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Impact of Drosophila Models in the Study and Treatment of Friedreich’s Ataxia

Monnier, Véronique, Llorens, Jose Vicente and Navarro, Juan Antonio (2018) Impact of Drosophila Models in the Study and Treatment of Friedreich’s Ataxia. International Journal of Molecular Sciences.

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Date of publication of this fulltext: 29 Aug 2018 13:18

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Drosophila melanogaster has been for over a century the model of choice of several neurobiologists to decipher the formation and development of the nervous system as well as to mirror the pathophysiological conditions of many human neurodegenerative diseases. The rare disease Friedreich’s ataxia (FRDA) is not an exception. Since the isolation of the responsible gene more than two decades ago, the ...


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Item type:Article
Date:7 July 2018
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Entwicklungsbiologie (Prof. Dr. Stephan Schneuwly)
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Keywords:Drosophila melanogaster; Friedreich’s ataxia; frataxin; iron; oxidative stress; metal homeostasis; lipid metabolism; endoplasmic reticulum; genetic screens; drug screens
Dewey Decimal Classification:500 Science > 590 Zoological sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:37614
Owner only: item control page


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