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Isolation of Subtype 3c, 3e and 3f-Like Hepatitis E Virus Strains Stably Replicating to High Viral Loads in an Optimized Cell Culture System

Schemmerer, Mathias , Johne, Reimar, Erl, Monika, Jilg, Wolfgang and Wenzel, Jürgen J. (2019) Isolation of Subtype 3c, 3e and 3f-Like Hepatitis E Virus Strains Stably Replicating to High Viral Loads in an Optimized Cell Culture System. Viruses 11 (6), p. 483.

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Date of publication of this fulltext: 04 Jul 2019 04:57

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Other URL: http://doi.org/10.3390/v11060483


Abstract

The hepatitis E virus (HEV) is transmitted via the faecal–oral route in developing countries (genotypes 1 and 2) or through contaminated food and blood products worldwide (genotypes 3 and 4). In Europe, HEV subtypes 3c, 3e and 3f are predominant. HEV is the leading cause of acute hepatitis globally and immunocompromised patients are particularly at risk. Because of a lack of cell culture systems ...

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Item type:Article
Date:28 May 2019
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/v11060483DOI
Keywords:hepatitis E virus; cell culture; whole genome; wild-type HEV isolation; high viral loads
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40452
Owner only: item control page

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