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The interleukin-2 receptor in human monocytes and macrophages: regulation of expression and release of the alpha and beta chains (p55 and p75)

Scheibenbogen, C., Keilholz, U., Richter, M., Andreesen, Reinhard and Hunstein, W. (1992) The interleukin-2 receptor in human monocytes and macrophages: regulation of expression and release of the alpha and beta chains (p55 and p75). Research in immunology 143 (1), pp. 33-7.

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Abstract

Human monocytes constitutively express the intermediate-affinity interleukin-2 receptor (IL2R) p75, while freshly isolated monocytes lack the low-affinity IL2R p55 (Tac antigen, CD25). Lipopolysaccharide (LPS) upregulates expression of p75 and effectively induces surface expression of CD25 on human monocytes within 18 h, as detected by two-colour FACS analysis on 59.5 +/- 7.6% of cells. ...

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Item type:Article
Date:1992
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
ValueType
1565844PubMed ID
Classification:
NotationType
HumansMESH
Macrophage ActivationMESH
Macrophages/immunologyMESH
Molecular WeightMESH
Monocytes/immunologyMESH
Protein ConformationMESH
Receptors, Interleukin-2/metabolismMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:14279
Owner only: item control page
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