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Number of items: 127.

2020

Schoen, Marian, Simeth, Jakob, Heinrich, Paul, Goertler, F., Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J. , Altenbuchinger, Michael and Spang, Rainer (2020) DTD: An R Package for Digital Tissue Deconvolution. J. Comput. Biol.. Fulltext not available.

Goertler, Franziska, Schoen, Marian, Simeth, Jakob, Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J. , Spang, Rainer and Altenbuchinger, Michael (2020) Loss-Function Learning for Digital Tissue Deconvolution. J. Comput. Biol.. Fulltext not available.

Schill, Rudolf, Solbrig, Stefan, Wettig, Tilo and Spang, Rainer (2020) Modelling cancer progression using Mutual Hazard Networks. Bioinformatics 36 (1), pp. 241-249. Fulltext not available.

2019

Arlt, A., von Bonin, F., Rehberg, Thorsten, Perez-Rubio, Paula, Engelmann, Julia C. , Limm, Katharina, Reinke, S., Dullin, C., Sun, Xueni, Specht, R., Maulhardt, M., Linke, F., Bunt, G., Klapper, W., Vockerodt, M., Wilting, J., Pukrop, T., Dettmer, Katja , Gronwald, Wolfram , Oefner, Peter J. , Spang, Rainer and Kube, D. (2019) High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination. Mol Oncol. Fulltext not available.

Altenbuchinger, Michael, Zacharias, Helena , Solbrig, S., Schaefer, Andreas, Buyukozkan, M., Schultheiss, U. T., Kotsis, F., Kottgen, A., Spang, Rainer, Oefner, Peter J. , Krumsiek, J. and Gronwald, Wolfram (2019) A multi-source data integration approach reveals novel associations between metabolites and renal outcomes in the German Chronic Kidney Disease study. Sci Rep 9 (1), p. 13954.

Staiger, A. M., Altenbuchinger, Michael, Ziepert, M., Kohler, Christian , Horn, H., Huttner, Michael, Huttl, K. S., Glehr, Gunther, Klapper, W., Szczepanowski, M., Richter, J., Stein, H., Feller, A. C., Moller, P., Hansmann, M. L., Poeschel, V., Held, G., Loeffler, M., Schmitz, N., Trumper, L., Pukrop, T., Rosenwald, A., Ott, G., Spang, Rainer, Emed Demonstrator Project, and German High Grade Non-Hodgkin’s Lymphoma Study Group (DSHNHL), (2019) A novel lymphoma-associated macrophage interaction signature (LAMIS) provides robust risk prognostication in diffuse large B-cell lymphoma clinical trial cohorts of the DSHNHL. Leukemia. Fulltext not available.

Wagner, M., Hansel, R., Reinke, S., Richter, J., Altenbuchinger, Michael, Braumann, U. D., Spang, Rainer, Loffler, M. and Klapper, W. (2019) Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach. Biol Proced Online 21, p. 13.

Itzel, T., Spang, Rainer, Maass, T., Munker, S., Roessler, S., Ebert, M. P., Schlitt, Hans J. , Herr, Wolfgang, Evert, Matthias and Teufel, A. (2019) Random gene sets in predicting survival of patients with hepatocellular carcinoma. J. Mol. Med.. Fulltext not available.

Kleo, K., Dimitrova, L., Oker, E., Tomaszewski, N., Berg, E., Taruttis, Franziska, Engelmann, Julia C. , Schwarzfischer, Philipp, Reinders, Jörg , Spang, Rainer, Gronwald, Wolfram , Oefner, Peter J. and Hummel, Michael (2019) Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma. BMC Cancer 19 (1), p. 322.

Zacharias, Helena, Altenbuchinger, Michael, Schultheiss, U. T., Samol, Claudia, Kotsis, F., Poguntke, I., Sekula, P., Krumsiek, J., Kottgen, A., Spang, Rainer, Oefner, Peter J. and Gronwald, Wolfram (2019) A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease. Journal of Proteome Research. Fulltext not available.

Schnitter, A., Kohler, Christian , Reddemann, K., Reinke, S., Thorns, C., Fend, F., Federmann, B., Moeller, P., Szczepanowski, Monika, Spang, Rainer and Klapper, Wolfram (2019) Therapeutic targets and microenvironment in sequential biopsies of classical Hodgkin lymphoma at diagnosis and relapse. Journal of Hematopathology 12 (1), pp. 11-17.

Ziegler, Christian, Graf, Johannes, Faderl, Stefan, Schedlbauer, Jessica, Strieder, Nicholas, Förstl, Bianca, Spang, Rainer, Bruckmann, Astrid, Merkl, Rainer , Hombach, Sonja and Kretz, Markus (2019) The long non-coding RNA LINC00941 and SPRR5 are novel regulators of human epidermal homeostasis. EMBO Rep., e46612. Fulltext not available.

2018

Heinrich, Paul, Kohler, Christian , Ellmann, Lisa, Kuerner, Paul, Spang, Rainer, Oefner, Peter J. and Dettmer, Katja (2018) Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR. Scientific Reports 8 (17910), pp. 1-10.

Fröhlich, Holger , Balling, R., Beerenwinkel, N., Kohlbacher, O., Kumar, S., Lengauer, T., Maathuis, M. H., Moreau, Y., Murphy, S. A., Przytycka, T. M., Rebhan, M., Rost, H., Schuppert, A., Schwab, M., Spang, Rainer, Stekhoven, D., Sun, J., Weber, A., Ziemek, D. and Zupan, B. (2018) From hype to reality: data science enabling personalized medicine. BMC Med 16 (1), p. 150.

Cho, H., Berger, B., Peng, J., Galitzine, C., Vitek, O., Beltran, P. M. J., Cristea, I. M., Gortler, F., Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J. , Spang, Rainer, Altenbuchinger, Michael, Basso, R. S., Hochbaum, D., Vandin, F., Silverbush, D., Cristea, S., Yanovich, G., Geiger, T., Beerenwinkel, N., Sharan, R., Zhou, Z., Luhmann, N., Alikhan, N. F. and Achtman, M. (2018) Principles of Systems Biology, No. 31. Cell Syst 7 (2), pp. 133-135. Fulltext not available.

Riquelme, Paloma , Haarer, Jan, Kammler, Anja, Walter, Lisa , Tomiuk, Stefan, Ahrens, Norbert , Wege, Anja K. , Goecze, Ivan, Zecher, Daniel, Banas, Bernhard , Spang, Rainer, Fändrich, Fred, Lutz, Manfred B., Sawitzki, Birgit, Schlitt, Hans J. , Ochando, Jordi , Geissler, Edward K. and Hutchinson, James A. (2018) TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity. Nature Communications 9 (2858), pp. 1-18.

Riquelme, Paloma , Haarer, Jan, Kammler, Anja Nadine, Walter, Lisa , Tomiuk, S., Ahrens, Norbert , Wege, Anja K. , Goecze, Ivan, Zecher, D., Banas, Bernhard , Spang, Rainer, Fandrich, F., Lutz, M. B., Sawitzki, B., Schlitt, Hans-Jürgen , Ochando, Jordi , Geissler, Edward K. and Hutchinson, J. A. (2018) TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity. Nat Commun 9, p. 2858.

Reinke, Sarah , Richter, Julia, Fend, Falko, Feller, Alfred, Hansmann, Martin-Leo, Hüttl, Katrin, Oschlies, Ilske, Ott, German, Möller, Peter, Rosenwald, Andreas, Stein, Harald, Altenbuchinger, Michael, Spang, Rainer and Klapper, Wolfram (2018) Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma—a feasibility study using full slide staining. Virchows Archiv. Fulltext not available.

Görtler, Franziska, Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J. , Spang, Rainer and Altenbuchinger, Michael (2018) Loss-function learning for digital tissue deconvolution. In: Raphael, Benjamin J., (ed.) Research in Computational Molecular Biology : 22nd Annual International Conference, RECOMB 2018, Paris, France, April 21-24, 2018, Proceedings. Lecture Notes in Computer Science, 10812. Springer International Publishing, Cham, pp. 75-89. ISBN 978-3-319-89929-9 ; 978-3-319-89928-2. Fulltext not available.

Feist, M., Schwarzfischer, Philipp, Heinrich, Paul, Sun, Xueni, Kemper, J., von Bonin, F., Perez-Rubio, Paula, Taruttis, Franziska, Rehberg, Thorsten, Dettmer, Katja , Gronwald, Wolfram , Reinders, Jörg , Engelmann, Julia C. , Dudek, J., Klapper, W., Trumper, L., Spang, Rainer, Oefner, Peter J. and Kube, D. (2018) Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression. Nat Commun 9 (1), p. 1514.

Horn, H., Kohler, Christian, Witzig, R., Kreuz, M., Leich, E., Klapper, W., Hummel, M., Loeffler, M., Trumper, L., Spang, Rainer, Rosenwald, A. and Ott, G. (2018) Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2. Haematologica. Fulltext not available.

Schill, Rudolf, Solbrig, Stefan, Wettig, Tilo and Spang, Rainer (2018) Modelling cancer progression using Mutual Hazard Networks. biorxiv.org. (Submitted)

2017

Paul, U., Richter, J., Stuhlmann-Laiesz, C., Kreuz, M., Nagel, I., Horn, H., Staiger, A. M., Aukema, S. M., Hummel, M., Ott, G., Spang, Rainer, Rosenwald, A., Feller, A. C., Cogliatti, S., Stein, H., Hansmann, M. L., Moller, P., Szczepanowski, M., Burkhardt, B., Pfreundschuh, M., Schmitz, N., Loeffler, M., Trumper, L., Siebert, R. and Klapper, W. (2017) Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC. Leuk. Lymphoma, pp. 1-9. Fulltext not available.

Zacharias, Helena, Rehberg, Thorsten, Mehrl, S., Richtmann, D., Wettig, Tilo, Oefner, Peter J., Spang, Rainer, Gronwald, Wolfram and Altenbuchinger, Michael (2017) Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints. J. Proteome Res.. Fulltext not available.

Altenbuchinger, Michael, Schwarzfischer, Philipp, Rehberg, Thorsten, Reinders, Jörg , Kohler, Christian , Gronwald, Wolfram , Richter, J., Szczepanowski, M., Masqué-Soler, N., Klapper, W., Oefner, Peter J. and Spang, Rainer (2017) Molecular signatures that can be transferred across different omics platforms. Bioinformatics 33 (14), i333-i340. Fulltext not available.

Oschlies, I., Kohler, Christian, Szczepanowski, Monika, Koch, K., Gontarewicz, A., Metze, D., Hillen, U., Richter, J., Spang, Rainer and Klapper, W. (2017) Spindle-cell variant of primary cutaneous follicle center B-cell lymphomas are germinal center B-cell lymphomas by gene expression profiling using formalin-fixed paraffin embedded specimen. J Invest Dermatol. Fulltext not available.

Szczepanowski, M., Lange, J., Kohler, Christian, Masque-Soler, N., Zimmermann, M., Aukema, S. M., Altenbuchinger, Michael, Rehberg, Thorsten, Mahn, F., Siebert, R., Spang, Rainer, Burkhardt, B. and Klapper, W. (2017) Cell-of-origin classification by gene expression and MYC-rearrangements in diffuse large B-cell lymphoma of children and adolescents. Br. J. Haematol.. Fulltext not available.

Rohde, M., Bonn, B. R., Zimmermann, M., Lange, J., Moricke, A., Klapper, W., Oschlies, I., Szczepanowski, M., Nagel, I., Schrappe, M., Loeffler, M., Siebert, R., Reiter, A., Burkhardt, B., Altenbuchinger, Michael, Dettmer-Wilde, Katja, Engelmann, Julia C. , Gronwald, Wolfram , Oefner, Peter J. , Schwarzfischer, Philipp, Taruttis, Franziska and Spang, Rainer (2017) Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt-Münster protocols. Haematologica 102 (6), pp. 1091-1098. Fulltext not available.

Feist, M., Kemper, J., Taruttis, Franziska, Rehberg, Thorsten, Engelmann, Julia C. , Gronwald, Wolfram, Hummel, Michael, Spang, Rainer and Kube, Dieter (2017) Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis. International Journal of Cancer: Int. J. Cancer. Fulltext not available.

Schwarzfischer, Philipp, Reinders, Jörg, Dettmer, Katja , Kleo, K., Dimitrova, L., Hummel, M., Feist, M., Kube, D., Szczepanowski, M., Klapper, W., Taruttis, Franziska, Engelmann, Julia C. , Spang, Rainer, Gronwald, Wolfram and Oefner, Peter J. (2017) Comprehensive metaboproteomics of Burkitt's and diffuse large B-cell lymphoma cell lines and primary tumor tissues reveals distinct differences in pyruvate content and metabolism. Journal of Proteome Research 16, pp. 1105-1120. Fulltext not available.

Taruttis, Franziska, Feist, M., Schwarzfischer, Philipp, Gronwald, Wolfram, Kube, D., Spang, Rainer and Engelmann, Julia C. (2017) External calibration with Drosophila whole-cell spike-ins delivers absolute mRNA fold changes from human RNA-Seq and qPCR data. BioTechniques 62 (2), pp. 53-61. Fulltext not available.

Lottaz, Claudio, Gronwald, Wolfram , Spang, Rainer and Engelmann, Julia C. (2017) High-Dimensional Profiling for Computational Diagnosis. In: Bioinformatics : Volume II: Structure, Function, and Applications. Methods in Molecular Biology, 1526. Springer, New York, pp. 205-229. ISBN 978-1-4939-6611-0. Fulltext not available.

2016

Hosseini, H., Obradovic, M. M., Hoffmann, M., Harper, K. L., Sosa, M. S., Werner-Klein, M., Nanduri, L. K., Werno, C., Ehrl, C., Maneck, M., Patwary, N., Haunschild, G., Guzvic, M., Reimelt, C., Grauvogl, Michael, Eichner, N., Weber, F., Hartkopf, A. D., Taran, F. A., Brucker, S. Y., Fehm, T., Rack, B., Buchholz, S., Spang, Rainer, Meister, Gunter, Aguirre-Ghiso, J. A. and Klein, Christoph A. (2016) Early dissemination seeds metastasis in breast cancer. Nature 540, pp. 552-558. Fulltext not available.

Altenbuchinger, Michael, Rehberg, Thorsten, Zacharias, Helena, Stämmler, Frank, Dettmer, Katja , Weber, Daniela, Hiergeist, Andreas, Gessner, Andre, Holler, Ernst, Oefner, Peter J. and Spang, Rainer (2016) Reference point insensitive molecular data analysis. Bioinformatics.

Stämmler, Frank, Glasner, J., Hiergeist, Andreas , Holler, Ernst, Weber, Daniela, Oefner, Peter J. , Gessner, Andre and Spang, Rainer (2016) Adjusting microbiome profiles for differences in microbial load by spike-in bacteria. Microbiome 4 (1), p. 28.

Moffa, Giusi, Erdmann, Gerrit, Voloshanenko, Oksana, Hundsrucker, Christian, Sadeh, Mohammad Javad, Boutros, Michael and Spang, Rainer (2016) Refining Pathways: A Model Comparison Approach. PLoS One 11 (6), e0155999.

Teufel, Andreas, Itzel, Timo, Erhart, W., Brosch, M., Wang, X. Y., Kim, Y. O., von Schonfels, W., Herrmann, A., Bruckner, S., Stickel, F., Dufour, J. F., Chavakis, T., Hellerbrand, Claus, Spang, Rainer, Maass, Thorsten, Becker, T., Schreiber, S., Schafmayer, C., Schuppan, D. and Hampe, J. (2016) Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues from Patients. Gastroenterology. Fulltext not available.

Schrader, A., Meyer, Katharina, Walther, N., Stolz, A., Feist, M., Hand, E., Bonin, F. von, Evers, Maurits, Kohler, Christian, Shirneshan, K., Vockerodt, M., Klapper, W., Szczepanowski, M., Murray, P. G., Bastians, H., Trümper, Lorenz, Spang, Rainer and Kube, Dieter (2016) Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data. OncoTarget.

Moeckel, Sylvia, Vollmann-Zwerenz, Arabel, Proescholdt, Martin A., Brawanski, Alexander, Riemenschneider, Markus J., Bogdahn, Ulrich, Bosserhoff, A. K., Spang, Rainer and Hau, Peter (2016) Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro. PLoS ONE 11 (3), e0151312.

2015

Pirkl, Martin, Hand, E., Kube, D. and Spang, Rainer (2015) Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models. Bioinformatics.

Hochrein, Jochen, Zacharias, Helena, Taruttis, Franziska, Samol, Claudia, Engelmann, Julia C., Spang, Rainer, Oefner, Peter J. and Gronwald, Wolfram (2015) Data Normalization of (1)H NMR Metabolite Fingerprinting Data Sets in the Presence of Unbalanced Metabolite Regulation. J. Proteome Res. 14 (8), pp. 3217-3228. Fulltext not available.

Taruttis, Franziska, Spang, Rainer and Engelmann, Julia C. (2015) A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA). Bioinformatics 31, p. 22.

Masqué-Soler, Neus, Szczepanowski, Monika, Kohler, Christian W., Aukema, Sietse M., Nagel, Inga, Richter, Julia, Siebert, Reiner, Spang, Rainer, Burkhardt, Birgit and Klapper, Wolfram (2015) Clinical and pathological features of Burkitt lymphoma showing expression of BCL2 - an analysis including gene expression in formalin-fixed paraffin-embedded tissue. British Journal of Haematology = Br J Haematol 171, pp. 501-508.

Engelmann, Julia C., Amann, Thomas, Ott-Rötzer, Brigitta, Nützel, Magit, Reinders, Yvonne, Reinders, Jörg, Thasler, Wolfgang E., Kristl, Theresa, Teufel, Andreas, Huber, Christian G., Oefner, Peter J., Spang, Rainer and Hellerbrand, Claus (2015) Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma. PLoS Computational Biology 11 (5), pp. 1-22.

Weber, Daniela, Oefner, Peter J., Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Hahn, Joachim, Wolff, Daniel, Stämmler, Frank, Spang, Rainer, Herr, Wolfgang, Dettmer, Katja and Holler, Ernst (2015) Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome. Blood 126 (14), pp. 1723-1728.

2014

Hau, Peter, Moeckel, Sylvia, Meyer, Katharina, Leukel, Petra, Heudorfer, Fabian, Seliger, Corinna, Stangl, Christina, Bogdahn, Ulrich, Proescholdt, Martin A., Brawanski, Alexander, Vollmann-Zwerenz, Arabel, Riemenschneider, Markus J., Bosserhoff, Anja-Katrin and Spang, Rainer (2014) Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro. PLoS ONE 9 (9), e108632.

Hannus, Michael, Beitzinger, Michaela, Engelmann, Julia C., Weickert, Marie-Theresa, Spang, Rainer, Hannus, Stefan and Meister, Gunter (2014) siPools: highly complex but accurately defined siRNA pools eliminate off-target effects. Nucleic Acids Research 42, pp. 8049-8061.

Holler, Ernst, Butzhammer, Peter, Schmid, Karin, Hundsrucker, Christian, Koestler, Josef, Peter, Katrin, Zhu, Wentao, Sporrer, Daniela, Hehlgans, Thomas, Kreutz, Marina, Holler, Barbara, Wolff, Daniel, Edinger, Matthias, Andreesen, Reinhard, Levine, John E., Ferrara, James L, Gessner, Andre, Spang, Rainer and Oefner, Peter J. (2014) Metagenomic analysis of the stool microbiome in patients receiving allogeneic SCT: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal GvHD. Biology of Blood and Marrow Transplantation 20 (5), pp. 640-645. Fulltext not available.

Dorn, Christoph, Engelmann, Julia C., Saugspier, Michael Sebastian, Koch, Andreas, Hartmann, Arndt, Spang, Rainer, Bosserhoff, Anja Katrin and Hellerbrand, Claus (2014) Increased expression of c-Jun in nonalcoholic fatty liver disease. Laboratory Investigation 94, pp. 394-408. Fulltext not available.

Dümcke, Sebastian, Bräuer, Johannes, Anchang, Benedict Nchang, Spang, Rainer, Beerenwinkel, Niko and Tresch, Achim (2014) Exact likelihood computation in Boolean networks with probabilistic time delays, and its application in signal network reconstruction. Bioinformatics 30 (3), pp. 414-419.

Salaverria, Itziar, Martin-Guerrero, Idoia, Wagener, Rabea, Kreuz, Markus, Kohler, Christian, Richter, Julia, Pienkowska-Grela, Barbara, Adam, Patrick, Burkhardt, Birgit, Claviez, Alexander, Damm-Welk, Christine, Drexler, H. G., Hummel, Michael, Jaffe, Elaine S., Kueppers, Ralf, Lefebvre, Christine, Lisfeld, Jasmin, Loeffler, Markus, Mcleod, Roderick A., Nagel, Inga, Oschlies, Ilske, Rosolowski, Maciej, Russell, Robert B., Rymkiewicz, Grzegorz, Schindler, Detlev, Schlesner, Matthias, Scholtysik, Rene, Schwaenen, Carsten, Spang, Rainer, Szczepanowski, Monika, Truemper, Lorenz, Vater, Inga, Wessendorf, Swen, Klapper, Wolfram and Siebert, Rainer (2014) A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma. Blood 123, pp. 1187-1198. Fulltext not available.

Dorn, Christoph , Engelmann, Julia C, Saugspier, Michael, Koch, Andreas, Hartmann, Arndt, Müller, Martina, Spang, Rainer, Bosserhoff, Anja and Hellerbrand, Claus (2014) Increased expression of c-Jun in nonalcoholic fatty liver disease. Laboratory Investigation 94 (4), pp. 394-408. Fulltext not available.

2013

Schmid, Rainer, Meyer, Katharina, Spang, Rainer, Schittek, Birgit and Bosserhoff, Anja-Katrin (2013) YBX1 is a modulator of MIA/CD-RAP-dependent chondrogenesis. PLoS ONE 8 (12).

Sadeh, Mohammad Javad, Moffa, Giusi and Spang, Rainer (2013) Considering unknown unknowns: reconstruction of nonconfoundable causal relations in biological networks. Journal of computational biology 20 (11), pp. 920-932. Fulltext not available.

Burghardt, Tillmann, Kastner, Jürgen, Suleiman, Hani, Rivera-Milla, Eric, Stepanova, Natalya, Lottaz, Claudio, Kubitza, Marion, Böger, Carsten A., Schmidt, Sarah, Gorski, Mathias, de Vries, Uwe, Schmidt, Helga, Hertting, Irmgard, Kopp, Jeffrey, Rascle, Anne, Moser, Markus, Heid, Iris M., Warth, Richard, Spang, Rainer, Wegener, Joachim, Mierke, Claudia T., Englert, Christoph and Witzgall, Ralph (2013) LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys. Journal of the American Society of Nephrology : JASN 24 (11), pp. 1830-1848. Fulltext not available.

Voloshanenko, Oksana, Erdmann, Gerrit, Dubash, Taronish D, Augustin, Iris, Metzig, Marie, Moffa, Giusi, Hundsrucker, Christian, Kerr, Grainne, Sandmann, Thomas, Anchang, Benedikt, Demir, Kubilay, Boehm, Christina, Leible, Svenja, Ball, Claudia R, Glimm, Hanno, Spang, Rainer and Boutros, Michael (2013) Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells. Nature communications 4, p. 2610.

Masqué-Soler, Neus, Szczepanowski, Monika, Kohler, Christian, Spang, Rainer and Klapper, Wolfram (2013) Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens. Blood 122 (11), pp. 1985-1986.

Schmid, Rainer, Meyer, Katharina, Spang, Rainer, Schittek, Birgit and Bosserhoff, Anja-Katrin (2013) Melanoma inhibitory activity promotes melanoma development through activation of YBX1. Pigment cell & melanoma research 26 (5), pp. 685-696. Fulltext not available.

Walther, Neele, Ulrich, Antje, Vockerodt, Martina, von Bonin, Frederike, Klapper, Wolfram, Meyer, Katharina, Eberth, Sonja, Pukrop, Tobias, Spang, Rainer, Trümper, Lorenz and Kube, Dieter (2013) Aberrant lymphocyte enhancer-binding factor 1 expression is characteristic for sporadic Burkitt's lymphoma. The American journal of pathology 182 (4), pp. 1092-1098. Fulltext not available.

Kelly, Gemma L, Stylianou, Julianna, Rasaiyaah, Jane, Wei, Wenbin, Thomas, Wendy, Croom-Carter, Deborah, Kohler, Christian, Spang, Rainer, Woodman, Ciaran, Kellam, Paul, Rickinson, Alan N. and Bell, Andrew I. (2013) Different patterns of Epstein-Barr virus latency in endemic Burkitt lymphoma (BL) lead to distinct variants within the BL-associated gene expression signature. Journal of virology 87 (5), pp. 2882-2894.

Aukema, Sietse M, Kreuz, Markus, Kohler, Christian, Rosolowski, Maciej, Hasenclever, Dirk, Hummel, Michael, Küppers, Ralf, Lenze, Dido, Ott, German, Pott, Christiane, Richter, Julia, Rosenwald, Andreas, Szczepanowski, Monika, Schwaenen, Carsten, Stein, Harald, Trautmann, Heiko, Wessendorf, Swen, Trümper, Lorenz, Loeffler, Markus, Spang, Rainer, Kluin, Philip M, Klapper, Wolfram and Siebert, Reiner (2013) Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma. Haematologica 99 (4), pp. 726-735.

Schif, Birgit, Lennerz, Jochen K., Kohler, Christian, Bentink, Stefan, Kreuz, Markus, Melzner, Ingo, Ritz, Olga, Trümper, Lorenz, Loeffler, Markus, Spang, Rainer and Möller, Peter (2013) SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients. Oncotarget 4 (1), pp. 35-47.

2012

Hochrein, Jochen, Klein, Matthias S., Zacharias, Helena, Li, Juan, Wijffels, Gene, Schirra, Horst Joachim, Spang, Rainer, Oefner, Peter J. and Gronwald, Wolfram (2012) Performance evaluation of algorithms for the classification of metabolic 1H NMR fingerprints. Journal of proteome research 11 (12), pp. 6242-6251. Fulltext not available.

Richter, Julia, Schlesner, Matthias, Hoffmann, Steve, Kreuz, Markus, Leich, Ellen, Burkhardt, Birgit, Rosolowski, Maciej, Ammerpohl, Ole, Wagener, Rabea, Bernhart, Stephan H., Lenze, Dido, Szczepanowski, Monika, Paulsen, Maren, Lipinski, Simone, Russell, Robert B., Adam-Klages, Sabine, Apic, Gordana, Claviez, Alexander, Hasenclever, Dirk, Hovestadt, Volker, Hornig, Nadine, Korbel, Jan O, Kube, Dieter, Langenberger, David, Lawerenz, Chris, Lisfeld, Jasmin, Meyer, Katharina, Picelli, Simone, Pischimarov, Jordan, Radlwimmer, Bernhard, Rausch, Tobias, Rohde, Marius, Schilhabel, Markus, Scholtysik, René, Spang, Rainer, Trautmann, Heiko, Zenz, Thorsten, Borkhardt, Arndt, Drexler, Hans G., Möller, Peter, MacLeod, Roderick A. F., Pott, Christiane, Schreiber, Stefan, Trümper, Lorenz, Loeffler, Markus, Stadler, Peter F., Lichter, Peter, Eils, Roland, Küppers, Ralf, Hummel, Michael, Klapper, Wolfram, Rosenstiel, Philip, Rosenwald, Andreas, Brors, Benedikt and Siebert, Reiner (2012) Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. Nature genetics 44 (12), pp. 1316-1320. Fulltext not available.

Beier, Christoph P., Kumar, Praveen, Meyer, Katharina, Leukel, Petra, Bruttel, Valentin, Aschenbrenner, Ines, Riemenschneider, Markus J., Fragoulis, Athanassios, Rümmele, Petra, Lamszus, Katrin, Schulz, Jörg B., Weis, Joachim, Bogdahn, Ulrich, Wischhusen, Jörg, Hau, Peter, Spang, Rainer and Beier, Dagmar (2012) The cancer stem cell subtype determines immune infiltration of glioblastoma. Stem Cells and Development 21 (15), pp. 2753-2761. Fulltext not available.

Schrader, Alexandra, Bentink, Stefan, Spang, Rainer, Lenze, Dido, Hummel, Michael, Kuo, Michael, Arrand, John R, Murray, Paul G, Trümper, Lorenz, Kube, Dieter and Vockerodt, Martina (2012) High Myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas. International journal of cancer 131 (4), E348-E361. Fulltext not available.

Odoardi, Francesca, Sie, Christopher, Streyl, Kristina, Ulaganathan, Vijay K, Schläger, Christian, Lodygin, Dmitri, Heckelsmiller, Klaus, Nietfeld, Wilfried, Ellwart, Joachim, Klinkert, Wolfgang E F, Lottaz, Claudio, Nosov, Mikhail, Brinkmann, Volker, Spang, Rainer, Lehrach, Hans, Vingron, Martin, Wekerle, Hartmut, Flügel-Koch, Cassandra and Flügel, Alexander (2012) T cells become licensed in the lung to enter the central nervous system. Nature 488 (7413), pp. 675-679. Fulltext not available.

Hertwig, Falk, Meyer, Katharina, Braun, Sebastian, Ek, Sara, Spang, Rainer, Pfenninger, Cosima V., Artner, Isabella, Prost, Gaëlle, Chen, Xinbin, Biegel, Jaclyn A., Judkins, Alexander R., Englund, Elisabet and Nuber, Ulrike A. (2012) Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells. Cancer research 72 (13), pp. 3381-3392. Fulltext not available.

Kohl, Stefanie M., Klein, Matthias S., Hochrein, Jochen, Oefner, Peter J., Spang, Rainer and Gronwald, Wolfram (2012) State-of-the art data normalization methods improve NMR-based metabolomic analysis. Metabolomics 8 (Suppl), pp. 146-160. Fulltext not available.

Klapper, Wolfram, Kreuz, Markus, Kohler, Christian, Burkhardt, Birgit, Szczepanowski, Monika, Salaverria, Itziar, Hummel, Michael, Loeffler, Markus, Pellissery, Shoji, Woessmann, Wilhelm, Schwänen, Carsten, Trümper, Lorenz, Wessendorf, Swen, Spang, Rainer, Hasenclever, Dirk and Siebert, Reiner (2012) Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma. Blood 119 (8), pp. 1882-1887. Fulltext not available.

Engelmann, Julia C. and Spang, Rainer (2012) A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions. PloS ONE 7 (7), e40634.

2011

Appel, Inka, Gronwald, Wolfram and Spang, Rainer (2011) Estimating classification probabilities in high-dimensional diagnostic studies. Bioinformatics 27 (18), pp. 2563-2570. Fulltext not available.

Maneck, Matthias, Schrader, Alexandra, Kube, Dieter and Spang, Rainer (2011) Genomic data integration using guided clustering. Bioinformatics 27 (16), pp. 2231-2238. Fulltext not available.

Salaverria, Itziar, Philipp, Claudia, Oschlies, Ilske, Kohler, Christian, Kreuz, Markus, Szczepanowski, Monika, Burkhardt, Birgit, Trautmann, Heiko, Gesk, Stefan, Andrusiewicz, Miroslaw, Berger, Hilmar, Fey, Miriam, Harder, Lana, Hasenclever, Dirk, Hummel, Michael, Loeffler, Markus, Mahn, Friederike, Martin-Guerrero, Idoia, Pellissery, Shoji, Pott, Christiane, Pfreundschuh, Michael, Reiter, Alfred, Richter, Julia, Rosolowski, Maciej, Schwaenen, Carsten, Stein, Harald, Trümper, Lorenz, Wessendorf, Swen, Spang, Rainer, Küppers, Ralf, Klapper, Wolfram and Siebert, Reiner (2011) Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults. Blood 118 (1), pp. 139-147. Fulltext not available.

VerMilyea, Matthew, Maneck, Matthias, Yoshida, Naoko, Blochberger, Isabell, Suzuki, Emi, Suzuki, Toru, Spang, Rainer, Klein, Christoph A. and Perry, Anthony C. F. (2011) Transcriptome asymmetry within mouse zygotes but not between early embryonic sister blastomeres. The EMBO journal 30 (9), pp. 1841-1851. Fulltext not available.

Seitz, Volkhard, Butzhammer, Peter, Hirsch, Burkhard, Hecht, Jochen, Gütgemann, Ines, Ehlers, Anke, Lenze, Dido, Oker, Elisabeth, Sommerfeld, Anke, von der Wall, Edda, König, Christoph, Zinser, Christian, Spang, Rainer and Hummel, Michael (2011) Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma. PLoS One 6 (11), e26837.

2010

Scholtysik, René, Kreuz, Markus, Klapper, Wolfram, Burkhardt, Birgit, Feller, Alfred, Hummel, Michael, Loeffler, Markus, Rosolowski, Maciej, Schwaenen, Carsten, Spang, Rainer, Stein, Harald, Thorns, Christoph, Trümper, Lorenz, Vater, Inga, Wessendorf, Swen, Zenz, Thorsten, Siebert, Reiner and Küppers, Ralf (2010) Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis. Haematologica 95 (12), pp. 2047-2055.

Lottaz, Claudio, Beier, Dagmar, Meyer, Katharina, Kumar, Praveen, Hermann, Andreas, Schwarz, Johannes, Junker, Markus, Oefner, Peter J., Bogdahn, Ulrich, Wischhusen, J, Spang, Rainer, Storch, Alexander and Beier, Christoph P. (2010) Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin. Cancer research 70 (5), pp. 2030-2040. Fulltext not available.

2009

Thieme, Marian, Lottaz, Claudio, Niederstätter, Harald, Parson, Walther, Spang, Rainer and Oefner, Peter J. (2009) ReseqChip: automated integration of multiple local context probe data from the MitoChip array in mitochondrial DNA sequence assembly. BMC bioinformatics 10, p. 440.

Almstetter, Martin F., Appel, Inka, Gruber, Michael, Lottaz, Claudio, Timischl, Birgit, Spang, Rainer, Dettmer, Katja and Oefner, Peter J. (2009) Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Analytical chemistry 81 (14), pp. 5731-5739. Fulltext not available.

Vlad, Marcel O., Corlan, Alexandru D., Morán, Federico, Spang, Rainer, Oefner, Peter J. and Ross, John (2009) Kinetic laws, phase-phase expansions, renormalization group, and INR calibration. Proceedings of the National Academy of Sciences of the United States of America 106 (16), pp. 6465-6470. Fulltext not available.

Anchang, Benedict Nchang, Sadeh, Mohammad Javad, Jacob, Juby, Tresch, Achim, Vlad, Marcel O., Oefner, Peter J. and Spang, Rainer (2009) Modeling the temporal interplay of molecular signaling and gene expression by using dynamic nested effects models. Proceedings of the National Academy of Sciences of the United States of America 106 (16), pp. 6447-6452. Fulltext not available.

Martín-Subero, José I., Kreuz, Markus, Bibikova, Marina, Bentink, Stefan, Ammerpohl, Ole, Wickham-Garcia, Eliza, Rosolowski, Maciej, Richter, Julia, Lopez-Serra, Lidia, Ballestar, Esteban, Berger, Hilmar, Agirre, Xabier, Bernd, Heinz-Wolfram, Calvanese, Vincenzo, Cogliatti, Sergio B., Drexler, Hans G., Fan, Jian-Bing, Fraga, Mario F., Hansmann, Martin L., Hummel, Michael, Klapper, Wolfram, Korn, Bernhard, Küppers, Ralf, Macleod, Roderick A. F., Möller, Peter, Ott, German, Pott, Christiane, Prosper, Felipe, Rosenwald, Andreas, Schwaenen, Carsten, Schübeler, Dirk, Seifert, Marc, Stürzenhofecker, Benjamin, Weber, Michael, Wessendorf, Swen, Loeffler, Markus, Trümper, Lorenz, Stein, Harald, Spang, Rainer, Esteller, Manel, Barker, David, Hasenclever, Dirk and Siebert, Reiner (2009) New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood 113 (11), pp. 2488-2497. Fulltext not available.

Schwaenen, Carsten, Viardot, Andreas, Berger, Hilmar, Barth, Thomas F. E., Bentink, Stefa, Döhner, Hartmut, Enz, Martina, Feller, Alfred C., Hansmann, Martin-Leo, Hummel, Michael, Kestler, Hans A, Klapper, Wolfram, Kreuz, Markus, Lenze, Dido, Loeffler, Markus, Möller, Peter, Müller-Hermelink, Hans-Konrad, Ott, German, Rosolowski, Maciej, Rosenwald, Andreas, Ruf, Sandra, Siebert, Reiner, Spang, Rainer, Stein, Harald, Truemper, Lorenz, Lichter, Peter, Bentz, Martin and Wessendorf, Swen (2009) Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status. Genes, Chromosomes and Cancer 48 (1), pp. 39-54. Fulltext not available.

2008

Fröhlich, H., Beissbarth, T., Tresch, A., Kostka, D., Jacob, Juby, Spang, Rainer and Markowetz, F. (2008) Analyzing gene perturbation screens with nested effects models in R and bioconductor. Bioinformatics 24 (21), pp. 2549-2550. Fulltext not available.

Bentink, Stefan, Wessendorf, S., Schwaenen, C., Rosolowski, M., Klapper, W., Rosenwald, A., Ott, G., Banham, A. H., Berger, H., Feller, A. C., Hansmann, M. L., Hasenclever, D., Hummel, M., Lenze, D., Möller, P., Stuerzenhofecker, B., Loeffler, M., Truemper, L., Stein, H., Siebert, R. and Spang, Rainer (2008) Pathway activation patterns in diffuse large B-cell lymphomas. Leukemia 22 (9), pp. 1746-1754. Fulltext not available.

Klapper, W., Szczepanowski, M., Burkhardt, B., Berger, H., Rosolowski, M., Bentink, Stefan, Schwaenen, C., Wessendorf, S., Spang, Rainer, Moller, P., Hansmann, M. L., Bernd, H. W., Ott, G., Hummel, M., Stein, H., Loeffler, M., Trumper, L., Zimmermann, M., Reiter, A. and Siebert, R. (2008) Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials. Blood 112 (4), pp. 1374-1381. Fulltext not available.

Dierlamm, J., Murga Penas, E. M., Bentink, Stefan, Wessendorf, S., Berger, H., Hummel, M., Klapper, W., Lenze, D., Rosenwald, A., Haralambieva, E., Ott, G., Cogliatti, S. B., Möller, Peter, Schwaenen, C., Stein, H., Löffler, M., Spang, Rainer, Trumper, L. and Siebert, Reiner (2008) Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma. Haematologica 93 (5), pp. 688-696.

Jacob, Juby, Jentsch, M., Kostka, Dennis, Bentink, Stefan and Spang, Rainer (2008) Detecting hierarchical structure in molecular characteristics of disease using transitive approximations of directed graphs. Bioinformatics 24 (7), pp. 995-1001. Fulltext not available.

Lottaz, Claudio, Kostka, Dennis and Spang, Rainer (2008) 26. Classification of Patients. In: Lengauer, Thomas, (ed.) Bioinformatics-From Genomes to Therapies. Wiley-VCH, Weinheim, pp. 957-991. ISBN 9783527619368 (online). Fulltext not available.

Hirsch, Burkhard, Hummel, M., Bentink, Stefan, Fouladi, F., Spang, Rainer, Zollinger, R., Stein, H. and Durkop, H. (2008) CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. The American Journal of Pathology 172 (2), pp. 510-520. Fulltext not available.

Montesinos-Rongen, M,, Brunn, A,, Bentink, Stefan, Basso, K,, Lim, W, K,, Klapper, Wolfram, Schaller, C,, Reifenberger, G,, Rubenstein, J,, Wiestler, O, D,, Spang, Rainer, Dalla-Favera, R,, Siebert, Reiner and Deckert, M, (2008) Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell. Leukemia 22 (2), pp. 400-405. Fulltext not available.

Kostka, Dennis and Spang, Rainer (2008) Microarray Based Diagnosis Profits from Better Documentation of Gene Expression Signatures. PLoS Computational Biology 4 (2), e22.

Lottaz, Claudio, Kostka, Dennis, Markowetz, Florian and Spang, Rainer (2008) 15. Computational diagnostics with gene expression profiles. In: Bioinformatics. Methods in Molecular Biology, 453 (15). Humana Press, Totowa, NJ, pp. 281-296. ISBN 978-1-60327-428-9. Fulltext not available.

2007

Roesch, Alexander, Becker, Bernd, Bentink, Stefan, Spang, Rainer, Vogl, Annegret, Hagen, Ilja, Landthaler, Michael and Vogt, Thomas (2007) Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Prevention 16 (11), pp. 2486-2490. Fulltext not available.

Lottaz, Claudio, Toedling, Joern and Spang, Rainer (2007) Annotation-based distance measures for patient subgroup discovery in clinical microarray studies. Bioinformatics 23 (17), pp. 2256-2264. Fulltext not available.

Markowetz, Florian and Spang, Rainer (2007) Inferring cellular networks - a review. BMC bioinformatics 8 Suppl 6, S5.

Markowetz, F., Kostka, D., Troyanskaya, O. G. and Spang, Rainer (2007) Nested effects models for high-dimensional phenotyping screens. Bioinformatics 23 (13), i305-i312.

Scheid, Stefanie and Spang, Rainer (2007) Compensating for unknown confounders in microarray data analysis using filtered permutations. Journal of computational biology 14 (5), pp. 669-681. Fulltext not available.

Scheid, Stefanie and Spang, Rainer (2007) Compensating for unknown confounders in microarray data analysis using filtered permutations. Journal of Computational Biology 14 (5), pp. 669-681. Fulltext not available.

Rhein, P., Scheid, S., Ratei, R., Hagemeier, C., Seeger, K., Kirschner-Schwabe, R., Moericke, A., Schrappe, M., Spang, Rainer, Ludwig, W.-D. and Karawajew, L. (2007) Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia. Leukemia 21 (5), pp. 897-905. Fulltext not available.

Jaeger, Jochen, Koczan, Dirk, Thiesen, Hans-Juergen, Ibrahim, Saleh M., Gross, Gerd, Spang, Rainer and Kunz, Manfred (2007) Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues. Clinical cancer research 13 (3), pp. 806-815. Fulltext not available.

2006

Jaeger, J. and Spang, Rainer (2006) Selecting normalization genes for small diagnostic microarrays. BMC Bioinformatics 7, p. 388.

Kirschner-Schwabe, R., Lottaz, Claudio, Todling, J., Rhein, P., Karawajew, L., Eckert, C., von Stackelberg, A., Ungethum, U., Kostka, Dennis, Kulozik, A. E., Ludwig, W. D., Henze, G., Spang, Rainer, Hagemeier, C. and Seeger, K. (2006) Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia. Clinical Cancer Research 12 (15), pp. 4553-4561. Fulltext not available.

Lottaz, Claudio, Yang, Xinan, Scheid, Stefanie and Spang, Rainer (2006) OrderedList - a bioconductor package for detecting similarity in ordered gene lists. Bioinformatics 22 (18), pp. 2315-2316. Fulltext not available.

Hummel, M., Bentink, S., Berger, H., Klapper, W., Wessendorf, S., Barth, T. F., Bernd, H. W., Cogliatti, S. B., Dierlamm, J., Feller, A. C. and Spang, Rainer (2006) A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. New England Journal of Medicine 354 (23), pp. 2419-2430. Fulltext not available.

Toedling, J., Rhein, P., Ratei, R., Karawajew, L. and Spang, Rainer (2006) Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring. BMC Bioinformatics 7, p. 282.

Yang, X., Bentink, S., Scheid, S. and Spang, Rainer (2006) Similarities of ordered gene lists. Journal of Bioinformatics and Computational BiologyJ Bioinform Comput Biol 4 (3), pp. 693-708. Fulltext not available.

2005

Markowetz, F., Bloch, J. and Spang, Rainer (2005) Non-transcriptional pathway features reconstructed from secondary effects of RNA interference. Bioinformatics 21 (21), pp. 4026-4032. Fulltext not available.

Yang, X., Bentink, Stefan and Spang, Rainer (2005) Detecting common gene expression patterns in multiple cancer outcome entities. Biomedical Microdevices 7 (3), pp. 247-251. Fulltext not available.

Lottaz, Claudio and Spang, Rainer (2005) stam – a Bioconductor compliant R package for structured analysis of microarray data. BMC Bioinformatics 6, p. 211.

Scheid, S. and Spang, Rainer (2005) twilight; a Bioconductor package for estimating the local false discovery rate. Bioinformatics 21 (12), pp. 2921-2922. Fulltext not available.

Jaeger, J., Weichenhan, D., Ivandic, B. and Spang, Rainer (2005) Early diagnostic marker panel determination for microarray based clinical studies. Statistical Applications in Genetics and Molecular Biology 4 (1), article 9. Fulltext not available.

Lottaz, Claudio and Spang, Rainer (2005) Molecular decomposition of complex clinical phenotypes using biologically structured analysis of microarray data. Bioinformatics 21 (9), pp. 1971-1978.

Lottaz, Claudio, Kostka, Dennis, Markowetz, Florian and Spang, Rainer (2005) Traces of molecular disease mechanisms on microarrays. Methods in Molecular Biology 453, pp. 281-296. Fulltext not available.

2004

Kostka, Dennis and Spang, Rainer (2004) Finding disease specific alterations in the co-expression of genes. Bioinformatics 20 Suppl 1, i194-i199. Fulltext not available.

Scheid, Stefanie and Spang, Rainer (2004) A stochastic downhill search algorithm for estimating the local false discovery rate. IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB 1 (3), pp. 98-108. Fulltext not available.

2003

Blaxall, B. C., Spang, Rainer, Rockman, H. A. and Koch, W. J. (2003) Differential myocardial gene expression in the development and rescue of murine heart failure. Physiological Genomics 15 (2), pp. 105-114. Fulltext not available.

Grzeskowiak, R., Witt, Henning, Drungowski, M., Thermann, R., Hennig, S., Perrot, A., Osterziel, K., Klingbiel, D., Scheid, Stefanie and Spang, Rainer (2003) Expression profiling of human idiopathic dilated cardiomyopathy. Cardiovascular Research 59, pp. 400-411. Fulltext not available.

2002

Muller, Tobias, Spang, Rainer and Vingron, M. (2002) Estimating amino acid substitution models: a comparison of Dayhoff's estimator, the resolvent approach and a maximum likelihood method. Molecular Biology and Evolution 19 (1), pp. 8-13. Fulltext not available.

Spang, Rainer, Rehmsmeier, M. and Stoye, J. (2002) A novel approach to remote homology detection: jumping alignments. Journal of Computational Biology 9 (5), pp. 747-760. Fulltext not available.

Spang, Rainer, Zuzan, H., West, M., Nevins, J., Blanchette, C. and Marks, J. R. (2002) Prediction and uncertainty in the analysis of gene expression profiles. In Silico Biology 2 (3), pp. 369-381. Fulltext not available.

2001

West, M., Blanchette, C., Dressman, H., Huang, E., Ishida, S., Spang, Rainer, Zuzan, H., Olson, J. A., Marks, J. R. and Nevins, J. R. (2001) Predicting the clinical status of human breast cancer by using gene expression profiles. Proc. Natl. Acad. Sci. U.S.A. 98 (20), pp. 11462-11467. Fulltext not available.

Ishida, S., Huang, E., Zuzan, H., Spang, Rainer, Leone, G., West, M. and Nevins, J. R. (2001) Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol. Cell. Biol. 21 (14), pp. 4684-4699. Fulltext not available.

Spang, Rainer and Vingron, M. (2001) Limits of homology detection by pairwise sequence comparison. Bioinformatics 17 (4), pp. 338-342. Fulltext not available.

2000

Spang, Rainer, Rehmsmeier, M. and Stoye, J. (2000) Sequence database search using jumping alignments. Proc Int Conf Intell Syst Mol Biol 8, pp. 367-375. Fulltext not available.

1998

Spang, Rainer and Vingron, M. (1998) Statistics of large-scale sequence searching. Bioinformatics 14 (3), pp. 279-284. Fulltext not available.

This list was generated on Wed Feb 26 19:54:48 2020 CET.
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