Publikationen von Klein, Christoph A.

Treitschke, Steffi, Weidele, Kathrin, Varadarajan, Adithi Ravikumar, Feliciello, Giancarlo, Warfsmann, Jens, Vorbeck, Sybille, Polzer, Bernhard, Botteron, Catherine, Hoffmann, Martin, Dechand, Vadim, Mederer, Tobias , Weber, Florian , Werner‐Klein, Melanie, Robold, Tobias, Hofmann, Hans‐Stefan, Werno, Christian und Klein, Christoph A. (2023) Ex vivo expansion of lung cancer‐derived disseminated cancer cells from lymph nodes identifies cells associated with metastatic progression. International Journal of Cancer.

Elsner, Felix, Hoffmann, Martin, Fahrioglu‐Yamaci, Rezan, Czyz, Zbigniew, Feliciello, Giancarlo, Mederer, Tobias , Polzer, Bernhard, Treitschke, Steffi, Rümmele, Petra, Weber, Florian , Wiesinger, Hellmuth, Robold, Tobias, Sziklavari, Zsolt, Sienel, Wulf, Hofmann, Hans‐Stefan und Klein, Christoph A. (2022) Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution. The Journal of Pathology 258 (3), S. 250-263.

Mederer, Tobias, Elsner, Felix, Robold, Tobias, Großer, Christian, Neu, Reiner, Ried, Michael, Bleicher, Sabine, Schamberger, Thomas, Blochberger, Isabell, Hofmann, Hans-Stefan und Klein, Christoph A. (2022) EpCAM-positive disseminated cancer cells in bone marrow impact on survival of early-stage NSCLC patients. Lung Cancer 167, S. 73-77.

Metzenmacher, Martin, Hegedüs, Balazs , Forster, Jan, Schramm, Alexander, Horn, Peter A., Klein, Christoph A., Bielefeld, Nicola, Ploenes, Till, Aigner, Clemens, Theegarten, Dirk, Schildhaus, Hans-Ulrich, Siveke, Jens T., Schuler, Martin und Lueong, Smiths S. (2022) Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer. Translational Oncology 15 (1), S. 101279. Volltext nicht vorhanden.

Metzenmacher, Martin , Hegedüs, Balazs, Forster, Jan, Schramm, Alexander, Horn, Peter A., Klein, Christoph A., Bielefeld, Nicola, Ploenes, Till, Aigner, Clemens, Siveke, Jens T., Schuler, Martin und Lueong, Smiths S. (2022) The clinical utility of cfRNA for disease detection and surveillance: A proof of concept study in non‐small cell lung cancer. Thoracic Cancer 13 (15), S. 2180-2191. Volltext nicht vorhanden.

Drexler, Konstantin, Schmidt, Katharina M., Jordan, Katrin , Federlin, Marianne, Milenkovic, Vladimir M., Liebisch, Gerhard , Artati, Anna, Schmidl, Christian , Madej, Gregor , Tokarz, Janina , Cecil, Alexander, Jagla, Wolfgang, Haerteis, Silke, Aung, Thiha, Wagner, Christine, Kolodziejczyk, Maria, Heinke, Stefanie, Stanton, Evan H., Schwertner, Barbara, Riegel, Dania, Wetzel, Christian H. , Buchalla, Wolfgang, Proescholdt, Martin, Klein, Christoph A., Berneburg, Mark, Schlitt, Hans J., Brabletz, Thomas, Ziegler, Christine , Parkinson, Eric K., Gaumann, Andreas, Geissler, Edward K., Adamski, Jerzy , Haferkamp, Sebastian und Mycielska, Maria E. (2021) Cancer-associated cells release citrate to support tumour metastatic progression. Life Science Alliance 4 (6), e202000903.

Silvestri, Marco , Reduzzi, Carolina , Feliciello, Giancarlo, Vismara, Marta, Schamberger, Thomas, Köstler, Cäcilia, Motta, Rosita, Calza, Stefano , Ferraris, Cristina, Vingiani, Andrea , Pruneri, Giancarlo , Daidone, Maria Grazia, Klein, Christoph A., Polzer, Bernhard und Cappelletti, Vera (2021) Detection of Genomically Aberrant Cells within Circulating Tumor Microemboli (CTMs) Isolated from Early-Stage Breast Cancer Patients. Cancers 13 (6), S. 1409. Volltext nicht vorhanden.

Hartkopf, Andreas D., Brucker, Sara Y., Taran, Florin-Andrei, Harbeck, Nadia, von Au, Alexandra, Naume, Bjørn, Pierga, Jean-Yves, Hoffmann, Oliver, Beckmann, Matthias W., Rydén, Lisa, Fehm, Tanja, Aft, Rebecca, Solà, Montserrat, Walter, Vincent, Rack, Brigitte, Schuetz, Florian, Borgen, Elin, Ta, Minh-Hanh, Bittner, Ann-Kathrin, Fasching, Peter A., Fernö, Mårten, Krawczyk, Natalia, Weilbaecher, Katherine, Margelí, Mireia, Hahn, Markus, Jueckstock, Julia, Domschke, Christoph, Bidard, Francois-Clement, Kasimir-Bauer, Sabine, Schoenfisch, Birgitt, Kurt, Ayse G., Wallwiener, Markus, Gebauer, Gerhard, Klein, Christoph A., Wallwiener, Diethelm, Janni, Wolfgang und Pantel, Klaus (2021) Disseminated tumour cells from the bone marrow of early breast cancer patients: Results from an international pooled analysis. European Journal of Cancer 154, S. 128-137. Volltext nicht vorhanden.

Hücker, Sarah M., Fehlmann, Tobias, Werno, Christian, Weidele, Kathrin, Lüke, Florian, Schlenska-Lange, Anke, Klein, Christoph A., Keller, Andreas und Kirsch, Stefan (2021) Single-cell microRNA sequencing method comparison and application to cell lines and circulating lung tumor cells. Nature Communications 12 (1). Volltext nicht vorhanden.

Werner-Klein, Melanie, Grujovic, Ana, Irlbeck, Christoph, Obradović, Milan, Hoffmann, Martin, Koerkel-Qu, Huiqin, Lu, Xin, Treitschke, Steffi, Köstler, Cäcilia, Botteron, Catherine, Weidele, Kathrin, Werno, Christian, Polzer, Bernhard, Kirsch, Stefan , Gužvić, Miodrag, Warfsmann, Jens, Honarnejad, Kamran, Czyz, Zbigniew, Feliciello, Giancarlo, Blochberger, Isabell, Grunewald, Sandra, Schneider, Elisabeth, Haunschild, Gundula, Patwary, Nina, Guetter, Severin, Huber, Sandra, Rack, Brigitte, Harbeck, Nadia, Buchholz, Stefan, Rümmele, Petra, Heine, Norbert, Rose-John, Stefan und Klein, Christoph A. (2020) Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency. Nature Communications 11, S. 4977.

Metzenmacher, M., Váraljai, R. , Hegedüs, B., Klein, Christoph A., make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference , make_name_string expected hash reference, make_name_string expected hash reference , make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference und make_name_string expected hash reference (2020) Plasma next generation sequencing and droplet digital-qPCR-based quantification of circulating cell-free RNA for noninvasive early detection of cancer. Cancers 12, S. 353.

Klein, Christoph A. (2020) Cancer progression and the invisible phase of metastatic colonization. Nature Reviews Cancer 20 (11), S. 681-694. Volltext nicht vorhanden.

Vollmann-Zwerenz, Arabel, Leidgens, Verena, Feliciello, Giancarlo, Klein, Christoph A. und Hau, Peter (2020) Tumor Cell Invasion in Glioblastoma. International Journal of Molecular Sciences 21 (6), S. 1932. Volltext nicht vorhanden.

Durst, Franziska C., Grujovic, Ana , Ganser, Iris, Hoffmann, Martin, Ugocsai, Peter, Klein, Christoph A. und Czyż, Zbigniew T. (2019) Targeted transcript quantification in single disseminated cancer cells after whole transcriptome amplification. PLOS ONE 14 (8), e0216442.

Alieva, Maria, Leidgens, Verena, Riemenschneider, Markus J., Klein, Christoph A., Hau, Peter und van Rheenen, Jacco (2019) Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion. Scientific Reports 9 (2054), S. 1-11.

Weidele, Kathrin, Stojanović, Nataša, Feliciello, Giancarlo, Markiewicz, Aleksandra, Scheitler, Sebastian, Alberter, Barbara, Renner, Philipp, Haferkamp, Sebastian, Klein, Christoph A. und Polzer, Bernhard (2019) Microfluidic enrichment, isolation and characterization of disseminated melanoma cells from lymph node samples. International Journal of Cancer 145 (1), S. 232-241. Volltext nicht vorhanden.

Werner-Klein, Melanie, Scheitler, Sebastian, Hoffmann, Martin, Hodak, Isabelle, Dietz, Klaus , Lehnert, Petra, Naimer, Veronika, Polzer, Bernhard , Treitschke, Steffi, Werno, Christian, Markiewicz, Aleksandra, Weidele, Kathrin, Czyz, Zbigniew, Hohenleutner, Ulrich, Hafner, Christian, Haferkamp, Sebastian, Berneburg, Mark, Rümmele, Petra, Ulmer, Anja und Klein, Christoph A. (2018) Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma. Nature Communications 9 (595), S. 1-17.

Lorentzen, Anna , Becker, Paul F., Kosla, Jan, Saini, Massimo, Weidele, Kathrin, Ronchi, Paolo, Klein, Corinna, Wolf, Monika J., Geist, Felix, Seubert, Bastian, Ringelhan, Marc, Mihic-Probst, Daniela, Esser, Knud, Roblek, Marko, Kuehne, Felix, Bianco, Gaia, O’Connor, Tracy, Müller, Quentin, Schuck, Kathleen, Lange, Sebastian , Hartmann, Daniel, Spaich, Saskia, Groß, Olaf, Utikal, Jochen , Haferkamp, Sebastian, Sprick, Martin R., Damle-Vartak, Amruta, Hapfelmeier, Alexander , Hüser, Norbert, Protzer, Ulrike , Trumpp, Andreas , Saur, Dieter, Vartak, Nachiket, Klein, Christoph A., Polzer, Bernhard, Borsig, Lubor und Heikenwalder, Mathias (2018) Single cell polarity in liquid phase facilitates tumour metastasis. Nature Communications 9 (1). Volltext nicht vorhanden.

Ulmer, Anja, Dietz, Klaus , Werner-Klein, Melanie, Häfner, Hans-Martin, Schulz, Claudia, Renner, Philipp, Weber, Florian, Breuninger, Helmut, Röcken, Martin, Garbe, Claus , Fierlbeck, Gerhard und Klein, Christoph A. (2018) The sentinel lymph node spread determines quantitatively melanoma seeding to non-sentinel lymph nodes and survival. European Journal of Cancer 91, S. 1-10. Volltext nicht vorhanden.

Hoffmann, Martin, Pasch, Sophie, Schamberger, Thomas, Maneck, Matthias, Möhlendick, Birte, Schumacher, Sarah, Brockhoff, Gero, Knoefel, Wolfram Trudo, Izbicki, Jakob, Polzer, Bernhard, Stoecklein, Nikolas H. und Klein, Christoph A. (2017) Diagnostic pathology of early systemic cancer:ERBB2gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer. International Journal of Cancer 142 (4), S. 833-843. Volltext nicht vorhanden.

Schumacher, Sarah, Bartenhagen, Christoph, Hoffmann, Martin, Will, Daniel, Fischer, Johannes C., Baldus, Stephan E., Vay, Christian, Fluegen, Georg, Dizdar, Levent, Vallböhmer, Daniel, Klein, Christoph A., Knoefel, Wolfram T., Stoecklein, Nikolas H. und Möhlendick, Birte (2017) Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma. British Journal of Cancer 117 (5), S. 725-733. Volltext nicht vorhanden.

Hosseini, H., Obradovic, M. M., Hoffmann, M., Harper, K. L., Sosa, M. S., Werner-Klein, M., Nanduri, L. K. , Werno, C., Ehrl, C., Maneck, M., Patwary, N., Haunschild, G., Guzvic, M., Reimelt, C., Grauvogl, Michael, Eichner, N., Weber, F., Hartkopf, A. D., Taran, F. A., Brucker, S. Y., Fehm, T., Rack, B., Buchholz, S., Spang, Rainer, Meister, Gunter, Aguirre-Ghiso, J. A. und Klein, Christoph A. (2016) Early dissemination seeds metastasis in breast cancer. Nature 540, S. 552-558. Volltext nicht vorhanden.

Harper, Kathryn L., Sosa, Maria Soledad, Entenberg, David , Hosseini, Hedayatollah, Cheung, Julie F., Nobre, Rita, Avivar-Valderas, Alvaro, Nagi, Chandandaneep, Girnius, Nomeda , Davis, Roger J., Farias, Eduardo F., Condeelis, John, Klein, Christoph A. und Aguirre-Ghiso, Julio A. (2016) Mechanism of early dissemination and metastasis in Her2+ mammary cancer. Nature 540 (7634), S. 588-592. Volltext nicht vorhanden.

Suzuki, Toru , Asami, Maki, Hoffmann, Martin , Lu, Xin, Gužvić, Miodrag, Klein, Christoph A. und Perry, Anthony C. F. (2016) Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes. Nature Communications 7 (1). Volltext nicht vorhanden.

Gužvić, Miodrag und Klein, Christoph A. (2016) Towards prevention of metastatic prostate cancer: recent molecular insights from the direct analysis of metastatic precursor cells. Translational Cancer Research 5 (S2), S182-S186. Volltext nicht vorhanden.

Werner-Klein, Melanie, Proske, Judith, Werno, Christian, Schneider, Katharina, Hofmann, Hans-Stefan, Rack, Brigitte, Buchholz, Stefan, Ganzer, Roman, Blana, Andreas, Seelbach-Göbel, Birgit, Nitsche, Ulrich, Männel, Daniela N. und Klein, Christoph A. (2014) Immune Humanization of Immunodeficient Mice Using Diagnostic Bone Marrow Aspirates from Carcinoma Patients. PLoS ONE 9 (5), e97860.

Ulmer, Anja, Dietz, Klaus, Hodak, Isabelle, Polzer, Bernhard, Scheitler, Sebastian, Yildiz, Murat, Czyz, Zbigniew, Lehnert, Petra, Fehm, Tanja, Hafner, Christian, Schanz, Stefan, Röcken, Martin, Garbe, Claus, Breuning, Helmut, Fierlbeck, Gerhard und Klein, Christoph A. (2014) Quantitative Measurement of Melanoma Spread in Sentinel Lymph Nodes and Survival. PLoS ONE 11 (2), e001604.

Czyż, Zbigniew T., Hoffmann, Martin, Schlimok, G., Polzer, Bernhard und Klein, Christoph A. (2014) Reliable Single Cell Array CGH for Clinical Samples. Plos One 9 (1).

Hittinger, Markus, Zbigniew, Czyz T., Huesemann, Yves, Maneck, Matthias, Botteron, Catherine, Kaeufl, Stephanie, Klein, Christoph A. und Polzer, Bernhard (2013) Molecular profiling of single Sca-1+/CD34+,- cells - the putative murine lung stem cells. PLoS ONE 8 (12), e83917.

VerMilyea, Matthew, Maneck, Matthias, Yoshida, Naoko, Blochberger, Isabell, Suzuki, Emi, Suzuki, Toru, Spang, Rainer, Klein, Christoph A. und Perry, Anthony C. F. (2011) Transcriptome asymmetry within mouse zygotes but not between early embryonic sister blastomeres. The EMBO journal 30 (9), S. 1841-1851. Volltext nicht vorhanden.

Chambers, Karen F., Pearson, Joanna F., Pellacani, Davide, Aziz, Naveed, Gužvić, Miodrag, Klein, Christoph A. und Lang, Shona H. (2011) Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium. Journal of biomedical science 18, S. 45.