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Babl, Nathalie
, Voll, Florian, Martowicz, Agnieszka, Bruss, Christina, Maddaloni, Marianna, Schmidl, Christian
, Rehli, Michael
, Loipfinger, Stefan, Strieder, Nicholas
, Gebhard, Claudia
, Hoffmann, Petra, Singh, Sukh M., Sala-Hojman, Ada, Ferretti, Roberta, Matos, Carina
, Simon, Malte
, Brummer, Christina, Schnell, Annette
, Hofbauer, Joshua, Decking, Sonja-Maria, Hau, Peter
, Vollmann-Zwerenz, Arabel, Dettmer, Katja
, Oefner, Peter J.
, Althammer, Michael, Laufs, Johanna, Friedl, Sarah, Heinrich, Timo, Herhaus, Christian, Evert, Katja
, Mayr, Roman
, Afonso, Julieta, Baltazar, Fatima, Herr, Wolfgang, Siska, Peter J.
, Renner, Kathrin
and Kreutz, Marina
(2025)
Lactic acid promotes an MDSC-like phenotype via HIF1α stabilization with impact on prognosis in renal cell carcinoma.
Cancer Letters 639, p. 218209.
Göttert, Sascha, Thiele Orberg, Erik
, Fan, Kaiji, Heinrich, Paul
, Matthe, Diana M., Khalid, Omer, Klostermeier, Lena, Suriano, Chiara, Strieder, Nicholas
, Gebhard, Claudia
, Vonbrunn, Eva, Mamilos, Andreas
, Hirsch, Daniela, Meedt, Elisabeth, Kleigrewe, Karin, Hiergeist, Andreas
, Schwarz, Alix, Gläsner, Joachim, Ghimire, Sakhila, Joachim, Laura, Voll, Florian, Neuhaus, Klaus, Janssen, Klaus-Peter, Perl, Markus, Pielmeier, Franziska, Ruland, Jürgen, Kreutz, Marina
, Weber, Daniela, Schmidl, Christian
, Köhler, Natalie, Tschurtschenthaler, Markus, Hoffmann, Petra, Edinger, Matthias
, Wolff, Daniel
, Bassermann, Florian, Rehli, Michael
, Haller, Dirk, Evert, Matthias, Hildner, Kai, Büttner-Herold, Maike, Herr, Wolfgang, Gessner, André
, Heidegger, Simon, Holler, Ernst
and Poeck, Hendrik
(2025)
The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration.
Nature Communications 16 (1).
Simeth, Jakob
, Engelmann, Simon, Mayr, Roman
, Kaelble, Sebastian, Weber, Florian
, Pichler, Renate, Dettmer, Katja
, Oefner, Peter J.
, Höring, Marcus
, Symeou, Luisa, Freitag, Katharina, Wagner, Kilian, Burger, Maximilian, Herr, Wolfgang, Kreutz, Marina
, Spang, Rainer
, Liebisch, Gerhard
and Siska, Peter J.
(2025)
Lipid metabolism of clear cell renal cell carcinoma predicts survival and affects intratumoral CD8 T cells.
Translational Oncology 61, p. 102513.
Teubner, Jan P., Tümen, Deniz, Kandulski, Arne, Heumann, Philipp, Mester, Patricia, Aschenbrenner, Elisabeth, Pollinger, Kirstin, Gunckel, Manuela, Volz, Barbara, Hein, Tobias, Beltzig, Paul L., Tengler, Luisa, Voll, Florian, Kreutz, Marina, Kunst, Claudia, Nicolay, Jan P., Müller, Martina and Gülow, Karsten
(2025)
CRISPR‐Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl‐fumarate‐induced cell death.
The FEBS Journal.
Weich, Laura, Brummer, Christina, Ghimire, Sakhila, Peter, Katrin
, Althammer, Michael, Babl, Nathalie
, Voll, Florian, Bruss, Christina, Hoering, Marcus, Wallner, Stefan
, Siska, Peter J.
, Holler, Ernst, Herr, Wolfgang, Bruns, Heiko, Heid, Iris M., Stark, Klaus J., Kreutz, Marina
and Matos, Carina
(2025)
Impact of Liver and Kidney Function on Vitamin D3 Metabolism in Female and Male Patients Undergoing Allogeneic Hematopoietic Stem-Cell Transplantation.
International Journal of Molecular Sciences 26 (7), p. 2866.
Brummer, Christina, Singer, Katrin, Renner, Kathrin
, Bruss, Christina, Hellerbrand, Claus
, Dorn, Christoph
, Reichelt-Wurm, Simone
, Gronwald, Wolfram
, Pukrop, Tobias
, Herr, Wolfgang, Banas, Miriam C.
and Kreutz, Marina
(2025)
The spleen-liver axis supports obesity-induced systemic and fatty liver inflammation via MDSC and NKT cell enrichment.
Molecular and cellular endocrinology 601, p. 112518.
Brummer, Christina, Singer, Katrin, Henrich, Frederik, Peter, Katrin
, Strobl, Carolin Dorothea
, Neueder, Bernadette, Bruss, Christina, Renner, Kathrin
, Pukrop, Tobias
, Herr, Wolfgang, Aigner, Michael and Kreutz, Marina
(2024)
The Tumor Metabolite 5′-Deoxy-5′Methylthioadenosine (MTA) Inhibits Maturation and T Cell-Stimulating Capacity of Dendritic Cells.
Cells 13 (24), p. 2114.
Brummer, Christina, Singer, Katrin, Brand, Almut, Bruss, Christina, Renner, Kathrin, Herr, Wolfgang, Pukrop, Tobias, Dorn, Christoph
, Hellerbrand, Claus, Matos, Carina and Kreutz, Marina
(2024)
Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity.
International Journal of Molecular Sciences 25 (15), p. 8234.
Schreiber, Laura, Ghimire, Sakhila, Hiergeist, Andreas
, Renner, Kathrin
, Althammer, Michael, Babl, Nathalie, Peuker, Alice, Schoenhammer, Gabriele, Hippe, Katrin, Gessner, Andre
, Albrecht, Christian, Pielmeier, Fransziska, Büttner-Herold, Maike, Bruns, Heiko, Hoffmann, Petra, Herr, Wolfgang, Holler, Ernst, Peter, Katrin
, Kreutz, Marina
and Matos, Carina
(2024)
Strain specific differences in vitamin D3 response: impact on gut homeostasis.
Frontiers in Immunology 15.
Hammon, Kathrin, Renner, Kathrin, Althammer, Michael, Voll, Florian, Babl, Nathalie, Decking, Sonja-Maria, Siska, Peter J.
, Matos, Carina, Conejo, Zugey Elizabeth Cárdenas, Mendes, Karina
, Einwag, Friederike, Siegmund, Heiko, Iberl, Sabine, Berger, Raffaela S.
, Dettmer, Katja, Schoenmehl, Rebecca, Brochhausen, Christoph
, Herr, Wolfgang, Oefner, Peter J.
, Rehli, Michael
, Thomas, Simone
and Kreutz, Marina
(2024)
D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells.
Haematologica.
Babl, Nathalie, Decking, Sonja-Maria, Voll, Florian, Althammer, Michael, Sala-Hojman, Ada, Ferretti, Roberta, Korf, Clarissa, Schmidl, Christian, Schmidleithner, Lisa, Nerb, Benedikt, Matos, Carina
, Koehl, Gudrun E., Siska, Peter J.
, Bruss, Christina, Kellermeier, Fabian, Dettmer, Katja
, Oefner, Peter J.
, Wichland, Marvin, Ugele, Ines, Bohr, Christopher, Herr, Wolfgang, Ramaswamy, Shivapriya, Heinrich, Timo, Herhaus, Christian, Kreutz, Marina
and Renner, Kathrin
(2023)
MCT4 blockade increases the efficacy of immune checkpoint blockade.
Journal for ImmunoTherapy of Cancer 11 (10), e007349.
Schoeppe, Robert, Babl, Nathalie, Decking, Sonja-Maria, Schönhammer, Gabriele, Siegmund, Andreas, Bruss, Christina, Dettmer, Katja
, Oefner, Peter J.
, Frick, Linus, Weigert, Anna, Jantsch, Jonathan, Herr, Wolfgang, Rehli, Michael
, Renner, Kathrin
and Kreutz, Marina
(2023)
Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment.
Frontiers in Oncology 13, pp. 1-12.
, Ugele, Ines, Werner, Jens M.
, Siska, Peter J. and Schmidl, Christian
(2023)
Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8+ T cells.
Molecular Cell 83 (4), 622-636.e10.
Fulltext not available.
Babl, Nathalie, Hofbauer, Joshua, Matos, Carina
, Voll, Florian, Menevse, Ayse Nur, Rechenmacher, Michael, Mair, Ruth, Beckhove, Philipp
, Herr, Wolfgang, Siska, Peter J.
, Renner, Kathrin
, Kreutz, Marina
and Schnell, Annette
(2023)
Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.
Frontiers in Oncology 13.
, Renner, Kathrin, Kreutz, Marina and Gattinoni, Luca
(2023)
Targeting lactate metabolism for cancer immunotherapy - a matter of precision.
Seminars in Cancer Biology 88, pp. 32-45.
Fulltext not available.
, Künzel, Julian
, Oefner, Peter J., Kreutz, Marina, Bohr, Christopher and Renner, Kathrin
(2023)
Zusammenspiel von Tumormetabolismus und Immuninfiltrat im Kopf-Hals-Plattenepithelkarzinom.
In: 94. Jahresversammlung Deutsche Gesellschaft für Hals-NasenOhren-Heilkunde, Kopf- und Hals-Chirugie e.V., Bonn, 17.-20. Mai 2023, Leipzig.
Fulltext not available.
Matos, Carina, Mamilos, Andreas, Shah, Pranali N., Meedt, Elisabeth, Weber, Daniela, Ghimire, Saroj, Hiergeist, Andreas, Gessner, André, Dickinson, Anne M., Dressel, Ralf, Walter, Lutz
, Stark, Klaus J., Heid, Iris M., Poeck, Hendrik, Edinger, Matthias, Wolff, Daniel, Herr, Wolfgang, Holler, Ernst, Kreutz, Marina and Ghimire, Sakhila
(2022)
Downregulation of the vitamin D receptor expression during acute gastrointestinal graft versus host disease is associated with poor outcome after allogeneic stem cell transplantation.
Frontiers in Immunology 13, p. 1028850.
, Schmidt, Nils-Ole, Merrill, Marsha, Uhl, Martin, Renner, Kathrin, Vollmann-Zwerenz, Arabel, Proescholdt, Martin A. and Hau, Peter
(2022)
Metabolic Heterogeneity of Brain Tumor Cells of Proneural and Mesenchymal Origin.
International Journal of Molecular Sciences 23 (19), p. 11629.
Fulltext not available.
Decking, Sonja-Maria, Bruss, Christina, Babl, Nathalie, Bittner, Sebastian, Klobuch, Sebastian, Thomas, Simone
, Feuerer, Markus, Hoffmann, Petra, Dettmer, Katja
, Oefner, Peter J.
, Renner, Kathrin
and Kreutz, Marina
(2022)
LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid.
International journal of molecular sciences 23 (11), p. 5970.
Hofbauer, Joshua, Hauck, Andreas, Matos, Carina
, Babl, Nathalie, Decking, Sonja-Maria, Rechenmacher, Michael
, Schulz, Christian
, Regotta, Sabine, Mickler, Marion, Haferkamp, Sebastian, Siska, Peter J.
, Herr, Wolfgang, Renner, Kathrin
, Kreutz, Marina
and Schnell, Annette
(2022)
Immunometabolic Markers in a Small Patient Cohort Undergoing Immunotherapy.
Biomolecules 12 (5), p. 716.
Frick, Linus, Hinterland, Linda, Renner, Kathrin
, Vogl, Marion, Babl, Nathalie, Heckscher, Simon, Weigert, Anna, Weiß, Susanne, Gläsner, Joachim, Berger, Raffaela
, Oefner, Peter J.
, Dettmer, Katja
, Kreutz, Marina
, Schatz, Valentin and Jantsch, Jonathan
(2022)
Acidic Microenvironments Found in Cutaneous Leishmania Lesions Curtail NO-Dependent Antiparasitic Macrophage Activity.
Frontiers in Immunology 13, p. 789366.
Matos, Carina
, Renner, Kathrin
, Peuker, Alice, Schoenhammer, Gabriele, Schreiber, Laura, Bruss, Christina, Eder, Ruediger, Bruns, Heiko, Flamann, Cindy, Hoffmann, Petra, Gebhard, Claudia
, Herr, Wolfgang, Rehli, Michael, Peter, Katrin
and Kreutz, Marina
(2022)
Physiological levels of 25‐hydroxyvitamin D₃ induce a suppressive CD4⁺ T cell phenotype not reflected in the epigenetic landscape.
Scandinavian Journal of Immunology.
Matos, Carina
, Peter, Katrin
, Weich, Laura, Peuker, Alice, Schoenhammer, Gabriele, Roider, Tobias
, Ghimire, Sakhila, Babl, Nathalie, Decking, Sonja, Güllstorf, Martina, Kröger, Nicolaus, Hammon, Kathrin, Herr, Wolfgang, Stark, Klaus, Heid, Iris M., Renner, Kathrin
, Holler, Ernst and Kreutz, Marina
(2022)
Anti-Thymocyte Globulin Treatment Augments 1,25-Dihydroxyvitamin D3 Serum Levels in Patients Undergoing Hematopoietic Stem Cell Transplantation.
Frontiers in Immunology 12.
Siska, Peter J.
, Jiao, Jing, Matos, Carina, Singer, Katrin, Berger, Raffaela S.
, Dettmer, Katja
, Oefner, Peter J.
, Cully, Michelle D., Wang, Zhonglin, Quinn III, William J., Oliff, Kristen N., Wilkins, Benjamin J., Christensen, Lanette M., Wang, Liqing, Hancock, Wayne W., Baur, Joseph A., Levine, Matthew H., Ugele, Ines, Mayr, Roman, Renner, Kathrin
, Zhou, Liang, Kreutz, Marina
and Beier, Ulf H.
(2021)
Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo.
EBioMedicine 74, p. 103734.
, Köstler, Josef, Siegmund, Heiko, Ugele, Ines, Paulus, Michael, Dietl, Alexander, Kolodova, Kristina, Steines, Louisa
, Freitag, Katharina, Peuker, Alice, Schönhammer, Gabriele, Raithel, Johanna, Graf, Bernhard, Geismann, Florian, Lubnow, Matthias, Mack, Matthias, Hau, Peter, Bohr, Christopher, Burkhardt, Ralph
, Gessner, André
, Salzberger, Bernd, Wagner, Ralf, Hanses, Frank, Hitzenbichler, Florian, Heudobler, Daniel, Lüke, Florian, Pukrop, Tobias, Herr, Wolfgang, Wolff, Daniel, Spang, Rainer, Poeck, Hendrik, Hoffmann, Petra, Jantsch, Jonathan, Brochhausen, Christoph, Lunz, Dirk, Rehli, Michael, Kreutz, Marina and Renner, Kathrin
(2021)
Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone.
Journal of Clinical Investigation 131 (22), e148225.
Fulltext restricted.
Mack, Matthias
, Renner, Kerstin, Schwittay, Tobias, Chaabane, Sophia, Gottschling, Johanna, Müller, Christine, Tiefenböck, Charlotte, Salewski, Jan-Niklas, Winter, Frederike, Buchtler, Simone, Balam, Saidou
, Malfertheiner, Maximilian Valentin
, Lubnow, Matthias
, Lunz, Dirk, Graf, Bernhard, Hitzenbichler, Florian
, Hanses, Frank, Poeck, Hendrik, Kreutz, Marina
, Orso, Evelyn
, Burkhardt, Ralph
, Niedermair, Tanja, Brochhausen, Christoph
, Gessner, André
and Salzberger, Bernd
(2021)
Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes.
Nature Communications 2021 (12), pp. 1-11.
Renner-Sattler, Kathrin, Fante, Matthias A., Decking, Sonja-Maria, Bruss, Christina, Schreml, Stephan
, Siska, Peter J.
and Kreutz, Marina
(2021)
Heat-Inactivation of Human Serum Destroys C1 Inhibitor, Pro-motes Immune Complex Formation, and Improves Human T Cell Function.
International Journal of Molecular Sciences 22 (5), p. 2646.
Oefner, Peter J.
, Dettmer, Katja
, Berger, Raffaela Sarah, Wachsmuth, Christian J., Waldhier, Magdalena C., Renner-Sattler, Kathrin, Thomas, Simone, Chaturvedi, Anuhar
, Niller, Hans Helmut, Bumes, Elisabeth, Hau, Peter
, Proescholdt, Martin A., Gronwald, Wolfram
, Heuser, Michael and Kreutz, Marina
(2021)
Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite.
Cancers 2021 (13), p. 1756.
, von Toerne, Christine, Werner, Caroline, Shevtsov, Maxim
, Di Genio, Tommaso, Zdralevic, Masa, Pouyssegur, Jacques
, Renner, Kathrin, Kreutz, Marina and Multhoff, Gabriele
(2021)
Targeting Cancer Metabolism Breaks Radioresistance by Impairing the Stress Response.
Cancers 13 (15), p. 3762.
Fulltext not available.
, Ugele, Ines, Nieberle, Felix
, Symeou, Luisa, Schmidhofer, Sandra, Brand, Almut, Meier, Johannes, Spoerl, Steffen, Krupar, Rosemarie, Rümmele, Petra, Siska, Peter
, Renner, Kathrin
, Peter, Katrin, Gerken, Michael, Beckhove, Philipp, Reichert, Torsten E., Kreutz, Marina and Singer, Katrin
(2021)
The predictive power of CD3+ T cell infiltration of oral squamous cell tumors is limited to non-diabetic patients.
Cancer Letters 499, pp. 209-219.
Fulltext not available.
Peter, Katrin
, Siska, Peter J., Roider, Tobias, Matos, Carina, Bruns, Heiko, Renner, Kathrin, Singer, Katrin, Weber, Daniela, Güllstorf, Martina, Kröger, Nicolaus, Wolff, Daniel
, Herr, Wolfgang, Ayuk, Francis, Holler, Ernst, Stark, Klaus, Heid, Iris M. and Kreutz, Marina
(2020)
1,25-dihydroxyvitamin-D3 but not the clinically applied marker 25-hydroxyvitamin-D3 predicts survival after stem cell transplantation.
Bone Marrow Transplantation.
Siska, Peter J.
, Singer, Katrin, Evert, Katja, Renner, Kathrin and Kreutz, Marina
(2020)
The immunological Warburg effect: Can a metabolic‐tumor‐stroma score (MeTS) guide cancer immunotherapy?
Immunological Reviews 295 (1), pp. 187-202.
, O’Sullivan, David, Edwards-Hicks, Joy
, Richter, Gesa, Haring, Eileen, Andrieux, Geoffroy, Halbach, Sebastian, Apostolova, Petya
, Büscher, Jörg, Duquesne, Sandra, Melchinger, Wolfgang, Sauer, Barbara, Shoumariyeh, Khalid, Schmitt-Graeff, Annette, Kreutz, Marina, Lübbert, Michael, Duyster, Justus, Brummer, Tilman
, Boerries, Melanie, Madl, Tobias, Blazar, Bruce R., Groß, Olaf, Pearce, Erika L. and Zeiser, Robert
(2020)
Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans.
Science Translational Medicine 12 (567).
Fulltext not available.
Renner, Kathrin
, Bruss, Christina, Schnell, Annette, Koehl, Gudrun, Becker, Holger M., Fante, Matthias, Menevse, Ayse-Nur, Kauer, Nathalie, Blazquez, Raquel, Hacker, Lisa, Decking, Sonja-Maria, Bohn, Toszka, Faerber, Stephanie, Evert, Katja, Aigle, Lisa, Amslinger, Sabine, Landa, Maria, Krijgsman, Oscar, Rozeman, Elisa A., Brummer, Christina, Siska, Peter J., Singer, Katrin, Pektor, Stefanie, Miederer, Matthias, Peter, Katrin, Gottfried, Eva, Herr, Wolfgang, Marchiq, Ibtisam, Pouyssegur, Jacques, Roush, William R., Ong, SuFey, Warren, Sarah, Pukrop, Tobias
, Beckhove, Philipp
, Lang, Sven A., Bopp, Tobias, Blank, Christian U., Cleveland, John L., Oefner, Peter J., Dettmer, Katja
, Selby, Mark and Kreutz, Marina
(2019)
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
Cell Reports 29 (1), 135-150.e9.
Singer, Katrin, Dettmer, Katja
, Unger, Petra, Schönhammer, Gabriele, Renner, Kathrin
, Peter, Katrin
, Siska, Peter J.
, Berneburg, Mark
, Herr, Wolfgang, Oefner, Peter J.
, Karrer, Sigrid, Kreutz, Marina
and Datz, Elisabeth
(2019)
Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis.
Frontiers in Oncology 2019 (9), p. 605.
Singer, Katrin, Dettmer, Katja
, Unger, Petra, Schoenhammer, Gabriele, Renner, Kathrin, Peter, Katrin, Siska, Peter J., Berneburg, Mark
, Herr, Wolfgang, Oefner, Peter J.
, Karrer, Sigrid, Kreutz, Marina
and Datz, Elisabeth
(2019)
Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis.
Front Oncol 9, p. 605.
Berger, Raffaela S.
, Ellmann, Lisa, Reinders, Joerg, Kreutz, Marina, Stempfl, Thomas, Oefner, Peter J. and Dettmer, Katja
(2019)
Degradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations.
Scientific Reports 9 (1), pp. 1-11.
Ugele, Ines, Cardenas-Conejo, Zugey Elizabeth, Hammon, Kathrin, Wehrstein, Monika, Bruss, Christina, Peter, Katrin, Singer, Katrin, Gottfried, Eva, Boesch, Jakob, Oefner, Peter J., Dettmer, Katja, Renner, Kathrin and Kreutz, Marina
(2019)
D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells.
International Journal of Molecular Sciences 20 (3), p. 742.
Renner, Kathrin, Seilbeck, Anton, Kauer, Nathalie, Ugele, Ines, Siska, Peter J., Brummer, Christina, Bruss, Christina, Decking, Sonja-Maria, Fante, Matthias, Schmidt, Astrid, Hammon, Kathrin, Singer, Katrin, Klobuch, Sebastian, Thomas, Simone
, Gottfried, Eva, Peter, Katrin and Kreutz, Marina
(2018)
Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells.
Frontiers in Pharmacology 9 (1258), pp. 1-13.
, Brand, A., Di Ianni, L., Dettmer, Katja, Reinders, Jörg, Singer, K., Peter, K., Schnell, A., Bruss, C., Decking, S. M., Koehl, G., Felipe-Abrio, B., Durivault, J., Bayer, P., Evangelista, M., O'Brien, T., Oefner, Peter J., Renner, K., Pouyssegur, J. and Kreutz, Marina
(2018)
Double genetic disruption of lactate dehydrogenases A and B is required to ablate the.
J. Biol. Chem. 293 (41), pp. 15947-15961.
Fulltext not available.
Gerthofer, V., Kreutz, Marina, Renner, Kathrin, Jachnik, Birgit, Dettmer, Katja, Oefner, Peter J., Riemenschneider, Markus J., Proescholdt, Martin A., Vollmann-Zwerenz, Arabel, Hau, Peter
and Seliger, Corinna
(2018)
Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma.
Int J Mol Sci 19 (9).
Böttcher, Martin, Renner, Kathrin, Berger, Raffaela
, Mentz, Kristin, Thomas, Simone
, Cardenas-Conejo, Zugey Elizabeth, Dettmer, Katja, Oefner, Peter J., Mackensen, Andreas, Kreutz, Marina and Mougiakakos, Dimitrios
(2018)
D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization.
OncoImmunology 7 (7), e1445454.
, Abendroth, Benjamin, Rothamer, Johanna, Huber, Carina, Büttner-Herold, Maike, Buchele, Vera, Vogler, Tina, Longerich, Thomas, Zundler, Sebastian, Völkl, Simon, Beilhack, Andreas, Rose-John, Stefan, Wirtz, Stefan, Weber, Georg F., Ghimire, Sakhila, Kreutz, Marina, Holler, Ernst, Mackensen, Andreas, Neurath, Markus F. and Hildner, Kai
(2018)
BATF-dependent IL-7RhiGM-CSF+ T cells control intestinal graft-versus-host disease.
Journal of Clinical Investigation 128 (3), pp. 916-930.
Fulltext not available.
Roider, Tobias, Katzfuss, Michael, Matos, Carina, Singer, Katrin, Renner, Kathrin, Oefner, Peter
, Dettmer-Wilde, Katja, Herr, Wolfgang, Holler, Ernst, Kreutz, Marina
and Peter, Katrin
(2016)
Antithymocyte Globulin Induces a Tolerogenic Phenotype in Human Dendritic Cells.
International Journal of Molecular Sciences 17, p. 2081.
, Fichtner-Feigl, S., Kesselring, R., Mack, M., Ritter, U., Schmid, M., Blank, C., Dettmer, Katja
, Oefner, Peter J., Hoffmann, P., Walenta, S., Geissler, E. K., Pouyssegur, J., Villunger, A., Steven, A.
, Seliger, B., Schreml, S., Haferkamp, S., Kohl, E., Karrer, S., Berneburg, Mark, Herr, Wolfgang, Mueller-Klieser, W., Renner, K. and Kreutz, Marina
(2016)
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Cell Metabolism (Cell Metab.) 24 (5), pp. 657-671.
Fulltext not available.
, Ritter, Axel P., Gottfried, E., Peter, Katrin, Dettmer, Katja
, Oefner, Peter J., Bosserhoff, Anja-Katrin and Kreutz, Marina
(2016)
Suppressive effects of tumor cell-derived 5′-deoxy-5′-methylthioadenosine on human T cells.
OncoImmunology 5, e1184802.
Fulltext not available.
Hau, Peter, Leidgens, Verena, Seliger, Corinna, Jachnik, Birgit, Welz, Tobias, Leukel, Petra, Vollmann-Zwerenz, Arabel, Bogdahn, Ulrich, Kreutz, Marina and Grauer, Oliver M.
(2015)
Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms.
PLoS ONE 10 (10), e0140613.
, Herr, Wolfgang and Kreutz, Marina
(2015)
Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions.
Eur J Immunol 45 (9), pp. 2504-2516.
Fulltext not available.
, Singer, Katrin, Renner-Sattler, Kathrin and Kreutz, Marina
(2015)
Lactic acid delays the inflammatory response of human monocytes.
Biochemical and Biophysical Research Communications 457 (3), pp. 412-418.
Fulltext not available.
, Andreesen, Reinhard, Levine, John E.
, Ferrara, James L., Gessner, Andre, Spang, Rainer and Oefner, Peter J.
(2014)
Metagenomic analysis of the stool microbiome in patients receiving allogeneic SCT: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal GvHD.
Biology of Blood and Marrow Transplantation 20 (5), pp. 640-645.
Fulltext not available.
(2014)
Immunologic and metabolic characteristics of HPV-negative and HPV-positive head and neck squamous cell carcinomas are strikingly different.
Virchows Archiv 465 (3), pp. 299-312.
Fulltext not available.
, Gronwald, Wolfram, Bogdahn, Ulrich, Hau, Peter, Kreutz, Marina and Grauer, Oliver M.
(2013)
Diclofenac inhibits lactate formation and efficiently counteracts local immune suppression in a murine glioma model.
International Journal of Cancer 132 (4), pp. 843-853.
Fulltext not available.
, Vogl, Franziska C., Ritter, Axel P., Zhu, Wentao, Nürnberger, Nadine, Kreutz, Marina, Oefner, Peter J.
, Gronwald, Wolfram and Gottfried, Eva
(2013)
Distinct metabolic differences between various human cancer and primary cells.
ELECTROPHORESIS 34 (19), pp. 2836-2847.
Fulltext not available.
Seliger, Corinna, Leukel, Petra, Moeckel, Sylvia, Jachnik, Birgit, Lottaz, Claudio, Kreutz, Marina, Brawanski, Alexander, Proescholdt, Martin, Bogdahn, Ulrich, Bosserhoff, Anja-Katrin
, Vollmann-Zwerenz, Arabel and Hau, Peter
(2013)
Lactate-Modulated Induction of THBS-1 Activates Transforming Growth Factor (TGF)-beta2 and Migration of Glioma Cells In Vitro.
PloS one 8 (11), e78935.
Kreutz, Marina, Gottfried, Eva, Lang, Sven A., Renner, Kathrin, Bosserhoff, Anja-Katrin
, Gronwald, Wolfram, Rehli, Michael
, Einhell, Sabine, Gedig, Isabel, Singer, Katrin, Seilbeck, Anton, Mackensen, Andreas, Grauer, Oliver, Hau, Peter, Dettmer, Katja
, Andreesen, Reinhard and Oefner, Peter
(2013)
New aspects of an old drug: Diclofenac targets MYC and glucose metabolism in tumor cells.
PLoS ONE 8 (7), e66987.
, Landfried, Karin, Koestler, Josef, Huber, Elisabeth, Peter, Katrin, Ammer, Julia, Rogler, Gerhard
, Kreutz, Marina, Spang, Rainer, Hehlgans, Thomas, Edinger, Matthias, Wolff, Daniel, Gessner, Andre and Andreesen, Reinhard
(2012)
Intestinal Microbiota: From Inflammatory Bowel Disease to Bone Marrow Transplantation.
Blood 120 (21), SCI-50-SCI-50.
Fulltext not available.
, Landthaler, Michael, Andreesen, Reinhard, Merad, Miriam and Holler, Ernst
(2012)
Whole-Body UVB Irradiation during Allogeneic Hematopoietic Cell Transplantation Is Safe and Decreases Acute Graft-versus-Host Disease.
Journal of Investigative Dermatology 132 (1), pp. 179-187.
Fulltext not available.
, Peter, Katrin, Kreutz, Marina, Andreesen, Reinhard, Oefner, Peter J.
and Holler, Ernst
(2011)
Tryptophan catabolism is associated with acute GVHD after human allogeneic stem cell transplantation and indicates activation of indoleamine 2,3-dioxygenase.
Blood 118 (26), pp. 6971-6974.
Fulltext not available.
, Gottfried, Eva, Hoves, Sabine
, Kreutz, Marina, Holler, Ernst, Canelas, André B., Kema, Ido and Oefner, Peter J.
(2011)
Quantitative profiling of tryptophan metabolites in serum, urine, and cell culture supernatants by liquid chromatography-tandem mass spectrometry.
Analytical and bioanalytical chemistry 401 (10), pp. 3249-3261.
Fulltext not available.
, Timischl, Birgit, Eberhart, Karin, Dorn, Christoph, Hellerbrand, Claus, Kastenberger, Michael, Kunz-Schughart, Leoni A., Oefner, Peter J.
, Andreesen, Reinhard, Gottfried, Eva and Kreutz, Marina
(2010)
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Journal of immunology 184 (3), pp. 1200-1209.
Fulltext not available.
(2009)
Low doses of 2-deoxy-glucose sensitize acute lymphoblastic leukemia cells to glucocorticoid-induced apoptosis.
Leukemia 23 (11), pp. 2167-2170.
Fulltext not available.
, Stoeltzing, Oliver, Warnecke, Christina, Schölmerich, Jürgen, Oefner, Peter J.
, Kreutz, Marina, Bosserhoff, Anja-Katrin
and Hellerbrand, Claus
(2009)
GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis.
The American journal of pathology 174 (4), pp. 1544-1552.
Fulltext not available.
, Oefner, Peter J.
and Bosserhoff, Anja-Katrin
(2009)
Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma.
Journal of cellular biochemistry 106 (2), pp. 210-219.
Fulltext not available.
, Oefner, Peter J.
, Kastenberger, Michael, Kreutz, Marina, Nickl-Jockschat, Thomas
, Bogdahn, Ulrich, Bosserhoff, Anja-Katrin
and Hau, Peter
(2009)
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.
Neuro-oncology 11 (4), pp. 368-380.
Fulltext not available.
, Gottfried, Eva, Schwarz, Sabine, Rothe, Gregor, Hoves, Sabine
, Renner, Kathrin, Timischl, Birgit, Mackensen, Andreas, Kunz-Schughart, Leoni, Andreesen, Reinhard, Krause, Stefan W.
and Kreutz, Marina
(2007)
Inhibitory effect of tumor cell-derived lactic acid on human T cells.
Blood 109 (9), pp. 3812-9.
Fulltext not available.
, Andreesen, Reinhard, Mackensen, Andreas and Kreutz, Marina
(2006)
Tumor-derived lactic acid modulates dendritic cell activation and antigen expression.
Blood 107 (5), pp. 2013-2021.
Fulltext restricted.
, Hahn, Joachim, Holler, Ernst, Andreesen, Reinhard and Kreutz, Marina
(2006)
Monocyte-derived cells express CYP27A1 and convert vitamin D3 into its active metabolite.
Biochemical and biophysical research communications 349 (1), pp. 209-13.
Fulltext not available.
, Kreutz, Marina, Eisert, Veronika, Dinauer, Norbert, Heinzelmann, Anna, Hallenberger, Sabine, Strayle, Jochen, Walker, Russel, Rübsamen-Waigmann, Helga, Andreesen, Reinhard and von Briesen, Hagen
(2006)
Stimulated trans-acting factor of 50 kDa (Staf50) inhibits HIV-1 replication in human monocyte-derived macrophages.
Virology 356 (1-2), pp. 79-94.
Fulltext not available.
, Thu-Hang, Pham and Kreutz, Marina
(2005)
Epigenetic regulation of the dendritic cell-marker gene ADAM19.
Biochemical and Biophysical Research Communications 332 (2), pp. 456-464.
Fulltext not available.
, Andreesen, Reinhard and Kreutz, Marina
(2003)
Inverse regulation of the ADAM‐family members, decysin and MADDAM/ADAM19 during monocyte differentiation.
Immunology 110 (4), pp. 450-457.
Fulltext not available.
Uphoff, C. C., Hu, Z. B., Gignac, S. M., Ma, W., Rainey, F. A., Kreutz, Marina, Ludwig, W. D. and Drexler, H. G.
(1994)
Characterization of the monocyte-specific esterase (MSE) gene.
Leukemia 8 (9), pp. 1510-1526.
Andreesen, Reinhard and Kreutz, Marina
(1994)
Differentiation of human monocytes in vitro. A model of macrophage ontogeny.
In: Fusenig, N. E. and Graf, H., (eds.)
Cell Culture in Pharmaceutical Research.
Springer, Berlin, pp. 9-27.
ISBN 3540581413; 978-3540581413.
Schlesier, M., Krause, S., Dräger, R., Wolff-Vorbeck, G., Kreutz, Marina, Andreesen, Reinhard and Peter, H. H.
(1994)
Monocyte differentiation and accessory function: different effects on the proliferative responses of an autoreactive T cell clone as compared to alloreactive or antigen-specific T cell lines and primary mixed lymphocyte cultures.
Immunobiology 190 (1-2), pp. 164-174.
Kreutz, Marina, Andreesen, Reinhard, Krause, S. W., Szabo, A., Ritz, E. and Reichel, H.
(1993)
1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages.
Blood 82 (4), pp. 1300-1307.
Krause, S. W., Kreutz, Marina, Zenke, G. and Andreesen, Reinhard
(1992)
Developmental regulation of granulocyte-macrophage colony-stimulating factor production during human monocyte-to-macrophage maturation.
Annals of hematology 64 (4), pp. 190-195.
Kreutz, Marina, Krause, S. W., Hennemann, B., Rehm, A. and Andreesen, Reinhard
(1992)
Macrophage heterogeneity and differentiation: defined serum-free culture conditions induce different types of macrophages in vitro.
Research in immunology 143 (1), pp. 107-115.
Brugger, W., Kreutz, Marina and Andreesen, Reinhard
(1991)
Macrophage colony-stimulating factor is required for human monocyte survival and acts as a cofactor for their terminal differentiation to macrophages in vitro.
Journal of leukocyte biology 49 (5), pp. 483-488.
Kreutz, Marina and Andreesen, Reinhard
(1990)
Induction of human monocyte to macrophage maturation in vitro by 1,25-dihydroxyvitamin D3.
Blood 76 (12), pp. 2457-2461.
Andreesen, Reinhard, Brugger, W., Scheibenbogen, C., Kreutz, Marina, Leser, H. G., Rehm, A. and Löhr, G. W.
(1990)
Surface phenotype analysis of human monocyte to macrophage maturation.
Journal of leukocyte biology 47 (6), pp. 490-497.
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