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Schweihofer, Verena, Schulz, Daniela
, Blazquez, Raquel
, Brockhoff, Gero
, Ettl, Tobias
, Fiedler, Mathias
, Heimer, Sina, Schikora, Juliane, Bauer, Richard J.
und Wege, Anja Kathrin
(2025)
Multiplexed immune profiling and 3D co-culture assays to assess the individual checkpoint therapy response in head and neck squamous cell carcinoma.
Frontiers in Oncology 15.
Goerg, Alina, Piendl, Gerhard, Albert, Veruschka, Ortmann, Olaf
, Wege, Anja Kathrin
und Brockhoff, Gero
(2025)
Mdm2 targeting via PROteolysis TArgeting Chimeras (PROTAC) is efficient in p53 wildtype, p53-mutated, and abemaciclib-resistant estrogen receptor-positive cell lines and superior to mdm2 inhibition.
BMC Cancer 25 (1).
Schweihofer, Verena, Bruss, Christina, Seitz, Stephan, Glehr, Gunther
, Hetterich, Madeleine, Weber, Florian
, Hatzipanagiotou, Maria Eleni
, Fernández-Pacheco Álvarez, Miriam, Ortmann, Olaf
, Brockhoff, Gero
, Bauer, Richard J.
und Wege, Anja Kathrin
(2025)
Breast cancer scoring based on a multiplexed profiling of soluble and cell-associated (immune) markers facilitates the prediction of pembrolizumab therapy.
Cancer Cell International 25, S. 120.
Bruss, Christina, Kellner, Kerstin, Ortmann, Olaf
, Seitz, Stephan, Brockhoff, Gero
, Hutchinson, James A.
und Wege, Anja Kathrin
(2022)
Advanced Immune Cell Profiling by Multiparameter Flow Cytometry in Humanized Patient-Derived Tumor Mice.
Cancers 14 (9), S. 2214.
Wege, Anja Kathrin, Rom‐Jurek, Eva‐Maria, Jank, Paul, Denkert, Carsten, Ugocsai, Peter, Solbach, Christine, Blohmer, Jens‐Uwe, Sinn, Bruno, Mackelenbergh, Marion, Möbus, Volker, Trumpp, Andreas, Marangoni, Elisabetta, Pfarr, Nicole, Irlbeck, Christoph
, Warfsmann, Jens, Polzer, Bernhard
, Weber, Florian, Ortmann, Olaf
, Loibl, Sibylle, Vladimirova, Valentina und Brockhoff, Gero
(2021)
mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease.
International Journal of Cancer 150, S. 1357-1372.
Wege, Anja Kathrin
, Dreyer, Tobias F., Teoman, Attila, Ortmann, Olaf
, Brockhoff, Gero und Bronger, Holger
(2021)
CX3CL1 Overexpression Prevents the Formation of Lung Metastases in Trastuzumab-Treated MDA-MB-453-Based Humanized Tumor Mice (HTM).
Cancers 2021 (13), S. 2459.
(Eingereicht)
, Weber, Florian, Schwab, Albrecht, Wege, Anja Kathrin, Nedvetsky, Pavel und Krahn, Michael P.
(2021)
Pals1 prevents Rac1-dependent colorectal cancer cell metastasis by inhibiting Arf6.
Molecular Cancer 20 (1).
Volltext nicht vorhanden.
, Münz, Christian, Schuringa, Jan Jacob, Bissig, Karl‐Dimiter, Soper, Brian, Meeham, Terrence, Yao, Li‐Chin, Di Santo, James P.
, Brehm, Michael, Rodriguez, Estefania, Wege, Anja Kathrin, Bonnet, Dominique, Guionaud, Silvia, Howard, Kristina E., Kitchen, Scott, Klein, Florian, Saeb‐Parsy, Kourosh, Sam, Johannes, Sharma, Amar Deep, Trumpp, Andreas
, Trusolino, Livio
, Bult, Carol und Shultz, Leonard
(2020)
Innovations, challenges, and minimal information for standardization of humanized mice.
EMBO Molecular Medicine 12 (7).
Volltext nicht vorhanden.
, Krautbauer, Sabrina, Liebisch, Gerhard
, Wege, Anja Kathrin
, Melter, Michael
und Weiss, Thomas S.
(2019)
Bile acid-induced apoptosis and bile acid synthesis are reduced by over-expression of Augmenter of Liver Regeneration (ALR) in a STAT3-dependent mechanism.
Experimental Cell Research 374 (1), S. 189-197.
Volltext nicht vorhanden.
Wege, Anja Kathrin, Chittka, Dominik, Buchholz, Stefan, Klinkhammer-Schalke, Monika, Diermeier-Daucher, Simone, Zeman, Florian, Ortmann, Olaf und Brockhoff, Gero
(2018)
HER4 expression in estrogen receptor-positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women.
Breast Cancer Research 20 (1), S. 1-15.
Zimara, Nicole, Chanyalew, Menberework, Aseffa, Abraham
, van Zandbergen, Ger, Lepenies, Bernd, Schmid, Maximilian, Weiss, Richard
, Rascle, Anne, Wege, Anja Kathrin, Jantsch, Jonathan, Schatz, Valentin, Brown, Gordon D. und Ritter, Uwe
(2018)
Dectin-1 Positive Dendritic Cells Expand after Infection with Leishmania major Parasites and Represent Promising Targets for Vaccine Development.
Frontiers in Immunology 9 (263), S. 1-20.
Brockhoff, Gero, Seitz, Stephan, Weber, Florian, Zeman, Florian, Klinkhammer-Schalke, Monika, Ortmann, Olaf und Wege, Anja Kathrin
(2018)
The presence of PD-1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease.
Oncotarget 2018 (9), S. 6201-6212.
Wege, Anja Kathrin, Florian, Christian, Ernst, Wolfgang, Zimara, Nicole, Schleicher, Ulrike, Hanses, Frank, Schmid, Maximilian und Ritter, Uwe
(2012)
Leishmania major Infection in Humanized Mice Induces Systemic Infection and Provokes a Nonprotective Human Immune Response.
PLoS Neglected Tropical Diseases 6, e1741.
, Sack, Ulrich und Lange, Franziska
(2012)
Comparison of Hematopoietic Stem Cells Derived from Fresh and Cryopreserved Whole Cord Blood in the Generation of Humanized Mice.
PLoS ONE 7 (10), e46772.
Volltext nicht vorhanden.
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