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Characterization of a novel M-CSF induced effector macrophage

Riedhammer, Sebastian Matthias (2010) Characterization of a novel M-CSF induced effector macrophage. PhD, Universität Regensburg.

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Dissertation Sebastian Riedhammer 2010
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Date of publication of this fulltext: 15 Jul 2010 14:23

Abstract (English)

The results of this study establish that monocyte adhesion, which undoubtedly is responsible for many substantial changes in the monocyte, is not essential for monocyte survival and differentiation to a macrophage-like cell. As monocytes and their dfferentiated forms are found, not only in the extra cellular matrix, but also in suspension in the blood and the peritoneal fluid, this can help to ...


Translation of the abstract (German)

Monozyten und die aus ihnen hervorgehenden Makrophagen und dendritischen Zellen (DC) haben im Immunsystem des Menschen eine besondere Rolle als Bindeglied zwischen dem angeborenen und dem adaptiven Immunsystem. In vielen Experimenten zur Differenzierung von Makrophagen aus Monozyten erwies sich der Wachstumsfaktor M-CSF als überlebensnotwendig. Dabei wurden jedoch die Monozyten stets adhärent ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:15 July 2010
Referee:Prof. Dr. Michael Rehli and Prof. Dr. Michael Melter
Date of exam:5 July 2010
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Interdisciplinary Subject Network:Not selected
Keywords:Monocyte, Macrophage, Adhesion, M-CSF
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:15685
Owner only: item control page


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