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Zinc(II)cyclen in molecular recognition & new water-soluble cholesterol derivatives

Schmidt, Florian (2011) Zinc(II)cyclen in molecular recognition & new water-soluble cholesterol derivatives. PhD, Universität Regensburg.

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Date of publication of this fulltext: 04 May 2011 08:46

Abstract (English)

Chapter 1 of this work deals with pyrene-excimer signalled analyte recognition of small biomolecules. Therefore, pyrene labelled Zn2+-cyclen and bis-Zn2+-bis-cyclen complexes were synthesized. The reversible coordination at physiological pH of Zn2+-cyclens to phosphate anions and to imide moieties, as present in thymine and uracil nucleotides, is well known. In the presence of analytes bearing a ...


Translation of the abstract (German)

In Kapitel 1 dieser Arbeit wird die molekulare Unterscheidung von kleinen Biomolekülen mittels Analyt-induzierter Pyren-Excimer-Fluoreszenz gezeigt. Die reversible Koordination von Zn2+-Cyclenen an Phosphatanionen und Imide unter physiologischen Bedingungen ist literaturbekannt. Diese Eigenschaft von Zn2+-Cyclen Komplexen in Kombination mit Pyren als Fluorophor führte im Fall von Thymin- und ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:4 May 2011
Referee:Prof. Dr. Burkhard König and Prof. Dr. Hans-Achim Wagenknecht
Date of exam:18 June 2010
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Keywords:Molecular recognition, water-soluble cholesterol, nucleotides, nucleic acids, DNA staining, protein staining, phosphorylation, protein-protein interaction, Ras Molekular Erkennung; wasserlösliches Cholesterin; Nukleotide; Nukleinsäuren; DNA Färbung; Protein Färbung, Phosphorylierung; Protein-Protein Interaktion; Ras
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:15614
Owner only: item control page


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