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- URN to cite this document:
- urn:nbn:de:bvb:355-opus-3176
- DOI to cite this document:
- 10.5283/epub.10240
Abstract (German)
In der Literatur sind verschiedene humane und murine Subpopulationen von Suppressor T-Lymphozyten beschrieben, die in der Lage sind, zumeist über lösliche Faktoren wie z.B. IL-10 oder TGF-beta eine Suppression aktivierter T-Zellen einzuleiten. Eine hochspezifische Form der Suppression, bei welcher es zu einer Deletion aktivierter, zytotoxischer T-Zellen (CTL) über deren T-Zell-Rezeptor (TCR) ...
Translation of the abstract (English)
Several subpopulations of various human and murine suppressor T lymphocytes are described in the literature, which are capable of suppressing activated T cells, mostly via soluble factos such as IL-10 and TGF-beta. Already a highly specific form of suppression could be shown for the murine system, in which cytotoxic T cells (CTL) are deleted via their T cell receptor (TCR) (Zhang ZX et al. Nat. ...