Entries of Abken, Hinrich on the publication server

Harrer, Dennis Christoph , Haferkamp, Sebastian , Herr, Wolfgang, Mycielska, Maria E. , Dörrie, Jan, Schaft, Niels, Abken, Hinrich and Drexler, Konstantin (2026) Boosting the Activity of Melanoma-Targeting CAR-T Cells in the Presence of Citrate by the Application of Gluconate. Pharmaceutics 18 (5), p. 551.

Harrer, Dennis Christoph , Schlierkamp-Voosen, Tim, Barden, Markus, Pan, Hong, Xydia, Maria, Herr, Wolfgang, Dörrie, Jan, Schaft, Niels and Abken, Hinrich (2025) Chimeric Antigen Receptor (CAR) T Cells Releasing Soluble SLAMF6 Isoform 2 Gain Superior Anti-Cancer Cell Functionality in an Auto-Stimulatory Fashion. Cells 14 (12), p. 901.

Harrer, Dennis Christoph , Eder, Matthias, Barden, Markus, Pan, Hong, Herr, Wolfgang and Abken, Hinrich (2024) Ectopic PU.1 Expression Provides Chimeric Antigen Receptor (CAR) T Cells with Innate Cell Capacities Including IFN-β Release. Cancers 16 (15), p. 2737.

Harrer, Dennis Christoph , Li, Sin-Syue, Kaljanac, Marcell, Bezler, Valerie, Barden, Markus, Pan, Hong, Herr, Wolfgang and Abken, Hinrich (2024) Magnetic CAR T cell purification using an anti-G4S linker antibody. Journal of Immunological Methods 528, p. 113667.

Delacher, Michael , Schmidleithner, Lisa , Simon, Malte , Stüve, Philipp , Sanderink, Lieke , Hotz-Wagenblatt, Agnes, Wuttke, Marina , Schambeck, Kathrin , Ruhland, Brigitte , Hofmann, Veronika , Bittner, Sebastian , Ritter, Uwe , Pant, Asmita , Helbich, Sara Salome, Voss, Morten, Lemmermann, Niels A., Bessiri-Schake, Lisa, Bohn, Toszka, Eigenberger, Andreas , Menevse, Ayse Nur , Gebhard, Claudia , Strieder, Nicholas , Abken, Hinrich , Rehli, Michael , Huehn, Jochen, Beckhove, Philipp , Hehlgans, Thomas , Junger, Henrik , Geissler, Edward K. , Prantl, Lukas , Werner, Jens M. , Schmidl, Christian , Brors, Benedikt, Imbusch, Charles D. and Feuerer, Markus (2024) The effector program of human CD8 T cells supports tissue remodeling. Journal of Experimental Medicine 221 (2), e20230488.

Harrer, Dennis Christoph , Li, Sin-Syue, Kaljanac, Marcell, Barden, Markus, Pan, Hong and Abken, Hinrich (2023) Fine-tuning the antigen sensitivity of CAR T cells: emerging strategies and current challenges. Frontiers in Immunology 14.

Harrer, Dennis Christoph , Bezler, Valerie, Hartley, Jordan, Herr, Wolfgang and Abken, Hinrich (2023) IRF4 downregulation improves sensitivity and endurance of CAR T cell functional capacities. Frontiers in Immunology 14.

Thomas, Simone and Abken, Hinrich (2023) CAR T cell therapy becomes CHIC: “cytokine help intensified CAR” T cells. Frontiers in Immunology 13.

Kaljanac, Marcell and Abken, Hinrich (2023) Do Treg Speed Up with CARs? Chimeric Antigen Receptor Treg Engineered to Induce Transplant Tolerance. Transplantation 107 (1), pp. 74-85.

Hombach, Andreas A., Ambrose, Christine, Lobb, Roy, Rennert, Paul and Abken, Hinrich (2023) A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2+ Solid Cancer. Cells 12 (2), p. 248. Fulltext not available.

Altvater, Bianca, Kailayangiri, Sareetha, Spurny, Christian, Flügge, Maike, Meltzer, Jutta, Greune, Lea, Urban, Katja, Schwöppe, Christian, Brand, Caroline, Schliemann, Christoph, Hintelmann, Heike, Harrach, Saliha, Hartmann, Wolfgang, Abken, Hinrich, Kuehle, Johannes, Schambach, Axel, Görlich, Dennis, Berdel, Wolfgang E. and Rossig, Claudia (2023) CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process. Cancer Gene Therapy 30 (10), pp. 1355-1368. Fulltext not available.

Barden, Markus, Holzinger, Astrid, Velas, Lukas, Mezősi-Csaplár, Marianna, Szöőr, Árpád, Vereb, György, Schütz, Gerhard J., Hombach, Andreas A. and Abken, Hinrich (2023) CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activation. Frontiers in Immunology 14. Fulltext not available.

Ciulean, Ioana Sonya, Fischer, Joe, Quaiser, Andrea, Bach, Christoph, Abken, Hinrich, Tretbar, Uta Sandy, Fricke, Stephan, Koehl, Ulrike, Schmiedel, Dominik and Grunwald, Thomas (2023) CD44v6 specific CAR-NK cells for targeted immunotherapy of head and neck squamous cell carcinoma. Frontiers in Immunology 14. Fulltext not available.

Soto, Karla E. G., Loureiro, Liliana R., Bartsch, Tabea, Arndt, Claudia, Kegler, Alexandra, Mitwasi, Nicola, Drewitz, Laura, Hoffmann, Lydia, Saleh, Haidy A., Crespo, Eugenia, Mehnert, Maria, Daglar, Cansu, Abken, Hinrich, Momburg, Frank, Bachmann, Michael and Feldmann, Anja (2023) Targeting colorectal cancer cells using AND-gated adaptor RevCAR T-cells. Frontiers in Immunology 14. Fulltext not available.

Harrer, Dennis Christoph , Schenkel, Charlotte, Bezler, Valerie, Kaljanac, Marcell, Hartley, Jordan, Barden, Markus, Pan, Hong, Holzinger, Astrid, Herr, Wolfgang and Abken, Hinrich (2022) CAR Triggered Release of Type-1 Interferon Limits CAR T-Cell Activities by an Artificial Negative Autocrine Loop. Cells 11 (23), p. 3839.

Holzinger, Astrid and Abken, Hinrich (2022) Treatment with Living Drugs: Pharmaceutical Aspects of CAR T Cells. Pharmacology 107 (9-10), pp. 446-463.

Garofano, Francesca , Sharma, Amit , Abken, Hinrich, Gonzalez-Carmona, Maria A. and Schmidt-Wolf, Ingo G. H. (2022) A Low Dose of Pure Cannabidiol Is Sufficient to Stimulate the Cytotoxic Function of CIK Cells without Exerting the Downstream Mediators in Pancreatic Cancer Cells. International Journal of Molecular Sciences 23 (7), p. 3783. Fulltext not available.

Harrer, Dennis Christoph, Schenkel, Charlotte, Berking, Carola, Herr, Wolfgang, Abken, Hinrich , Dörrie, Jan and Schaft, Niels (2022) Decitabine-Mediated Upregulation of CSPG4 in Ovarian Carcinoma Cells Enables Targeting by CSPG4-Specific CAR-T Cells. Cancers 14 (20), p. 5033. Fulltext not available.

Balta, Emre, Janzen, Nina, Kirchgessner, Henning, Toufaki, Vasiliki, Orlik, Christian, Liang, Jie, Lairikyengbam, Divya, Abken, Hinrich, Niesler, Beate, Müller-Decker, Karin, Ruppert, Thomas and Samstag, Yvonne (2022) Expression of TRX1 optimizes the antitumor functions of human CAR T cells and confers resistance to a pro-oxidative tumor microenvironment. Frontiers in Immunology 13. Fulltext not available.

Hombach, Andreas, Barden, Markus, Hannappel, Lisa, Chmielewski, Markus, Rappl, Gunter, Sachinidis, Agapios and Abken, Hinrich (2022) IL12 integrated into the CAR exodomain converts CD8+ T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors. Molecular Therapy 30 (2), pp. 593-605. Fulltext not available.

Ramos, Joe W., Ambrose, Christine, Su, Lihe, Wu, Lan, Dufort, Fay J., Sanford, Thomas, Birt, Alyssa, Hackel, Benjamin J., Hombach, Andreas, Abken, Hinrich, Lobb, Roy R. and Rennert, Paul D. (2021) Anti-CD19 CAR T cells potently redirected to kill solid tumor cells. PLOS ONE 16 (3), e0247701. Fulltext not available.

Köhl, Ulrike and Abken, Hinrich (2021) CAR-T-Zellen als Arzneimittel für neuartige Therapien (Advanced Therapy Medicinal Products). Der Internist 62 (4), pp. 449-457. Fulltext not available.

Bunse, Mario, Pfeilschifter, Janina, Bluhm, Julia, Zschummel, Maria, Joedicke, Jara J., Wirges, Anthea, Stark, Helen, Kretschmer, Vivien, Chmielewski, Markus, Uckert, Wolfgang, Abken, Hinrich , Westermann, Jörg, Rehm, Armin and Höpken, Uta E. (2021) CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells. Nature Communications 12 (1). Fulltext not available.

Rudek, Loreen Sophie, Zimmermann, Katharina, Galla, Melanie, Meyer, Johann, Kuehle, Johannes, Stamopoulou, Andriana, Brand, Daniel, Sandalcioglu, I. Erol, Neyazi, Belal, Moritz, Thomas, Rossig, Claudia, Altvater, Bianca, Falk, Christine S., Abken, Hinrich, Morgan, Michael Alexander and Schambach, Axel (2021) Generation of an NFκB-Driven Alpharetroviral “All-in-One” Vector Construct as a Potent Tool for CAR NK Cell Therapy. Frontiers in Immunology 12. Fulltext not available.

Hombach, Andreas A., Geumann, Ulf, Günther, Christine, Hermann, Felix G. and Abken, Hinrich (2020) IL7-IL12 Engineered Mesenchymal Stem Cells (MSCs) Improve A CAR T Cell Attack Against Colorectal Cancer Cells. Cells 9 (4), p. 873.

Tóth, G., Szöllősi, J. and Abken, Hinrich (2020) A Small Number of HER2 Redirected CAR T Cells Significantly Improves Immune Response of Adoptively Transferred Mouse Lymphocytes against Human Breast Cancer Xenografts. International Journal of Molecular Sciences 21 (3), p. 1039.

Dragon, Anna Christina , Zimmermann, Katharina, Nerreter, Thomas, Sandfort, Deborah, Lahrberg, Julia, Klöß, Stephan, Kloth, Christina, Mangare, Caroline, Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Uchanska-Ziegler, Barbara, Abken, Hinrich, Schambach, Axel, Hudecek, Michael and Eiz-Vesper, Britta (2020) CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation. Journal for ImmunoTherapy of Cancer 8 (2), e000736. Fulltext not available.

Nemade, Harshal, Acharya, Aviseka, Chaudhari, Umesh , Nembo, Erastus, Nguemo, Filomain , Riet, Nicole, Abken, Hinrich, Hescheler, Jürgen, Papadopoulos, Symeon and Sachinidis, Agapios (2020) Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells. Cells 9 (3), p. 554. Fulltext not available.

Zimmermann, Katharina, Kuehle, Johannes, Dragon, Anna Christina , Galla, Melanie, Kloth, Christina, Rudek, Loreen Sophie, Sandalcioglu, I. Erol, Neyazi, Belal, Moritz, Thomas, Meyer, Johann, Rossig, Claudia, Altvater, Bianca, Eiz-Vesper, Britta, Morgan, Michael Alexander, Abken, Hinrich and Schambach, Axel (2020) Design and Characterization of an “All-in-One” Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines. Cancers 12 (2), p. 375. Fulltext not available.

Patasic, Lea, Seifried, Janna, Bezler, Valerie, Kaljanac, Marcell, Schneider, Irene C., Schmitz, Heike, Tondera, Christiane, Hartmann, Jessica, Hombach, Andreas, Buchholz, Christian J., Abken, Hinrich, König, Renate and Cichutek, Klaus (2020) Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4+ T cells to reduce the latent HIV+ cell reservoir. Medical Microbiology and Immunology 209 (6), pp. 681-691. Fulltext not available.

Beckhove, Philipp , Edinger, Matthias, Feuerer, Markus, Gattinoni, Luca and Abken, Hinrich (2020) International Regensburg Center for Interventional Immunology (RCI) symposium on “Synthetic immunology and environment-adapted redirection of T cells”, 17–18 July, 2019, Regensburg, Germany. Cancer Immunology, Immunotherapy 69, pp. 677-682.

Haumann, Sophie, Boix, Julia, Knuever, Jana, Bieling, Angela, Vila Sanjurjo, Anton, Elson, Joanna L., Blakely, Emma L., Taylor, Robert W., Riet, Nicole, Abken, Hinrich, Kashkar, Hamid, Hornig-Do, Hue-Tran and Wiesner, Rudolf J. (2020) Mitochondrial DNA mutations induce mitochondrial biogenesis and increase the tumorigenic potential of Hodgkin and Reed–Sternberg cells. Carcinogenesis 41 (12), pp. 1735-1745. Fulltext not available.

Alzubi, Jamal, Dettmer-Monaco, Viviane, Kuehle, Johannes, Thorausch, Niko, Seidl, Maximilian, Taromi, Sanaz, Schamel, Wolfgang, Zeiser, Robert, Abken, Hinrich, Cathomen, Toni and Wolf, Philipp (2020) PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model. Molecular Therapy - Oncolytics 18, pp. 226-235. Fulltext not available.

Chmielewski, Markus and Abken, Hinrich (2020) TRUCKS, the fourth generation CAR T cells: current developments and clinical translation. Advances in Cell and Gene Therapy 3, e84.

Szöőr, Árpád, Tóth, Gábor, Zsebik, Barbara, Szabó, Viktória, Eshhar, Zelig, Abken, Hinrich and Vereb, György (2020) Trastuzumab derived HER2-specific CARs for the treatment of trastuzumab-resistant breast cancer: CAR T cells penetrate and eradicate tumors that are not accessible to antibodies. Cancer Letters 484, pp. 1-8. Fulltext not available.

Hombach, Andreas A., Rappl, Gunter and Abken, Hinrich (2019) Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30− Tumors. Molecular Therapy 27 (10), pp. 1825-1835. Fulltext not available.

Chmielewski, Markus, Kuehle, Johannes, Chrobok, Danuta, Riet, Nicole, Hallek, Michael and Abken, Hinrich (2019) FimH-based display of functional eukaryotic proteins on bacteria surfaces. Scientific Reports 9 (1). Fulltext not available.

Aleksandrova, Krasimira, Leise, Jana, Priesner, Christoph, Melk, Anette, Kubaink, Fanni, Abken, Hinrich, Hombach, Andreas, Aktas, Murat, Essl, Mike, Bürger, Iris, Kaiser, Andrew, Rauser, Georg, Jurk, Marion, Goudeva, Lilia, Glienke, Wolfgang, Arseniev, Lubomir, Esser, Ruth and Köhl, Ulrike (2019) Functionality and Cell Senescence of CD4/ CD8-Selected CD20 CAR T Cells Manufactured Using the Automated CliniMACS Prodigy® Platform. Transfusion Medicine and Hemotherapy 46 (1), pp. 47-54. Fulltext not available.

Golumba-Nagy, Viktória, Kuehle, Johannes, Hombach, Andreas A. and Abken, Hinrich (2018) CD28-ζ CAR T Cells Resist TGF-β Repression through IL-2 Signaling, Which Can Be Mimicked by an Engineered IL-7 Autocrine Loop. Molecular Therapy 26 (9), pp. 2218-2230. Fulltext not available.

Probst, Kristina, Stermann, Jacek, von Bomhard, Inga, Etich, Julia , Pitzler, Lena, Niehoff, Anja, Bluhm, Björn, Xu, Haifeng C., Lang, Philipp A., Chmielewski, Markus, Abken, Hinrich, Blissenbach, Birgit, Machova, Alzbeta, Papadopoulou, Nikoletta and Brachvogel, Bent (2018) Depletion of Collagen IX Alpha1 Impairs Myeloid Cell Function. STEM CELLS 36 (11), pp. 1752-1763. Fulltext not available.