Cyclase by 2`,3`-O-(N-Methylanthraniloyl)-Inosine 5`-Triphosphate. Molecular Pharmacology 80 (1), pp. 87-96.

Pluym, Nikola and Brennauer, Albert and Keller, Max and Ziemek, Ralf and Pop, Nathalie and Bernhardt, Günther and Buschauer, Armin (2011) Application of the guanidine – acylguanidine bioisosteric approach to argininamide-type NPY Y2 receptor antagonists. ChemMedChem 6 (9), pp. 1727-1738.

Geyer, Roland and Buschauer, Armin (2011) Synthesis and histamine H3 and H4 receptor activity of conformationally restricted cyanoguanidines related to UR-PI376. Archiv der Pharmazie 344 (12), pp. 775-785.

Keller, Max and Bernhardt, Günther and Buschauer, Armin (2011) [3H]UR-MK136 - a highly potent and selective radioligand for neuropeptide Y Y1 receptors. ChemMedChem 6 (9), pp. 1566-1571.

Pop, Nathalie and Igel, Patrick and Brennauer, Albert and Cabrele, Chiara and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2011) Functional reconstitution of human neuropeptide Y (NPY) Y2 and Y4 receptors in Sf9 insect cells. Journal of Receptors and Signal Transduction 31 (4), pp. 271-285.

Keller, Max and Erdmann, Daniela and Teng, Shangjun and Pop, Nathalie and Pluym, Nikola and Bernhardt, Günther and Buschauer, Armin (2011) Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools. Bioorganic & Medicinal Chemistry 19 (9), pp. 2859-2878.

Schnell, David and Brunskole, Irena and Ladova, Katerina and Schneider, Erich H. and Igel, Patrick and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2011) Expression and functional properties of canine, rat and murine histamine H4-receptors in Sf9 insect cells. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (5), pp. 457-470.

Seifert, Roland and Schneider, Erich H. and Dove, Stefan and Brunskole, Irena and Neumann, Detlef and Strasser, Andrea and Buschauer, Armin (2011) Paradoxical stimulatory effects of the “standard” histamine H4-receptor antagonist JNJ7777120: The H4-receptor joins the club of 7TM receptors exhibiting functional selectivity. Molecular Pharmacology 79 (4), pp. 631-638.

Geduhn, Jens and Dove, Stefan and Shen, Yuequan and Tang, Wei-Jen and König, Burkhard and Seifert, Roland (2011) Bis-Halogen-Anthraniloyl-Substituted Nucleoside 5'-triphosphates as Potent and Selective Inhibitors of Bordetella pertussis CyaA. The Journal of pharmacology and experimental therapeutics 336 (1), pp. 104-115.

Schinner, Elisabeth and Salb, Katharina and Schlossmann, Jens (2011) Signaling via IRAG is essential for NO/cGMP-dependent inhibition of platelet activitation. Platelets.

Silva, Maria Elena and Heim, Ralf and Strasser, Andrea and Elz, Sigurd and Dove, Stefan (2011) Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor. Journal of computer-aided molecular design 25 (1), pp. 51-66.

Fischer, Carolin and König, Burkhard (2011) Palladium and copper mediated N-aryl bond formation reactions for the synthesis of biological active compounds. Beilstein Journal of Organic Chemistry (7), pp. 59-74.

Ehlers, I. and Maity, P. and Aube, J. and König, Burkhard (2011) Modular Synthesis of Triazole-Containing Triaryl α-Helix Mimetics. European Journal of Organic Chemistry, pp. 2474-2490.

Ochoa Puentes, Cristian and Höcherl, Peter and Kühnle, Matthias and Bauer, Stefanie and Kürger, Kira and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2011) Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). Bioorganic & Medicinal Chemistry Letters 21 (12), pp. 3654-3657.

Weiss, Stefan and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2011) Synthesis and characterization of DMAP-Modified NPY Y1 receptor antagonists as acyl-transfer catalysts. Collection of Czechoslovak chemical communications 76 (6), 763 -780.

Igel, Patrick and Dove, Stefan and Buschauer, Armin (2010) Histamine H4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199.

Desch, Matthias and Schinner, Elisabeth and Kees, Frieder K. and Hofmann, F. and Seifert, Roland and Schlossmann, Jens (2010) Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I. FEBS Letters 584 (18), pp. 3979-3984.

Hild, Wolfgang and Pollinger, Klaus and Caporale, Andrea and Cabrele, Chiara and Keller, Max and Pluym, Nicola and Buschauer, Armin and Rachel, Reinhard and Tessmar, Joerg and Breunig, Miriam and Goepferich, Achim (2010) G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake. Proceedings of the National Academy of Sciences USA: PNAS 107 (23), pp. 10667-10672.

Desch, Matthias and Sigl, K. and Hieke, Bernhard and Salb, Katharina and Kees, F. and Bernhard, D. (2010) IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovascular Research 86 (3), pp. 496-505.

Ghorai, Prasanta and Kraus, Anja and Birnkammer, Tobias and Geyer, Roland and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2010) Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity. Bioorganic & Medicinal Chemistry Letters 20 (10), pp. 3173-3176.

Pollinger, Klaus and Breunig, Miriam and Tessmar, Joerg and Göpferich, Achim (2010) "Receptor mediated targeting of micelles - the folate receptor as proof of principle". In: "5th Summer School Medicinal Chemistry" , 13. - 15. September 2010, Regensburg.

Kleinmaier, R. and Gschwind, R. M. (2010) Chemical Shift Assignment and Conformational Analysis of Monoalkylated Acylguanidines. Magn. Reson. Chem. 48 (9), pp. 687-684.

Kleinmaier, R. and Igel, P. and Keller, M. and Buschauer, Armin and Gschwind, R. M. (2010) Conformations, Conformational Preferences, and Conformational Exchange of N'-Substituted N-Acylguanidines: Intermolecular Interactions Hold the Key. J. Am. Chem. Soc. 132 (32), pp. 11223-11233.

Späth, A. and König, Burkhard (2010) Ditopic crown ether – guanidinium ion receptors for the molecular recognition of amino acids and small peptides. Tetrahedron (66), pp. 1859-1873.

Geiger, Sarah and Nickl, Kathrin and Schneider, Erich H. and Seifert, Roland and Heilmann, Jörg (2010) Establishment of recombinant cannabinoid receptor assays and characterization of several natural and synthetic ligands. Naunyn-Schmiedebergs Archiv für Pharmakologie 382 (2), pp. 177-191.

Schneider, Erich H. and Schnell, David and Strasser, Andrea and Dove, Stefan and Seifert, Roland (2010) Impact of the DRY Motif and the Missing "Ionic Lock" on Constitutive Activity and G-Protein Coupling of the Human Histamine H-4 Receptor. Journal of Pharmacology and Experimental Therapeutics 333 (2), pp. 382-392.

König, Burkhard and Späth, A. and Koch, C. (2010) Luminescent Hybrids Combining a Metal Complex and a Crown Ether – Receptors for Peptidic Ammonium Phosphates. European Journal of Inorganic Chemistry (19), pp. 2926-2935.

Weiss, Stefan and Keller, Max and Bernhardt, G. and Buschauer, Armin and König, Burkhard (2010) N(G)-Acyl-argininamides as NPY Y (1) receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity. Bioorganic & Medicinal Chemistry (18), pp. 6292-6304.

Rosnizeck, I C. and Graf, T. and Spoerner, M. and Tränkle, J. and Filchtinski, D. and Herrmann, C. and Gremer, L. and Vetter, I. and Wittinghofer, A. and König, Burkhard and Kalbitzer, H. R. (2010) Stabilizing a Weak Binding State for Effectors in the Human Ras Protein by Cyclen Complexes. Angewandte Chemie International Edition (49), pp. 3830-3833.

Igel, Patrick and Geyer, Roland and Straßer, Andrea and Dove, Stefan and Seifert, Roland and Buschauer, Armin (2009) Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H(4) receptor agonists. Journal of Medicinal Chemistry 52 (20), pp. 6297-6313.

Keller, Max and Teng, Shangjun and Bernhardt, Günther and Buschauer, Armin (2009) Bivalent argininamide-type neuropeptide Y Y1 antagonists do not support the hypothesis of receptor dimerisation. ChemMedChem 4 (10), pp. 1733-1745.

Igel, Patrick and Schneider, Erich and Schnell, David and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2009) N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. Journal of Medicinal Chemistry 52 (8), pp. 2623-2627.

Kraus, Anja and Ghorai, Prasanta and Birnkammer, Tobias and Schnell, David and Elz, Sigurd and Seifert, Roland and Dove, Stefan and Bernhardt, Günther and Buschauer, Armin (2009) N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists. ChemMedChem 4 (2), pp. 232-240.

Igel, Patrick and Schnell, David and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2009) Tritium-labeled N1-[3-(1H-imidazol-4-yl)propyl]-N2-propionylguanidine ([3H]UR-PI294), a high affinity histamine H3 and H4 receptor radioligand. ChemMedChem 4 (2), pp. 225-231.

Kühnle, Matthias and Egger, Michael and Müller, Christine and Mahringer, Anne and Bernhardt, Günther and Fricker, Gert and König, Burkhard and Buschauer, Armin (2009) Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. Journal of Medicinal Chemistry 52 (4), pp. 1190-1197.

Hild, Wolfgang and Pollinger, Klaus and Caporale, Andrea and Cabrele, Chiara and Breunig, Miriam and Tessmar, Joerg and Göpferich, Achim (2009) "Nanoparticle Delivery into Target Cells by G-Protein Coupled Receptors". In: 36th Annual Meeting of Controlled release Society, 18. - 22. Juli 2009, Kopenhagen, Dänemark.

Vomasta, Daniel and Innocenti, A. and König, Burkhard and Supuran, T. (2009) Carbonic anhydrase inhibitors: Two-prong versus mono-prong inhibitors of isoformsI, II, IX and XII exemplified by photochromics cis-1,2-a-dithienylethene derivates. Bioorganic & Medicinal Chemistry Letters 19, pp. 1283-1286.

Riechers, Alexander and Schmidt, Florian and Stadlbauer, Stefan and König, Burkhard (2009) Detection of protein phosphorylation on SDS-PAGE using probes with a phosphate-sensitive emmision response. Bioconjugate Chemistry 20, pp. 804-807.

Dirscherl, G. and Schwab, M. and Seufert, W. and König, Burkhard (2009) Enhancing the Separation of Phosphorylated Proteins in Gel Electrophoresis with Dinuclear Bispyridylmethylamine-Tyrosine-Acrylamide Complexes. Inorg. Chim Acta 362, 537 - 542.

Seifert, Roland and Dove, Stefan (2009) Functional Selectivity of GPCR Ligand Stereoisomers: New Pharmacological Opportunities. Mol. Pharmacol. 75 (1), pp. 13-18.

Grauer, Andreas and Späth, Andreas and Ma, Dawei and König, Burkhard (2009) Metal-catalyzed derivatization of C alpha-tetrasubstituted amino acids and their use in the synthesis of cyclic peptides. Chemistry - An Asian Journal 4 (7), pp. 1134-1140.

Späth, A. and König, Burkhard (2009) Modular Synthesis of Di- and Tripeptides of Luminescent Crown Ether Aminocarboxylic Acids. Tetrahedron 65, 690 - 695.

Taha, H. M. and Schmidt, J. and Göttle, M. and Suryanarayana, S. and Shen, Y. and Tang, W.-J. and Gille, A. and Geduhn, Jens and König, Burkhard and Dove, Stefan and Seifert, Roland (2009) Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides. Mol. Pharmacol. 75 (3), pp. 693-703.

Grauer, Andreas and König, Burkhard (2009) Peptidomimetics – A versatile route to biologically active compounds. European Journal of Organic Chemistry, pp. 5099-5111.

Schmid, M. and Fleischmann, M. and D´Elia, V. and Reiser, O. and Gronwald, W. and Gschwind, R. M. (2009) RDCs in Short Peptidic Foldamers: Combined Analyses of Backbone and Side Chain Conformations and Evaluation of Structure Coordinates of Rigid Unnatural Amino Acids. ChemBioChem 10 (3), pp. 440-444.

Kleinmaier, R. and Gschwind, R. M. (2009) Selective [15N.eta.2] labelling of an NG-propionylated arginine derivative. Journal of Labelled Compounds and Radiopharmaceuticals 52 (2), pp. 29-32.

Grauer, Andreas and Cabrele, C. and Zabel, M. and König, Burkhard (2009) Stable right- and left-handed peptide helices containing Cα-tetrasubstituted α amino acids. The Journal of Organic Chemistry 74 (10), pp. 3718-3726.

Egger, Michael and Maity, Prantik and Hübner, Melanie and Seifert, Roland and König, Burkhard (2009) Synthesis and pharmacological properties of new tetracyclic forskolin analogues. European Journal of Organic Chemistry 2009 (21), pp. 3613-3618.

Grauer, Andreas and König, Burkhard (2009) Synthesis of new Ca-tetrasubstituted a-amino acids. Beilstein Journal of Organic Chemistry 5 (5).

Keller, Max and Pop, Nathalie and Hutzler, Christoph and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2008) Guanidine - acylguanidine bioisosteric approach in the design of radioligands: Synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist. Journal of Medicinal Chemistry 51 (24), pp. 8168-8172.

Ghorai, Prasanta and Kraus, Anja and Keller, Max and Götte, Carsten and Igel, Patrick and Schneider, Erich and Schnell, David and Bernhardt, Günther and Dove, Stefan and Zabel, Manfred and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2008) Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists. Journal of Medicinal Chemistry 51 (22), pp. 7193-7204.

Weiss, Stefan and Keller, Max and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2008) Modular synthesis of non-peptidic bivalent NPY Y(1) receptor antagonists. Bioorganic & Medicinal Chemistry 16 (22), pp. 9858-9866.

Subat, M. and Woinaroschy, K. and Gerstl, C. and Sarkar, B. and Kaim, W. and König, B. (2008) 1,4,7,10 - Tetraazacyclododecane Metal Complexes as Potent Promoters of Phosphodiester Hydrolysis under Physiologica. Inorg. Chem. 47, 4661 - 4668.

Engel, E. and Ulrich, H. and Vasold, R. and König, B. and Landthaler, M. and Süttinger, R. and Bäumler, W. (2008) Azo Pigment and a Basal Cell Carcinoma at the Thumb. Dermatology 216, pp. 76-80.

Nickl, Kathrin and Gardner, Eric E. and Geiger, Sarah and Heilmann, Jörg and Seifert, Roland (2008) Differential coupling of the human cannabinoid receptors hCB1R and hCB2R to the G-protein Galpha i2beta 1gamma 2. Neuroscience letters 447 (1), pp. 68-72.

Vasold, R. and Engel, E. and König, B. and Landthaler, M. and Baeumler, W. (2008) Health risks of tattoo colors. Anal. Bioanal. Chem. 391, 9 - 13.

Hofinger, Edith S. A. and Hoechstetter, Julia and Oettl, Martin and Bernhardt, Günther and Buschauer, Armin (2008) Isoenzyme-specific differences in the degradation of hyaluronic acid by mammalian-type hyaluronidases. Glycoconjugate Journal 25 (2), pp. 101-109.

Hild, Wolfgang and Pollinger, Klaus and Caporale, Andrea and Cabrele, Chiara and Breunig, Miriam and Tessmar, Joerg and Goepferich, Achim (2008) Peptide-mediated nanoparticle delivery by G-protein coupled receptors (GPCRs). In: Summer school "Medicinal Chemistry: Molecular Recognition – Ligand Receptor Interactions”, 29. September - 1. Oktober 2008, Regensburg.

Hild, W. A. and Breunig, Miriam and Göpferich, Achim (2008) Quantum dots - Nano-sized probes for the exploration of cellular and intracellular targeting. European Journal of Pharmaceutics and Biopharmaceutics 68 (2), pp. 153-168.

Kiewitz, S.D. and Kruppa, M. and Riechers, A. and König, B. and Cabrele, C. (2008) Recognition of the Helix-Loop-Helix Domain of the Id Proteins by an Artificial Luminescent Metal Complex Receptor. J. Mol. Recognit 21, 79 - 88.

Vomasta, D. and Högner, C. and Branda, N. R. and König, B. (2008) Regulation of Human Carbonic Anhydrase I (hCAI) Activity by Using a Photochromic Inhibitor. Angew. Chem. 120, pp. 7756-7759.

Egger, M. and Pellett, P. and Nickl, K. and Geiger, S. and Graetz, S. and Seifert, R. and Heilmann, J. and König, B. (2008) Synthesis and Cannabinoid Receptor Activity of Ketoalkenes from Echinacea pallida and Non-natural Analogues. Chem. Eur. J. 14, 10978 - 10984.

Maity, P. and König, B. (2008) Synthesis and Structure of 1,4-Dipiperazino Benzenes - Chiral Terphenyl-type Peptide. Org. Lett. 10, 1473 - 1476.

Grauer, A. and Riechers, A. and Ritter, S. and König, B. (2008) Synthetic Receptors for the Differentiation of Phosphorylated Peptides with Nanomolar Affinities. Chem. Eur. J. 14, 8922 - 8927.

Federwisch, G. and Kleinmaier, R. and Drettwan, D. and Gschwind, R. M. (2008) The H-Bonding Network of Acylguanidine Complexes: Combined Intermolecular 2hJH,P and 3hJN,P Scalar Couplings Provide an Insight into the Geometric Arrangement. Journal of the American Chemical Society 130 (50), pp. 16846-16847.

Dirscherl, G. and König, B. (2008) The Use of Solid-Phase Synthesis Techniques for the Preparation of Peptide - Metal Complex Conjugates. Eur. J. Org. Chem., 597 - 634.

Hild, W. and Zenger, Katharina and Caporale, A. and Cabrele, C. and Breunig, Miriam and Teßmar, Jörg and Göpferich, Achim (2008) Towards peptide-modified nanocrystals for drug targeting applications. In: Controlled Release Society, Local Chapter, Braunschweig.

Stadlbauer, S. and Riechers, A. and Späth, A. and König, B. (2008) Utilizing Reversible Copper(II) Peptide Coordination in a Sequence Selective Luminescent Receptor. Chem. Eur. J. 14, 2536 - 2541.

Göttle, Martin and Dove, Stefan and Steindel, Phillip and Shen, Yuequan and Tang, Wei-Jen and Geduhn, Jens and König, Burkhard and Seifert, Roland (2007) Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides. Molecular Pharmacology 72 (3), pp. 526-535.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Constitutive Activity and Ligand Selectivity of Human,
Guinea Pig, Rat, and Canine Histamine H₂ Receptors.
Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 983-995.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Mutations of Cys-17 and Ala-271 in the Human Histamine H₂
Receptor Determine the Species Selectivity of Guanidine-Type Agonists and Increase Constitutive Activity.
Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 975-982.

Hild, W. and Breunig, Miriam and Teßmar, Jörg and Göpferich, Achim (2007) Custom designed Quantum Dots for cellular uptake. In: Partec 2007, Nuernberg.

Brennauer, Albert and Keller, Max and Freund, Matthias and Bernhardt, Günther and Buschauer, Armin (2007) Decomposition of 1-(w-aminoalkanoyl)guanidines under alkaline conditions. Tetrahedron Letters 48 (39), pp. 6996-6999.

Ziemek, Ralf and Schneider, Erich and Kraus, Anja and Cabrele, Chiara and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2007) Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence. Journal of Receptors and Signal Transduction 27 (4), pp. 217-233.

Xie, Sheng-Xue and Schalkhausser, Fabian and Ye, Qi-Zhuang and Seifert, Roland and Buschauer, Armin (2007) Effects of Impromidine- and Arpromidine-Derived Guanidines on Recombinant Human and Guinea Pig Histamine H₁ and H₂ Receptors. Archiv der Pharmazie 340 (1), pp. 9-16.

Maity, P. and König, Burkhard (2007) Enantio- and Diastereoselective Syntheses of Cyclic Cα-Tetrasubstituted α-Amino Acids and Their Use to Induce Stable Conformations in Short Peptides (Review). Pept. Sci. 90, 8 - 27.

Zimmermann, Jochen and Angerer, Erwin von (2007) Estrogenic and antiestrogenic activities of 2,4-diphenylfuran-based ligands of estrogen receptors α and β. The Journal of Steroid Biochemistry and Molecular Biology 104 (3-5), pp. 259-268.

Hofinger, Edith S. A. and Bernhardt, Günther and Buschauer, Armin (2007) Kinetics of Hyal1 and PH-20 hyaluronidases: comparison of minimal substrates and analysis of the transglycosylation reaction. Glycobiology 17 (9), pp. 963-971.

Engel, E. and Spannberger, A. and Vasold, R. and König, B. and Landthaler, M. and Bäumler, W. (2007) Photochemical cleavage of a tattoo pigment by UVB radiation or natural sunlight. JDDG 5 (7), 583–589.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), pp. 253-264.

Hofinger, Edith S. A. and Spickenreither, Martin and Oschmann, Jan and Bernhardt, Günther and Rudolph, Rainer and Buschauer, Armin (2007) Recombinant human hyaluronidase Hyal-1: insect cells versus E. coli as expression system and identification of low molecular weight inhibitors. Glycobiology 17 (4), pp. 444-453.

Dirscherl, G. and Knape, R. and Hanson, P. and König, B. (2007) Solid Phase Synthesis of Metal-Complex containing Peptides. Tetrahedron 63, 4918 – 4928.

Schneider, Erich and Keller, Max and Brennauer, Albert and Hoefelschweiger, Bianca K. and Gross, Dietmar and Wolfbeis, Otto S. and Bernhardt, Günther and Buschauer, Armin (2007) Synthesis and Characterization of the First Fluorescent Nonpeptide NPY Y1 Receptor Antagonist. ChemBioChem 8 (16), pp. 1981-1988.

Egger, Michael and Li, Xuqin and Müller, Christine and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2007) Tariquidar analogues: synthesis by Cu(I)-catalysed N/O–aryl coupling and inhibitory activity against the ABCB1 transporter. European Journal of Organic Chemistry 2007 (16), pp. 2643-2649.

Maity, P. and Zabel, M. and König, B. (2007) Tetrahydrofuran Cα-Tetrasubstituted Amino Acids: Two Consecutive β Turns in a Crystalline Linear Tripeptide. J. Org. Chem. 72, 8046 – 8053.

Hild, W. and Lang, R. and Winter, G. and Göpferich, Achim (2007) Towards the characterization of quantum dots by asymmetrical flow field-flow fractionation. In: Jahrestagung der DPhG, Erlangen.

Xie, Sheng-Xue and Kraus, Anja and Ghorai, Prasanta and Ye, Qi-Zhuang and Elz, Sigurd and Buschauer, Armin and Seifert, Roland (2006) N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors.
Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268.

Wabnitz, Tobias C. and Rizzo, Simona and Götte, Carsten and Buschauer, Armin and Benincori, Tiziana and Reiser, Oliver (2006) Enantioselective hydrogenation of diaryl-substituted a,b-unsaturated nitriles. Tetrahedron Letters 47 (22), pp. 3733-3736.

Kruppa, Michael and Frank, Daniel and Leffler-Schuster, Helga and König, Burkhard (2006) Screening of Metal Complex – Amino Acid Side Chain Interactions by Potentiometric Titration. Inorganica Chimica Acta 359 (4), pp. 1159-1168.

Xie, Sheng-Xue and Ghorai, Prasanta and Ye, Qi-Zhuang and Buschauer, Armin and Seifert, Roland (2006) Probing Ligand-Specific Histamine H1- and H2-Receptor
Conformations with NG-Acylated Imidazolylpropylguanidines.
The Journal of Pharmacology and Experimental Therapeutics 317 (1), pp. 139-146.

Miltschitzky, Stefan and Michlova, Veronika and Stadlbauer, Stefan and König, Burkhard (2006) Synthesis of substituted pyrimidine hydrazine acids (PHA) and their use in peptide recognition. Heterocycles 67 (1), pp. 135-160.

Bonauer, Christoph and Walenzyk, Thomas and König, Burkhard (2006) α,β-Dehydroamino Acids. Synthesis (1), pp. 1-20.

Schneider, Erich and Mayer, Matthias and Ziemek, Ralf and Li, Liantao and Hutzler, Christoph and Bernhardt, Günther and Buschauer, Armin (2006) A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G-Protein-coupled Receptor Subtypes. ChemBioChem 7 (9), pp. 1400-1409.

Rigden, Daniel J. and Botzki, Alexander and Nukui, Masatoshi and Mewbourne, R. Brandon and Lamani, Ejvis and Braun, Stephan and von Angerer, Erwin and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin and Jedrzejas, Mark J. (2006) Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology 16 (8), pp. 757-765.

Engel, E. and Santarelli, F. and Vasold, R. and Ulrich, H. and Maisch, T. and König, B. and Landthaler, M. and Gopee, N. V. and Howard, P. C. and Bäumler, W. (2006) Establishment of an Extraction Method for the Recovery of Tattoo Pigments from Human Skin Using HPLC Diode Array Detector Technology. Anal. Chem. 78, 6440 - 6447.

Ziemek, Ralf and Brennauer, Albert and Schneider, Erich and Cabrele, Chiara and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2006) Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y(2) receptor ligands. European Journal of Pharmacology 551 (1-3), pp. 10-8.

Li, X. and Miltschitzky, Stefan and König, B. (2006) Luminescent Pyrimidine Hydrazide Oligomers with Peptide Affinity. Bioorganic & Medicinal Chemistry 14, 6075 -6084.

Knerr, Robert and Weiser, Barbara and Drotleff, S. and Steinem, C. and Göpferich, Achim (2006) Measuring cell adhesion on RGD-modified, self-assembled PEG monolayers using the quartz crystal microbalance technique. Macromolecular Bioscience 6 (10), pp. 827-838.

Spickenreither, Martin and Braun, Stephan and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (2006) Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases. Bioorganic & Medicinal Chemistry Letters 16 (20), pp. 5313-5316.

Hild, W. and Teßmar, Jörg and Göpferich, Achim (2006) Quantum dot colloids for cell-uptake studies. In: 3rd Summer School "Medicinal Chemistry", Regensburg.

Knerr, Robert and Drotleff, S. and Steinem, C. and Göpferich, Achim (2006) Self-assembling PEG Derivatives for Protein-repellant Biomimetic Model Surfaces on Gold. Biomaterialien 7 (1), pp. 12-20.

Li, X. and Miltschitzky, S. and Grauer, A. and Michlová, V. and König, B. (2006) Synthesis and Peptide-binding Properties of a Luminescent Pyrimidine Zinc(II) Complex. Tetrahedron 62, 12191 - 12196.

Xie, Sheng-Xue and Petrache, Georgiana and Schneider, Erich and Ye, Qi-Zhuang and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2006) Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine. Bioorganic & Medicinal Chemistry Letters 16 (15), pp. 3886-3890.

Maity, P. and König, B. (2006) Synthesis of 3-Oxo-2,3-dihydro-pyrrole Amino Acids as Chiral Dipeptidomimics. Synthesis (16), pp. 2719-2724.

Suhs, T. and König, B. (2006) Synthesis of Functionalized Guanidino Amino Acids. Chem. Eur. J. 12, 8150 – 8157.

Suhs, Thomas and König, Burkhard (2006) Synthesis of Guanidines in Solution. Mini-Reviews in Organic Chemistry 3, pp. 315-331.

Knerr, Robert and Weiser, Barbara and Drotleff, Sigrid and Steinem, Claudia (2005) "Protein adsorption and cell adhesion on RGD modified PEG monolayers". In: "European Symposium on polymeric Biomaterials", 2005, Madrid, Spanien.

Zimmermann, Jochen and Liebl, Renate and Angerer, Erwin von (2005) 2,5-Diphenylfuran-based pure antiestrogens with selectivity for the estrogen receptor alpha. The Journal of Steroid Biochemistry and Molecular Biology 94 (1-3), pp. 57-66.

Kruppa, M. and Mandl, C. and Miltschitzky, S. and König, B. (2005) A Luminescent Receptor with Affinity for N-terminal Histidine in Peptides in Aqueous Solution. J. Am. Chem. Soc. 127, 3362 - 3365.

Kalbitzer, H. R. and Spoerner, M. and Graf, T. and König, B. (2005) A Novel Mechanism for the Modulation of the Ras-Effector Interaction by small molecules. Biochem. Biophys. Res. Commun. 334, 709 – 713.

Ritter, S. and Eiblmeier, M. and Michlova, V. and König, B. (2005) Chiral NADH Model Systems functionalized with Zn(II)-cyclen as Flavin Binding Site. Tetrahedron 61, 5241 - 5251.

Kruppa, M. and Bonauer, C. and Michlová, V. and König, B. (2005) Enhanced Peptide β-Sheet Affinity by Metal to Ligand Coordination. J. Org. Chem. 70, 5305 - 5308.

Mandl, C. P. and König, B. (2005) Luminescent Crown Ether Amino Acids - Selective Binding to N-terminal Lysine in Peptides. J. Org. Chem. 70, 670 – 674.

Knerr, Robert and Weiser, Barbara and Drotleff, S. and Steinem, C. and Göpferich, Achim (2005) Protein adsorption and cell adhesion on RGD modified PEG monolayers. In: Life Science Interface Summer School, University of Nottingham, Nottingham, UK.

Gschwind, R. M. (2005) Residual Dipolar Couplings - AValuable NMR Parameter for Small Organic Molecules. Angewandte Chemie International Edition 44 (30), pp. 4666-4668.

König, S. Miltschitzky and B. (2005) Small Peptides with a β-Hairpin Structure. Org. Prep. Proced. Int. 37, 307 – 336.

Botzki, Alexander and Salmen, Sunnhild and Bernhardt, Günther and Buschauer, Armin and Dove, Stefan (2005) Structure-Based Design Of Bacterial Hyaluronan Lyase Inhibitors,. QSAR & Combinatorial Science 24 (4), pp. 458-469.

Salmen, Sunnhild and Hoechstetter, Julia and Käsbauer, Christian and Paper, Dieter H. and Bernhardt, Günther and Buschauer, Armin (2005) Sulphated Oligosaccharides as Inhibitors of Hyaluronidases from Bovine Testis, Bee Venom and Streptococcus agalactiae. Planta Med. 71, pp. 727-732.

Bonauer, C. and König, B. (2005) Synthesis and Structure of Chiral Methoxypyrrole Amino Acids (MOPAS). Synthesis, 2367 - 2372.

Subat, M. and Borovik, A. S. and König, B. (2004) A Synthetic Creatinine Receptor: Imprinting of a Lewis-Acidic Zinc(II)cyclen Binding Site to Shape its Molecular Recognition Selectivity. J. Am. Chem. Soc. 126, 3185 - 3190.

Knerr, Robert and Steinem, C. and Roberts, C. J. and Göpferich, Achim (2004) A model to investigate cell surface interactions: PEGylated alkanethiolates on gold - protein resistance and visualization. In: Transactions, 31st annual meeting and exposition of the Controlled Release Society, Honolulu, HI.

Wiest, O. and Harrison, C.B. and Saettel, N. J. and Cibulka, R. and Sax, M. and König, B. (2004) Design, Synthesis, and Evaluation of a Biomimetic Artificial Photolyase Model. J. Org. Chem. 69, 8183 – 8185.

Klein, M. and Walenzyk, T. and König, B. (2004) Electronic Effects on the Bergman Cyclisation of Enediynes. A Review. Collect. Czech. Chem. Commun. 69, 945 – 965.

Botzki, Alexander and Rigden, Daniel J. and Braun, Stephan and Nukui, Masatoshi and Salmen, Sunnhild and Hoechstetter, Julia and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin and Jedrzejas, Mark J. (2004) L-ascorbic acid-6-hexadecanoate, a potent hyaluronidase inhibitor: X-ray structure and molecular modeling of enzyme-inhibitor complexes. The Journal of Biological Chemistry 279 (44), pp. 45990-45997.

Gschwind, R. M. and Armbrüster, M. and Zubrzycki, I. Z. (2004) NMR detection of intermolecular NH×××OP hydrogen bonds between guanidinium protons and bisposphonate moieties in an artificial arginine receptor. Journal of the American Chemical Society 126 (33), pp. 10228-10229.

Rzepecki, P. and Gallmeier, H. and Geib, N. and König, B. and Schrader, T. (2004) New heterocyclic β-sheet ligands with peptidic recognition elements. J. Org. Chem. 69, 5168 – 5178.

Černovská, K. and Kemter, M. and Gallmeier, H.-C. and Rzepecki, P. and Schrader, T. and König, B. (2004) PEG-supported Synthesis of Pyrazole Oligoamides with Peptide β-Sheet Affinity. Org. Biomol. Chem. 2, 1603 - 1611.

Knerr, Robert and Steinem, C. and Roberts, C. J. and Göpferich, Achim (2004) Self - assembled monolayers of PEGylated alkanethiolates on gold - A model to investigate cell - surface interactions. In: 2nd Summer School Medicinal Chemistry, University of Regensburg, Regensburg, Germany.

Knerr, Robert and Steinem, C. and Roberts, C. J. and Göpferich, Achim (2004) Self - assembled monolayers of PEGylated alkanethiolates on gold - A model to investigate cell - surface interactions. In: DPHG, ÖPHG, CPS Joint Meeting 2004, Regensburg, Germany.

Dove, Stefan and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2004) Structure-Activity Relationships of Histamine H_2 Receptor Ligands,. Mini-Rev. Med. Chem. 4 (9), pp. 941-954.

Brennauer, Albert and Dove, Stefan and Buschauer, Armin (2004) 18. Structure-Activity Relationships of Nonpeptide Neuropeptide Y Receptor Antagonists. In: Michel, M. C., (ed.) Neuropeptide Y and Related Peptides. Handbook of Experimental Pharmacology, 162 (18). Springer, Heidelberg, pp. 505-546. ISBN 978-3-540-40581-8.

Klein, M. and König, B. (2004) Synthesis and Thermal Cyclization of an Enediyne-Sulfonamide. Tetrahedron 60, 1087 - 1092.

Bonauer, C. and Zabel, M. and König, B. (2004) Synthesis and peptide binding properties of methoxypyrrole amino acids (MOPAS). Org. Lett. 6, 1349 - 1352.

Vasold, R. and Naarmann, N. and Ulrich, H. and Fischer, D. and König, B. and Landthaler, M. and Bäumler, W. (2004) Tattoo Pigments are Cleaved by Laser Light – The Chemical Analysis In Vitro Provide Evidence for Hazardous Compounds. Photochem. Photobiol. 80, 185 – 190.

Li, Liantao and Mayer, Matthias and Schneider, Erich and Schreiber, Elvira and Bernhardt, Günther and Peng, Shiqi and Buschauer, Armin (2003) Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A. Arch Pharm (Weinheim) 336 (12), pp. 585-590.

Gallmeier, H.-C. and König, B. (2003) Heteroaromatic Oligoamides with dDNA Affinity (review). Eur. J. Org. Chem., 3473 - 3483.

Klein, Michael and Zabel, Manfred and Bernhardt, Günther and König, Burkhard (2003) Tetrahydroxy 10-membered cyclic enediynes. The Journal of organic chemistry 68 (24), pp. 9379-9383.

Knerr, Robert and Steinem, Claudia and Göpferich, Achim (2002) Intergin-mediated interactions between cells amd biomimetic materials. In: "Summer School Medicinal Chemistry", 15. - 18. September 2002, Regensburg.

Pitsch, W. and Klein, M. and Zabel, M. and König, B. (2002) Synthesis and Structure of a Stabilized 10-Membered Cyclic Enediyne. J. Org. Chem. 67, 6805 - 6807.

König, B. and Pitsch, W. and Klein, M. and Vasold, R. and Prall, M. and Schreiner, P. R. (2001) Carbonyl- and Carboxyl-substituted Enediynes: Synthesis, Computations, and Thermal Reactivity. J. Org. Chem. 66, pp. 1742-1746.

König, B. (2000) Changing the Reactivity of Enediynes by Metal Ion Coordination (review). Eur. J. Org. Chem., pp. 381-385.

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