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Ex vivo/in vitro absorption of STW 5 (Iberogast) and its extract components

Kelber, O. ; Wittwer, A. ; Lapke, C. ; Kroll, U. ; Weiser, D. ; Okpanyi, S. N. ; Heilmann, Jörg


To correlate the pharmacol. effects of the fixed herbal combination STW 5 (Iberogast) contg. nine ext. components with its confirmed clin. efficacy, ex vivo/in vitro absorption tests were performed. For the investigation, the everted gut sac technique and, in a pilot study, the Caco-2-cell model were used. The absorption rate of the exts. was detd. by measuring characteristic marker substances of ...


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