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Analyses of the archaeal transcription cycle reveal a mosaic of eukaryotic RNA polymerase II and III-like features

URN to cite this document:
urn:nbn:de:bvb:355-opus-9490
Spitalny, Patrizia
Date of publication of this fulltext: 23 Jan 2009 15:23


Abstract (English)

Novel mechanistic properties of the archaeal transcription system that reveal similarities especially to the eukaryotic RNA polymerase II and III systems were presented in thesis. The in vitro transcription system from the hyperthermophilic archaeon Pyrococcus furiosus provided the basis for the studies of the archaeal transcription cycle in the present work. To obtain a detailed view on the ...

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Translation of the abstract (German)

Die vorliegende Arbeit führt zu neuen Einblicken in den Mechanismus des archaeellen Transkriptionssystems und offenbart Ähnlichkeiten insbesondere zu den eukaryotischen RNA Polymerase II und III Systemen. Das in vitro Transkriptionssystem des hyperthermophilen Archaeons Pyrococcus furiosus bildete die Grundlage für die Untersuchung des archaeellen Transkriptionszyklus in dieser Arbeit. Um ein ...

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